{"id":"https://openalex.org/W1943803206","doi":"https://doi.org/10.1093/nar/gkv1138","title":"Deciphering the mechanisms of developmental disorders: phenotype analysis of embryos from mutant mouse lines","display_name":"Deciphering the mechanisms of developmental disorders: phenotype analysis of embryos from mutant mouse lines","publication_year":2015,"publication_date":"2015-10-30","ids":{"openalex":"https://openalex.org/W1943803206","doi":"https://doi.org/10.1093/nar/gkv1138","mag":"1943803206","pmid":"https://pubmed.ncbi.nlm.nih.gov/26519470"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkv1138","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1138","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D855/9482641/gkv1138.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/44/D1/D855/9482641/gkv1138.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114378237","display_name":"Robert Wilson","orcid":"https://orcid.org/0000-0002-9407-5526"},"institutions":[{"id":"https://openalex.org/I2801081054","display_name":"The Francis Crick Institute","ror":"https://ror.org/04tnbqb63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert Wilson","raw_affiliation_strings":["The Francis Crick Institute Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW7 1AA, UK Robert.Wilson@crick.ac.uk","The Francis Crick Institute, Mill Hill Laboratory, the Ridgeway, Mill Hill, London NW7 1AA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Francis Crick Institute Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW7 1AA, UK Robert.Wilson@crick.ac.uk","institution_ids":["https://openalex.org/I2801081054"]},{"raw_affiliation_string":"The Francis Crick Institute, Mill Hill Laboratory, the Ridgeway, Mill Hill, London NW7 1AA, UK","institution_ids":["https://openalex.org/I2801081054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112285490","display_name":"Christina McGuire","orcid":null},"institutions":[{"id":"https://openalex.org/I2801081054","display_name":"The Francis Crick Institute","ror":"https://ror.org/04tnbqb63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christina McGuire","raw_affiliation_strings":["The Francis Crick Institute Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW7 1AA, UK","The Francis Crick Institute, Mill Hill Laboratory, the Ridgeway, Mill Hill, London NW7 1AA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Francis Crick Institute Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW7 1AA, UK","institution_ids":["https://openalex.org/I2801081054"]},{"raw_affiliation_string":"The Francis Crick Institute, Mill Hill Laboratory, the Ridgeway, Mill Hill, London NW7 1AA, UK","institution_ids":["https://openalex.org/I2801081054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032920346","display_name":"Timothy J. Mohun","orcid":"https://orcid.org/0000-0002-0216-0417"},"institutions":[{"id":"https://openalex.org/I2801081054","display_name":"The Francis Crick Institute","ror":"https://ror.org/04tnbqb63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Timothy Mohun","raw_affiliation_strings":["The Francis Crick Institute Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW7 1AA, UK","The Francis Crick Institute, Mill Hill Laboratory, the Ridgeway, Mill Hill, London NW7 1AA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Francis Crick Institute Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW7 1AA, UK","institution_ids":["https://openalex.org/I2801081054"]},{"raw_affiliation_string":"The Francis Crick Institute, Mill Hill Laboratory, the Ridgeway, Mill Hill, London NW7 1AA, UK","institution_ids":["https://openalex.org/I2801081054"]}]},{"author_position":"last","author":{"id":null,"display_name":"the DMDD project","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"the DMDD project","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":1.4779,"has_fulltext":true,"cited_by_count":51,"citation_normalized_percentile":{"value":0.815789,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"44","issue":"D1","first_page":"D855","last_page":"D861"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9883999824523926,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9883999824523926,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.9865000247955322,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9613999724388123,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8978655338287354},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.803202748298645},{"id":"https://openalex.org/keywords/embryo","display_name":"Embryo","score":0.7685121893882751},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5799345970153809},{"id":"https://openalex.org/keywords/mutant","display_name":"Mutant","score":0.5790171027183533},{"id":"https://openalex.org/keywords/embryonic-stem-cell","display_name":"Embryonic stem cell","score":0.5720523595809937},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.45211610198020935},{"id":"https://openalex.org/keywords/embryogenesis","display_name":"Embryogenesis","score":0.44876715540885925},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4375491142272949},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.37723031640052795},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3635736405849457},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.36008086800575256}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8978655338287354},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.803202748298645},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.7685121893882751},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5799345970153809},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.5790171027183533},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.5720523595809937},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.45211610198020935},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.44876715540885925},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4375491142272949},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.37723031640052795},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3635736405849457},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.36008086800575256}],"mesh":[{"descriptor_ui":"D000013","descriptor_name":"Congenital Abnormalities","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000013","descriptor_name":"Congenital Abnormalities","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000013","descriptor_name":"Congenital Abnormalities","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000013","descriptor_name":"Congenital Abnormalities","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D005804","descriptor_name":"Genes, Lethal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005804","descriptor_name":"Genes, Lethal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005804","descriptor_name":"Genes, Lethal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005804","descriptor_name":"Genes, Lethal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1093/nar/gkv1138","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1138","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D855/9482641/gkv1138.