{"id":"https://openalex.org/W2765648964","doi":"https://doi.org/10.1093/nar/gkx1014","title":"ASpedia: a comprehensive encyclopedia of human alternative splicing","display_name":"ASpedia: a comprehensive encyclopedia of human alternative splicing","publication_year":2017,"publication_date":"2017-10-13","ids":{"openalex":"https://openalex.org/W2765648964","doi":"https://doi.org/10.1093/nar/gkx1014","mag":"2765648964","pmid":"https://pubmed.ncbi.nlm.nih.gov/29106599"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkx1014","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkx1014","pdf_url":"https://academic.oup.com/nar/article-pdf/46/D1/D58/23161940/gkx1014.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/46/D1/D58/23161940/gkx1014.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035089426","display_name":"Daejin Hyung","orcid":"https://orcid.org/0000-0002-4843-089X"},"institutions":[{"id":"https://openalex.org/I4210120052","display_name":"National Cancer Center","ror":"https://ror.org/02tsanh21","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I1290491151","https://openalex.org/I2801339556","https://openalex.org/I4210120052"]},{"id":"https://openalex.org/I51226738","display_name":"Dong-A University","ror":"https://ror.org/03qvtpc38","country_code":"KR","type":"education","lineage":["https://openalex.org/I51226738"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Daejin Hyung","raw_affiliation_strings":["Department of Computer Engineering, Dong-A University, 37 Nakdong-daero 550 Beon-gil, Saha-gu, Busan 49315, Republic of Korea","Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang-si, Kyeonggi-do 10408, Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Department of Computer Engineering, Dong-A University, 37 Nakdong-daero 550 Beon-gil, Saha-gu, Busan 49315, Republic of Korea","institution_ids":["https://openalex.org/I51226738"]},{"raw_affiliation_string":"Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang-si, Kyeonggi-do 10408, Republic of Korea","institution_ids":["https://openalex.org/I4210120052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100462791","display_name":"Jihyun Kim","orcid":"https://orcid.org/0000-0003-0195-4319"},"institutions":[{"id":"https://openalex.org/I4210120052","display_name":"National Cancer Center","ror":"https://ror.org/02tsanh21","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I1290491151","https://openalex.org/I2801339556","https://openalex.org/I4210120052"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jihyun Kim","raw_affiliation_strings":["Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang-si, Kyeonggi-do 10408, Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang-si, Kyeonggi-do 10408, Republic of Korea","institution_ids":["https://openalex.org/I4210120052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031528316","display_name":"Soo Young Cho","orcid":"https://orcid.org/0000-0002-2960-9878"},"institutions":[{"id":"https://openalex.org/I4210120052","display_name":"National Cancer Center","ror":"https://ror.org/02tsanh21","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I1290491151","https://openalex.org/I2801339556","https://openalex.org/I4210120052"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Soo Young Cho","raw_affiliation_strings":["Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang-si, Kyeonggi-do 10408, Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang-si, Kyeonggi-do 10408, Republic of Korea","institution_ids":["https://openalex.org/I4210120052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088547825","display_name":"Charny Park","orcid":"https://orcid.org/0000-0001-5857-7695"},"institutions":[{"id":"https://openalex.org/I4210120052","display_name":"National Cancer Center","ror":"https://ror.org/02tsanh21","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I1290491151","https://openalex.org/I2801339556","https://openalex.org/I4210120052"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Charny Park","raw_affiliation_strings":["Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang-si, Kyeonggi-do 10408, Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang-si, Kyeonggi-do 10408, Republic of Korea","institution_ids":["https://openalex.org/I4210120052"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5031528316","https://openalex.org/A5088547825"],"corresponding_institution_ids":["https://openalex.org/I4210120052"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":1.7962,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.85512164,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"46","issue":"D1","first_page":"D58","last_page":"D63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8160005211830139},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"Alternative splicing","score":0.7763007879257202},{"id":"https://openalex.org/keywords/rna-splicing","display_name":"RNA splicing","score":0.7533082365989685},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.6453137397766113},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5970355868339539},{"id":"https://openalex.org/keywords/human-genome","display_name":"Human genome","score":0.5368682742118835},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4656204879283905},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.4454028010368347},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.23641619086265564},{"id":"https://openalex.org/keywords/gene-isoform","display_name":"Gene isoform","score":0.23334789276123047},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.21172666549682617}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8160005211830139},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.7763007879257202},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.7533082365989685},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.6453137397766113},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5970355868339539},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.5368682742118835},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4656204879283905},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4454028010368347},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.23641619086265564},{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.23334789276123047},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21172666549682617}],"mesh":[{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkx1014","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkx1014","pdf_url":"https://academic.oup.com/nar/article-pdf/46/D1/D58/23161940/gkx1014.