{"id":"https://openalex.org/W2174652193","doi":"https://doi.org/10.1093/nar/gkv1313","title":"EK3D: an<i>E</i>.<i>coli</i>\u00a0K antigen 3-dimensional structure database","display_name":"EK3D: an<i>E</i>.<i>coli</i>\u00a0K antigen 3-dimensional structure database","publication_year":2015,"publication_date":"2015-11-28","ids":{"openalex":"https://openalex.org/W2174652193","doi":"https://doi.org/10.1093/nar/gkv1313","mag":"2174652193","pmid":"https://pubmed.ncbi.nlm.nih.gov/26615200"},"language":"he","primary_location":{"id":"doi:10.1093/nar/gkv1313","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1313","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D675/16661871/gkv1313.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/44/D1/D675/16661871/gkv1313.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012550988","display_name":"Bharathi Reddy Kunduru","orcid":null},"institutions":[{"id":"https://openalex.org/I65181880","display_name":"Indian Institute of Technology Hyderabad","ror":"https://ror.org/01j4v3x97","country_code":"IN","type":"education","lineage":["https://openalex.org/I65181880"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bharathi Reddy Kunduru","raw_affiliation_strings":["Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India","institution_ids":["https://openalex.org/I65181880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083872739","display_name":"Sanjana Nair","orcid":"https://orcid.org/0000-0002-1861-417X"},"institutions":[{"id":"https://openalex.org/I65181880","display_name":"Indian Institute of Technology Hyderabad","ror":"https://ror.org/01j4v3x97","country_code":"IN","type":"education","lineage":["https://openalex.org/I65181880"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sanjana Anilkumar Nair","raw_affiliation_strings":["Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India","institution_ids":["https://openalex.org/I65181880"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000179508","display_name":"Thenmalarchelvi Rathinavelan","orcid":"https://orcid.org/0000-0002-1142-0583"},"institutions":[{"id":"https://openalex.org/I65181880","display_name":"Indian Institute of Technology Hyderabad","ror":"https://ror.org/01j4v3x97","country_code":"IN","type":"education","lineage":["https://openalex.org/I65181880"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Thenmalarchelvi Rathinavelan","raw_affiliation_strings":["Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India tr@iith.ac.in","Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India tr@iith.ac.in","institution_ids":["https://openalex.org/I65181880"]},{"raw_affiliation_string":"Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India","institution_ids":["https://openalex.org/I65181880"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5000179508"],"corresponding_institution_ids":["https://openalex.org/I65181880"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":0.5445,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.59331206,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"44","issue":"D1","first_page":"D675","last_page":"D681"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8122783899307251},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.7162976861000061},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.6855427622795105},{"id":"https://openalex.org/keywords/antigen","display_name":"Antigen","score":0.6114809513092041},{"id":"https://openalex.org/keywords/bacterial-outer-membrane","display_name":"Bacterial outer membrane","score":0.5805926322937012},{"id":"https://openalex.org/keywords/virulence","display_name":"Virulence","score":0.5630056262016296},{"id":"https://openalex.org/keywords/bacteria","display_name":"Bacteria","score":0.5520117282867432},{"id":"https://openalex.org/keywords/enterobacteriaceae","display_name":"Enterobacteriaceae","score":0.5303890109062195},{"id":"https://openalex.org/keywords/salmonella","display_name":"Salmonella","score":0.5107507705688477},{"id":"https://openalex.org/keywords/shigella","display_name":"Shigella","score":0.48535242676734924},{"id":"https://openalex.org/keywords/serotype","display_name":"Serotype","score":0.46422502398490906},{"id":"https://openalex.org/keywords/multiple-drug-resistance","display_name":"Multiple drug resistance","score":0.449418842792511},{"id":"https://openalex.org/keywords/pathogen","display_name":"Pathogen","score":0.4208885133266449},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"Antibiotic resistance","score":0.4156317710876465},{"id":"https://openalex.org/keywords/antibiotics","display_name":"Antibiotics","score":0.33123278617858887},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.21732065081596375},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2132926881313324}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8122783899307251},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.7162976861000061},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6855427622795105},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6114809513092041},{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.5805926322937012},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.5630056262016296},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.5520117282867432},{"id":"https://openalex.org/C2778910516","wikidata":"https://www.wikidata.org/wiki/Q380136","display_name":"Enterobacteriaceae","level":4,"score":0.5303890109062195},{"id":"https://openalex.org/C2781065037","wikidata":"https://www.wikidata.org/wiki/Q150839","display_name":"Salmonella","level":3,"score":0.5107507705688477},{"id":"https://openalex.org/C2776986154","wikidata":"https://www.wikidata.org/wiki/Q131029","display_name":"Shigella","level":4,"score":0.48535242676734924},{"id":"https://openalex.org/C10389963","wikidata":"https://www.wikidata.org/wiki/Q848328","display_name":"Serotype","