{"id":"https://openalex.org/W2103565574","doi":"https://doi.org/10.1093/nar/gku1086","title":"EHFPI: a database and analysis resource of essential host factors for pathogenic infection","display_name":"EHFPI: a database and analysis resource of essential host factors for pathogenic infection","publication_year":2014,"publication_date":"2014-11-20","ids":{"openalex":"https://openalex.org/W2103565574","doi":"https://doi.org/10.1093/nar/gku1086","mag":"2103565574","pmid":"https://pubmed.ncbi.nlm.nih.gov/25414353"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gku1086","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gku1086","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/nar/gku1086","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100355920","display_name":"Yang Liu","orcid":"https://orcid.org/0000-0002-5221-7725"},"institutions":[{"id":"https://openalex.org/I4210132047","display_name":"Beijing Radiation Center","ror":"https://ror.org/030t7nd77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210132047"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yang Liu","raw_affiliation_strings":["Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China","institution_ids":["https://openalex.org/I4210132047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055037581","display_name":"Dafei Xie","orcid":"https://orcid.org/0000-0002-4854-8986"},"institutions":[{"id":"https://openalex.org/I4210132047","display_name":"Beijing Radiation Center","ror":"https://ror.org/030t7nd77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210132047"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dafei Xie","raw_affiliation_strings":["Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China","institution_ids":["https://openalex.org/I4210132047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100611077","display_name":"Lu Han","orcid":"https://orcid.org/0000-0002-9842-2636"},"institutions":[{"id":"https://openalex.org/I4210132047","display_name":"Beijing Radiation Center","ror":"https://ror.org/030t7nd77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210132047"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lu Han","raw_affiliation_strings":["Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China","institution_ids":["https://openalex.org/I4210132047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018758426","display_name":"Hui Bai","orcid":"https://orcid.org/0000-0002-9013-7873"},"institutions":[{"id":"https://openalex.org/I4210160531","display_name":"Chinese People's Liberation Army","ror":"https://ror.org/05tf9r976","country_code":"CN","type":"funder","lineage":["https://openalex.org/I4210160531"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Bai","raw_affiliation_strings":["Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China No. 451 Hospital of Chinese People's Liberation Army, Xi'an 710054, China huibai13@hotmail.com","Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China No. 451 Hospital of Chinese People's Liberation Army, Xi'an 710054, China"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China No. 451 Hospital of Chinese People's Liberation Army, Xi'an 710054, China huibai13@hotmail.com","institution_ids":[]},{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China No. 451 Hospital of Chinese People's Liberation Army, Xi'an 710054, China","institution_ids":["https://openalex.org/I4210160531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100325907","display_name":"Fei Li","orcid":"https://orcid.org/0000-0003-4895-7330"},"institutions":[{"id":"https://openalex.org/I4210132047","display_name":"Beijing Radiation Center","ror":"https://ror.org/030t7nd77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210132047"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fei Li","raw_affiliation_strings":["Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China lifei@bmi.ac.cn","Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China lifei@bmi.ac.cn","institution_ids":[]},{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China","institution_ids":["https://openalex.org/I4210132047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101645609","display_name":"Shengqi Wang","orcid":"https://orcid.org/0000-0001-8100-7295"},"institutions":[{"id":"https://openalex.org/I4210132047","display_name":"Beijing Radiation Center","ror":"https://ror.org/030t7nd77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210132047"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengqi Wang","raw_affiliation_strings":["Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China","institution_ids":["https://openalex.org/I4210132047"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045958734","display_name":"Xiaochen Bo","orcid":"https://orcid.org/0000-0003-1911-7922"},"institutions":[{"id":"https://openalex.org/I4210132047","display_name":"Beijing Radiation Center","ror":"https://ror.org/030t7nd77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210132047"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaochen Bo","raw_affiliation_strings":["Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China boxc@bmi.ac.cn","Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China boxc@bmi.ac.cn","institution_ids":[]},{"raw_affiliation_string":"Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, P.R.China","institution_ids":["https://openalex.org/I4210132047"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5100355920"],"corresponding_institution_ids":["https://openalex.org/I4210132047"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":0.5704,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.67724622,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"43","issue":"D1","first_page":"D946","last_page":"D955"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9902999997138977,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9872000217437744,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7993161678314209},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5950736999511719},{"id":"https://openalex.org/keywords/host","display_name":"Host (biology)","score":0.5409456491470337},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.48305946588516235},{"id":"https://openalex.org/keywords/gene-co-expression-network","display_name":"Gene co-expression network","score":0.4818757474422455},{"id":"https://openalex.org/keywords/pathogen","display_name":"Pathogen","score":0.4319508373737335},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.34457913041114807},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3345469832420349},{"id":"https://openalex.org/keywords/gene-ontology","display_name":"Gene