{"id":"https://openalex.org/W2096864392","doi":"https://doi.org/10.1093/nar/gkl999","title":"BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities","display_name":"BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities","publication_year":2006,"publication_date":"2006-12-03","ids":{"openalex":"https://openalex.org/W2096864392","doi":"https://doi.org/10.1093/nar/gkl999","mag":"2096864392","pmid":"https://pubmed.ncbi.nlm.nih.gov/17145705"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkl999","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkl999","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_1/D198/3895041/gkl999.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/35/suppl_1/D198/3895041/gkl999.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053763641","display_name":"Tianbo Liu","orcid":"https://orcid.org/0000-0002-8181-1790"},"institutions":[{"id":"https://openalex.org/I1312106833","display_name":"Biotechnology Institute","ror":"https://ror.org/00s1jty20","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1312106833"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"T. Liu","raw_affiliation_strings":["Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA","Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600, Gudelsky Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I1312106833"]},{"raw_affiliation_string":"Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600, Gudelsky Drive, Rockville, MD 20850, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101806120","display_name":"Yu\u2010Ting Lin","orcid":"https://orcid.org/0000-0003-0118-3315"},"institutions":[{"id":"https://openalex.org/I1312106833","display_name":"Biotechnology Institute","ror":"https://ror.org/00s1jty20","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1312106833"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y. Lin","raw_affiliation_strings":["Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute9600 Gudelsky Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute9600 Gudelsky Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I1312106833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113750019","display_name":"X. Wen","orcid":null},"institutions":[{"id":"https://openalex.org/I1312106833","display_name":"Biotechnology Institute","ror":"https://ror.org/00s1jty20","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1312106833"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"X. Wen","raw_affiliation_strings":["Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute9600 Gudelsky Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute9600 Gudelsky Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I1312106833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022355349","display_name":"Robert N. Jorissen","orcid":"https://orcid.org/0000-0001-9634-2803"},"institutions":[{"id":"https://openalex.org/I1312106833","display_name":"Biotechnology Institute","ror":"https://ror.org/00s1jty20","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1312106833"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. N. Jorissen","raw_affiliation_strings":["Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute9600 Gudelsky Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute9600 Gudelsky Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I1312106833"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049982297","display_name":"Michael K. Gilson","orcid":"https://orcid.org/0000-0002-3375-1738"},"institutions":[{"id":"https://openalex.org/I1312106833","display_name":"Biotechnology Institute","ror":"https://ror.org/00s1jty20","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1312106833"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. K. Gilson","raw_affiliation_strings":["Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA","Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute9600 Gudelsky Drive, Rockville, MD 20850, USA"],"affiliations":[{"raw_affiliation_string":"Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I1312106833"]},{"raw_affiliation_string":"Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute9600 Gudelsky Drive, Rockville, MD 20850, USA","institution_ids":["https://openalex.org/I1312106833"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5053763641"],"corresponding_institution_ids":["https://openalex.org/I1312106833"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":32.6857,"has_fulltext":true,"cited_by_count":2106,"citation_normalized_percentile":{"value":0.99853633,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"35","issue":"Database","first_page":"D198","last_page":"D201"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9835000038146973,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-data-bank","display_name":"Protein Data Bank (RCSB PDB)","score":0.7948182821273804},{"id":"https://openalex.org/keywords/protein-data-bank","display_name":"Protein Data Bank","score":0.7201868891716003},{"id":"https://openalex.org/keywords/affinities","display_name":"Affinities","score":0.6347352862358093},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6158723831176758},{"id":"https://openalex.org/keywords/protein-ligand","display_name":"Protein ligand","score":0.5451561212539673},{"id":"https://openalex.org/keywords/chemical-database","display_name":"Chemical database","score":0.5171727538108826},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5149756073951721},{"id":"https://openalex.org/keywords/virtual-screening","display_name":"Virtual