{"id":"https://openalex.org/W2110869427","doi":"https://doi.org/10.1093/nar/gkm423","title":"PIC: Protein Interactions Calculator","display_name":"PIC: Protein Interactions Calculator","publication_year":2007,"publication_date":"2007-05-08","ids":{"openalex":"https://openalex.org/W2110869427","doi":"https://doi.org/10.1093/nar/gkm423","mag":"2110869427","pmid":"https://pubmed.ncbi.nlm.nih.gov/17584791"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkm423","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkm423","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_2/W473/9587798/gkm423.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/35/suppl_2/W473/9587798/gkm423.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034922978","display_name":"Kirubakaran G. Tina","orcid":null},"institutions":[{"id":"https://openalex.org/I59270414","display_name":"Indian Institute of Science Bangalore","ror":"https://ror.org/04dese585","country_code":"IN","type":"education","lineage":["https://openalex.org/I59270414"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"K. G. Tina","raw_affiliation_strings":["Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India","Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012 (India)"],"affiliations":[{"raw_affiliation_string":"Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India","institution_ids":["https://openalex.org/I59270414"]},{"raw_affiliation_string":"Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012 (India)","institution_ids":["https://openalex.org/I59270414"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113555547","display_name":"R K Bhadra","orcid":null},"institutions":[{"id":"https://openalex.org/I59270414","display_name":"Indian Institute of Science Bangalore","ror":"https://ror.org/04dese585","country_code":"IN","type":"education","lineage":["https://openalex.org/I59270414"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R. Bhadra","raw_affiliation_strings":["Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India","Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012 (India)"],"affiliations":[{"raw_affiliation_string":"Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India","institution_ids":["https://openalex.org/I59270414"]},{"raw_affiliation_string":"Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012 (India)","institution_ids":["https://openalex.org/I59270414"]}]},{"author_position":"last","author":{"id":null,"display_name":"N. Srinivasan","orcid":null},"institutions":[{"id":"https://openalex.org/I59270414","display_name":"Indian Institute of Science Bangalore","ror":"https://ror.org/04dese585","country_code":"IN","type":"education","lineage":["https://openalex.org/I59270414"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"N. Srinivasan","raw_affiliation_strings":["Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012 (India)"],"affiliations":[{"raw_affiliation_string":"Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012 (India)","institution_ids":["https://openalex.org/I59270414"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5034922978"],"corresponding_institution_ids":["https://openalex.org/I59270414"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":7.1264,"has_fulltext":false,"cited_by_count":892,"citation_normalized_percentile":{"value":0.97953112,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"35","issue":"Web Server","first_page":"W473","last_page":"W476"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9891999959945679,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/residue","display_name":"Residue (chemistry)","score":0.6443909406661987},{"id":"https://openalex.org/keywords/hydrogen-bond","display_name":"Hydrogen bond","score":0.6082284450531006},{"id":"https://openalex.org/keywords/protein\u2013protein-interaction","display_name":"Protein\u2013protein interaction","score":0.5386824607849121},{"id":"https://openalex.org/keywords/ionic-bonding","display_name":"Ionic bonding","score":0.5078349709510803},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.4677489101886749},{"id":"https://openalex.org/keywords/hydrophobic-effect","display_name":"Hydrophobic effect","score":0.4286089241504669},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4041394889354706},{"id":"https://openalex.org/keywords/crystallography","display_name":"Crystallography","score":0.3944016396999359},{"id":"https://openalex.org/keywords/chemical-physics","display_name":"Chemical physics","score":0.36167800426483154},{"id":"https://openalex.org/keywords/molecule","display_name":"Molecule","score":0.30904102325439453},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.22838497161865234},{"id":"https://openalex.org/keywords/ion","display_name":"Ion","score":0.1528846025466919},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.14880743622779846},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.09378531575202942}],"concepts":[{"id":"https://openalex.org/C2781338088","wikidata":"https://www.wikidata.org/wiki/Q903495","display_name":"Residue (chemistry)","level":2,"score":0.6443909406661987},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.6082284450531006},{"id":"https://openalex.org/C11804247","wikidata":"https://www.wikidata.org/wiki/Q896177","display_name":"Protein\u2013protein interaction","level":2,"score":0.5386824607849121},{"id":"https://openalex.org/C2182769","wikidata":"https://www.wikidata.org/wiki/Q62500","display_name":"Ionic bonding","level":3,"score":0.5078349709510803},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.4677489101886749},{"id":"https://openalex.org/C90260826","wikidata":"https://www.wikidata.org/wiki/Q899157","display_name":"Hydrophobic effect","level":2,"score":0.4286089241504669},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4041394889354706},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3944016396999359},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.36167800426483154},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.30904102325439453},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.22838497161865234},{"id":"https://openalex.org/C145148216","wikidata":"https://www.wikidata.org/wiki/Q36496","display_name":"Ion","level":2,"score":0.1528846025466919},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14880743622779846},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.09378531575202942}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/nar/gkm423","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkm423","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_2/W473/9587798/gkm423.