{"id":"https://openalex.org/W2980987121","doi":"https://doi.org/10.1093/nar/gkz916","title":"PADS Arsenal: a database of prokaryotic defense systems related genes","display_name":"PADS Arsenal: a database of prokaryotic defense systems related genes","publication_year":2019,"publication_date":"2019-10-04","ids":{"openalex":"https://openalex.org/W2980987121","doi":"https://doi.org/10.1093/nar/gkz916","mag":"2980987121","pmid":"https://pubmed.ncbi.nlm.nih.gov/31620779"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkz916","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkz916","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/nar/gkz916","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100330174","display_name":"Yadong Zhang","orcid":"https://orcid.org/0000-0003-0918-5673"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yadong Zhang","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China","National Genomics Data Center, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"National Genomics Data Center, Beijing 100101, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101549724","display_name":"Zhewen Zhang","orcid":"https://orcid.org/0000-0002-9422-822X"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]}],"countries":["CA","CN"],"is_corresponding":false,"raw_author_name":"Zhewen Zhang","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","National Genomics Data Center, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"National Genomics Data Center, Beijing 100101, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101549724","display_name":"Zhewen Zhang","orcid":"https://orcid.org/0000-0002-9422-822X"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CA","CN"],"is_corresponding":true,"raw_author_name":"Zhewen Zhang","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","National Genomics Data Center, Beijing 100101, China","College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"National Genomics Data Center, Beijing 100101, China","institution_ids":[]},{"raw_affiliation_string":"College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100397064","display_name":"Hao Zhang","orcid":"https://orcid.org/0000-0003-4093-5647"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Hao Zhang","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China","National Genomics Data Center, Beijing 100101, China","Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"National Genomics Data Center, Beijing 100101, China","institution_ids":[]},{"raw_affiliation_string":"Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042127372","display_name":"Yongbing Zhao","orcid":"https://orcid.org/0000-0002-9917-7425"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Yongbing Zhao","raw_affiliation_strings":["Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL 32224, USA","Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710"]},{"raw_affiliation_string":"Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007855766","display_name":"Zaichao Zhang","orcid":"https://orcid.org/0000-0001-8985-8094"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CA","CN"],"is_corresponding":false,"raw_author_name":"Zaichao Zhang","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","National Genomics Data Center, Beijing 100101, China","College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"National Genomics Data Center, Beijing 100101, China","institution_ids":[]},{"raw_affiliation_string":"College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007855766","display_name":"Zaichao Zhang","orcid":"https://orcid.org/0000-0001-8985-8094"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]}],"countries":["CA","CN"],"is_corresponding":true,"raw_author_name":"Zaichao Zhang","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","National Genomics Data Center, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Department of Biology, The University of Western Ontario, London, Ontario N6A 5B7, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"National Genomics Data Center, Beijing 100101, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009289581","display_name":"Jingfa Xiao","orcid":"https://orcid.org/0000-0002-2835-4340"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jingfa Xiao","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China","National Genomics Data Center, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"National Genomics Data Center, Beijing 100101, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5007855766","https://openalex.org/A5009289581","https://openalex.org/A5101549724"],"corresponding_institution_ids":["https://openalex.org/I125749732","https://openalex.org/I19820366","https://openalex.org/I2801577699","https://openalex.org/I4210165038"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":4.3801,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.95514357,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"48","issue":"D1","first_page":"D590","last_page":"D598"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8003368377685547},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.6614363193511963},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.6065951585769653},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5923384428024292},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5247811675071716},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.5176154375076294},{"id":"https://openalex.org/keywords/archaea","display_name":"Archaea","score":0.4940550625324249},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.37233269214630127},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3264031410217285},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.1842939257621765}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8003368377685547},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6614363193511963},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.6065951585769653},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5923384428024292},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5247811675071716},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5176154375076294},{"id":"https://openalex.org/C550995028","wikidata":"https://www.wikidata.org/wiki/Q10872","display_name":"Archaea","level":3,"score":0.4940550625324249},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.37233269214630127},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3264031410217285},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1842939257621765}],"mesh":[{"descriptor_ui":"D001105","descriptor_name":"Archaea","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001105","descriptor_name":"Archaea","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001105","descriptor_name":"Archaea","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001105","descriptor_name":"Archaea","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001105","descriptor_name":"Archaea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001105","descriptor_name":"Archaea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001105","descriptor_name":"Archaea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001105","descriptor_name":"Archaea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D001435","descriptor_name":"Bacteriophages","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D001435","descriptor_name":"Bacteriophages","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D001435","descriptor_name":"Bacteriophages","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D001435","descriptor_name":"Bacteriophages","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015280","descriptor_name":"DNA