{"id":"https://openalex.org/W2159065634","doi":"https://doi.org/10.1093/nar/gkr1169","title":"DiseaseMeth: a human disease methylation database","display_name":"DiseaseMeth: a human disease methylation database","publication_year":2011,"publication_date":"2011-12-01","ids":{"openalex":"https://openalex.org/W2159065634","doi":"https://doi.org/10.1093/nar/gkr1169","mag":"2159065634","pmid":"https://pubmed.ncbi.nlm.nih.gov/22135302"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkr1169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkr1169","pdf_url":"https://academic.oup.com/nar/article-pdf/40/D1/D1030/9480345/gkr1169.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/40/D1/D1030/9480345/gkr1169.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113683918","display_name":"Jie Lv","orcid":"https://orcid.org/0000-0003-2329-4817"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"J. Lv","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045576282","display_name":"Hongbo Liu","orcid":"https://orcid.org/0000-0002-0733-8616"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"H. Liu","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083159278","display_name":"Jianzhong Su","orcid":"https://orcid.org/0000-0002-1172-7411"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"J. Su","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060314863","display_name":"Ximei Wu","orcid":"https://orcid.org/0000-0002-3316-893X"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"X. Wu","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045576282","display_name":"Hongbo Liu","orcid":"https://orcid.org/0000-0002-0733-8616"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"H. Liu","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023885825","display_name":"Bo Li","orcid":"https://orcid.org/0000-0003-4905-2744"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"B. Li","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052869072","display_name":"Xue Xiao","orcid":"https://orcid.org/0000-0003-1666-3813"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"X. Xiao","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100321352","display_name":"Fang Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"F. Wang","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100638546","display_name":"Qiong Wu","orcid":"https://orcid.org/0000-0003-3305-6652"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Q. Wu","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100386229","display_name":"Ying Zhang","orcid":"https://orcid.org/0000-0003-2194-7116"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Y. Zhang","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081 and 2State Key Laboratory of Urban Water Resource and Environment, Department of Life Science and Engineering, Harbin Institute of Technology, Harbin 150001, China","institution_ids":["https://openalex.org/I204983213","https://openalex.org/I156144747"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5100386229","https://openalex.org/A5100638546"],"corresponding_institution_ids":["https://openalex.org/I156144747","https://openalex.org/I204983213"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":3.7254,"has_fulltext":true,"cited_by_count":99,"citation_normalized_percentile":{"value":0.94144865,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"40","issue":"D1","first_page":"D1030","last_page":"D1035"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11928","display_name":"Genetic Syndromes and Imprinting","score":0.994700014591217,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.853628396987915},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8210873007774353},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.7501765489578247},{"id":"https://openalex.org/keywords/epigenetics","display_name":"Epigenetics","score":0.6343212127685547},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5685428380966187},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5364540219306946},{"id":"https://openalex.org/keywords/human-genome","display_name":"Human genome","score":0.5088394284248352},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.4887709319591522},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.4241673946380615},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4055935740470886},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.23536282777786255}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.853628396987915},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8210873007774353},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.7501765489578247},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6343212127685547},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5685428380966187},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5364540219306946},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.5088394284248352},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4887709319591522},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4241673946380615},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4055935740470886},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.23536282777786255},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/nar/gkr1169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkr1169","pdf_url":"https://academic.oup.com/nar/article-pdf/40/D1/D1030/9480345/gkr1169.