level":2,"score":0.46422502398490906},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.449418842792511},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.4208885133266449},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.4156317710876465},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.33123278617858887},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21732065081596375},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2132926881313324}],"mesh":[{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011135","descriptor_name":"Polysaccharides, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011135","descriptor_name":"Polysaccharides, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011135","descriptor_name":"Polysaccharides, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D062126","descriptor_name":"Databases, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062126","descriptor_name":"Databases, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062126","descriptor_name":"Databases, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/nar/gkv1313","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1313","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D675/16661871/gkv1313.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:26615200","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26615200","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:europepmc.org:3680833","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4702918","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:nar:44/D1/D675","is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/44/D1/D675","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1093/nar/gkv1313","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1313","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D675/16661871/gkv1313.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8199999928474426,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W130261659","https://openalex.org/W1966597734","https://openalex.org/W1969493239","https://openalex.org/W1981338975","https://openalex.org/W1999479012","https://openalex.org/W2016411536","https://openalex.org/W2019701333","https://openalex.org/W2020379385","https://openalex.org/W2021520922","https://openalex.org/W2023256284","https://openalex.org/W2029600545","https://openalex.org/W2051279113","https://openalex.org/W2056090070","https://openalex.org/W2065276821","https://openalex.org/W2067594789","https://openalex.org/W2069262457","https://openalex.org/W2087606064","https://openalex.org/W2087928405","https://openalex.org/W2096512472","https://openalex.org/W2101715375","https://openalex.org/W2106488038","https://openalex.org/W2107155599","https://openalex.org/W2107317356","https://openalex.org/W2117319600","https://openalex.org/W2124381039","https://openalex.org/W2128639098","https://openalex.org/W2132262459","https://openalex.org/W2160122845","https://openalex.org/W4252936206"],"related_works":["https://openalex.org/W2922253088","https://openalex.org/W1973202984","https://openalex.org/W2091756335","https://openalex.org/W1805242609","https://openalex.org/W3029759135","https://openalex.org/W2150899647","https://openalex.org/W2334596354","https://openalex.org/W2054468945","https://openalex.org/W2469612095","https://openalex.org/W2396258377"],"abstract_inverted_index":{"A":[0],"very":[1],"high":[2],"rate":[3],"of":[4,29,34,82,103,156,183,187],"multidrug":[5],"resistance":[6,168],"(MDR)":[7],"seen":[8],"among":[9],"Gram-negative":[10,35],"bacteria":[11,36],"such":[12],"as":[13,66,68,164],"Escherichia,":[14],"Klebsiella,":[15],"Salmonella,":[16],"Shigella,":[17],"etc.":[18],"is":[19,37,51,85],"a":[20,52,60,99,150],"major":[21,31,171],"threat":[22],"to":[23,89,107,159],"public":[24],"health":[25],"and":[26,72,125,136,176,190],"safety.":[27],"One":[28],"the":[30,45,123,154,181],"virulent":[32],"determinants":[33],"capsular":[38],"polysaccharide":[39],"or":[40],"K":[41,83,104,185,198],"antigen":[42],"located":[43],"on":[44],"bacterial":[46],"outer":[47],"membrane":[48],"surface,":[49],"which":[50,112],"potential":[53],"drug":[54],"&":[55],"vaccine":[56],"target.":[57],"It":[58],"plays":[59],"key":[61],"role":[62],"in":[63,117],"host-pathogen":[64],"interactions":[65],"well":[67],"host":[69],"immune":[70],"evasion":[71],"thus,":[73,191],"mandates":[74],"detailed":[75],"structural":[76,80],"information.":[77],"Nonetheless,":[78],"acquiring":[79],"information":[81,194],"antigens":[84,105,186],"not":[86],"straightforward":[87],"due":[88],"their":[90,118,126,133],"innate":[91],"enormous":[92],"conformational":[93],"flexibility.":[94],"Here,":[95],"we":[96,130],"have":[97,131],"developed":[98,137],"manually":[100],"curated":[101],"database":[102,151],"corresponding":[106],"various":[108],"E.":[109,161,196],"coli":[110,162,197],"serotypes,":[111],"differ":[113],"from":[114],"each":[115],"other":[116],"monosaccharide":[119],"composition,":[120],"linkage":[121],"between":[122],"monosaccharides":[124],"stereoisomeric":[127],"forms.":[128],"Subsequently,":[129],"modeled":[132],"3D":[134],"structures":[135],"an":[138],"organized":[139],"repository,":[140],"namely":[141],"EK3D":[142,178],"that":[143],"can":[144],"be":[145],"accessed":[146],"through":[147],"www.iith.ac.in/EK3D/.":[148],"Such":[149],"would":[152],"facilitate":[153],"development":[155],"antibacterial":[157],"drugs":[158,172],"combat":[160],"infections":[163],"it":[165],"has":[166],"evolved":[167],"against":[169],"2":[170],"namely,":[173],"third-generation":[174],"cephalosporins":[175],"fluoroquinolones.":[177],"also":[179],"enables":[180],"generation":[182],"polymeric":[184],"varying":[188],"lengths":[189],"provides":[192],"comprehensive":[193],"about":[195],"antigens.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2}],"updated_date":"2026-06-25T06:16:34.145877","created_date":"2016-06-24T00:00:00"}