{"id":"https://openalex.org/W2768551453","doi":"https://doi.org/10.1093/nar/gkx1139","title":"MethBank 3.0: a database of DNA methylomes across a variety of species","display_name":"MethBank 3.0: a database of DNA methylomes across a variety of species","publication_year":2017,"publication_date":"2017-10-30","ids":{"openalex":"https://openalex.org/W2768551453","doi":"https://doi.org/10.1093/nar/gkx1139","mag":"2768551453","pmid":"https://pubmed.ncbi.nlm.nih.gov/29161430"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkx1139","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkx1139","pdf_url":"https://academic.oup.com/nar/article-pdf/46/D1/D288/23162442/gkx1139.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/46/D1/D288/23162442/gkx1139.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004981004","display_name":"Rujiao Li","orcid":"https://orcid.org/0000-0002-3276-8335"},"institutions":[{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Rujiao Li","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025493439","display_name":"Liang Fang","orcid":"https://orcid.org/0000-0003-4502-1756"},"institutions":[{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fang Liang","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100785815","display_name":"Mengwei Li","orcid":"https://orcid.org/0000-0001-6163-2827"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengwei Li","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","University of Chinese Academy of Sciences, Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112583992","display_name":"Dong Zou","orcid":"https://orcid.org/0000-0002-7169-4965"},"institutions":[{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dong Zou","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084166143","display_name":"Shixiang Sun","orcid":"https://orcid.org/0000-0001-5499-2963"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shixiang Sun","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","University of Chinese Academy of Sciences, Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042127372","display_name":"Yongbing Zhao","orcid":"https://orcid.org/0000-0002-9917-7425"},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210087962","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210087962"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yongbing Zhao","raw_affiliation_strings":["Lymphocyte Nuclear Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA"],"affiliations":[{"raw_affiliation_string":"Lymphocyte Nuclear Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA","institution_ids":["https://openalex.org/I4210087962","https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090452340","display_name":"Wenming Zhao","orcid":"https://orcid.org/0000-0002-4396-8287"},"institutions":[{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenming Zhao","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","University of Chinese Academy of Sciences, Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075882065","display_name":"Y\u012bm\u00edng B\u00e0o","orcid":"https://orcid.org/0000-0002-9922-9723"},"institutions":[{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiming Bao","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","University of Chinese Academy of Sciences, Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009289581","display_name":"Jingfa Xiao","orcid":"https://orcid.org/0000-0002-2835-4340"},"institutions":[{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingfa Xiao","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200438, China","University of Chinese Academy of Sciences, Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100599306","display_name":"Zhang Zhang","orcid":"https://orcid.org/0000-0001-6603-5060"},"institutions":[{"id":"https://openalex.org/I2801577699","display_name":"Beijing Institute of Genomics","ror":"https://ror.org/049gn7z52","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2801577699"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhang Zhang","raw_affiliation_strings":["BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200438, China","University of Chinese Academy of Sciences, Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699"]},{"raw_affiliation_string":"CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I2801577699","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5004981004","https://openalex.org/A5100599306"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I24943067","https://openalex.org/I2801577699","https://openalex.org/I4210165038"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":2.0211,"has_fulltext":true,"cited_by_count":71,"citation_normalized_percentile":{"value":0.87323902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"46","issue":"D1","first_page":"D288","last_page":"D295"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9796000123023987,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9782000184059143,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.8405295610427856},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8396183252334595},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.6831517815589905},{"id":"https://openalex.org/keywords/cpg-site","display_name":"CpG site","score":0.6126057505607605},{"id":"https://openalex.org/keywords/epigenetics","display_name":"Epigenetics","score":0.5970842242240906},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.569656491279602},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.47858238220214844},{"id":"https://openalex.org/keywords/differentially-methylated-regions","display_name":"Differentially methylated regions","score":0.45313021540641785},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.37034595012664795},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.34690916538238525},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.21114128828048706},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.16975921392440796},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.12707051634788513}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.8405295610427856},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8396183252334595},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.6831517815589905},{"id":"https://openalex.org/C140173407","wikidata":"https://www.wikidata.org/wiki/Q1138358","display_name":"CpG site","level":5,"score":0.6126057505607605},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.5970842242240906},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.569656491279602},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.47858238220214844},{"id":"https://openalex.org/C154253233","wikidata":"https://www.wikidata.org/wiki/Q14862240","display_name":"Differentially methylated regions","level":5,"score":0.45313021540641785},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.37034595012664795},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.34690916538238525},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21114128828048706},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.16975921392440796},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.12707051634788513}],"mesh":[{"descriptor_ui":"D000073336","descriptor_name":"Whole Genome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073336","descriptor_name":"Whole Genome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073336","descriptor_name":"Whole Genome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003596","descriptor_name":"Cytosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003596","descriptor_name":"Cytosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003596","descriptor_name":"Cytosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018899","descriptor_name":"CpG Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018899","descriptor_name":"CpG Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018899","descriptor_name":"CpG Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/nar/gkx1139","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkx1139","pdf_url":"https://academic.oup.com/nar/article-pdf/46/D1/D288/23162442/gkx1139.