{"id":"https://openalex.org/W3212699149","doi":"https://doi.org/10.1093/bib/bbab496","title":"Immuno-informatics analysis predicts B and T cell consensus epitopes for designing peptide vaccine against SARS-CoV-2 with 99.82% global population coverage","display_name":"Immuno-informatics analysis predicts B and T cell consensus epitopes for designing peptide vaccine against SARS-CoV-2 with 99.82% global population coverage","publication_year":2021,"publication_date":"2021-11-06","ids":{"openalex":"https://openalex.org/W3212699149","doi":"https://doi.org/10.1093/bib/bbab496","mag":"3212699149"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbab496","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbab496","pdf_url":"https://academic.oup.com/bib/article-pdf/23/1/bbab496/42229894/bbab496.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bib/article-pdf/23/1/bbab496/42229894/bbab496.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Priyank Shukla","orcid":"https://orcid.org/0000-0002-4985-9305"},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]},{"id":"https://openalex.org/I2802259370","display_name":"Altnagelvin Area Hospital","ror":"https://ror.org/05xxmnm27","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802259370","https://openalex.org/I4210094355"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Priyank Shukla","raw_affiliation_strings":["Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK"],"affiliations":[{"raw_affiliation_string":"Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK","institution_ids":["https://openalex.org/I138801177","https://openalex.org/I2802259370"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Preeti Pandey","orcid":null},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Preeti Pandey","raw_affiliation_strings":["Department of Cell and Molecular Pharmacology and Experimental Therapeutics, College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA"],"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Pharmacology and Experimental Therapeutics, College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bodhayan Prasad","orcid":"https://orcid.org/0000-0002-7383-2460"},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]},{"id":"https://openalex.org/I2802259370","display_name":"Altnagelvin Area Hospital","ror":"https://ror.org/05xxmnm27","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802259370","https://openalex.org/I4210094355"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bodhayan Prasad","raw_affiliation_strings":["Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK"],"affiliations":[{"raw_affiliation_string":"Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK","institution_ids":["https://openalex.org/I138801177","https://openalex.org/I2802259370"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tony Robinson","orcid":null},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tony Robinson","raw_affiliation_strings":["School of Computing, Engineering and Intelligent Systems, Ulster University, Magee Campus, Derry/Londonderry, BT48 7JL, UK"],"affiliations":[{"raw_affiliation_string":"School of Computing, Engineering and Intelligent Systems, Ulster University, Magee Campus, Derry/Londonderry, BT48 7JL, UK","institution_ids":["https://openalex.org/I138801177"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rituraj Purohit","orcid":null},"institutions":[{"id":"https://openalex.org/I4210128326","display_name":"Institute of Himalayan Bioresource Technology","ror":"https://ror.org/03xcn0p72","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210128326","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rituraj Purohit","raw_affiliation_strings":["Structural Bioinformatics Lab, Division of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology (CSIR-IHBT), Palampur, Himachal Pradesh-176061, India"],"affiliations":[{"raw_affiliation_string":"Structural Bioinformatics Lab, Division of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology (CSIR-IHBT), Palampur, Himachal Pradesh-176061, India","institution_ids":["https://openalex.org/I4210128326"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Leon G D\u2019Cruz","orcid":null},"institutions":[{"id":"https://openalex.org/I2802802402","display_name":"Queen Alexandra Hospital","ror":"https://ror.org/04rha3g10","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802802402","https://openalex.org/I4210090003"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Leon G D\u2019Cruz","raw_affiliation_strings":["Respiratory Medicine Department and Clinical Trials Unit, Queen Alexandra Hospital, Portsmouth, PO6 3LY, UK"],"affiliations":[{"raw_affiliation_string":"Respiratory Medicine Department and Clinical Trials Unit, Queen Alexandra