{"id":"https://openalex.org/W2140665097","doi":"https://doi.org/10.1093/nar/gkr1051","title":"The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons","display_name":"The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons","publication_year":2011,"publication_date":"2011-11-24","ids":{"openalex":"https://openalex.org/W2140665097","doi":"https://doi.org/10.1093/nar/gkr1051","mag":"2140665097","pmid":"https://pubmed.ncbi.nlm.nih.gov/22121217"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkr1051","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkr1051","pdf_url":"https://academic.oup.com/nar/article-pdf/40/D1/D984/16954376/gkr1051.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/40/D1/D984/16954376/gkr1051.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110721438","display_name":"Shannan J. Ho Sui","orcid":null},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shannan J. Ho Sui","raw_affiliation_strings":["Department of Biostatistics, HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, USA. shosui@hsph.harvard.edu","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, USA. shosui@hsph.harvard.edu","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108079055","display_name":"Kimberly Begley","orcid":"https://orcid.org/0000-0002-1642-7493"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly Begley","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082039892","display_name":"Dorothy Reilly","orcid":"https://orcid.org/0000-0002-6677-3132"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dorothy Reilly","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043278195","display_name":"Brad Chapman","orcid":"https://orcid.org/0000-0002-3026-1856"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brad Chapman","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110007681","display_name":"Ray McGovern","orcid":null},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ray McGovern","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007758000","display_name":"Philippe Rocca-Sera","orcid":null},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philippe Rocca-Sera","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075052652","display_name":"Eamonn Maguire","orcid":"https://orcid.org/0000-0002-7277-7834"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eamonn Maguire","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002314622","display_name":"Gabriel Altschuler","orcid":"https://orcid.org/0000-0001-7981-7205"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabriel M. Altschuler","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037639207","display_name":"Terah A. A. Hansen","orcid":null},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terah A. A. Hansen","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089003112","display_name":"Ramakrishna Sompallae","orcid":"https://orcid.org/0000-0002-2948-8068"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ramakrishna Sompallae","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016322483","display_name":"Andrei V. Krivtsov","orcid":"https://orcid.org/0000-0002-5511-1686"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrei Krivtsov","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055619783","display_name":"Ramesh A. Shivdasani","orcid":"https://orcid.org/0000-0002-2828-1727"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ramesh A. Shivdasani","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012956545","display_name":"Scott A. Armstrong","orcid":"https://orcid.org/0000-0002-9099-4728"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott A. Armstrong","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082180580","display_name":"Aed\u00edn C. Culhane","orcid":"https://orcid.org/0000-0002-1395-9734"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aed\u00edn C. Culhane","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113699019","display_name":"Mick Correll","orcid":null},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mick Correll","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008806860","display_name":"Susanna\u2010Assunta Sansone","orcid":"https://orcid.org/0000-0001-5306-5690"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susanna-Assunta Sansone","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080048082","display_name":"Oliver Hofmann","orcid":"https://orcid.org/0000-0002-7738-1513"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oliver Hofmann","raw_affiliation_strings":["Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, 2HSPH Bioinformatics Core, Harvard School of Public Health, Boston, MA, 3Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA, USA, 4Oxford e-Research Centre, University of Oxford, UK, 5Department of Pediatric Oncology, Children's Hospital, 6Dana Farber Cancer Institute, and Harvard Medical School, Boston, 7Harvard Stem Cell Institute, Cambridge, 8Department of Biostatistics, Dana Farber Cancer Institute and 9Center for Cancer Computational Biology, Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453","https://openalex.org/I4210157861","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051775367","display_name":"Yoshihide Hayashizaki","orcid":"https://orcid.org/0000-0002-8621-3271"},"institutions":[{"id":"https://openalex.org/I2801851002","display_name":"Harvard University Press","ror":"https://ror.org/006v7bf86","country_code":"US","type":"other","lineage":["https://openalex.org/I136199984","https://openalex.org/I2801851002"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Winston Hide","raw_affiliation_strings":["Harvard University, Cambridge, United States"],"affiliations":[{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I2801851002"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":18,"corresponding_author_ids":["https://openalex.org/A5110721438"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2801851002"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":2.5348,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.89379891,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"40","issue":"D1","first_page":"D984","last_page":"D991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7954502701759338},{"id":"https://openalex.org/keywords/stem-cell","display_name":"Stem cell","score":0.7565176486968994},{"id":"https://openalex.org/keywords/cancer-stem-cell","display_name":"Cancer stem cell","score":0.5719769597053528},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5603959560394287},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3800484538078308},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16856351494789124}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7954502701759338},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.7565176486968994},{"id":"https://openalex.org/C55427017","wikidata":"https://www.wikidata.org/wiki/Q1638475","display_name":"Cancer stem cell","level":3,"score":0.5719769597053528},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5603959560394287},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3800484538078308},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16856351494789124}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1093/nar/gkr1051","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkr1051","pdf_url":"https://academic.oup.com/nar/article-pdf/40/D1/D984/16954376/gkr1051.