{"id":"https://openalex.org/W4243979784","doi":"https://doi.org/10.1093/nar/gky973","title":"CORUM: the comprehensive resource of mammalian protein complexes\u20142019","display_name":"CORUM: the comprehensive resource of mammalian protein complexes\u20142019","publication_year":2018,"publication_date":"2018-10-18","ids":{"openalex":"https://openalex.org/W4243979784","doi":"https://doi.org/10.1093/nar/gky973"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gky973","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gky973","pdf_url":"https://academic.oup.com/nar/article-pdf/47/D1/D559/27436111/gky973.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/47/D1/D559/27436111/gky973.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089065337","display_name":"M\u0103d\u0103lina Giurgiu","orcid":"https://orcid.org/0000-0001-5007-7442"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Madalina Giurgiu","raw_affiliation_strings":["Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057110456","display_name":"Julian Reinhard","orcid":null},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julian Reinhard","raw_affiliation_strings":["Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008184926","display_name":"Barbara Brauner","orcid":null},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Barbara Brauner","raw_affiliation_strings":["Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067285673","display_name":"Irmtraud Dunger-Kaltenbach","orcid":null},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Irmtraud Dunger-Kaltenbach","raw_affiliation_strings":["Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042426510","display_name":"Gisela Fobo","orcid":null},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gisela Fobo","raw_affiliation_strings":["Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076988991","display_name":"Goar Frishman","orcid":null},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Goar Frishman","raw_affiliation_strings":["Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085214428","display_name":"Corinna Montrone","orcid":null},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Corinna Montrone","raw_affiliation_strings":["Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021607242","display_name":"Andreas Ruepp","orcid":"https://orcid.org/0000-0003-1705-3515"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Andreas Ruepp","raw_affiliation_strings":["Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":"https://orcid.org/0000-0003-1705-3515","affiliations":[{"raw_affiliation_string":"Institute for Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health (GmbH), Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5021607242"],"corresponding_institution_ids":["https://openalex.org/I3018134672"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":26.8801,"has_fulltext":false,"cited_by_count":702,"citation_normalized_percentile":{"value":0.99804385,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"47","issue":"D1","first_page":"D559","last_page":"D563"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7800462245941162},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5563225746154785},{"id":"https://openalex.org/keywords/protein-subunit","display_name":"Protein subunit","score":0.528421938419342},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.47537365555763245},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2538464069366455}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7800462245941162},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5563225746154785},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.528421938419342},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.47537365555763245},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2538464069366455}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gky973","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gky973","pdf_url":"https://academic.oup.com/nar/article-pdf/47/D1/D559/27436111/gky973.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5301959","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6323970","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:opus-zb.helmholtz-muenchen.de:54591","is_oa":true,"landing_page_url":"https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=54591","pdf_url":null,"source":{"id":"https://openalex.org/S4377196115","display_name":"Site cant be reached","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res. 47, D559-D563 (2019)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/nar/gky973","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gky973","pdf_url":"https://academic.oup.com/nar/article-pdf/47/D1/D559/27436111/gky973.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1373231889","display_name":null,"funder_award_id":"RF1AG057452","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5601253901","display_name":null,"funder_award_id":"RF1 AG057452","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1513501940","https://openalex.org/W1611787727","https://openalex.org/W1777916189","https://openalex.org/W1838945435","https://openalex.org/W2027221381","https://openalex.org/W2043764521","https://openalex.org/W2050721857","https://openalex.org/W2066180106","https://openalex.org/W2078717687","https://openalex.org/W2083207235","https://openalex.org/W2085677283","https://openalex.org/W2096465161","https://openalex.org/W2116117181","https://openalex.org/W2128900650","https://openalex.org/W2130971328","https://openalex.org/W2137986227","https://openalex.org/W2148043260","https://openalex.org/W2172119527","https://openalex.org/W2227497344","https://openalex.org/W2234151204","https://openalex.org/W2263739890","https://openalex.org/W2616561032","https://openalex.org/W2624282460","https://openalex.org/W2697722282","https://openalex.org/W2752984803","https://openalex.org/W2766916632","https://openalex.org/W2782153240","https://openalex.org/W2787788280","https://openalex.org/W2803524288","https://openalex.org/W4233120011","https://openalex.org/W4233437719","https://openalex.org/W4250359879"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W2013243191","https://openalex.org/W1971568933"],"abstract_inverted_index":{"CORUM":[0,51,72,177],"is":[1,39,74,178],"a":[2,6,94,122,147],"database":[3],"that":[4],"provides":[5],"manually":[7],"curated":[8],"repository":[9],"of":[10,30,44,67,82,111,116,134,140,149,167],"experimentally":[11],"characterized":[12],"protein":[13,56,69,84,95,138,151,170],"complexes":[14,57,90,139,152],"from":[15,76],"mammalian":[16,68],"organisms,":[17],"mainly":[18],"human":[19],"(67%),":[20],"mouse":[21],"(15%)":[22],"and":[23,36,46,61],"rat":[24],"(10%).":[25],"Given":[26],"the":[27,59,83,105,132],"vital":[28],"functions":[29,101,163],"these":[31],"macromolecular":[32],"machines,":[33],"their":[34],"identification":[35],"functional":[37],"characterization":[38],"foundational":[40],"to":[41,160],"our":[42],"understanding":[43],"normal":[45],"disease":[47],"biology.":[48],"The":[49,71],"new":[50],"3.0":[52],"release":[53],"encompasses":[54],"4274":[55],"offering":[58],"largest":[60],"most":[62],"comprehensive":[63],"publicly":[64],"available":[65],"dataset":[66,73],"complexes.":[70],"built":[75],"4473":[77],"different":[78],"genes,":[79],"representing":[80],"22%":[81],"coding":[85],"genes":[86],"in":[87],"humans.":[88],"Protein":[89],"are":[91],"described":[92],"by":[93],"complex":[96,171],"name,":[97],"subunit":[98],"composition,":[99],"cellular":[100,162,175],"as":[102,104,165],"well":[103],"literature":[106],"references.":[107],"Information":[108],"about":[109],"stoichiometry":[110],"subunits":[112],"depends":[113],"on":[114],"availability":[115],"experimental":[117],"data.":[118],"Recent":[119],"developments":[120],"include":[121],"graphical":[123],"tool":[124],"displaying":[125],"known":[126],"interactions":[127],"between":[128],"subunits.":[129,156],"This":[130],"allows":[131],"prediction":[133],"structural":[135],"interconnections":[136],"within":[137],"unknown":[141],"structure.":[142],"In":[143],"addition,":[144],"we":[145],"present":[146],"set":[148],"58":[150],"with":[153],"alternatively":[154],"spliced":[155],"Those":[157],"were":[158],"found":[159],"affect":[161],"such":[164],"regulation":[166],"apoptotic":[168],"activity,":[169],"assembly":[172],"or":[173],"define":[174],"localization.":[176],"freely":[179],"accessible":[180],"at":[181],"http://mips.helmholtz-muenchen.de/corum/.":[182]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":51},{"year":2024,"cited_by_count":75},{"year":2023,"cited_by_count":120},{"year":2022,"cited_by_count":142},{"year":2021,"cited_by_count":158},{"year":2020,"cited_by_count":92},{"year":2019,"cited_by_count":43},{"year":2018,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}