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:22135302","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22135302","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:open-archive.highwire.org:nar:40/D1/D1030","is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/40/D1/D1030","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:pubmedcentral.nih.gov:3245164","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3245164","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkr1169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkr1169","pdf_url":"https://academic.oup.com/nar/article-pdf/40/D1/D1030/9480345/gkr1169.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8092251667","display_name":"mir-341\u3001mir-1188\u3001mir-370\u5728\u5c0f\u9f20\u53d1\u80b2\u4e2d\u7684\u8868\u8fbe\u4e0e\u8c03\u63a7\u673a\u5236\u7684\u7814\u7a76","funder_award_id":"30971645","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323085","display_name":"Natural Science Foundation of Heilongjiang Province","ror":null},{"id":"https://openalex.org/F4320327002","display_name":"State Key Laboratory of Urban Water Resource and Environment","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2159065634.pdf","grobid_xml":"https://content.openalex.org/works/W2159065634.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1965262464","https://openalex.org/W1974440717","https://openalex.org/W1975224807","https://openalex.org/W1980664975","https://openalex.org/W1991959431","https://openalex.org/W2004078197","https://openalex.org/W2009940298","https://openalex.org/W2010768718","https://openalex.org/W2016105151","https://openalex.org/W2029197798","https://openalex.org/W2033102369","https://openalex.org/W2042545888","https://openalex.org/W2043053726","https://openalex.org/W2043147472","https://openalex.org/W2047149866","https://openalex.org/W2064172549","https://openalex.org/W2078497756","https://openalex.org/W2078617491","https://openalex.org/W2079784129","https://openalex.org/W2095718447","https://openalex.org/W2096083625","https://openalex.org/W2106561340","https://openalex.org/W2115023583","https://openalex.org/W2117996813","https://openalex.org/W2123699903","https://openalex.org/W2127640118","https://openalex.org/W2132894713","https://openalex.org/W2139031446","https://openalex.org/W2141611532","https://openalex.org/W2142257318","https://openalex.org/W2145483405","https://openalex.org/W2148064779","https://openalex.org/W2160019289","https://openalex.org/W2486820350"],"related_works":["https://openalex.org/W2214376880","https://openalex.org/W3212149434","https://openalex.org/W2073893804","https://openalex.org/W2902329290","https://openalex.org/W2052355316","https://openalex.org/W2128056428","https://openalex.org/W2046964473","https://openalex.org/W2107880877","https://openalex.org/W2151182744","https://openalex.org/W2024490794"],"abstract_inverted_index":{"DNA":[0,30,57,84],"methylation":[1,31,58,71,85,121,154],"is":[2,52,76],"an":[3],"important":[4],"epigenetic":[5],"modification":[6],"for":[7,161,170],"genomic":[8],"regulation":[9],"in":[10,18],"higher":[11],"organisms":[12],"that":[13],"plays":[14],"a":[15,55,68,103,128],"crucial":[16],"role":[17],"the":[19,43,77,119,178],"initiation":[20],"and":[21,27,36,80,97,111,132,147,163,177],"progression":[22],"of":[23,29,45,60,83,106,123,130,173,180],"diseases.":[24,62,90],"The":[25,115],"integration":[26],"mining":[28],"data":[32,86,100,122,136,155],"by":[33],"methylation-specific":[34],"PCR":[35],"genome-wide":[37],"profiling":[38],"technology":[39],"could":[40],"greatly":[41],"assist":[42],"discovery":[44],"novel":[46],"candidate":[47],"disease":[48,70,148,162],"biomarkers.":[49],"However,":[50],"this":[51],"difficult":[53],"without":[54],"comprehensive":[56],"repository":[59],"human":[61,69,125],"Therefore,":[63],"we":[64],"have":[65,108],"developed":[66],"DiseaseMeth,":[67],"database":[72],"(http://bioinfo.hrbmu.edu.cn/diseasemeth).":[73],"Its":[74],"focus":[75],"efficient":[78],"storage":[79],"statistical":[81],"analysis":[82,160],"sets":[87,101],"from":[88,93,102,127],"various":[89],"Experimental":[91],"information":[92],"over":[94],"14,000":[95],"entries":[96],"175":[98],"high-throughput":[99],"wide":[104],"number":[105],"sources":[107],"been":[109],"collected":[110],"incorporated":[112],"into":[113],"DiseaseMeth.":[114],"latest":[116],"release":[117],"incorporates":[118],"gene-centric":[120],"72":[124],"diseases":[126],"variety":[129],"technologies":[131],"platforms.":[133],"To":[134],"facilitate":[135],"extraction,":[137],"DiseaseMeth":[138,150],"supports":[139],"multiple":[140],"search":[141],"options":[142],"such":[143],"as":[144],"gene":[145,153],"ID":[146],"name.":[149],"provides":[151],"integrated":[152],"based":[156],"on":[157],"cross-data":[158],"set":[159],"normal":[164],"samples.":[165],"These":[166],"can":[167],"be":[168],"used":[169],"in-depth":[171],"identification":[172],"differentially":[174],"methylated":[175],"genes":[176],"investigation":[179],"gene-disease":[181],"relationship.":[182]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":7}],"updated_date":"2026-06-06T09:05:17.133730","created_date":"2025-10-10T00:00:00"}
