{"id":"https://openalex.org/W2558366645","doi":"https://doi.org/10.1093/nar/gkw1072","title":"Pharos: Collating protein information to shed light on the druggable genome","display_name":"Pharos: Collating protein information to shed light on the druggable genome","publication_year":2016,"publication_date":"2016-10-24","ids":{"openalex":"https://openalex.org/W2558366645","doi":"https://doi.org/10.1093/nar/gkw1072","mag":"2558366645","pmid":"https://pubmed.ncbi.nlm.nih.gov/27903890"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkw1072","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkw1072","pdf_url":"https://academic.oup.com/nar/article-pdf/45/D1/D995/8846748/gkw1072.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/45/D1/D995/8846748/gkw1072.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061179559","display_name":"\u00d0\u1eafc-Trung Nguy\u1ec5n","orcid":"https://orcid.org/0000-0003-2591-9948"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dac-Trung Nguyen","raw_affiliation_strings":["National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018966195","display_name":"Stephen L. Mathias","orcid":"https://orcid.org/0000-0002-7255-370X"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen Mathias","raw_affiliation_strings":["Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053220470","display_name":"Cristian Bologa","orcid":"https://orcid.org/0000-0003-2232-4244"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristian Bologa","raw_affiliation_strings":["Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011862057","display_name":"S\u00f8ren Brunak","orcid":"https://orcid.org/0000-0003-0316-5866"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Soren Brunak","raw_affiliation_strings":["Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark"],"affiliations":[{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102932473","display_name":"Nicolas Fernandez","orcid":"https://orcid.org/0000-0001-7979-2941"},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicolas Fernandez","raw_affiliation_strings":["Mount Sinai Center for Bioinformatics, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA"],"affiliations":[{"raw_affiliation_string":"Mount Sinai Center for Bioinformatics, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050930900","display_name":"Anna Gaulton","orcid":"https://orcid.org/0000-0003-2634-7400"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anna Gaulton","raw_affiliation_strings":["European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK","European Molecular Biology Laboratory \u2013 European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK","institution_ids":[]},{"raw_affiliation_string":"European Molecular Biology Laboratory \u2013 European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003544163","display_name":"Anne Hersey","orcid":"https://orcid.org/0000-0003-4679-6211"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anne Hersey","raw_affiliation_strings":["European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK","European Molecular Biology Laboratory \u2013 European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK","institution_ids":[]},{"raw_affiliation_string":"European Molecular Biology Laboratory \u2013 European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031552923","display_name":"Jayme Holmes","orcid":"https://orcid.org/0000-0003-3109-5228"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jayme Holmes","raw_affiliation_strings":["Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005772961","display_name":"Lars Juhl Jensen","orcid":"https://orcid.org/0000-0001-7885-715X"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Lars Juhl Jensen","raw_affiliation_strings":["Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark"],"affiliations":[{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103252654","display_name":"Anneli Karlsson","orcid":"https://orcid.org/0000-0001-5155-4327"},"institutions":[{"id":"https://openalex.org/I4210122598","display_name":"BenevolentAI (United Kingdom)","ror":"https://ror.org/02z480994","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210122598"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anneli Karlsson","raw_affiliation_strings":["BenevolentAI, 40 Churchway, London NW1 1LW, UK"],"affiliations":[{"raw_affiliation_string":"BenevolentAI, 40 Churchway, London NW1 1LW, UK","institution_ids":["https://openalex.org/I4210122598"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101576373","display_name":"Guixia Liu","orcid":"https://orcid.org/0000-0001-9648-844X"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Guixia Liu","raw_affiliation_strings":["East China University of Science and Technology, Dept. Pharmaceutical Sciences, Shanghai, China","Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"East China University of Science and Technology, Dept. Pharmaceutical Sciences, Shanghai, China","institution_ids":["https://openalex.org/I143593769"]},{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032951414","display_name":"Avi Ma\u2019ayan","orcid":"https://orcid.org/0000-0002-6904-1017"},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Avi Ma'ayan","raw_affiliation_strings":["Mount Sinai Center for Bioinformatics, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA"],"affiliations":[{"raw_affiliation_string":"Mount Sinai Center for Bioinformatics, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073575015","display_name":"Geetha Mandava","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Geetha Mandava","raw_affiliation_strings":["National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035264371","display_name":"Subramani