{"id":"https://openalex.org/W2005329278","doi":"https://doi.org/10.1093/nar/gkm948","title":"GLIDA: GPCR ligand database for chemical genomics drug discovery database and tools update","display_name":"GLIDA: GPCR ligand database for chemical genomics drug discovery database and tools update","publication_year":2007,"publication_date":"2007-11-06","ids":{"openalex":"https://openalex.org/W2005329278","doi":"https://doi.org/10.1093/nar/gkm948","mag":"2005329278","pmid":"https://pubmed.ncbi.nlm.nih.gov/17986454"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkm948","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkm948","pdf_url":"https://academic.oup.com/nar/article-pdf/36/suppl_1/D907/7634785/gkm948.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/36/suppl_1/D907/7634785/gkm948.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034233071","display_name":"Yusuke Okuno","orcid":"https://orcid.org/0000-0003-3139-9272"},"institutions":[{"id":"https://openalex.org/I25998863","display_name":"Kyoto Pharmaceutical University","ror":"https://ror.org/01ytgve10","country_code":"JP","type":"education","lineage":["https://openalex.org/I25998863"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Y. Okuno","raw_affiliation_strings":["Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan. okuno@pharm.kyoto-u.ac.jp","Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan"],"affiliations":[{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan. okuno@pharm.kyoto-u.ac.jp","institution_ids":["https://openalex.org/I25998863"]},{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053971924","display_name":"Akiko Tamon","orcid":null},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"A. Tamon","raw_affiliation_strings":["Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","Kyoto University, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000493551","display_name":"Hiroaki Yabuuchi","orcid":"https://orcid.org/0000-0002-7353-0956"},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Yabuuchi","raw_affiliation_strings":["Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","Kyoto University, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063578026","display_name":"Satoshi Niijima","orcid":null},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"S. Niijima","raw_affiliation_strings":["Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","Kyoto University, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032704674","display_name":"Yuki Minowa","orcid":null},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Minowa","raw_affiliation_strings":["Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","Kyoto University, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019139119","display_name":"K. Tonomura","orcid":null},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Tonomura","raw_affiliation_strings":["Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","Kyoto University, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082844597","display_name":"Ryo Kunimoto","orcid":"https://orcid.org/0000-0003-4895-9686"},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"R. Kunimoto","raw_affiliation_strings":["Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","Kyoto University, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074727448","display_name":"Chenchen Feng","orcid":"https://orcid.org/0000-0002-1854-356X"},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"C. Feng","raw_affiliation_strings":["Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","Kyoto University, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"Department of PharmacoInformatics, Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University and 2 Bio Science Group, IT Solution Div.1, Industry Solution Business Unit, Mitsui Knowledge Industry, Osaka city, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5034233071"],"corresponding_institution_ids":["https://openalex.org/I25998863"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":3.3618,"has_fulltext":true,"cited_by_count":135,"citation_normalized_percentile":{"value":0.92744174,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"36","issue":"Database","first_page":"D907","last_page":"D912"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/g-protein-coupled-receptor","display_name":"G protein-coupled receptor","score":0.7624657154083252},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.628998875617981},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5309184193611145},{"id":"https://openalex.org/keywords/chemical-database","display_name":"Chemical database","score":0.525032103061676},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.5033859610557556},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.4991459846496582},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4606722593307495},{"id":"https://openalex.org/keywords/data-integration","display_name":"Data integration","score":0.4367048740386963},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3994579017162323},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3827867805957794},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3592032194137573},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.275679349899292},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11180689930915833},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.09413409233093262},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.08895117044448853}],"concepts":[{"id":"https://openalex.org/C135285700","wikidata":"https://www.wikidata.org/wiki/Q38173","display_name":"G protein-coupled receptor","level":3,"score":0.7624657154083252},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.628998875617981},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5309184193611145},{"id":"https://openalex.org/C203394866","wikidata":"https://www.wikidata.org/wiki/Q2881060","display_name":"Chemical database","level":2,"score":0.525032103061676},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.5033859610557556},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.4991459846496582},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4606722593307495},{"id":"https://openalex.org/C72634772","wikidata":"https://www.wikidata.org/wiki/Q386824","display_name":"Data integration","level":2,"score":0.4367048740386963},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3994579017162323},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3827867805957794},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3592032194137573},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.275679349899292},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11180689930915833},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09413409233093262},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08895117044448853}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkm948","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkm948","pdf_url":"https://academic.oup.com/nar/article-pdf/36/suppl_1/D907/7634785/gkm948.