{"id":"https://openalex.org/W3139686515","doi":"https://doi.org/10.1093/bib/bbab083","title":"Comprehensive assessment of machine learning-based methods for predicting antimicrobial peptides","display_name":"Comprehensive assessment of machine learning-based methods for predicting antimicrobial peptides","publication_year":2021,"publication_date":"2021-02-23","ids":{"openalex":"https://openalex.org/W3139686515","doi":"https://doi.org/10.1093/bib/bbab083","mag":"3139686515","pmid":"https://pubmed.ncbi.nlm.nih.gov/33774670"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbab083","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbab083","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042066408","display_name":"Jing Xu","orcid":"https://orcid.org/0000-0001-8532-2241"},"institutions":[{"id":"https://openalex.org/I2799424032","display_name":"Discovery Institute","ror":"https://ror.org/05t8s3y29","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2799424032"]},{"id":"https://openalex.org/I2801239119","display_name":"Australian Regenerative Medicine Institute","ror":"https://ror.org/02qa5kg76","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801037857","https://openalex.org/I2801239119","https://openalex.org/I56590836"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Jing Xu","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute, Monash University ,","Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute, Monash University, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute, Monash University ,","institution_ids":["https://openalex.org/I2799424032"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute, Monash University, Australia","institution_ids":["https://openalex.org/I2801239119","https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063409460","display_name":"Fuyi Li","orcid":"https://orcid.org/0000-0001-5216-3213"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Fuyi Li","raw_affiliation_strings":["Department of Microbiology and Immunology, the Peter Doherty Institute for Infection and Immunity, the University of Melbourne ,","Department of Microbiology and Immunology, the Peter Doherty Institute for Infection and Immunity, the University of Melbourne, Australia"],"raw_orcid":"https://orcid.org/0000-0001-5216-3213","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, the Peter Doherty Institute for Infection and Immunity, the University of Melbourne ,","institution_ids":["https://openalex.org/I4210105123"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, the Peter Doherty Institute for Infection and Immunity, the University of Melbourne, Australia","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I4210105123"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042438246","display_name":"Andr\u00e9 Leier","orcid":"https://orcid.org/0000-0002-2647-2693"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andr\u00e9 Leier","raw_affiliation_strings":["Department of Genetics, UAB School of Medicine ,","Department of Genetics, UAB School of Medicine, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, UAB School of Medicine ,","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"Department of Genetics, UAB School of Medicine, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056151279","display_name":"Dongxu Xiang","orcid":"https://orcid.org/0000-0002-2937-2786"},"institutions":[{"id":"https://openalex.org/I2799424032","display_name":"Discovery Institute","ror":"https://ror.org/05t8s3y29","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2799424032"]},{"id":"https://openalex.org/I2801239119","display_name":"Australian Regenerative Medicine Institute","ror":"https://ror.org/02qa5kg76","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801037857","https://openalex.org/I2801239119","https://openalex.org/I56590836"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Dongxu Xiang","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute, Monash University ,","Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute, Monash University, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute, Monash University ,","institution_ids":["https://openalex.org/I2799424032"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute, Monash University, Australia","institution_ids":["https://openalex.org/I2801239119","https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091565448","display_name":"Hsin\u2010Hui Shen","orcid":"https://orcid.org/0000-0002-8541-4370"},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Hsin-Hui Shen","raw_affiliation_strings":["Department of Biochemistry & Molecular Biology and Department of