{"id":"https://openalex.org/W2225562129","doi":"https://doi.org/10.1093/nar/gkv1283","title":"CancerResource\u2014updated database of cancer-relevant proteins, mutations and interacting drugs","display_name":"CancerResource\u2014updated database of cancer-relevant proteins, mutations and interacting drugs","publication_year":2015,"publication_date":"2015-11-20","ids":{"openalex":"https://openalex.org/W2225562129","doi":"https://doi.org/10.1093/nar/gkv1283","mag":"2225562129","pmid":"https://pubmed.ncbi.nlm.nih.gov/26590406"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkv1283","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1283","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D932/9483799/gkv1283.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/44/D1/D932/9483799/gkv1283.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060130832","display_name":"Bj\u00f6rn-Oliver Gohlke","orcid":"https://orcid.org/0000-0003-3094-1031"},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]},{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210103542","display_name":"German Cancer Society","ror":"https://ror.org/013z6ae41","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210103542"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bjoern-Oliver Gohlke","raw_affiliation_strings":["Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany","Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany","institution_ids":["https://openalex.org/I17937529","https://openalex.org/I4210103542","https://openalex.org/I223822909","https://openalex.org/I2802164966"]},{"raw_affiliation_string":"Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany","institution_ids":["https://openalex.org/I17937529","https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059328072","display_name":"Janette Nickel","orcid":null},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]},{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210103542","display_name":"German Cancer Society","ror":"https://ror.org/013z6ae41","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210103542"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Janette Nickel","raw_affiliation_strings":["Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany","German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany","Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany","institution_ids":["https://openalex.org/I17937529","https://openalex.org/I4210103542","https://openalex.org/I223822909","https://openalex.org/I2802164966"]},{"raw_affiliation_string":"German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany","institution_ids":["https://openalex.org/I17937529","https://openalex.org/I223822909"]},{"raw_affiliation_string":"Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000538220","display_name":"Raik Otto","orcid":"https://orcid.org/0000-0003-3644-743X"},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Raik Otto","raw_affiliation_strings":["Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090164972","display_name":"Mathias Dunkel","orcid":"https://orcid.org/0000-0002-6642-483X"},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mathias Dunkel","raw_affiliation_strings":["Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043414157","display_name":"Robert Prei\u00dfner","orcid":"https://orcid.org/0000-0002-2407-1087"},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]},{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Robert Preissner","raw_affiliation_strings":["Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany robert.preissner@charite.de","Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charit\u00e9 - University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany robert.preissner@charite.de","institution_ids":["https://openalex.org/I17937529","https://openalex.org/I223822909","https://openalex.org/I2802164966"]},{"raw_affiliation_string":"Charit\u00e9 \u2013 University Medicine Berlin, Structural Bioinformatics Group, Institute of Physiology & Experimental Clinical Research Center, Berlin 13125, Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany","institution_ids":["https://openalex.org/I17937529","https://openalex.org/I223822909"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":1.4158,"has_fulltext":true,"cited_by_count":41,"citation_normalized_percentile":{"value":0.80275964,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"44","issue":"D1","first_page":"D932","last_page":"D937"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.9958999752998352,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9954000115394592,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.912433385848999},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5250862836837769},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.48160549998283386},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.47821375727653503},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4451107084751129},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3517987132072449},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.33042263984680176},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.22434625029563904},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.06840714812278748}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.912433385848999},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5250862836837769},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.48160549998283386},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.47821375727653503},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4451107084751129},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3517987132072449},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.33042263984680176},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22434625029563904},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.06840714812278748}],"mesh":[{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1093/nar/gkv1283","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1283","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D932/9483799/gkv1283.