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:17584791","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17584791","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:eprints.iisc.ac.in:15627","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4377196309","display_name":"NOT FOUND REPOSITORY (Indian Institute of Science Bangalore)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I59270414","host_organization_name":"Indian Institute of Science Bangalore","host_organization_lineage":["https://openalex.org/I59270414"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1933215","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1933215","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkm423","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkm423","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_2/W473/9587798/gkm423.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320286","display_name":"University College London","ror":"https://ror.org/02jx3x895"},{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2110869427.pdf","grobid_xml":"https://content.openalex.org/works/W2110869427.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1604980477","https://openalex.org/W1792865908","https://openalex.org/W1926568554","https://openalex.org/W1972854116","https://openalex.org/W1980022131","https://openalex.org/W1982633968","https://openalex.org/W1991679405","https://openalex.org/W1994983243","https://openalex.org/W2007451197","https://openalex.org/W2011402521","https://openalex.org/W2026258231","https://openalex.org/W2045197143","https://openalex.org/W2049521571","https://openalex.org/W2050801417","https://openalex.org/W2051210276","https://openalex.org/W2058017150","https://openalex.org/W2060220522","https://openalex.org/W2065283382","https://openalex.org/W2065385636","https://openalex.org/W2070693796","https://openalex.org/W2071701532","https://openalex.org/W2094186244","https://openalex.org/W2098703706","https://openalex.org/W2117923629","https://openalex.org/W2118056979","https://openalex.org/W2118726693","https://openalex.org/W2119392004","https://openalex.org/W2136525667","https://openalex.org/W2140524371","https://openalex.org/W2140539543","https://openalex.org/W2142209403","https://openalex.org/W2151319417","https://openalex.org/W2154182570","https://openalex.org/W2167071905","https://openalex.org/W2170054546"],"related_works":["https://openalex.org/W2032398765","https://openalex.org/W2034187936","https://openalex.org/W3126804609","https://openalex.org/W2914490533","https://openalex.org/W4388442366","https://openalex.org/W2021213676","https://openalex.org/W1832993298","https://openalex.org/W1970785155","https://openalex.org/W1532803430","https://openalex.org/W4388831384"],"abstract_inverted_index":{"Interactions":[0,46,97],"within":[1,88],"a":[2,39,50,61,89,95,116,135,152],"protein":[3,40,62,90],"structure":[4,41,59],"and":[5,21,25,32,85,118,145],"interactions":[6,34,68,73,84,87,109,172],"between":[7,74,92,110,179],"proteins":[8,24,93],"in":[9,15,94,134],"an":[10,43,64],"assembly":[11],"are":[12,29,98,177],"essential":[13],"considerations":[14],"understanding":[16],"molecular":[17],"basis":[18,102],"of":[19,23,57,60,103,130,151,157,166],"stability":[20,37],"functions":[22],"their":[26],"complexes.":[27],"There":[28],"several":[30],"weak":[31],"strong":[33],"that":[35,176],"render":[36],"to":[38],"or":[42,63,91,173,181,184,188],"assembly.":[44],"Protein":[45],"Calculator":[47],"(PIC)":[48],"is":[49,126,148],"server":[51,125],"which,":[52],"given":[53],"the":[54,101,127,141,149,155,158,186],"coordinate":[55],"set":[56],"3D":[58],"assembly,":[65],"computes":[66],"various":[67],"such":[69,168],"as":[70,169],"disulphide":[71],"bonds,":[72,80],"hydrophobic":[75],"residues,":[76],"ionic":[77,174],"interactions,":[78,82,167,175],"hydrogen":[79],"aromatic-aromatic":[81],"aromatic-sulphur":[83],"cation-pi":[86],"complex.":[96],"calculated":[99],"on":[100],"standard,":[104],"published":[105],"criteria.":[106],"The":[107,121],"identified":[108],"residues":[111,183],"can":[112,161],"be":[113],"visualized":[114],"using":[115],"RasMol":[117],"Jmol":[119],"interface.":[120],"advantage":[122],"with":[123],"PIC":[124],"easy":[128],"availability":[129],"inter-residue":[131],"interaction":[132],"calculations":[133],"single":[136],"site.":[137],"It":[138],"also":[139,162],"determines":[140],"accessible":[142],"surface":[143,156,187],"area":[144],"residue-depth,":[146],"which":[147],"distance":[150],"residue":[153,171],"from":[154],"protein.":[159],"User":[160],"recognize":[163],"specific":[164],"kind":[165],"apolar-apolar":[170],"formed":[178],"buried":[180],"exposed":[182],"near":[185],"deep":[189],"inside.":[190]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":23},{"year":2024,"cited_by_count":33},{"year":2023,"cited_by_count":46},{"year":2022,"cited_by_count":63},{"year":2021,"cited_by_count":72},{"year":2020,"cited_by_count":74},{"year":2019,"cited_by_count":72},{"year":2018,"cited_by_count":46},{"year":2017,"cited_by_count":74},{"year":2016,"cited_by_count":84},{"year":2015,"cited_by_count":68},{"year":2014,"cited_by_count":63},{"year":2013,"cited_by_count":57},{"year":2012,"cited_by_count":37}],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2025-10-10T00:00:00"}