{"id":"https://openalex.org/W3029836473","doi":"https://doi.org/10.1093/bioinformatics/btaa544","title":"DeepCDA: deep cross-domain compound\u2013protein affinity prediction through LSTM and convolutional neural networks","display_name":"DeepCDA: deep cross-domain compound\u2013protein affinity prediction through LSTM and convolutional neural networks","publication_year":2020,"publication_date":"2020-05-22","ids":{"openalex":"https://openalex.org/W3029836473","doi":"https://doi.org/10.1093/bioinformatics/btaa544","mag":"3029836473","pmid":"https://pubmed.ncbi.nlm.nih.gov/32462178"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaa544","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa544","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069064010","display_name":"Karim Abbasi","orcid":"https://orcid.org/0000-0003-2135-8864"},"institutions":[{"id":"https://openalex.org/I23946033","display_name":"University of Tehran","ror":"https://ror.org/05vf56z40","country_code":"IR","type":"education","lineage":["https://openalex.org/I23946033"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Karim Abbasi","raw_affiliation_strings":["Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics, University of Tehran , Tehran 1417614411, Iran"],"affiliations":[{"raw_affiliation_string":"Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics, University of Tehran , Tehran 1417614411, Iran","institution_ids":["https://openalex.org/I23946033"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018861719","display_name":"Parvin Razzaghi","orcid":"https://orcid.org/0000-0002-7031-4609"},"institutions":[{"id":"https://openalex.org/I161028277","display_name":"Institute for Advanced Studies in Basic Sciences","ror":"https://ror.org/00bzsst90","country_code":"IR","type":"education","lineage":["https://openalex.org/I161028277"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Parvin Razzaghi","raw_affiliation_strings":["Department of Computer Science and Information Technology, Institute for Advanced Studies in Basic Sciences (IASBS) , Zanjan 4513766731, Iran"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Information Technology, Institute for Advanced Studies in Basic Sciences (IASBS) , Zanjan 4513766731, Iran","institution_ids":["https://openalex.org/I161028277"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074083544","display_name":"Antti Poso","orcid":"https://orcid.org/0000-0003-4196-4204"},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Antti Poso","raw_affiliation_strings":["School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland , Kuopio 80100, Finland"],"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland , Kuopio 80100, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026902416","display_name":"Massoud Amanlou","orcid":"https://orcid.org/0000-0002-8559-1668"},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Massoud Amanlou","raw_affiliation_strings":["Department of Medicinal Chemistry, Drug Design and Development Research Center, Tehran University of Medical Sciences , Tehran 1416753955, Iran"],"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry, Drug Design and Development Research Center, Tehran University of Medical Sciences , Tehran 1416753955, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021441524","display_name":"Jahan B. Ghasemi","orcid":"https://orcid.org/0000-0002-0380-8000"},"institutions":[{"id":"https://openalex.org/I23946033","display_name":"University of Tehran","ror":"https://ror.org/05vf56z40","country_code":"IR","type":"education","lineage":["https://openalex.org/I23946033"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Jahan B Ghasemi","raw_affiliation_strings":["Chemistry Department, Faculty of Sciences, University of Tehran , Tehran 1417614418, Iran"],"affiliations":[{"raw_affiliation_string":"Chemistry Department, Faculty of Sciences, University of Tehran , Tehran 1417614418, Iran","institution_ids":["https://openalex.org/I23946033"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030421501","display_name":"Ali Masoudi\u2010Nejad","orcid":"https://orcid.org/0000-0003-0659-5183"},"institutions":[{"id":"https://openalex.org/I23946033","display_name":"University of Tehran","ror":"https://ror.org/05vf56z40","country_code":"IR","type":"education","lineage":["https://openalex.org/I23946033"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Ali Masoudi-Nejad","raw_affiliation_strings":["Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics, University of Tehran , Tehran 1417614411, Iran"],"affiliations":[{"raw_affiliation_string":"Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics, University of Tehran , Tehran 1417614411, Iran","institution_ids":["https://openalex.org/I23946033"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5030421501"],"corresponding_institution_ids":["https://openalex.org/I23946033"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":16.1857,"has_fulltext":false,"cited_by_count":274,"citation_normalized_percentile":{"value":0.99255393,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"36","issue":"17","first_page":"4633","last_page":"4642"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7706733345985413},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.6631718873977661},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6536683440208435},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6303747892379761},{"id":"https://openalex.org/keywords/encode","display_name":"ENCODE","score":0.6249987483024597},{"id":"https://openalex.org/keywords/encoder","display_name":"Encoder","score":0.6122190952301025},{"id":"https://openalex.org/keywords/encoding","display_name":"Encoding (memory)","score":0.5948739647865295},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5610795021057129},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.501683235168457},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5005722045898438},{"id":"https://openalex.org/keywords/test-data","display_name":"Test data","score":0.48379844427108765},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.46139833331108093},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.4418216347694397},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4381735324859619},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.42412593960762024},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.07625687122344971},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.07533082365989685}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7706733345985413},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.6631718873977661},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6536683440208435},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6303747892379761},{"id":"https://openalex.org/C66746571","wikidata":"https://www.wikidata.org/wiki/Q1134833","display_name":"ENCODE","level":3,"score":0.6249987483024597},{"id":"https://openalex.org/C118505674","wikidata":"https://www.wikidata.org/wiki/Q42586063","display_name":"Encoder","level":2,"score":0.6122190952301025},{"id":"https://openalex.org/C125411270","wikidata":"https://www.wikidata.org/wiki/Q18653","display_name":"Encoding (memory)","level":2,"score":0.5948739647865295},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5610795021057129},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.501683235168457},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5005722045898438},{"id":"https://openalex.org/C16910744","wikidata":"https://www.wikidata.org/wiki/Q7705759","display_name":"Test data","level":2,"score":0.48379844427108765},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.46139833331108093},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.4418216347694397},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4381735324859619},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.42412593960762024},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07625687122344971},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.07533082365989685},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btaa544","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa544","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32462178","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32462178","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:erepo.uef.fi:123456789/24453","is_oa":false,"landing_page_url":"https://erepo.uef.fi/handle/123456789/24453","pdf_url":null,"source":{"id":"https://openalex.org/S4306402418","display_name":"UEF eRepo (University of Eastern Finland)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I175532246","host_organization_name":"University of Eastern Finland","host_organization_lineage":["https://openalex.org/I175532246"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Tieteelliset aikakauslehtiartikkelit"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W68293321","https://openalex.org/W1972987731","https://openalex.org/W1975147762","https://openalex.org/W2035585923","https://openalex.org/W2050418754","https://openalex.org/W2064675550","https://openalex.org/W2086286404","https://openalex.org/W2096864392","https://openalex.org/W2101279411","https://openalex.org/W2109991441","https://openalex.org/W2123099218","https://openalex.org/W2130942839","https://openalex.org/W2133564696","https://openalex.org/W2145962544","https://openalex.org/W2169678694","https://openalex.org/W2178378573","https://openalex.org/W2213443318","https://openalex.org/W2259538443","https://openalex.org/W2290847742","https://openalex.org/W2407521645","https://openalex.org/W2471196942","https://openalex.org/W2533800772","https://openalex.org/W2592742128","https://openalex.org/W2593768305","https://openalex.org/W2605952223","https://openalex.org/W2770363598","https://openalex.org/W2783391889","https://openalex.org/W2785947426","https://openalex.org/W2786429113","https://openalex.org/W2798377719","https://openalex.org/W2806592685","https://openalex.org/W2809216727","https://openalex.org/W2860192827","https://openalex.org/W2888000811","https://openalex.org/W2904910227","https://openalex.org/W2906755148","https://openalex.org/W2919115771","https://openalex.org/W2922701384","https://openalex.org/W2949888546","https://openalex.org/W2950800384","https://openalex.org/W2952677200","https://openalex.org/W2955244377","https://openalex.org/W2964283682","https://openalex.org/W2964308564","https://openalex.org/W2982691277","https://openalex.org/W2986661129","https://openalex.org/W3099097979","https://openalex.org/W3100157108","https://openalex.org/W6602843372","https://openalex.org/W6678415854","https://openalex.org/W6679434410","https://openalex.org/W6679436768","https://openalex.org/W6714138976","https://openalex.org/W6747808759","https://openalex.org/W6748056225","https://openalex.org/W6750689453","https://openalex.org/W6759255826"],"related_works":["https://openalex.org/W1950940422","https://openalex.org/W2372020181","https://openalex.org/W2129146436","https://openalex.org/W2156531654","https://openalex.org/W4378714697","https://openalex.org/W2253069048","https://openalex.org/W1581723585","https://openalex.org/W2294330161","https://openalex.org/W2804553224","https://openalex.org/W4283822356"],"abstract_inverted_index":{"https://github.com/LBBSoft/DeepCDA.":[0]},"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":74},{"year":2024,"cited_by_count":68},{"year":2023,"cited_by_count":46},{"year":2022,"cited_by_count":43},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":2}],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2025-10-10T00:00:00"}