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:22121217","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22121217","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:jupiter.its.unimelb.edu.au:11343/259616","is_oa":true,"landing_page_url":"http://hdl.handle.net/11343/259616","pdf_url":"http://hdl.handle.net/11343/259616","source":{"id":"https://openalex.org/S4377196259","display_name":"Minerva Access (University of Melbourne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I165779595","host_organization_name":"The University of Melbourne","host_organization_lineage":["https://openalex.org/I165779595"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:dash.harvard.edu:1/8646706","is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:8646706","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:nar:40/D1/D984","is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/40/D1/D984","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:pubmedcentral.nih.gov:3245064","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3245064","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkr1051","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkr1051","pdf_url":"https://academic.oup.com/nar/article-pdf/40/D1/D984/16954376/gkr1051.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4099999964237213,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[{"id":"https://openalex.org/G412979241","display_name":null,"funder_award_id":"BB/I000771/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G651559499","display_name":null,"funder_award_id":"BB/I025840/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G7775520706","display_name":null,"funder_award_id":"BB/E025080/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320322725","display_name":"China Scholarship Council","ror":"https://ror.org/04atp4p48"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332616","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2140665097.pdf","grobid_xml":"https://content.openalex.org/works/W2140665097.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W142326508","https://openalex.org/W1583240815","https://openalex.org/W1757909678","https://openalex.org/W1991923868","https://openalex.org/W2010457001","https://openalex.org/W2010502047","https://openalex.org/W2010605118","https://openalex.org/W2019199359","https://openalex.org/W2035813402","https://openalex.org/W2060551076","https://openalex.org/W2066453373","https://openalex.org/W2073759231","https://openalex.org/W2102085111","https://openalex.org/W2112236191","https://openalex.org/W2119436534","https://openalex.org/W2120381403","https://openalex.org/W2123152121","https://openalex.org/W2124928212","https://openalex.org/W2129301079","https://openalex.org/W2130430745","https://openalex.org/W2136482257","https://openalex.org/W2140987848","https://openalex.org/W2141297584","https://openalex.org/W2162419299","https://openalex.org/W2168546553","https://openalex.org/W6634936471"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W2013243191","https://openalex.org/W2150479858"],"abstract_inverted_index":{"Mounting":[0],"evidence":[1],"suggests":[2],"that":[3,52],"malignant":[4],"tumors":[5],"are":[6,36,53],"initiated":[7],"and":[8,31,55,91,98,110,118,130,138,146,176,183],"maintained":[9],"by":[10,42],"a":[11,43,122,159],"subpopulation":[12],"of":[13,22,28,49,73],"cancerous":[14],"cells":[15,60],"with":[16,164],"biological":[17],"properties":[18],"similar":[19],"to":[20,45,78,87,120],"those":[21],"normal":[23],"stem":[24,59,112],"cells.":[25],"However,":[26],"descriptions":[27],"stem-like":[29],"gene":[30,97,168],"pathway":[32,99],"signatures":[33,173],"in":[34,140,150,174,180,185],"cancers":[35],"inconsistent":[37],"across":[38,57],"experimental":[39,134],"systems.":[40],"Driven":[41],"need":[44],"improve":[46],"our":[47],"understanding":[48],"molecular":[50,172],"processes":[51],"common":[54],"unique":[56],"cancer":[58,111],"(CSCs),":[61],"we":[62],"have":[63],"developed":[64],"the":[65,79,96,141,151,181],"Stem":[66],"Cell":[67],"Discovery":[68],"Engine":[69],"(SCDE)-an":[70],"online":[71],"database":[72],"curated":[74,178],"CSC":[75,93],"experiments":[76,114,179],"coupled":[77],"Galaxy":[80,156],"analytical":[81],"framework.":[82],"The":[83,133,187],"SCDE":[84,182,188],"allows":[85],"users":[86],"consistently":[88],"describe,":[89],"share":[90],"compare":[92],"data":[94,152],"at":[95,191],"level.":[100],"Our":[101],"initial":[102],"focus":[103],"has":[104],"been":[105],"on":[106],"carefully":[107],"curating":[108],"tissue":[109],"cell-related":[113],"from":[115],"blood,":[116],"intestine":[117],"brain":[119],"create":[121],"high":[123],"quality":[124],"resource":[125],"containing":[126],"53":[127],"public":[128],"studies":[129],"1098":[131],"assays.":[132],"information":[135],"is":[136,189],"captured":[137],"stored":[139],"multi-omics":[142],"Investigation/Study/Assay":[143],"(ISA-Tab)":[144],"format":[145],"can":[147],"be":[148],"queried":[149],"repository.":[153],"A":[154],"linked":[155],"framework":[157],"provides":[158],"comprehensive,":[160],"flexible":[161],"environment":[162],"populated":[163],"novel":[165],"tools":[166],"for":[167],"list":[169],"comparisons":[170],"against":[171],"GeneSigDB":[175],"MSigDB,":[177],"pathways":[184],"WikiPathways.":[186],"available":[190],"http://discovery.hsci.harvard.edu.":[192]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":3}],"updated_date":"2026-03-07T13:37:22.277990","created_date":"2016-06-24T00:00:00"}