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:29161430","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29161430","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:europepmc.org:4668241","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5753180","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5753180","is_oa":true,"landing_page_url":"http://doi.org/10.1093/nar/gkx1139","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"doi:10.25504/fairsharing.d1a9bd","is_oa":true,"landing_page_url":"https://doi.org/10.25504/fairsharing.d1a9bd","pdf_url":null,"source":{"id":"https://openalex.org/S7407053452","display_name":"FAIRsharing.org","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"dataset"}],"best_oa_location":{"id":"doi:10.1093/nar/gkx1139","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkx1139","pdf_url":"https://academic.oup.com/nar/article-pdf/46/D1/D288/23162442/gkx1139.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1904268823","display_name":null,"funder_award_id":"153F11KYSB20160008","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"},{"id":"https://openalex.org/G3993384610","display_name":null,"funder_award_id":"XDB13040500","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"},{"id":"https://openalex.org/G4172624199","display_name":null,"funder_award_id":"XDA08020102","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"},{"id":"https://openalex.org/G6220366374","display_name":null,"funder_award_id":"KJZD-EW-L14","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"}],"funders":[{"id":"https://openalex.org/F4320321133","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2768551453.pdf","grobid_xml":"https://content.openalex.org/works/W2768551453.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1891896752","https://openalex.org/W1974047233","https://openalex.org/W1977371925","https://openalex.org/W1990958459","https://openalex.org/W1999348612","https://openalex.org/W2005756834","https://openalex.org/W2015341005","https://openalex.org/W2017502278","https://openalex.org/W2036284273","https://openalex.org/W2055986128","https://openalex.org/W2068669644","https://openalex.org/W2068910046","https://openalex.org/W2096791950","https://openalex.org/W2113776804","https://openalex.org/W2116565281","https://openalex.org/W2118258530","https://openalex.org/W2121091193","https://openalex.org/W2123901533","https://openalex.org/W2125477221","https://openalex.org/W2127431419","https://openalex.org/W2132762836","https://openalex.org/W2146794662","https://openalex.org/W2159536887","https://openalex.org/W2161148315","https://openalex.org/W2164550220","https://openalex.org/W2165446840","https://openalex.org/W2166186613","https://openalex.org/W2167021978","https://openalex.org/W2259285077","https://openalex.org/W2304569214","https://openalex.org/W2329888282","https://openalex.org/W2461153930","https://openalex.org/W2491158000","https://openalex.org/W2505539351","https://openalex.org/W2509237444","https://openalex.org/W2549309609","https://openalex.org/W2557962097","https://openalex.org/W2578400498","https://openalex.org/W2581180469","https://openalex.org/W2583735774","https://openalex.org/W2605265780","https://openalex.org/W2663574681","https://openalex.org/W2755227704","https://openalex.org/W2768551453","https://openalex.org/W4213257593","https://openalex.org/W4238719510"],"related_works":["https://openalex.org/W1662175115","https://openalex.org/W2214376880","https://openalex.org/W3212149434","https://openalex.org/W2073893804","https://openalex.org/W2291484187","https://openalex.org/W2902329290","https://openalex.org/W2169344098","https://openalex.org/W2045854104","https://openalex.org/W4286742095","https://openalex.org/W2150651400"],"abstract_inverted_index":{"MethBank":[0,32,63,156,174],"(http://bigd.big.ac.cn/methbank)":[1],"is":[2,115,175,187],"a":[3,11,78],"database":[4],"that":[5],"integrates":[6],"high-quality":[7,69],"DNA":[8,38,193],"methylomes":[9,39,75,87,101],"across":[10,141],"variety":[12],"of":[13,22,31,68,81,94,110,129,188],"species":[14,42],"and":[15,43,52,61,97,104,151,165,180],"provides":[16,157],"an":[17,28],"interactive":[18],"browser":[19],"for":[20,49,57,121,191,197],"visualization":[21],"methylation":[23,130,139,162,194],"data.":[24],"Here,":[25],"we":[26],"present":[27],"updated":[29],"implementation":[30],"(version":[33],"3.0)":[34],"by":[35,117],"incorporating":[36],"more":[37,46,53],"from":[40,77,88,102],"multiple":[41,108],"equipping":[44],"with":[45,134,137,177],"enhanced":[47,116],"functionalities":[48,120],"data":[50,58,122],"annotation":[51],"friendly":[54],"web":[55],"interfaces":[56],"presentation,":[59],"search":[60],"visualization.":[62],"3.0":[64],"features":[65],"large-scale":[66],"integration":[67],"methylomes,":[70],"involving":[71],"34":[72],"consensus":[73],"reference":[74],"derived":[76],"large":[79],"number":[80],"human":[82,161],"samples,":[83],"336":[84],"single-base":[85,99],"resolution":[86,100],"different":[89,142],"developmental":[90],"stages":[91,109],"and/or":[92],"tissues":[93],"five":[95],"plants,":[96],"18":[98],"gametes":[103],"early":[105],"embryos":[106],"at":[107],"two":[111],"animals.":[112],"Additionally,":[113],"it":[114],"improving":[118],"the":[119,183],"annotation,":[123],"which":[124,186],"accordingly":[125],"enables":[126],"systematic":[127],"identification":[128],"sites":[131,136],"closely":[132],"associated":[133],"age,":[135],"constant":[138],"levels":[140],"ages,":[143],"differentially":[144,148,168],"methylated":[145,149,152,169],"promoters,":[146,170],"age-specific":[147],"cytosines/regions,":[150],"CpG":[153],"islands.":[154],"Moreover,":[155],"tools":[158],"to":[159,166],"estimate":[160],"age":[163],"online":[164],"identify":[167],"respectively.":[171],"Taken":[172],"together,":[173],"upgraded":[176],"significant":[178],"improvements":[179],"advances":[181],"over":[182],"previous":[184],"version,":[185],"great":[189],"help":[190],"deciphering":[192],"regulatory":[195],"mechanisms":[196],"epigenetic":[198],"studies.":[199]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2017-12-04T00:00:00"}