Mani","orcid":null},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Subramani Mani","raw_affiliation_strings":["Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049305933","display_name":"Saurabh Mehta","orcid":"https://orcid.org/0000-0002-9174-128X"},"institutions":[{"id":"https://openalex.org/I863896202","display_name":"Delhi Technological University","ror":"https://ror.org/01ztcvt22","country_code":"IN","type":"education","lineage":["https://openalex.org/I863896202"]},{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["IN","US"],"is_corresponding":false,"raw_author_name":"Saurabh Mehta","raw_affiliation_strings":["Center for Computational Science, University of Miami, Coral Gables, FL 33146, USA","Department of Applied Chemistry, Delhi Technological University, Delhi 110042, India"],"affiliations":[{"raw_affiliation_string":"Center for Computational Science, University of Miami, Coral Gables, FL 33146, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Applied Chemistry, Delhi Technological University, Delhi 110042, India","institution_ids":["https://openalex.org/I863896202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001723208","display_name":"John P. Overington","orcid":"https://orcid.org/0000-0002-5859-1064"},"institutions":[{"id":"https://openalex.org/I4210122598","display_name":"BenevolentAI (United Kingdom)","ror":"https://ror.org/02z480994","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210122598"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John Overington","raw_affiliation_strings":["BenevolentAI, 40 Churchway, London NW1 1LW, UK"],"affiliations":[{"raw_affiliation_string":"BenevolentAI, 40 Churchway, London NW1 1LW, UK","institution_ids":["https://openalex.org/I4210122598"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034204286","display_name":"Juhee Patel","orcid":null},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juhee Patel","raw_affiliation_strings":["BA/MD Program, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"BA/MD Program, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]},{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007100650","display_name":"Andrew D. Rouillard","orcid":"https://orcid.org/0000-0002-3502-7161"},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew D. Rouillard","raw_affiliation_strings":["Mount Sinai Center for Bioinformatics, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA"],"affiliations":[{"raw_affiliation_string":"Mount Sinai Center for Bioinformatics, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013636406","display_name":"Stephan C. Sch\u00fcrer","orcid":"https://orcid.org/0000-0001-7180-0978"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephan Sch\u00fcrer","raw_affiliation_strings":["Center for Computational Science, University of Miami, Coral Gables, FL 33146, USA","Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA"],"affiliations":[{"raw_affiliation_string":"Center for Computational Science, University of Miami, Coral Gables, FL 33146, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058858658","display_name":"Timothy Sheils","orcid":"https://orcid.org/0000-0002-9987-3738"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy Sheils","raw_affiliation_strings":["National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059969497","display_name":"Anton Simeonov","orcid":"https://orcid.org/0000-0002-4523-9977"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anton Simeonov","raw_affiliation_strings":["National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028187863","display_name":"Larry A. Sklar","orcid":"https://orcid.org/0000-0002-8196-5060"},"institutions":[{"id":"https://openalex.org/I4210141130","display_name":"New Mexico Cancer Center","ror":"https://ror.org/03emyr182","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210141130"]},{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Larry A. Sklar","raw_affiliation_strings":["Center for Molecular Discovery, University of New Mexico Cancer Center, University of New Mexico, Albuquerque, NM 87131, USA","Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Center for Molecular Discovery, University of New Mexico Cancer Center, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I4210141130","https://openalex.org/I169521973"]},{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036261394","display_name":"Noel Southall","orcid":"https://orcid.org/0000-0003-4500-880X"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Noel Southall","raw_affiliation_strings":["National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064097191","display_name":"Oleg Ursu","orcid":"https://orcid.org/0000-0003-0596-8339"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oleg Ursu","raw_affiliation_strings":["Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028217875","display_name":"D. Vidovi\u0107","orcid":"https://orcid.org/0000-0001-9798-2108"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dusica Vidovic","raw_affiliation_strings":["Center for Computational Science, University of Miami, Coral Gables, FL 33146, USA","Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA"],"affiliations":[{"raw_affiliation_string":"Center for Computational Science, University of Miami, Coral Gables, FL 33146, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014727189","display_name":"Anna Waller","orcid":"https://orcid.org/0000-0003-3676-2501"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4210141130","display_name":"New Mexico Cancer Center","ror":"https://ror.org/03emyr182","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210141130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anna