{"id":"https://openalex.org/W2077912217","doi":"https://doi.org/10.1093/nar/gkt460","title":"SPACER: server for predicting allosteric communication and effects of regulation","display_name":"SPACER: server for predicting allosteric communication and effects of regulation","publication_year":2013,"publication_date":"2013-05-21","ids":{"openalex":"https://openalex.org/W2077912217","doi":"https://doi.org/10.1093/nar/gkt460","mag":"2077912217","pmid":"https://pubmed.ncbi.nlm.nih.gov/23737445"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkt460","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkt460","pdf_url":"https://academic.oup.com/nar/article-pdf/41/W1/W266/3869513/gkt460.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/41/W1/W266/3869513/gkt460.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075644443","display_name":"Alexander Goncearenco","orcid":"https://orcid.org/0000-0002-9738-7146"},"institutions":[{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Alexander Goncearenco","raw_affiliation_strings":["Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway","institution_ids":["https://openalex.org/I4432739"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060577157","display_name":"Simon Mitternacht","orcid":"https://orcid.org/0000-0002-4699-9054"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO","SG"],"is_corresponding":false,"raw_author_name":"Simon Mitternacht","raw_affiliation_strings":["Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","Agency for Science, Technology and Research, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"Agency for Science, Technology and Research, Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045310460","display_name":"Taipang Yong","orcid":null},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO","SG"],"is_corresponding":false,"raw_author_name":"Taipang Yong","raw_affiliation_strings":["Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","Agency for Science, Technology and Research, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"Agency for Science, Technology and Research, Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074249721","display_name":"Birgit Eisenhaber","orcid":"https://orcid.org/0000-0002-2910-7384"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO","SG"],"is_corresponding":false,"raw_author_name":"Birgit Eisenhaber","raw_affiliation_strings":["Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","Agency for Science, Technology and Research, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"Agency for Science, Technology and Research, Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007579711","display_name":"Frank Eisenhaber","orcid":"https://orcid.org/0000-0002-9599-5420"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO","SG"],"is_corresponding":true,"raw_author_name":"Frank Eisenhaber","raw_affiliation_strings":["Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","Agency for Science, Technology and Research, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"Agency for Science, Technology and Research, Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033504184","display_name":"Igor N. Berezovsky","orcid":"https://orcid.org/0000-0002-3315-8483"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO","SG"],"is_corresponding":false,"raw_author_name":"Igor N. Berezovsky","raw_affiliation_strings":["Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","Agency for Science, Technology and Research, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Unit and Department of Informatics, University of Bergen, Bergen 5020, Norway, 2 University Library, University of Bergen, Bergen 5020, Norway, 3 Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore, 4 Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive, 117597, Singapore, 5 School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553, Singapore and 6 Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"Agency for Science, Technology and Research, Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5007579711"],"corresponding_institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4432739"],"apc_list":{"value":3992,"currency":"USD","value_usd":3992},"apc_paid":{"value":3992,"currency":"USD","value_usd":3992},"fwci":9.3075,"has_fulltext":true,"cited_by_count":103,"citation_normalized_percentile":{"value":0.98458478,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"41","issue":"W1","first_page":"W266","last_page":"W272"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allosteric-regulation","display_name":"Allosteric regulation","score":0.9799396395683289},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6917095184326172},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.6591887474060059},{"id":"https://openalex.org/keywords/effector","display_name":"Effector","score":0.5984989404678345},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5536667108535767},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.35028183460235596},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16562104225158691},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.1428043246269226},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.11681082844734192}],"concepts":[{"id":"https://openalex.org/C166342909","wikidata":"https://www.wikidata.org/wiki/Q845326","display_name":"Allosteric