Materials Science & Engineering, Monash University ,","Department of Biochemistry & Molecular Biology and Department of Materials Science & Engineering, Monash University, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry & Molecular Biology and Department of Materials Science & Engineering, Monash University ,","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Department of Biochemistry & Molecular Biology and Department of Materials Science & Engineering, Monash University, Australia","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018521338","display_name":"Tatiana T Marquez Lago","orcid":null},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tatiana T Marquez Lago","raw_affiliation_strings":["Departments of Genetics and Microbiology, UAB School of Medicine ,","Departments of Genetics and Microbiology, UAB School of Medicine, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Genetics and Microbiology, UAB School of Medicine ,","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"Departments of Genetics and Microbiology, UAB School of Medicine, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100402427","display_name":"Jian Li","orcid":"https://orcid.org/0000-0001-7953-8230"},"institutions":[{"id":"https://openalex.org/I2799424032","display_name":"Discovery Institute","ror":"https://ror.org/05t8s3y29","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2799424032"]},{"id":"https://openalex.org/I2801239119","display_name":"Australian Regenerative Medicine Institute","ror":"https://ror.org/02qa5kg76","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801037857","https://openalex.org/I2801239119","https://openalex.org/I56590836"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Jian Li","raw_affiliation_strings":["Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University ,","Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University ,","institution_ids":["https://openalex.org/I2799424032"]},{"raw_affiliation_string":"Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Australia","institution_ids":["https://openalex.org/I2801239119","https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008960436","display_name":"Dong\u2010Jun Yu","orcid":"https://orcid.org/0000-0002-6786-8053"},"institutions":[{"id":"https://openalex.org/I36399199","display_name":"Nanjing University of Science and Technology","ror":"https://ror.org/00xp9wg62","country_code":"CN","type":"education","lineage":["https://openalex.org/I36399199"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dong-Jun Yu","raw_affiliation_strings":["School of Computer Science and Engineering, Nanjing University of Science and Technology ,","School of Computer Science and Engineering, Nanjing University of Science and Technology, China"],"raw_orcid":"https://orcid.org/0000-0002-6786-8053","affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Nanjing University of Science and Technology ,","institution_ids":["https://openalex.org/I36399199"]},{"raw_affiliation_string":"School of Computer Science and Engineering, Nanjing University of Science and Technology, China","institution_ids":["https://openalex.org/I36399199"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012709797","display_name":"Jiangning Song","orcid":"https://orcid.org/0000-0001-8031-9086"},"institutions":[{"id":"https://openalex.org/I2799424032","display_name":"Discovery Institute","ror":"https://ror.org/05t8s3y29","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2799424032"]},{"id":"https://openalex.org/I2801239119","display_name":"Australian Regenerative Medicine Institute","ror":"https://ror.org/02qa5kg76","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801037857","https://openalex.org/I2801239119","https://openalex.org/I56590836"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU","US"],"is_corresponding":true,"raw_author_name":"Jiangning Song","raw_affiliation_strings":["Monash Biomedicine Discovery Institute, Monash University ,","Monash Biomedicine Discovery Institute, Monash University, Australia"],"raw_orcid":"https://orcid.org/0000-0001-8031-9086","affiliations":[{"raw_affiliation_string":"Monash Biomedicine Discovery Institute, Monash University ,","institution_ids":["https://openalex.org/I2799424032"]},{"raw_affiliation_string":"Monash Biomedicine Discovery Institute, Monash