Hospital, Portsmouth, PO6 3LY, UK","institution_ids":["https://openalex.org/I2802802402"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Murtaza M Tambuwala","orcid":"https://orcid.org/0000-0001-8499-9891"},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Murtaza M Tambuwala","raw_affiliation_strings":["School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine Campus, Coleraine, BT52 1SA, UK"],"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine Campus, Coleraine, BT52 1SA, UK","institution_ids":["https://openalex.org/I138801177"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ankur Mutreja","orcid":null},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210156194","display_name":"Addenbrooke's Hospital","ror":"https://ror.org/055vbxf86","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802466933","https://openalex.org/I4210156194"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ankur Mutreja","raw_affiliation_strings":["Department of Medicine, University of Cambridge, Level 5, Addenbrookes Hospital, Cambridge, CB2 0QQ, UK"],"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Cambridge, Level 5, Addenbrookes Hospital, Cambridge, CB2 0QQ, UK","institution_ids":["https://openalex.org/I4210156194","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jim Harkin","orcid":null},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jim Harkin","raw_affiliation_strings":["School of Computing, Engineering and Intelligent Systems, Ulster University, Magee Campus, Derry/Londonderry, BT48 7JL, UK"],"affiliations":[{"raw_affiliation_string":"School of Computing, Engineering and Intelligent Systems, Ulster University, Magee Campus, Derry/Londonderry, BT48 7JL, UK","institution_ids":["https://openalex.org/I138801177"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Taranjit Singh Rai","orcid":null},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]},{"id":"https://openalex.org/I2802259370","display_name":"Altnagelvin Area Hospital","ror":"https://ror.org/05xxmnm27","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802259370","https://openalex.org/I4210094355"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Taranjit Singh Rai","raw_affiliation_strings":["Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK"],"affiliations":[{"raw_affiliation_string":"Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK","institution_ids":["https://openalex.org/I138801177","https://openalex.org/I2802259370"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Elaine K Murray","orcid":null},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]},{"id":"https://openalex.org/I2802259370","display_name":"Altnagelvin Area Hospital","ror":"https://ror.org/05xxmnm27","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802259370","https://openalex.org/I4210094355"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Elaine K Murray","raw_affiliation_strings":["Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK"],"affiliations":[{"raw_affiliation_string":"Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK","institution_ids":["https://openalex.org/I138801177","https://openalex.org/I2802259370"]}]},{"author_position":"middle","author":{"id":null,"display_name":"David S Gibson","orcid":null},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]},{"id":"https://openalex.org/I2802259370","display_name":"Altnagelvin Area Hospital","ror":"https://ror.org/05xxmnm27","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802259370","https://openalex.org/I4210094355"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David S Gibson","raw_affiliation_strings":["Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK"],"affiliations":[{"raw_affiliation_string":"Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK","institution_ids":["https://openalex.org/I138801177","https://openalex.org/I2802259370"]}]},{"author_position":"last","author":{"id":null,"display_name":"Anthony J Bjourson","orcid":null},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]},{"id":"https://openalex.org/I2802259370","display_name":"Altnagelvin Area Hospital","ror":"https://ror.org/05xxmnm27","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802259370","https://openalex.org/I4210094355"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anthony J Bjourson","raw_affiliation_strings":["Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK"],"affiliations":[{"raw_affiliation_string":"Northern Ireland Centre for Stratified Medicine, Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Derry/Londonderry, BT47 