{"id":"https://openalex.org/W2901361432","doi":"https://doi.org/10.1093/nar/gky1047","title":"The MemProtMD database: a resource for membrane-embedded protein structures and their lipid interactions","display_name":"The MemProtMD database: a resource for membrane-embedded protein structures and their lipid interactions","publication_year":2018,"publication_date":"2018-10-16","ids":{"openalex":"https://openalex.org/W2901361432","doi":"https://doi.org/10.1093/nar/gky1047","mag":"2901361432","pmid":"https://pubmed.ncbi.nlm.nih.gov/30418645"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gky1047","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gky1047","pdf_url":"https://academic.oup.com/nar/article-pdf/47/D1/D390/27437085/gky1047.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/47/D1/D390/27437085/gky1047.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050679135","display_name":"Thomas D. Newport","orcid":null},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Thomas D Newport","raw_affiliation_strings":["Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041718990","display_name":"Mark S.P. Sansom","orcid":"https://orcid.org/0000-0001-6360-7959"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark S\u00a0P Sansom","raw_affiliation_strings":["Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051819492","display_name":"Phillip J. Stansfeld","orcid":"https://orcid.org/0000-0001-8800-7669"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Phillip J Stansfeld","raw_affiliation_strings":["Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051819492"],"corresponding_institution_ids":["https://openalex.org/I40120149"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":1653,"currency":"EUR","value_usd":1782},"fwci":6.5092,"has_fulltext":true,"cited_by_count":228,"citation_normalized_percentile":{"value":0.97796561,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"47","issue":"D1","first_page":"D390","last_page":"D397"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13127","display_name":"Biotin and Related Studies","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uniprot","display_name":"UniProt","score":0.8187031149864197},{"id":"https://openalex.org/keywords/protein-data-bank","display_name":"Protein Data Bank (RCSB PDB)","score":0.8150850534439087},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6349059343338013},{"id":"https://openalex.org/keywords/protein-data-bank","display_name":"Protein Data Bank","score":0.610715389251709},{"id":"https://openalex.org/keywords/membrane-protein","display_name":"Membrane protein","score":0.6060242652893066},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.5473889112472534},{"id":"https://openalex.org/keywords/lipid-bilayer","display_name":"Lipid bilayer","score":0.5172320008277893},{"id":"https://openalex.org/keywords/integral-membrane-protein","display_name":"Integral membrane protein","score":0.4789339005947113},{"id":"https://openalex.org/keywords/online-database","display_name":"Online database","score":0.4108661413192749},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.362216055393219},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.3575434386730194},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3455043435096741},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2523318827152252},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.21451351046562195},{"id":"https://openalex.org/keywords/membrane","display_name":"Membrane","score":0.17613717913627625},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.14284193515777588}],"concepts":[{"id":"https://openalex.org/C202264299","wikidata":"https://www.wikidata.org/wiki/Q905695","display_name":"UniProt","level":3,"score":0.8187031149864197},{"id":"https://openalex.org/C65556437","wikidata":"https://www.wikidata.org/wiki/Q766195","display_name":"Protein Data Bank (RCSB PDB)","level":2,"score":0.8150850534439087},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6349059343338013},{"id":"https://openalex.org/C119145174","wikidata":"https://www.wikidata.org/wiki/Q7251429","display_name":"Protein Data Bank","level":3,"score":0.610715389251709},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.6060242652893066},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.5473889112472534},{"id":"https://openalex.org/C39944091","wikidata":"https://www.wikidata.org/wiki/Q423279","display_name":"Lipid bilayer","level":3,"score":0.5172320008277893},{"id":"https://openalex.org/C161200384","wikidata":"https://www.wikidata.org/wiki/Q1757382","display_name":"Integral membrane protein","level":4,"score":0.4789339005947113},{"id":"https://openalex.org/C2777715827","wikidata":"https://www.wikidata.org/wiki/Q7094076","display_name":"Online database","level":2,"score":0.4108661413192749},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.362216055393219},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.3575434386730194},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3455043435096741},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2523318827152252},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.21451351046562195},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.17613717913627625},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14284193515777588}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008051","descriptor_name":"Lipid Bilayers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008051","descriptor_name":"Lipid Bilayers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008051","descriptor_name":"Lipid Bilayers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008051","descriptor_name":"Lipid Bilayers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008563","descriptor_name":"Membrane Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008563","descriptor_name":"Membrane Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008563","descriptor_name":"Membrane Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008563","descriptor_name":"Membrane Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1093/nar/gky1047","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gky1047","pdf_url":"https://academic.oup.com/nar/article-pdf/47/D1/D390/27437085/gky1047.