ontology","score":0.1565295159816742},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.13810572028160095}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7993161678314209},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5950736999511719},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.5409456491470337},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.48305946588516235},{"id":"https://openalex.org/C2778022302","wikidata":"https://www.wikidata.org/wiki/Q18207329","display_name":"Gene co-expression network","level":5,"score":0.4818757474422455},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.4319508373737335},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34457913041114807},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3345469832420349},{"id":"https://openalex.org/C2987395477","wikidata":"https://www.wikidata.org/wiki/Q135085","display_name":"Gene ontology","level":4,"score":0.1565295159816742},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.13810572028160095}],"mesh":[{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009980","descriptor_name":"Influenza A virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009980","descriptor_name":"Influenza A virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009980","descriptor_name":"Influenza A virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1093/nar/gku1086","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gku1086","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:25414353","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25414353","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1017.7934","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1017.7934","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://nar.oxfordjournals.org/content/early/2014/11/20/nar.gku1086.full.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1025.536","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1025.536","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://nar.oxfordjournals.org/content/43/D1/D946.full.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.805.3025","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.805.3025","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/94/2d/gku1086.PMC4383917.pdf","raw_type":"text"},{"id":"pmh:oai:europepmc.org:3354863","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4383917","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gku1086","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gku1086","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1668954519","https://openalex.org/W1972397861","https://openalex.org/W1981215030","https://openalex.org/W1989277387","https://openalex.org/W1991809658","https://openalex.org/W1995535465","https://openalex.org/W1999001280","https://openalex.org/W2011882057","https://openalex.org/W2015698698","https://openalex.org/W2018518196","https://openalex.org/W2022472106","https://openalex.org/W2022687771","https://openalex.org/W2029044166","https://openalex.org/W2068880841","https://openalex.org/W2069389008","https://openalex.org/W2070924692","https://openalex.org/W2073006669","https://openalex.org/W2074410038","https://openalex.org/W2077562263","https://openalex.org/W2081526068","https://openalex.org/W2094757405","https://openalex.org/W2096561521","https://openalex.org/W2105039688","https://openalex.org/W2108539496","https://openalex.org/W2109129937","https://openalex.org/W2113140044","https://openalex.org/W2113474003","https://openalex.org/W2116868464","https://openalex.org/W2122863289","https://openalex.org/W2123724865","https://openalex.org/W2124570615","https://openalex.org/W2133177319","https://openalex.org/W2133465414","https://openalex.org/W2160103276","https://openalex.org/W4237335579","https://openalex.org/W6667730856"],"related_works":["https://openalex.org/W2157598224","https://openalex.org/W2117112636","https://openalex.org/W2001981265","https://openalex.org/W2317560666","https://openalex.org/W2895015313","https://openalex.org/W2014134454","https://openalex.org/W2091398531","https://openalex.org/W2343234619","https://openalex.org/W3173815060","https://openalex.org/W4286497165"],"abstract_inverted_index":{"High-throughput":[0],"screening":[1],"and":[2,56,73,96,118,145,161,169,176,181,193],"computational":[3],"technology":[4],"has":[5],"greatly":[6],"changed":[7],"the":[8,48,125,129,178,188],"face":[9],"of":[10,29,51,80,84,128,132,139,158,163,190],"microbiology":[11],"in":[12,136],"better":[13],"understanding":[14,127],"pathogen-host":[15],"interactions.":[16],"Genome-wide":[17],"RNA":[18],"interference":[19],"(RNAi)":[20],"screens":[21],"have":[22],"given":[23],"rise":[24],"to":[25,185],"a":[26,52,78],"new":[27],"class":[28],"host":[30],"genes":[31,83],"designated":[32],"as":[33,135],"Essential":[34],"Host":[35,61],"Factors":[36,62],"(EHFs),":[37],"whose":[38],"knockdown":[39],"effects":[40],"significantly":[41],"influence":[42],"pathogenic":[43,88],"infections.":[44],"Therefore,":[45],"we":[46],"present":[47],"first":[49],"release":[50],"manually-curated":[53],"bioinformatics":[54],"database":[55],"analysis":[57,98,165],"resource":[58],"EHFPI":[59,67,91,148,167],"(Essential":[60],"for":[63,77,195],"Pathogenic":[64],"Infection,":[65],"http://biotech.bmi.ac.cn/ehfpi).":[66],"captures":[68],"detailed":[69],"article,":[70],"screen,":[71],"pathogen":[72],"phenotype":[74],"annotation":[75],"information":[76],"total":[79],"4634":[81],"EHF":[82,101,133,159],"25":[85],"clinically":[86],"important":[87],"species.":[89],"Notably,":[90],"also":[92],"provides":[93,151],"six":[94],"powerful":[95],"data-integrative":[97],"tools,":[99],"i.e.":[100],"Overlap":[102],"Analysis,":[103,106,109,114,122],"EHF-pathogen":[104],"Network":[105],"Gene":[107,121],"Enrichment":[108],"Pathogen":[110],"Interacting":[111],"Proteins":[112],"(PIPs)":[113],"Drug":[115],"Target":[116],"Analysis":[117],"GWAS":[119],"Candidate":[120],"which":[123],"advance":[124],"comprehensive":[126],"biological":[130],"roles":[131],"genes,":[134],"diverse":[137],"perspectives":[138],"protein-protein":[140],"interaction":[141],"network,":[142],"drug":[143],"targets":[144],"diseases/traits.":[146],"The":[147],"web":[149],"interface":[150],"appropriate":[152],"tools":[153,170],"that":[154],"allow":[155],"efficient":[156],"query":[157],"data":[160,168],"visualization":[162],"custom-made":[164],"results.":[166],"shall":[171],"keep":[172],"available":[173],"without":[174],"charge":[175],"serve":[177],"microbiology,":[179],"biomedicine":[180],"pharmaceutics":[182],"research":[183],"communities,":[184],"finally":[186],"facilitate":[187],"development":[189],"diagnostics,":[191],"prophylactics":[192],"therapeutics":[194],"human":[196],"pathogens.":[197]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":1}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}