University, Australia","institution_ids":["https://openalex.org/I2801239119","https://openalex.org/I56590836"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5008960436","https://openalex.org/A5012709797"],"corresponding_institution_ids":["https://openalex.org/I2799424032","https://openalex.org/I2801239119","https://openalex.org/I36399199","https://openalex.org/I56590836"],"apc_list":{"value":3894,"currency":"USD","value_usd":3894},"apc_paid":null,"fwci":14.1022,"has_fulltext":false,"cited_by_count":164,"citation_normalized_percentile":{"value":0.99440653,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"22","issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.7545089721679688},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7498934864997864},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6884682178497314},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.6758548617362976},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.5894789099693298},{"id":"https://openalex.org/keywords/test-set","display_name":"Test set","score":0.5480454564094543},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5209870934486389},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5074781775474548},{"id":"https://openalex.org/keywords/boosting","display_name":"Boosting (machine learning)","score":0.4837243854999542},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.47994735836982727},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.46017423272132874},{"id":"https://openalex.org/keywords/construct","display_name":"Construct (python library)","score":0.4437270760536194},{"id":"https://openalex.org/keywords/gradient-boosting","display_name":"Gradient boosting","score":0.4417496919631958},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.37870141863822937}],"concepts":[{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.7545089721679688},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7498934864997864},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6884682178497314},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.6758548617362976},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.5894789099693298},{"id":"https://openalex.org/C169903167","wikidata":"https://www.wikidata.org/wiki/Q3985153","display_name":"Test set","level":2,"score":0.5480454564094543},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5209870934486389},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5074781775474548},{"id":"https://openalex.org/C46686674","wikidata":"https://www.wikidata.org/wiki/Q466303","display_name":"Boosting (machine learning)","level":2,"score":0.4837243854999542},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.47994735836982727},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.46017423272132874},{"id":"https://openalex.org/C2780801425","wikidata":"https://www.wikidata.org/wiki/Q5164392","display_name":"Construct (python library)","level":2,"score":0.4437270760536194},{"id":"https://openalex.org/C70153297","wikidata":"https://www.wikidata.org/wiki/Q5591907","display_name":"Gradient boosting","level":3,"score":0.4417496919631958},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.37870141863822937},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbab083","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbab083","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33774670","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33774670","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":"Journal Article"},{"id":"pmh:oai:digital.library.adelaide.edu.au:2440/139564","is_oa":false,"landing_page_url":"https://hdl.handle.net/2440/139564","pdf_url":null,"source":{"id":"https://openalex.org/S4306401835","display_name":"Adelaide Research & Scholarship (AR&S) (University of Adelaide)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I5681781","host_organization_name":"The University of Adelaide","host_organization_lineage":["https://openalex.org/I5681781"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://dx.doi.org/10.1093/bib/bbab083","raw_type":"Journal article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15","score":0.6000000238418579}],"awards":[{"id":"https://openalex.org/G1127919792","display_name":"Stochastic modelling of telomere length regulation in ageing research","funder_award_id":"DP120104460","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"},{"id":"https://openalex.org/G241248248","display_name":"Characterisation of plant cysteine proteases with therapeutic potential","funder_award_id":"LP110200333","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"},{"id":"https://openalex.org/G4735795795","display_name":null,"funder_award_id":"2019-32","funder_id":"https://openalex.org/F4320335525","funder_display_name":"Institute for Chemical Research, Kyoto