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:30418645","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30418645","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:wrap.warwick.ac.uk:126675","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306400665","display_name":"Warwick Research Archive Portal (University of Warwick)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39555362","host_organization_name":"University of Warwick","host_organization_lineage":["https://openalex.org/I39555362"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5302028","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6324062","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:ora.ox.ac.uk:uuid:e095225b-67e0-4124-b652-96a637a98796","is_oa":true,"landing_page_url":"https://ora.ox.ac.uk/objects/uuid:e095225b-67e0-4124-b652-96a637a98796","pdf_url":null,"source":{"id":"https://openalex.org/S4306402636","display_name":"Oxford University Research Archive (ORA) (University of Oxford)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I40120149","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/I40120149"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6324062","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6324062","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gky1047","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gky1047","pdf_url":"https://academic.oup.com/nar/article-pdf/47/D1/D390/27437085/gky1047.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1015763213","display_name":null,"funder_award_id":"BB/L01386X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G1029219657","display_name":null,"funder_award_id":"1274908","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G1502084111","display_name":null,"funder_award_id":"EP/J010421/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G1556072413","display_name":"Computational tools for enzyme engineering: bridging the gap between enzymologists and expert simulation","funder_award_id":"BB/L018756/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G1592560434","display_name":null,"funder_award_id":"EP/G042853/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G1717999737","display_name":null,"funder_award_id":"BB/L018756/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G1954672288","display_name":"BrisSynBio: Bristol Centre for Synthetic Biology","funder_award_id":"BB/L01386X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G2083660927","display_name":null,"funder_award_id":"208361/Z/17/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G2087520253","display_name":null,"funder_award_id":"EP/R029407/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G217339099","display_name":"CCP-BioSim: Biomolecular simulation at the life sciences interface","funder_award_id":"EP/J010421/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G2467146873","display_name":"Inquire: Software for real-time analysis of binding","funder_award_id":"BB/K016601/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G271256356","display_name":null,"funder_award_id":"EP/E022197/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3061614889","display_name":null,"funder_award_id":"BB/R002517/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G339059223","display_name":null,"funder_award_id":"Z/17/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G3390685744","display_name":"The UK High-End Computing Consortium for Biomolecular Simulation","funder_award_id":"EP/R029407/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3583580618","display_name":null,"funder_award_id":"BB/K016601/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G3889144934","display_name":null,"funder_award_id":"EP/G002843/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G4298129422","display_name":"Assembly and Dynamics of Bacterial Chemosensory Signaling Arrays","funder_award_id":"BB/S003339/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G4441579171","display_name":null,"funder_award_id":"EP/N024117/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G4706702539","display_name":"CCP-BioSim: Biomolecular Simulation at the Life Sciences Interface","funder_award_id":"EP/M022609/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G4727989359","display_name":"CCP-BioSim: Biomolecular simulation at the life sciences interface","funder_award_id":"EP/J010588/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G4799187780","display_name":null,"funder_award_id":"GR/R86119/01","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G4873943010","display_name":"The Lipoprotein Biogenesis Pathway: An Emerging Structural Target