6SB, UK","institution_ids":["https://openalex.org/I138801177","https://openalex.org/I2802259370"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":13,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I138801177","https://openalex.org/I2802259370"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":0.732,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.69783767,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"23","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epitope","display_name":"Epitope","score":0.8894000053405762},{"id":"https://openalex.org/keywords/peptide-vaccine","display_name":"Peptide vaccine","score":0.6014999747276306},{"id":"https://openalex.org/keywords/human-leukocyte-antigen","display_name":"Human leukocyte antigen","score":0.5591999888420105},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.5077999830245972},{"id":"https://openalex.org/keywords/pandemic","display_name":"Pandemic","score":0.45489999651908875},{"id":"https://openalex.org/keywords/epitope-mapping","display_name":"Epitope mapping","score":0.4074999988079071},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.3853999972343445},{"id":"https://openalex.org/keywords/vaccine-efficacy","display_name":"Vaccine efficacy","score":0.32510000467300415}],"concepts":[{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.8894000053405762},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.630299985408783},{"id":"https://openalex.org/C2776789287","wikidata":"https://www.wikidata.org/wiki/Q7166532","display_name":"Peptide vaccine","level":4,"score":0.6014999747276306},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.5591999888420105},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5454000234603882},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5077999830245972},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.46959999203681946},{"id":"https://openalex.org/C89623803","wikidata":"https://www.wikidata.org/wiki/Q12184","display_name":"Pandemic","level":5,"score":0.45489999651908875},{"id":"https://openalex.org/C2781241564","wikidata":"https://www.wikidata.org/wiki/Q1347450","display_name":"Epitope mapping","level":4,"score":0.4074999988079071},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3853999972343445},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34470000863075256},{"id":"https://openalex.org/C2780441014","wikidata":"https://www.wikidata.org/wiki/Q7907952","display_name":"Vaccine efficacy","level":3,"score":0.32510000467300415},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.3231000006198883},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.2989000082015991},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2930000126361847},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2858999967575073},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.27799999713897705},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.2721000015735626},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.26809999346733093},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.26739999651908875},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.26440000534057617},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.26350000500679016},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.25029999017715454}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1093/bib/bbab496","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbab496","pdf_url":"https://academic.oup.com/bib/article-pdf/23/1/bbab496/42229894/bbab496.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:pure.atira.dk:openaire/4771860e-d411-4820-9857-bc211d67e897","is_oa":false,"landing_page_url":"https://pure.ulster.ac.uk/en/publications/4771860e-d411-4820-9857-bc211d67e897","pdf_url":null,"source":{"id":"https://openalex.org/S4306402454","display_name":"Ulster University Research Portal (Ulster University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I138801177","host_organization_name":"University of Ulster","host_organization_lineage":["https://openalex.org/I138801177"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Shukla, P, Pandey, P, Prasad, B, Robinson, T, Purohit, R, D'Cruz, L G, Tambuwala, M, Mutreja, A, Harkin, J, Rai, T S, Murray, EK, Gibson, D S & Bjourson, AJ 2022, 'Immuno-informatics analysis predicts B and T cell consensus epitopes for designing peptide vaccine against SARS-CoV-2 with 99.82% global population coverage', Briefings in Bioinformatics, vol. 23, no. 1, bbab496, pp. 1-15. https://doi.org/10.1093/bib/bbab496","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:eprints.gla.ac.uk:303795","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Articles"},{"id":"pmh:oai:pubmedcentral.nih.gov:8769887","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8769887","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbab496","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbab496","pdf_url":"https://academic.oup.com/bib/article-pdf/23/1/bbab496/42229894/bbab496.