University"},{"id":"https://openalex.org/G7719334545","display_name":"\u9ad8\u7cbe\u5ea6\u591a\u5c3a\u5ea6\u86cb\u767d\u8d28\u6b8b\u57fa\u63a5\u89e6\u56fe\u53ca\u8ddd\u79bb\u56fe\u9884\u6d4b\u7814\u7a76","funder_award_id":"62072243","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8536730916","display_name":null,"funder_award_id":"31701142","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8628717564","display_name":null,"funder_award_id":"2018-28","funder_id":"https://openalex.org/F4320335525","funder_display_name":"Institute for Chemical Research, Kyoto University"},{"id":"https://openalex.org/G8879126380","display_name":"\u5927\u89c4\u6a21\u591a\u6e90\u5f02\u8d28\u86cb\u767d\u8d28\u6570\u636e\u6316\u6398\u4e2d\u7684\u82e5\u5e72\u5173\u952e\u95ee\u9898\u7814\u7a76","funder_award_id":"61772273","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8910421836","display_name":null,"funder_award_id":"R01 HD102690","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334704","display_name":"Australian Research Council","ror":"https://ror.org/05mmh0f86"},{"id":"https://openalex.org/F4320335525","display_name":"Institute for Chemical Research, Kyoto University","ror":"https://ror.org/0349bbg69"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":134,"referenced_works":["https://openalex.org/W19034019","https://openalex.org/W98799986","https://openalex.org/W273955616","https://openalex.org/W1494484168","https://openalex.org/W1515226261","https://openalex.org/W1577818368","https://openalex.org/W1578884036","https://openalex.org/W1599816078","https://openalex.org/W1817561967","https://openalex.org/W1963606380","https://openalex.org/W1964467472","https://openalex.org/W1964557084","https://openalex.org/W1973714307","https://openalex.org/W1975304761","https://openalex.org/W1976178947","https://openalex.org/W1977375188","https://openalex.org/W1977429680","https://openalex.org/W1978444624","https://openalex.org/W1981976602","https://openalex.org/W1984794455","https://openalex.org/W1989998611","https://openalex.org/W1991476392","https://openalex.org/W1998064689","https://openalex.org/W2003897459","https://openalex.org/W2015490529","https://openalex.org/W2015770408","https://openalex.org/W2016508965","https://openalex.org/W2027731040","https://openalex.org/W2027839322","https://openalex.org/W2035832348","https://openalex.org/W2040072657","https://openalex.org/W2040895929","https://openalex.org/W2043978551","https://openalex.org/W2045716015","https://openalex.org/W2047672715","https://openalex.org/W2051840895","https://openalex.org/W2054602599","https://openalex.org/W2055043387","https://openalex.org/W2055752079","https://openalex.org/W2059764020","https://openalex.org/W2063345857","https://openalex.org/W2063375278","https://openalex.org/W2064675550","https://openalex.org/W2067402644","https://openalex.org/W2077770566","https://openalex.org/W2084951281","https://openalex.org/W2100965251","https://openalex.org/W2108995755","https://openalex.org/W2110251730","https://openalex.org/W2115434912","https://openalex.org/W2128495797","https://openalex.org/W2129115651","https://openalex.org/W2131774270","https://openalex.org/W2132292391","https://openalex.org/W2133425057","https://openalex.org/W2133990480","https://openalex.org/W2142635246","https://openalex.org/W2143381319","https://openalex.org/W2144354855","https://openalex.org/W2145957695","https://openalex.org/W2146241755","https://openalex.org/W2147533449","https://openalex.org/W2148143831","https://openalex.org/W2149706766","https://openalex.org/W2150046657","https://openalex.org/W2151831732","https://openalex.org/W2152380569","https://openalex.org/W2154053567","https://openalex.org/W2156125289","https://openalex.org/W2160257187","https://openalex.org/W2163316049","https://openalex.org/W2170747616","https://openalex.org/W2175270296","https://openalex.org/W2295598076","https://openalex.org/W2339719866","https://openalex.org/W2342937250","https://openalex.org/W2374370833","https://openalex.org/W2511835277","https://openalex.org/W2513786151","https://openalex.org/W2518034873","https://openalex.org/W2537930570","https://openalex.org/W2588463038","https://openalex.org/W2588467130","https://openalex.org/W2595741664","https://openalex.org/W2622581388","https://openalex.org/W2769518858","https://openalex.org/W2772266296","https://openalex.org/W2774504456","https://openalex.org/W2791848964","https://openalex.org/W2793168264","https://openalex.org/W2806146459","https://openalex.org/W2807001312","https://openalex.org/W2890201337","https://openalex.org/W2899123765","https://openalex.org/W2899153547","https://openalex.org/W2911964244","https://openalex.org/W2913961829","https://openalex.org/W2917874934","https://openalex.org/W2936599975","https://openalex.org/W2946682182","https