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:17986454","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17986454","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:2238933","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2238933","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkm948","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkm948","pdf_url":"https://academic.oup.com/nar/article-pdf/36/suppl_1/D907/7634785/gkm948.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3236194794","display_name":null,"funder_award_id":"Grant-in-Aid","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6267471473","display_name":null,"funder_award_id":"Grant-in-Aid","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"},{"id":"https://openalex.org/G7482275571","display_name":null,"funder_award_id":"Ministry of Education, Culture, Sports, Science and Technology","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320315966","display_name":"Tateisi Science and Technology Foundation","ror":null},{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320321945","display_name":"Ministry of Health, Labour and Welfare","ror":"https://ror.org/03mwa7s65"},{"id":"https://openalex.org/F4320322617","display_name":"Okawa Foundation for Information and Telecommunications","ror":"https://ror.org/01enbtr31"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005329278.pdf","grobid_xml":"https://content.openalex.org/works/W2005329278.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1496826797","https://openalex.org/W1964213154","https://openalex.org/W1972678028","https://openalex.org/W1979537657","https://openalex.org/W2010519792","https://openalex.org/W2019074781","https://openalex.org/W2033388874","https://openalex.org/W2034994407","https://openalex.org/W2035753075","https://openalex.org/W2060851522","https://openalex.org/W2062224011","https://openalex.org/W2065699197","https://openalex.org/W2068440090","https://openalex.org/W2073110681","https://openalex.org/W2080211619","https://openalex.org/W2096525273","https://openalex.org/W2106607972","https://openalex.org/W2107580398","https://openalex.org/W2108934940","https://openalex.org/W2113221321","https://openalex.org/W2142237411","https://openalex.org/W2161062388","https://openalex.org/W2170146596","https://openalex.org/W2171756360","https://openalex.org/W4211083314","https://openalex.org/W4233523656","https://openalex.org/W4320800138"],"related_works":["https://openalex.org/W2609050007","https://openalex.org/W3011298851","https://openalex.org/W4224216382","https://openalex.org/W3195483439","https://openalex.org/W2444295418","https://openalex.org/W2169619547","https://openalex.org/W416861399","https://openalex.org/W4310603295","https://openalex.org/W1135792216","https://openalex.org/W2907597838"],"abstract_inverted_index":{"G-protein":[0],"coupled":[1],"receptors":[2],"(GPCRs)":[3],"represent":[4],"one":[5],"of":[6,11,32,78,98,166],"the":[7,30,53,76,103,116,129,167],"most":[8],"important":[9],"families":[10],"drug":[12,150,211],"targets":[13],"in":[14,69,75],"pharmaceutical":[15],"development.":[16],"GLIDA":[17,94,110,168,191],"is":[18,26,192],"a":[19,70,96,164],"public":[20],"GPCR-related":[21,210],"Chemical":[22,79,206],"Genomics":[23,80,207],"database":[24,169,178],"that":[25,199],"primarily":[27],"focused":[28],"on":[29,52,155],"integration":[31],"information":[33,51,59,86],"between":[34,43,132],"GPCRs":[35,44,104,119,133],"and":[36,45,105,134,148,170,173,188,209],"their":[37,46,107,123,143],"ligands.":[38,108],"It":[39],"provides":[40,163],"interaction":[41],"data":[42,63,180],"ligands,":[47,54,135],"along":[48],"with":[49,66,122],"chemical":[50,91],"as":[55,57],"well":[56],"biological":[58,89],"regarding":[60],"GPCRs.":[61],"These":[62],"are":[64],"connected":[65],"each":[67],"other":[68],"relational":[71],"database,":[72],"allowing":[73],"users":[74],"field":[77],"research":[81,208],"to":[82,177],"easily":[83],"retrieve":[84],"such":[85],"from":[87],"either":[88],"or":[90],"starting":[92],"points.":[93],"includes":[95],"variety":[97],"similarity":[99,185],"search":[100,186],"functions":[101],"for":[102,106,158,205],"Thus,":[109],"can":[111,137],"provide":[112],"correlation":[113,130],"maps":[114],"linking":[115],"searched":[117],"homologous":[118],"(or":[120,125],"ligands)":[121],"ligands":[124],"GPCRs).":[126],"By":[127],"analyzing":[128],"patterns":[131,147],"we":[136],"gain":[138],"more":[139],"detailed":[140],"knowledge":[141],"about":[142],"conserved":[144],"molecular":[145],"recognition":[146],"improve":[149],"design":[151],"efforts":[152],"by":[153],"focusing":[154],"inferred":[156],"candidates":[157],"GPCR-specific":[159],"drugs.":[160],"This":[161],"article":[162],"summary":[165],"user":[171],"facilities,":[172],"describes":[174],"recent":[175],"improvements":[176],"design,":[179],"contents,":[181],"ligand":[182],"classification":[183],"programs,":[184],"options":[187],"graphical":[189],"interfaces.":[190],"publicly":[193],"available":[194],"at":[195],"http://pharminfo.pharm.kyoto-u.ac.jp/services/glida/.":[196],"We":[197],"hope":[198],"it":[200],"will":[201],"prove":[202],"very":[203],"useful":[204],"discovery.":[212]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":14}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}