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:29106599","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29106599","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:5753336","is_oa":true,"landing_page_url":"http://doi.org/10.1093/nar/gkx1014","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkx1014","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkx1014","pdf_url":"https://academic.oup.com/nar/article-pdf/46/D1/D58/23161940/gkx1014.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1274167916","display_name":null,"funder_award_id":"NRF-2014","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G342704958","display_name":null,"funder_award_id":"funded","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G4244126222","display_name":null,"funder_award_id":"NRF-2016","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G4455342202","display_name":null,"funder_award_id":"64815","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G5457564767","display_name":null,"funder_award_id":"NRF-2016R1D1A","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G8026418486","display_name":null,"funder_award_id":"2016R1D1A1B0393","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G8937434810","display_name":null,"funder_award_id":"2014M","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G982292920","display_name":null,"funder_award_id":"NRF-20","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"}],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2765648964.pdf","grobid_xml":"https://content.openalex.org/works/W2765648964.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1985217779","https://openalex.org/W2011920499","https://openalex.org/W2012649419","https://openalex.org/W2023506303","https://openalex.org/W2041341260","https://openalex.org/W2043274355","https://openalex.org/W2057306271","https://openalex.org/W2066231767","https://openalex.org/W2087558745","https://openalex.org/W2088338354","https://openalex.org/W2092819668","https://openalex.org/W2094201044","https://openalex.org/W2096525273","https://openalex.org/W2097277153","https://openalex.org/W2102937449","https://openalex.org/W2103823493","https://openalex.org/W2117513900","https://openalex.org/W2117949279","https://openalex.org/W2118151336","https://openalex.org/W2126669467","https://openalex.org/W2128016314","https://openalex.org/W2128128648","https://openalex.org/W2131271579","https://openalex.org/W2138397090","https://openalex.org/W2157221164","https://openalex.org/W2159730169","https://openalex.org/W2163516449","https://openalex.org/W2167898988","https://openalex.org/W2169456326","https://openalex.org/W2176981778","https://openalex.org/W2224056471","https://openalex.org/W2258573009","https://openalex.org/W2606823712","https://openalex.org/W3042475334","https://openalex.org/W4234797890"],"related_works":["https://openalex.org/W2321791250","https://openalex.org/W4213427798","https://openalex.org/W2023199111","https://openalex.org/W2564462691","https://openalex.org/W2065030615","https://openalex.org/W2885403345","https://openalex.org/W2052498125","https://openalex.org/W4387768639","https://openalex.org/W2094867951","https://openalex.org/W1535548930"],"abstract_inverted_index":{"Alternative":[0],"splicing":[1,18,26,42,77,92,165],"confers":[2],"the":[3,9,37,52,160,180,189,193],"human":[4,90,163],"genome":[5,184],"complexity":[6],"by":[7,75],"increasing":[8],"diversity":[10],"of":[11,17,28,40,56,98,162,192,196],"expressed":[12],"mRNAs.":[13],"Hundreds":[14],"or":[15],"thousands":[16],"regions":[19],"have":[20],"been":[21],"identified":[22],"through":[23],"differential":[24],"alternative":[25,76,91,164],"analysis":[27,178],"high-throughput":[29,177],"datasets.":[30,141],"However,":[31,58],"it":[32],"is":[33],"hard":[34],"to":[35,103],"explain":[36],"functional":[38,54,60,194],"impact":[39],"each":[41],"event.":[43],"Protein":[44],"domain":[45],"formation":[46],"and":[47,69,78,120,124,132,139,155,179],"nonsense-mediated":[48],"decay":[49],"are":[50,72],"considered":[51],"main":[53],"features":[55,61],"splicing.":[57],"other":[59],"such":[62],"as":[63],"miRNA":[64],"target":[65],"sites,":[66],"phosphorylation":[67],"sites":[68],"single-nucleotide":[70],"variations":[71],"directly":[73],"affected":[74],"affect":[79],"downstream":[80],"function.":[81],"Hence,":[82],"we":[83],"established":[84],"ASpedia:":[85],"a":[86,96,152,156],"comprehensive":[87],"database":[88,109],"for":[89],"annotation,":[93],"which":[94],"encompasses":[95],"range":[97],"functions,":[99],"from":[100,117,128,137,176],"genomic":[101,114],"annotation":[102,115,150,191],"isoform-specific":[104,134],"function":[105],"(ASpedia,":[106],"http://combio.snu.ac.kr/aspedia).":[107],"The":[108,142,167],"provides":[110],"three":[111,147],"features:":[112],"(i)":[113],"extracted":[116],"DNA,":[118],"RNA":[119],"proteins;":[121],"(ii)":[122],"transcription":[123],"regulation":[125],"elements":[126],"analyzed":[127],"next-generation":[129],"sequencing":[130],"datasets;":[131],"(iii)":[133],"functions":[135],"collected":[136],"known":[138],"published":[140],"ASpedia":[143,187],"web":[144],"application":[145],"includes":[146],"components:":[148],"an":[149],"database,":[151],"retrieval":[153,168],"system":[154,169],"browser":[157,182],"specialized":[158],"in":[159],"identification":[161],"events.":[166,199],"supports":[170],"multiple":[171,197],"AS":[172,181,198],"event":[173],"searches":[174],"resulting":[175],"comprises":[183],"tracks.":[185],"Thus,":[186],"facilitates":[188],"systemic":[190],"impacts":[195]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":5}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}