://openalex.org/W2948272581","https://openalex.org/W2964182903","https://openalex.org/W2965128681","https://openalex.org/W2967960129","https://openalex.org/W2978223337","https://openalex.org/W2984592028","https://openalex.org/W2991176535","https://openalex.org/W2998197489","https://openalex.org/W3003306158","https://openalex.org/W3004000061","https://openalex.org/W3025501158","https://openalex.org/W3036144909","https://openalex.org/W3043115370","https://openalex.org/W3046868072","https://openalex.org/W3047705148","https://openalex.org/W3080137602","https://openalex.org/W3087692915","https://openalex.org/W3094567318","https://openalex.org/W3094708881","https://openalex.org/W3102476541","https://openalex.org/W3152218910","https://openalex.org/W4210700827","https://openalex.org/W4232737019","https://openalex.org/W4236137412","https://openalex.org/W4239619560","https://openalex.org/W6610017368","https://openalex.org/W6630786662","https://openalex.org/W6634609459","https://openalex.org/W6667333778","https://openalex.org/W6703930214","https://openalex.org/W6756092659","https://openalex.org/W6759104856","https://openalex.org/W6766522092","https://openalex.org/W7075598231"],"related_works":["https://openalex.org/W2967733078","https://openalex.org/W3204430031","https://openalex.org/W3137904399","https://openalex.org/W4310492845","https://openalex.org/W2885778889","https://openalex.org/W4310224730","https://openalex.org/W2766514146","https://openalex.org/W4386690025","https://openalex.org/W4289703016","https://openalex.org/W2885516856"],"abstract_inverted_index":{"Antimicrobial":[0],"peptides":[1],"(AMPs)":[2],"are":[3,189,243],"a":[4,13,17,101,105],"unique":[5],"and":[6,22,95,113,142,159,179,229,242],"diverse":[7],"group":[8],"of":[9,19,48,57,74,107,128,247,249],"molecules":[10],"that":[11,172,223],"play":[12],"crucial":[14],"role":[15],"in":[16,31,81],"myriad":[18],"biological":[20],"processes":[21],"cellular":[23],"functions.":[24],"AMP-related":[25],"studies":[26],"have":[27,68],"become":[28],"increasingly":[29],"popular":[30],"recent":[32],"years":[33],"due":[34,53],"to":[35,54,207],"antimicrobial":[36],"resistance,":[37],"which":[38],"is":[39],"becoming":[40],"an":[41,134],"emerging":[42],"global":[43],"concern.":[44],"Systematic":[45],"experimental":[46],"identification":[47,112],"AMPs":[49,141],"faces":[50],"many":[51],"difficulties":[52],"the":[55,116,125,129,175,181,186,192,203,215,245],"limitations":[56],"current":[58,108],"methods.":[59,120,184],"Given":[60],"its":[61],"significance,":[62],"more":[63],"than":[64,237],"30":[65],"computational":[66,162],"methods":[67,163,213,241],"been":[69],"developed":[70],"for":[71,110],"accurate":[72],"prediction":[73,252],"AMPs.":[75],"These":[76,219],"approaches":[77,109],"show":[78],"high":[79],"diversity":[80],"their":[82],"data":[83,86,137,150,167,194,217],"set":[84,138],"size,":[85],"quality,":[87],"core":[88],"algorithms,":[89],"feature":[90,92],"extraction,":[91],"selection":[93],"techniques":[94],"evaluation":[96],"strategies.":[97],"Here,":[98],"we":[99,123,146,200],"provide":[100],"comprehensive":[102],"survey":[103],"on":[104,133,153,165,214],"variety":[106],"AMP":[111,157,251],"point":[114],"at":[115],"differences":[117],"between":[118],"these":[119,166],"In":[121],"addition,":[122],"evaluate":[124],"predictive":[126,177,187],"performance":[127,178],"surveyed":[130],"tools":[131],"based":[132,152,164],"independent":[135],"test":[136,206],"containing":[139],"1536":[140,143],"non-AMPs.":[144],"Furthermore,":[145],"construct":[147],"six":[148,154],"validation":[149],"sets":[151,195],"different":[155,161,193,198,209],"common":[156],"databases":[158],"compare":[160],"sets.":[168],"The":[169],"results":[170,221],"indicate":[171,222],"amPEPpy":[173],"achieves":[174],"best":[176],"outperforms":[180],"other":[182,238],"compared":[183],"As":[185],"performances":[188,236],"affected":[190],"by":[191,197],"used":[196],"methods,":[199],"additionally":[201],"perform":[202],"5-fold":[204],"cross-validation":[205,220],"benchmark":[208],"traditional":[210],"machine":[211,228,239],"learning":[212,240],"same":[216],"set.":[218],"random":[224],"forest,":[225],"support":[226],"vector":[227],"eXtreme":[230],"Gradient":[231],"Boosting":[232],"achieve":[233],"comparatively":[234],"better":[235],"often":[244],"algorithms":[246],"choice":[248],"multiple":[250],"tools.":[253]},"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":38},{"year":2024,"cited_by_count":46},{"year":2023,"cited_by_count":30},{"year":2022,"cited_by_count":23},{"year":2021,"cited_by_count":7}],"updated_date":"2026-08-29T07:29:34.045763","created_date":"2025-10-10T00:00:00"}