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:26519470","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26519470","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:kclpure.kcl.ac.uk:publications/7c8a7e3d-8f47-4c8d-a131-0d32db33c08a","is_oa":true,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/7c8a7e3d-8f47-4c8d-a131-0d32db33c08a","pdf_url":"https://kclpure.kcl.ac.uk/ws/files/57081208/Deciphering_the_mechanisms_HOUART_Accepted_10Jul2016_GOLD_VoR.pdf","source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wilson, R, McGuire, C, Mohun, T, Adams, D, Baldock, R, Bhattacharya, S, Collins, J, Fineberg, E, Firminger, L, Galli, A, Geyer, S, Grifiths, M, Hassan, A, Hemberger, M, Houart, C, Melvin, D, Prin, F, Ramirez-Solis, R, Reissig, L, Robertson, E, Rose, J, Schneider, J, Smith, J, Szumska, D, Tudor, C, Vernet, A, Weninger, W & White, J 2016, 'Deciphering the mechanisms of developmental disorders : Phenotype analysis of embryos from mutant mouse lines', Nucleic Acids Research, vol. 44, no. D1, pp. D855-D861. https://doi.org/10.1093/nar/gkv1138","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:europepmc.org:3680739","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4702824","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/12988475","is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Deciphering_the_mechanisms_of_developmental_disorders_phenotype_analysis_of_embryos_from_mutant_mouse_lines/12988475","pdf_url":null,"source":{"id":"https://openalex.org/S4306402621","display_name":"INDIGO (University of Illinois at Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39422238","host_organization_name":"University of Illinois Chicago","host_organization_lineage":["https://openalex.org/I39422238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:nar:44/D1/D855","is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/44/D1/D855","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1093/nar/gkv1138","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkv1138","pdf_url":"https://academic.oup.com/nar/article-pdf/44/D1/D855/9482641/gkv1138.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G161733502","display_name":"ePhenotype - Visual Analytics for Integrated Large Scale Gene-Expression and Phenotype Data","funder_award_id":"BB/N023307/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G6074043442","display_name":null,"funder_award_id":"10157","funder_id":"https://openalex.org/F4320312060","funder_display_name":"Francis Crick Institute"},{"id":"https://openalex.org/G6570681095","display_name":"Signalling pathways in cardiogenesis","funder_award_id":"RG/10/17/28553","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G6759749603","display_name":null,"funder_award_id":"BB/N023307/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G7670216049","display_name":"Deciphering the Mechanisms of Developmental Disorders (DMDD).","funder_award_id":"100160","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320312060","display_name":"Francis Crick Institute","ror":"https://ror.org/04tnbqb63"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319992","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1943803206.pdf","grobid_xml":"https://content.openalex.org/works/W1943803206.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1551890621","https://openalex.org/W1939775897","https://openalex.org/W2006719549","https://openalex.org/W2012896813","https://openalex.org/W2014946063","https://openalex.org/W2019993995","https://openalex.org/W2102702018","https://openalex.org/W2105823396","https://openalex.org/W2110663696","https://openalex.org/W2153759415","https://openalex.org/W2154331071"],"related_works":["https://openalex.org/W1969189734","https://openalex.org/W2377533390","https://openalex.org/W2382095633","https://openalex.org/W2129146900","https://openalex.org/W2126148372","https://openalex.org/W2267440929","https://openalex.org/W2360646261","https://openalex.org/W2350356125","https://openalex.org/W2383211881","https://openalex.org/W3165255536"],"abstract_inverted_index":{"The":[0,51,77],"Deciphering":[1],"the":[2,19,34,84,91,100,104,108,124,134],"Mechanisms":[3],"of":[4,36,39,56,73],"Developmental":[5],"Disorders":[6],"(DMDD)":[7],"consortium":[8],"is":[9,145],"a":[10,54,127,140],"research":[11],"programme":[12],"set":[13],"up":[14],"to":[15,65,103,111,122,132,147,151],"identify":[16,66],"genes":[17],"in":[18,27,68,117],"mouse,":[20],"which":[21],"if":[22],"mutated":[23],"(or":[24],"knocked-out)":[25],"result":[26],"embryonic":[28,74],"lethality":[29],"when":[30],"homozygous,":[31],"and":[32,49,62,70,83,129,139,149],"initiate":[33],"study":[35],"why":[37],"disruption":[38],"their":[40],"function":[41],"has":[42],"such":[43],"profound":[44],"effects":[45],"on":[46],"embryo":[47,69,109,138],"development":[48],"survival.":[50],"project":[52,92],"uses":[53],"combination":[55],"comprehensive":[57],"high":[58],"resolution":[59,116],"3D":[60],"imaging":[61],"tissue":[63],"histology":[64],"abnormalities":[67],"placental":[71],"structures":[72],"lethal":[75],"lines.":[76],"image":[78],"data":[79,110,135],"we":[80,98],"have":[81],"collected":[82],"phenotypes":[85],"scored":[86],"are":[87],"freely":[88],"available":[89],"through":[90],"website":[93],"(http://dmdd.org.uk).":[94],"In":[95],"this":[96],"article":[97],"describe":[99],"web":[101],"interface":[102],"images":[105],"that":[106],"allows":[107],"be":[112],"viewed":[113],"at":[114],"full":[115],"different":[118],"planes,":[119],"discuss":[120],"how":[121],"search":[123],"database":[125],"for":[126,136],"phenotype,":[128],"our":[130],"approach":[131],"organising":[133],"an":[137],"mutant":[141],"line":[142],"so":[143],"it":[144],"easy":[146],"comprehend":[148],"intuitive":[150],"navigate.":[152]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}