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2387566524","display_name":"Kelvin-2","funder_award_id":"EP/T022175/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320316507","display_name":"Coalition for Epidemic Preparedness Innovations","ror":"https://ror.org/02j9wvt50"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3212699149.pdf","grobid_xml":"https://content.openalex.org/works/W3212699149.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W28510732","https://openalex.org/W1973980688","https://openalex.org/W1982752226","https://openalex.org/W2015176909","https://openalex.org/W2019711015","https://openalex.org/W2046153984","https://openalex.org/W2097874743","https://openalex.org/W2102367710","https://openalex.org/W2131924932","https://openalex.org/W2132629607","https://openalex.org/W2216203568","https://openalex.org/W2267653167","https://openalex.org/W2587970647","https://openalex.org/W2765766142","https://openalex.org/W2884538216","https://openalex.org/W3004280078","https://openalex.org/W3005011674","https://openalex.org/W3009335299","https://openalex.org/W3011488280","https://openalex.org/W3022325117","https://openalex.org/W3022701653","https://openalex.org/W3022974266","https://openalex.org/W3042332408","https://openalex.org/W3081626042","https://openalex.org/W3106595452","https://openalex.org/W3107327505","https://openalex.org/W3111255098","https://openalex.org/W3111590711","https://openalex.org/W3113734454","https://openalex.org/W3117298986","https://openalex.org/W3119231619","https://openalex.org/W3126729284","https://openalex.org/W3127353402","https://openalex.org/W3127401064","https://openalex.org/W3128959418","https://openalex.org/W3135273148"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"The":[1,215],"current":[2],"global":[3,129,165],"pandemic":[4],"due":[5],"to":[6,65,81,104,125,231],"Severe":[7],"Acute":[8],"Respiratory":[9],"Syndrome":[10],"Coronavirus":[11],"2":[12,161],"(SARS-CoV-2)":[13],"has":[14,95],"taken":[15],"a":[16,30,156,164],"substantial":[17],"number":[18,31,160],"of":[19,32,53,89,128,137,168,177],"lives":[20],"across":[21],"the":[22,47,50,102,134,220],"world.":[23,48],"Although":[24],"few":[25],"vaccines":[26],"have":[27,101,226],"been":[28],"rolled-out,":[29],"vaccine":[33,68],"candidates":[34],"are":[35,63,112,148],"still":[36],"under":[37],"clinical":[38],"trials":[39],"at":[40],"various":[41,73],"pharmaceutical":[42],"companies":[43],"and":[44,57,76,85,108,114,145,147,175,190,210,219],"laboratories":[45],"around":[46],"Considering":[49],"intrinsic":[51],"nature":[52],"viruses":[54],"in":[55],"mutating":[56],"evolving":[58],"over":[59],"time,":[60],"persistent":[61],"efforts":[62,230],"needed":[64],"develop":[66,232],"better":[67],"candidates.":[69],"In":[70],"this":[71],"study,":[72],"immuno-informatics":[74,216],"tools":[75],"bioinformatics":[77],"databases":[78],"were":[79,122],"deployed":[80],"derive":[82],"consensus":[83],"B-cell":[84],"T-cell":[86,180],"epitope":[87],"sequences":[88,121],"SARS-CoV-2":[90,151,235],"spike":[91],"glycoprotein.":[92],"This":[93],"approach":[94],"identified":[96],"four":[97],"potential":[98],"epitopes":[99,181,222],"which":[100],"capability":[103],"initiate":[105],"both":[106,142],"antibody":[107],"cell-mediated":[109],"immune":[110],"responses,":[111],"non-allergenic":[113],"do":[115],"not":[116],"trigger":[117],"autoimmunity.":[118],"These":[119],"peptide":[120],"also":[123],"evaluated":[124],"show":[126],"99.82%":[127],"population":[130,166],"coverage":[131,167],"based":[132],"on":[133],"genotypic":[135],"frequencies":[136],"HLA":[138,185],"binding":[139,174,197],"alleles":[140],"for":[141,150],"MHC":[143],"class-I":[144],"class-II":[146],"unique":[149],"isolated":[152],"from":[153],"human":[154],"as":[155],"host":[157],"species.":[158],"Epitope":[159],"alone":[162],"had":[163],"98.2%.":[169],"Therefore,":[170],"we":[171],"further":[172],"validated":[173],"interaction":[176],"its":[178],"constituent":[179],"with":[182,201],"their":[183],"corresponding":[184],"proteins":[186],"using":[187],"molecular":[188,191,202],"docking":[189],"dynamics":[192,208],"simulation":[193],"experiments,":[194],"followed":[195],"by":[196],"free":[198,211],"energy":[199,212],"calculations":[200],"mechanics":[203],"Poisson\u2013Boltzmann":[204],"surface":[205],"area,":[206],"essential":[207],"analysis":[209],"landscape":[213],"analysis.":[214],"pipeline":[217],"described":[218],"candidate":[221],"discovered":[223],"herein":[224],"could":[225],"significant":[227],"impact":[228],"upon":[229],"globally":[233],"effective":[234],"vaccines.":[236]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2}],"updated_date":"2026-04-15T08:11:43.952461","created_date":"2021-11-22T00:00:00"}