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:26590406","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26590406","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:europepmc.org:3680823","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4702908","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:edoc.mdc-berlin.de:15198","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306400224","display_name":"MDC Repository (Max-Delbrueck-Center for Molecular Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:open-archive.highwire.org:nar:44/D1/D932","is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/44/D1/D932","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:refubium.fu-berlin.de:fub188/16309","is_oa":true,"landing_page_url":"https://refubium.fu-berlin.de/handle/fub188/16309","pdf_url":null,"source":{"id":"https://openalex.org/S4306402444","display_name":"Refubium (Universit\u00e4tsbibliothek der Freien Universit\u00e4t Berlin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I75951250","host_organization_name":"Freie Universit\u00e4t Berlin","host_organization_lineage":["https://openalex.org/I75951250"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Wissenschaftlicher Artikel"}],"best_oa_location":{"id":"doi:10.1093/nar/gkv1283","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1283","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D932/9483799/gkv1283.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6399999856948853,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G7085860440","display_name":null,"funder_award_id":"031A268B","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"},{"id":"https://openalex.org/G7349063869","display_name":null,"funder_award_id":"031A262C","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"}],"funders":[{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320327569","display_name":"Deutschen Konsortium f\u00fcr Translationale Krebsforschung","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2225562129.pdf","grobid_xml":"https://content.openalex.org/works/W2225562129.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1591649477","https://openalex.org/W1605923270","https://openalex.org/W1965856472","https://openalex.org/W1972587504","https://openalex.org/W1975875968","https://openalex.org/W1978817293","https://openalex.org/W1983248350","https://openalex.org/W1992442866","https://openalex.org/W2004879789","https://openalex.org/W2018518196","https://openalex.org/W2028236537","https://openalex.org/W2043398720","https://openalex.org/W2058389403","https://openalex.org/W2061623393","https://openalex.org/W2063280109","https://openalex.org/W2063961339","https://openalex.org/W2067256262","https://openalex.org/W2070171305","https://openalex.org/W2072305554","https://openalex.org/W2074370114","https://openalex.org/W2076295728","https://openalex.org/W2087312216","https://openalex.org/W2093602249","https://openalex.org/W2096729078","https://openalex.org/W2103196126","https://openalex.org/W2112366036","https://openalex.org/W2118151336","https://openalex.org/W2128542677","https://openalex.org/W2131848047","https://openalex.org/W2139994096","https://openalex.org/W2149372853","https://openalex.org/W2149441684","https://openalex.org/W2158394019","https://openalex.org/W2158564267","https://openalex.org/W2329659234","https://openalex.org/W4210799517","https://openalex.org/W6667569961","https://openalex.org/W6669842055"],"related_works":["https://openalex.org/W2003932708","https://openalex.org/W2284877871","https://openalex.org/W2138102289","https://openalex.org/W1967424056","https://openalex.org/W868043274","https://openalex.org/W2513523087","https://openalex.org/W1187916458","https://openalex.org/W2373861055","https://openalex.org/W2146849562","https://openalex.org/W2028961943"],"abstract_inverted_index":{"Here,":[0],"we":[1],"present":[2],"an":[3],"updated":[4],"version":[5],"of":[6,77,115,151,158,169],"CancerResource,":[7],"freely":[8],"available":[9,85],"without":[10],"registration":[11],"at":[12],"http://bioinformatics.charite.de/care.":[13],"With":[14],"upcoming":[15],"information":[16,79],"on":[17,31,40,60],"target":[18],"expression":[19,55,118,160],"and":[20,46,58,72,83,103,119,122,132,162],"mutations":[21],"in":[22,53,88],"patients'":[23],"tumors,":[24],"the":[25,89,113,126,149,167,184],"need":[26],"for":[27,107,189],"systems":[28],"supporting":[29,47,73],"decisions":[30],"individual":[32],"therapy":[33],"is":[34,38],"growing.":[35],"This":[36],"knowledge":[37],"based":[39],"numerous,":[41],"experimentally":[42],"validated":[43],"drug-target":[44,70,95,146],"interactions":[45,147],"analyses":[48],"such":[49],"as":[50,86],"measuring":[51],"changes":[52],"gene":[54],"using":[56],"microarrays":[57],"HTS-efforts":[59],"cell":[61,101,128,192],"lines.":[62,129],"To":[63],"enable":[64],"a":[65,75,141,190,197],"better":[66,142],"overview":[67,143],"about":[68,93,108,144],"similar":[69,195],"data":[71,106,121,164],"information,":[74],"series":[76],"novel":[78],"connections":[80],"are":[81,134],"established":[82],"made":[84],"described":[87],"following.":[90],"CancerResource":[91,111],"contains":[92],"91,000":[94],"relations,":[96],"more":[97],"than":[98],"2000":[99],"cancer":[100,191],"lines":[102],"drug":[104,172,187],"sensitivity":[105,173],"50,000":[109],"drugs.":[110],"enables":[112],"capability":[114],"uploading":[116],"external":[117],"mutation":[120],"comparing":[123],"them":[124],"to":[125,139,171,182,196],"database's":[127],"Target":[130],"genes":[131],"compounds":[133],"projected":[135],"onto":[136],"cancer-related":[137],"pathways":[138],"get":[140],"how":[145],"benefit":[148],"treatment":[150,188],"cancer.":[152],"Features":[153],"like":[154],"cellular":[155],"fingerprints":[156],"comprising":[157],"mutations,":[159],"values":[161],"drug-sensitivity":[163],"can":[165,178],"promote":[166],"understanding":[168],"genotype":[170],"associations.":[174],"Ultimately,":[175],"these":[176],"profiles":[177],"also":[179],"be":[180],"used":[181],"determine":[183],"most":[185,194],"effective":[186],"line":[193],"patient's":[198],"tumor":[199],"cells.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}