for Novel Antibiotics","funder_award_id":"BB/P01948X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G4995811072","display_name":null,"funder_award_id":"BB/R00126X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G504678512","display_name":null,"funder_award_id":"BB/L002558/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G5066350998","display_name":null,"funder_award_id":"P01948X","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G507154275","display_name":null,"funder_award_id":"BB/P01948X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G5192625861","display_name":null,"funder_award_id":"EP/M015378/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G5325165597","display_name":null,"funder_award_id":"1364172","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G535146685","display_name":"Combined experimental and computational investigations of a nucleophilic displacement reaction with a hydride leaving group","funder_award_id":"EP/G002843/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G563806405","display_name":null,"funder_award_id":"BB/S003339/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G5758995618","display_name":null,"funder_award_id":"EP/M022609/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6148688325","display_name":null,"funder_award_id":"EP/M027546/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6504168431","display_name":"Adaptive Multi-Resolution Massively-Multicore Hybrid Dynamics","funder_award_id":"EP/I030395/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6515148465","display_name":"Combined quantum mechanics/molecular mechanics (QM/MM) Monte Carlo free energy simulations: a feasibility study","funder_award_id":"EP/E022197/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G658036437","display_name":"Predicting drug-target binding kinetics through multiscale simulations","funder_award_id":"EP/M015378/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6981549688","display_name":"Nicotinic Ligand Development to Target Smoking Cessation and Gain a Molecular Level Understanding of Partial Agonism","funder_award_id":"EP/N024117/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G712558274","display_name":null,"funder_award_id":"BB/I019855/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G7263767309","display_name":"Crowding and Complexity: Simulation Studies of Biologically Realistic Membrane Models","funder_award_id":"BB/L002558/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G7386727240","display_name":"BristolBridge: Bridging the Gaps between the Engineering and Physical Sciences and Antimicrobial Resistance","funder_award_id":"EP/M027546/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7613874618","display_name":"Multiscale Ensemble Computing for Modelling Biological Catalysts","funder_award_id":"EP/G042853/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7652098087","display_name":"Computational biochemistry: predictive modelling for biology and medicine","funder_award_id":"EP/G007705/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7814653466","display_name":null,"funder_award_id":"EP/I030395/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G783393384","display_name":null,"funder_award_id":"EP/J010588/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8294306494","display_name":null,"funder_award_id":"EP/G007705/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8323842324","display_name":"MemProtMD: A resource for membrane proteins","funder_award_id":"BB/I019855/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G8476502574","display_name":"The UK High-End Computing Consortium for Biomolecular Simulation","funder_award_id":"EP/L000253/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8947107902","display_name":null,"funder_award_id":"EP/L000253/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8987452242","display_name":"Nano to Meso and Back Again: Capturing and Exploiting Dynamic Heterogeneities in Biological Membranes via Large Scale Simulations","funder_award_id":"BB/R00126X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G912698033","display_name":"Functional dynamics of the KATP channel","funder_award_id":"BB/R002517/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2901361432.pdf","grobid_xml":"https://content.openalex.org/works/W2901361432.grobid-xml"},"referenced_works_count":100,"referenced_works":["https://openalex.org/W1031578623","https://openalex.org/W1493374012","https://openalex.org/W1947778485","https://openalex.org/W1971456069","https://openalex.org/W1974821195","https://openalex.org/W1978308218","https://openalex.org/W1979780089","https://openalex.org/W1996795941","https://openalex.org/W2000300989","https://openalex.org/W2029235012","https://openalex.org/W2029667189","https://openalex.org/W2031371697","https://openalex.org/W2051864856","https://openalex.org/W2052299042","https://openalex.org/W2057013716","https://openalex.org/W2057843068","https://openalex.org/W2057972192","https://openalex.org/W2059334226","https://openalex.org/W2059715478","https://openalex.org/W2062709131","https://openalex.org/W2073726493","https://openalex.org/W2080985792","https://openalex.org/W2099384461","https://openalex.org/W2104477830","https://openalex.org/W2108713843","https://openalex.org/W2108984616","https://openalex.org/W2119130600","https://openalex.org/W2125632831","https://openalex.org/W2130479394","https://openalex.org/W2132820240","https