Waller","raw_affiliation_strings":["Center for Molecular Discovery, University of New Mexico Cancer Center, University of New Mexico, Albuquerque, NM 87131, USA","Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Center for Molecular Discovery, University of New Mexico Cancer Center, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I4210141130","https://openalex.org/I169521973"]},{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076911664","display_name":"Jeremy J. Yang","orcid":"https://orcid.org/0000-0002-1476-6192"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy Yang","raw_affiliation_strings":["Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061786031","display_name":"Ajit Jadhav","orcid":"https://orcid.org/0000-0001-7955-1451"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ajit Jadhav","raw_affiliation_strings":["National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061685157","display_name":"Tudor I. Oprea","orcid":"https://orcid.org/0000-0002-6195-6976"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tudor I. Oprea","raw_affiliation_strings":["Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA toprea@salud.unm.edu","Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA toprea@salud.unm.edu","institution_ids":[]},{"raw_affiliation_string":"Translational Informatics Division, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069062997","display_name":"Rajarshi Guha","orcid":"https://orcid.org/0000-0001-7403-8819"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rajarshi Guha","raw_affiliation_strings":["National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA guhar@mail.nih.gov","National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA guhar@mail.nih.gov","institution_ids":[]},{"raw_affiliation_string":"National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I4210148682"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":30,"corresponding_author_ids":["https://openalex.org/A5069062997"],"corresponding_institution_ids":["https://openalex.org/I4210148682"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":29.47,"has_fulltext":true,"cited_by_count":317,"citation_normalized_percentile":{"value":0.99744823,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"45","issue":"D1","first_page":"D995","last_page":"D1002"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9941999912261963,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/druggability","display_name":"Druggability","score":0.9603028297424316},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.6092842221260071},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5019395351409912},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.491929292678833},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4910573959350586},{"id":"https://openalex.org/keywords/resource","display_name":"Resource (disambiguation)","score":0.4148935377597809},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3632144629955292},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.3456292152404785},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2562868595123291},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.17266622185707092}],"concepts":[{"id":"https://openalex.org/C10679952","wikidata":"https://www.wikidata.org/wiki/Q5308937","display_name":"Druggability","level":3,"score":0.9603028297424316},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.6092842221260071},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5019395351409912},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.491929292678833},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4910573959350586},{"id":"https://openalex.org/C206345919","wikidata":"https://www.wikidata.org/wiki/Q20380951","display_name":"Resource (disambiguation)","level":2,"score":0.4148935377597809},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3632144629955292},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.3456292152404785},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2562868595123291},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17266622185707092},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C55352822","wikidata":"https://www.wikidata.org/wiki/Q5558978","display_name":"Gibbs isotherm","level":3,"score":0.0},{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057386","descriptor_name":"Search Engine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057386","descriptor_name":"Search Engine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057386","descriptor_name":"Search Engine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064878","descriptor_name":"Web Browser","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064878","descriptor_name":"Web Browser","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064878","descriptor_name":"Web Browser","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/nar/gkw1072","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkw1072","pdf_url":"https://academic.oup.com/nar/article-pdf/45/D1/D995/8846748/gkw1072.