Restriction-Modification Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015280","descriptor_name":"DNA Restriction-Modification Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015280","descriptor_name":"DNA Restriction-Modification Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015280","descriptor_name":"DNA Restriction-Modification Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023641","descriptor_name":"Archaeal Viruses","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D023641","descriptor_name":"Archaeal Viruses","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D023641","descriptor_name":"Archaeal Viruses","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D023641","descriptor_name":"Archaeal Viruses","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkz916","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkz916","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:31620779","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31620779","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7145686","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7145686","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkz916","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkz916","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1250020617","display_name":null,"funder_award_id":"XXH13505-05","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"},{"id":"https://openalex.org/G1904268823","display_name":null,"funder_award_id":"153F11KYSB20160008","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"},{"id":"https://openalex.org/G2518751491","display_name":null,"funder_award_id":"31970634","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3422691529","display_name":null,"funder_award_id":"31771465","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8714624460","display_name":null,"funder_award_id":"2016-999999-65-01-000696-07","funder_id":"https://openalex.org/F4320326446","funder_display_name":"National Development and Reform Commission"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321133","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35"},{"id":"https://openalex.org/F4320326446","display_name":"National Development and Reform Commission","ror":"https://ror.org/017a59b72"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W1604915411","https://openalex.org/W1968305507","https://openalex.org/W1972708645","https://openalex.org/W1976391205","https://openalex.org/W1978094899","https://openalex.org/W1981382847","https://openalex.org/W1986823214","https://openalex.org/W2000541324","https://openalex.org/W2000887650","https://openalex.org/W2004926532","https://openalex.org/W2013042266","https://openalex.org/W2013568105","https://openalex.org/W2016315684","https://openalex.org/W2017721099","https://openalex.org/W2033718613","https://openalex.org/W2034120175","https://openalex.org/W2038482997","https://openalex.org/W2047032063","https://openalex.org/W2048125480","https://openalex.org/W2060573994","https://openalex.org/W2064815984","https://openalex.org/W2068056297","https://openalex.org/W2095624846","https://openalex.org/W2096093282","https://openalex.org/W2096525273","https://openalex.org/W2105364540","https://openalex.org/W2107644675","https://openalex.org/W2109867978","https://openalex.org/W2111211467","https://openalex.org/W2122492159","https://openalex.org/W2122673596","https://openalex.org/W2124363431","https://openalex.org/W2127774996","https://openalex.org/W2131730777","https://openalex.org/W2133620956","https://openalex.org/W2136632285","https://openalex.org/W2143592941","https://openalex.org/W2145250129","https://openalex.org/W2150182573","https://openalex.org/W2156738105","https://openalex.org/W2158605421","https://openalex.org/W2158714788","https://openalex.org/W2163241233","https://openalex.org/W2197954767","https://openalex.org/W2298249827","https://openalex.org/W2324821431","https://openalex.org/W2406250479","https://openalex.org/W2466387107","https://openalex.org/W2587588342","https://openalex.org/W2602907179","https://openalex.org/W2605016113","https://openalex.org/W2738980776","https://openalex.org/W2766750388","https://openalex.org/W2767051074","https://openalex.org/W2784532673","https://openalex.org/W2803245377","https://openalex.org/W2883315617","https://openalex.org/W2898402099","https://openalex.org/W2916654259","https://openalex.org/W4210974853","https://openalex.org/W4239634997","https://openalex.org/W4246016408","https://openalex.org/W4247447075","https://openalex.org/W4297084841"],"related_works":["https://openalex.org/W1607298653","https://openalex.org/W4240162843","https://openalex.org/W2361861616","https://openalex.org/W2006696969","https://openalex.org/W1510349474","https://openalex.org/W2142984901","https://openalex.org/W150190154","https://openalex.org/W2263699433","https://openalex.org/W4253855002","https://openalex.org/W2377979023"],"abstract_inverted_index":{"Defense":[0],"systems":[1,37,47,124],"are":[2,21],"vital":[3],"weapons":[4],"for":[5],"prokaryotes":[6],"to":[7,49,73,121,145,178],"resist":[8],"heterologous":[9],"DNA":[10],"and":[11,19,27,77,114,128,148],"survive":[12],"from":[13,105,166],"the":[14,61,97,159,180],"constant":[15],"invasion":[16],"of":[17,35,86,93,99,112,151,163,182],"viruses,":[18],"they":[20],"widely":[22],"used":[23],"in":[24],"biochemistry":[25],"investigation":[26],"antimicrobial":[28],"drug":[29],"research.":[30],"So":[31],"far,":[32],"numerous":[33],"types":[34],"defense":[36,46,52,64,80,94,123,152,164,184],"have":[38],"been":[39],"discovered,":[40],"but":[41],"there":[42],"is":[43,140,172],"no":[44],"comprehensive":[45,176],"database":[48,71],"organize":[50],"prokaryotic":[51,62,79,183],"gene":[53,81],"datasets.":[54,82],"To":[55],"fill":[56],"this":[57],"gap,":[58],"we":[59],"unveil":[60],"antiviral":[63],"system":[65,95],"(PADS)":[66],"Arsenal":[67,88,117,144,155,171],"(https://bigd.big.ac.cn/padsarsenal),":[68],"a":[69,173],"public":[70],"dedicated":[72],"gathering,":[74],"storing,":[75],"analyzing":[76],"visualizing":[78],"The":[83],"initial":[84],"version":[85],"PADS":[87,116,143,154,170],"integrates":[89],"18":[90],"distinctive":[91],"categories":[92],"with":[96,131],"annotation":[98,147],"6":[100],"600":[101],"264":[102],"genes":[103,126,165],"retrieved":[104],"63,701":[106],"genomes":[107],"across":[108],"33":[109],"390":[110],"species":[111],"archaea":[113],"bacteria.":[115],"provides":[118],"various":[119],"ways":[120],"retrieve":[122],"related":[125],"information":[127,162],"visualize":[129,158],"them":[130],"multifarious":[132],"function":[133],"modes.":[134],"Moreover,":[135],"an":[136],"online":[137],"analysis":[138,150],"pipeline":[139],"integrated":[141],"into":[142],"facilitate":[146],"evolutionary":[149],"genes.":[153],"can":[156],"also":[157],"dynamic":[160],"variation":[161],"pan-genome":[167],"analysis.":[168],"Overall,":[169],"state-of-the-art":[174],"open":[175],"resource":[177],"accelerate":[179],"research":[181],"systems.":[185]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":37},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-04-06T07:47:59.780226","created_date":"2025-10-10T00:00:00"}