://openalex.org/W2132926880","https://openalex.org/W2140831051","https://openalex.org/W2143070723","https://openalex.org/W2144944670","https://openalex.org/W2145450694","https://openalex.org/W2147496515","https://openalex.org/W2147526198","https://openalex.org/W2148395120","https://openalex.org/W2149522618","https://openalex.org/W2151156268","https://openalex.org/W2161062388","https://openalex.org/W2162274915","https://openalex.org/W2163013798","https://openalex.org/W2164659462","https://openalex.org/W2170711116","https://openalex.org/W2171681733","https://openalex.org/W2178135303","https://openalex.org/W2206954826","https://openalex.org/W2327174080","https://openalex.org/W2510946698","https://openalex.org/W2578365017","https://openalex.org/W2609731092","https://openalex.org/W2768177014","https://openalex.org/W4211083314","https://openalex.org/W4232686413","https://openalex.org/W4243460074","https://openalex.org/W6626923867","https://openalex.org/W6629568751","https://openalex.org/W6631828510","https://openalex.org/W6640840232","https://openalex.org/W6642995253","https://openalex.org/W6645095076","https://openalex.org/W6649335528","https://openalex.org/W6650395826","https://openalex.org/W6657818778","https://openalex.org/W6657985985","https://openalex.org/W6663419101","https://openalex.org/W6663420981","https://openalex.org/W6664613738","https://openalex.org/W6664659017","https://openalex.org/W6665053521","https://openalex.org/W6665053958","https://openalex.org/W6665497691","https://openalex.org/W6666276502","https://openalex.org/W6670657633","https://openalex.org/W6676499634","https://openalex.org/W6677569475","https://openalex.org/W6678526770","https://openalex.org/W6679190015","https://openalex.org/W6679736464","https://openalex.org/W6680688628","https://openalex.org/W6681480018","https://openalex.org/W6681609863","https://openalex.org/W6681615641","https://openalex.org/W6681765588","https://openalex.org/W6682056723","https://openalex.org/W6682170587","https://openalex.org/W6683775605","https://openalex.org/W6683928384","https://openalex.org/W6684026321","https://openalex.org/W6684270820","https://openalex.org/W6684989612","https://openalex.org/W6685170586","https://openalex.org/W6685196464","https://openalex.org/W6688002869","https://openalex.org/W6725880725","https://openalex.org/W6732357105","https://openalex.org/W6737130418","https://openalex.org/W6746571443","https://openalex.org/W7074017685"],"related_works":["https://openalex.org/W3132544722","https://openalex.org/W3181892255","https://openalex.org/W4232154957","https://openalex.org/W4292058683","https://openalex.org/W2765199194","https://openalex.org/W4307362031","https://openalex.org/W2022209941","https://openalex.org/W4205671017","https://openalex.org/W4375844720","https://openalex.org/W3011705496"],"abstract_inverted_index":{"Integral":[0],"membrane":[1,33,44,62,118],"proteins":[2,181],"fulfil":[3],"important":[4],"roles":[5],"in":[6,20,41,182],"many":[7],"crucial":[8],"biological":[9],"processes,":[10],"including":[11,102],"cell":[12],"signalling,":[13],"molecular":[14,178],"transport":[15],"and":[16,89,110,117,136],"bioenergetic":[17],"processes.":[18],"Advancements":[19],"experimental":[21],"techniques":[22],"are":[23,38,125,185],"revealing":[24],"high":[25],"resolution":[26],"structures":[27,37],"for":[28,137],"an":[29],"increasing":[30],"number":[31],"of":[32,92,106,113,141,180],"proteins.":[34],"Yet,":[35],"these":[36,74],"rarely":[39],"resolved":[40],"complex":[42],"with":[43],"lipids.":[45],"In":[46,121],"2015,":[47],"the":[48,55,67,78,90,107,138,168,183],"MemProtMD":[49],"pipeline":[50],"was":[51],"developed":[52],"to":[53,77,127,175],"allow":[54],"automated":[56],"lipid":[57,114,130],"bilayer":[58,109],"assembly":[59],"around":[60],"new":[61],"protein":[63,119],"structures,":[64],"released":[65],"from":[66],"Protein":[68],"Data":[69],"Bank":[70],"(PDB).":[71],"To":[72],"make":[73],"data":[75,116],"available":[76],"scientific":[79],"community,":[80],"a":[81,99],"web":[82,100],"database":[83,140,184],"(http://memprotmd.bioch.ox.ac.uk)":[84],"has":[85],"been":[86],"developed.":[87],"Simulations":[88],"results":[91],"subsequent":[93],"analysis":[94],"can":[95],"be":[96,147],"viewed":[97],"using":[98,149,157],"browser,":[101],"interactive":[103],"3D":[104],"visualizations":[105,112],"assembled":[108],"2D":[111],"contact":[115],"topology.":[120],"addition,":[122],"ensemble":[123],"analyses":[124],"performed":[126],"detail":[128],"conserved":[129],"interaction":[131],"information":[132],"across":[133],"proteins,":[134],"families":[135],"entire":[139],"3506":[142],"PDB":[143,151],"entries.":[144],"Proteins":[145],"may":[146],"searched":[148],"keywords,":[150],"or":[152,155,167],"Uniprot":[153],"identifier,":[154],"browsed":[156],"classification":[158],"systems,":[159],"such":[160],"as":[161],"Pfam,":[162],"Gene":[163],"Ontology":[164],"annotation,":[165],"mpstruc":[166],"Transporter":[169],"Classification":[170],"Database.":[171],"All":[172],"files":[173],"required":[174],"run":[176],"further":[177],"simulations":[179],"provided.":[186]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":17},{"year":2024,"cited_by_count":41},{"year":2023,"cited_by_count":35},{"year":2022,"cited_by_count":42},{"year":2021,"cited_by_count":40},{"year":2020,"cited_by_count":24},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":1}],"updated_date":"2026-07-25T15:57:00.446498","created_date":"2025-10-10T00:00:00"}