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:27903890","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27903890","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:open-archive.highwire.org:nar:45/D1/D995","is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/45/D1/D995","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:pubmedcentral.nih.gov:5210555","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5210555","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/996721e5-e61b-499c-955c-9c227da8a957","is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/996721e5-e61b-499c-955c-9c227da8a957","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nguyen , D-T , Mathias , S , Bologa , C , Brunak , S , Fernandez , N , Gaulton , A , Hersey , A , Holmes , J , Jensen , L J , Karlsson , A , Liu , G , Ma'ayan , A , Mandava , G , Mani , S , Mehta , S , Overington , J , Patel , J , Rouillard , A D , Sch\u00fcrer , S , Sheils , T , Simeonov , A , Sklar , L A , Southall , N , Ursu , O , Vidovic , D , Waller , A , Yang , J , Jadhav , A , Oprea , T I & Guha , R 2017 , ' Pharos : Collating protein information to shed light on the druggable genome ' , Nucleic Acids Research , vol. 45 , no. D1 , pp. D995\u2013D1002 . https://doi.org/10.1093/nar/gkw1072","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1093/nar/gkw1072","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkw1072","pdf_url":"https://academic.oup.com/nar/article-pdf/45/D1/D995/8846748/gkw1072.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9","score":0.4000000059604645}],"awards":[{"id":"https://openalex.org/G2789588635","display_name":null,"funder_award_id":"NCATS","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3497591915","display_name":null,"funder_award_id":"(NIH)","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4282887365","display_name":null,"funder_award_id":"NNF14CC0001","funder_id":"https://openalex.org/F4320322436","funder_display_name":"Novo Nordisk"},{"id":"https://openalex.org/G6662978750","display_name":null,"funder_award_id":"NNF14CC0001","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G7031468586","display_name":null,"funder_award_id":"NNF14CC000","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G996161988","display_name":null,"funder_award_id":"14CC0001","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"}],"funders":[{"id":"https://openalex.org/F4320322436","display_name":"Novo Nordisk","ror":"https://ror.org/0435rc536"},{"id":"https://openalex.org/F4320325957","display_name":"Novo Nordisk Fonden","ror":"https://ror.org/04txyc737"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320338403","display_name":"Common Fund","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2558366645.pdf","grobid_xml":"https://content.openalex.org/works/W2558366645.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1975875968","https://openalex.org/W2012750155","https://openalex.org/W2018518196","https://openalex.org/W2074370114","https://openalex.org/W2078744455","https://openalex.org/W2099388354","https://openalex.org/W2103017472","https://openalex.org/W2114347076","https://openalex.org/W2133332129","https://openalex.org/W2159092541","https://openalex.org/W2194756172","https://openalex.org/W2202954603","https://openalex.org/W2223549218","https://openalex.org/W2227583040","https://openalex.org/W2346012195","https://openalex.org/W2462053388","https://openalex.org/W2474747771","https://openalex.org/W2493614923","https://openalex.org/W2539985226","https://openalex.org/W2558217333","https://openalex.org/W2739999456","https://openalex.org/W3101707886"],"related_works":["https://openalex.org/W2556855892","https://openalex.org/W4280541024","https://openalex.org/W4214810602","https://openalex.org/W2523769397","https://openalex.org/W2000687555","https://openalex.org/W4290613495","https://openalex.org/W3174373983","https://openalex.org/W2099388354","https://openalex.org/W2745208859","https://openalex.org/W2999980799"],"abstract_inverted_index":{"The":[0,28,140],"'druggable":[1],"genome'":[2],"encompasses":[3],"several":[4],"protein":[5,59],"families,":[6,63],"but":[7],"only":[8],"a":[9,47,100],"subset":[10],"of":[11,42,117,127,142,168],"targets":[12,60,69],"within":[13],"them":[14,25],"have":[15,22],"attracted":[16],"significant":[17],"research":[18],"attention":[19],"and":[20,46,55,97,115,123,170],"thus":[21],"information":[23,57,152],"about":[24,58],"publicly":[26],"available.":[27],"Illuminating":[29],"the":[30,40,65,83,85,106,113,121,128,137,166],"Druggable":[31],"Genome":[32],"(IDG)":[33],"program":[34],"was":[35],"initiated":[36],"in":[37],"2014,":[38],"has":[39],"goal":[41],"developing":[43],"experimental":[44],"techniques":[45],"Knowledge":[48],"Management":[49],"Center":[50],"(KMC)":[51],"that":[52,104,164],"would":[53],"collect":[54],"organize":[56],"from":[61,108],"four":[62],"representing":[64],"most":[66],"common":[67],"druggable":[68],"with":[70],"an":[71],"emphasis":[72],"on":[73],"understudied":[74],"proteins.":[75],"Here,":[76],"we":[77],"describe":[78,112],"two":[79,161],"resources":[80],"developed":[81],"by":[82,120,159],"KMC:":[84],"Target":[86],"Central":[87],"Resource":[88],"Database":[89],"(TCRD)":[90],"which":[91],"collates":[92],"many":[93],"heterogeneous":[94],"gene/protein":[95],"datasets":[96],"Pharos":[98,129,143,169],"(https://pharos.nih.gov),":[99],"multimodal":[101],"web":[102],"interface":[103,130],"presents":[105],"data":[107,118],"TCRD.":[109,171],"We":[110,157],"briefly":[111],"types":[114],"sources":[116],"considered":[119],"KMC":[122],"then":[124],"highlight":[125,165],"features":[126],"designed":[131],"to":[132,136,145],"enable":[133],"intuitive":[134],"access":[135],"IDG":[138],"knowledgebase.":[139],"aim":[141],"is":[144,153],"encourage":[146],"'serendipitous":[147],"browsing',":[148],"whereby":[149],"related,":[150],"relevant":[151],"made":[154],"easily":[155],"discoverable.":[156],"conclude":[158],"describing":[160],"use":[162],"cases":[163],"utility":[167]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":45},{"year":2023,"cited_by_count":36},{"year":2022,"cited_by_count":44},{"year":2021,"cited_by_count":31},{"year":2020,"cited_by_count":53},{"year":2019,"cited_by_count":40},{"year":2018,"cited_by_count":27},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}