regulation","level":3,"score":0.9799396395683289},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6917095184326172},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.6591887474060059},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.5984989404678345},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5536667108535767},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35028183460235596},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16562104225158691},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.1428043246269226},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.11681082844734192}],"mesh":[{"descriptor_ui":"D000494","descriptor_name":"Allosteric Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000494","descriptor_name":"Allosteric Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000494","descriptor_name":"Allosteric Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000495","descriptor_name":"Allosteric Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000495","descriptor_name":"Allosteric Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000495","descriptor_name":"Allosteric Site","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/nar/gkt460","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkt460","pdf_url":"https://academic.oup.com/nar/article-pdf/41/W1/W266/3869513/gkt460.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:23737445","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23737445","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2686057","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3692057","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:bora.uib.no:1956/12050","is_oa":true,"landing_page_url":"https://hdl.handle.net/1956/12050","pdf_url":null,"source":{"id":"https://openalex.org/S4306400085","display_name":"Bergen Open Research Archive (BORA) (University of Bergen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4432739","host_organization_name":"University of Bergen","host_organization_lineage":["https://openalex.org/I4432739"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/other"}],"best_oa_location":{"id":"doi:10.1093/nar/gkt460","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkt460","pdf_url":"https://academic.oup.com/nar/article-pdf/41/W1/W266/3869513/gkt460.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323299","display_name":"Norges Forskningsr\u00e5d","ror":"https://ror.org/00epmv149"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2077912217.pdf","grobid_xml":"https://content.openalex.org/works/W2077912217.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1989563793","https://openalex.org/W1998093640","https://openalex.org/W2005392755","https://openalex.org/W2011305816","https://openalex.org/W2011669324","https://openalex.org/W2027309027","https://openalex.org/W2035503835","https://openalex.org/W2044195587","https://openalex.org/W2049661341","https://openalex.org/W2049682677","https://openalex.org/W2055823413","https://openalex.org/W2084915350","https://openalex.org/W2096929343","https://openalex.org/W2097412382","https://openalex.org/W2100612868","https://openalex.org/W2115152262","https://openalex.org/W2115928493","https://openalex.org/W2123681603","https://openalex.org/W2130479394","https://openalex.org/W2158528359","https://openalex.org/W2159327390"],"related_works":["https://openalex.org/W2082860237","https://openalex.org/W2046450796","https://openalex.org/W2939998722","https://openalex.org/W2169750653","https://openalex.org/W2195592873","https://openalex.org/W1971782741","https://openalex.org/W3005062988","https://openalex.org/W2119695867","https://openalex.org/W2075777827","https://openalex.org/W2153919606"],"abstract_inverted_index":{"The":[0,56,103],"SPACER":[1,21],"server":[2,57,97,104],"provides":[3],"an":[4],"interactive":[5],"framework":[6],"for":[7,79,91],"exploring":[8],"allosteric":[9,60,92],"communication":[10,67],"in":[11,85],"proteins":[12],"with":[13],"different":[14],"sizes,":[15],"degrees":[16],"of":[17,32,48],"oligomerization":[18],"and":[19,38,62,71],"function.":[20],"uses":[22],"recently":[23],"developed":[24],"theoretical":[25],"concepts":[26],"based":[27],"on":[28,51],"the":[29,46,52,69,96],"thermodynamic":[30],"view":[31],"allostery.":[33],"It":[34,74],"proposes":[35],"easily":[36],"tractable":[37],"meaningful":[39],"measures":[40],"that":[41],"allow":[42],"users":[43,64],"to":[44,65,77],"analyze":[45],"effect":[47],"ligand":[49],"binding":[50,83],"intrinsic":[53],"protein":[54],"dynamics.":[55],"shows":[58],"potential":[59,81],"sites":[61,84],"allows":[63],"explore":[66],"between":[68],"regulatory":[70],"functional":[72],"sites.":[73],"is":[75,105],"possible":[76],"explore,":[78],"instance,":[80],"effector":[82],"a":[86,100],"given":[87],"structure":[88],"as":[89],"targets":[90],"drugs.":[93],"As":[94],"input,":[95],"only":[98],"requires":[99],"single":[101],"structure.":[102],"freely":[106],"available":[107],"at":[108],"http://allostery.bii.a-star.edu.sg/.":[109]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}