screening","score":0.5083543658256531},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.4561253786087036},{"id":"https://openalex.org/keywords/upload","display_name":"Upload","score":0.44402721524238586},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.42850804328918457},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.3718689978122711},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.35026511549949646},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.3497042953968048},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.23488035798072815},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.1414678990840912},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.13991820812225342}],"concepts":[{"id":"https://openalex.org/C65556437","wikidata":"https://www.wikidata.org/wiki/Q766195","display_name":"Protein Data Bank (RCSB PDB)","level":2,"score":0.7948182821273804},{"id":"https://openalex.org/C119145174","wikidata":"https://www.wikidata.org/wiki/Q7251429","display_name":"Protein Data Bank","level":3,"score":0.7201868891716003},{"id":"https://openalex.org/C2780283098","wikidata":"https://www.wikidata.org/wiki/Q4688960","display_name":"Affinities","level":2,"score":0.6347352862358093},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6158723831176758},{"id":"https://openalex.org/C109095088","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Protein ligand","level":2,"score":0.5451561212539673},{"id":"https://openalex.org/C203394866","wikidata":"https://www.wikidata.org/wiki/Q2881060","display_name":"Chemical database","level":2,"score":0.5171727538108826},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5149756073951721},{"id":"https://openalex.org/C103697762","wikidata":"https://www.wikidata.org/wiki/Q4112105","display_name":"Virtual screening","level":3,"score":0.5083543658256531},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.4561253786087036},{"id":"https://openalex.org/C71901391","wikidata":"https://www.wikidata.org/wiki/Q7126699","display_name":"Upload","level":2,"score":0.44402721524238586},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.42850804328918457},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.3718689978122711},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.35026511549949646},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.3497042953968048},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.23488035798072815},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.1414678990840912},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13991820812225342}],"mesh":[{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1093/nar/gkl999","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkl999","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_1/D198/3895041/gkl999.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:17145705","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17145705","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:jupiter.its.unimelb.edu.au:11343/257301","is_oa":true,"landing_page_url":"http://hdl.handle.net/11343/257301","pdf_url":"http://hdl.handle.net/11343/257301","source":{"id":"https://openalex.org/S4377196259","display_name":"Minerva Access (University of Melbourne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I165779595","host_organization_name":"The University of Melbourne","host_organization_lineage":["https://openalex.org/I165779595"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2284865","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1751547","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1751547","is_oa":true,"landing_page_url":"http://doi.org/10.1093/nar/gkl999","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkl999","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkl999","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_1/D198/3895041/gkl999.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3332647531","display_name":"A Public Molecular Recognition Database","funder_award_id":"9808318","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332178","display_name":"National Institute of Standards and Technology","ror":"https://ror.org/05xpvk416"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2096864392.pdf","grobid_xml":"https://content.openalex.org/works/W2096864392.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1966041739","https://openalex.org/W1975147762","https://openalex.org/W1981065283","https://openalex.org/W1993046136","https://openalex.org/W1998643444","https://openalex.org/W2010519792","https://openalex.org/W2038702914","https://openalex.org/W2055043387","https://openalex.org/W2073110681","https://openalex.org/W2074872734","https://openalex.org/W2089035939","https://openalex.org/W2090631504","https://openalex.org/W2092285329","https://openalex.org/W2094125466","https://openalex.org/W2096729078","https://openalex.org/W2096864392","https://openalex.org/W2111078532","https://openalex.org/W2130479394","https://openalex.org/W2146465875","https://openalex.org/W2153635508","https://openalex.org/W2155063687","https://openalex.org/W2176516200","https://openalex.org/W2177508090","https://openalex.org/W2615576800","https://openalex.org/W2952136673","https://openalex.org/W3120421331","https://openalex.org/W4236236547","https://openalex.org/W4251828057"],"related_works":["https://openalex.org/W2020669016","https://openalex.org/W2114363966","https://openalex.org/W4387033830","https://openalex.org/W3013529667","https://openalex.org/W1559108998","https://openalex.org/W2139779008","https://openalex.org/W1993046136","https://openalex.org/W2006718226","https://openalex.org/W2053132779","https://openalex.org/W2019285562"],"abstract_inverted_index":{"BindingDB":[0,65,96,129],"(http://www.bindingdb.org)":[1],"is":[2],"a":[3,68,119],"publicly":[4],"accessible":[5],"database":[6,121],"currently":[7],"containing":[8],"approximately":[9,28],"20,000":[10],"experimentally":[11],"determined":[12],"binding":[13],"affinities":[14],"of":[15,70,104,118],"protein-ligand":[16],"complexes,":[17],"for":[18,53,107,115],"110":[19],"protein":[20,81,85],"targets":[21],"including":[22,73],"isoforms":[23],"and":[24,27,52,79,84,89,142,144,147],"mutational":[25],"variants,":[26],"11,000":[29],"small":[30],"molecule":[31],"ligands.":[32],"The":[33,64,126],"data":[34,41,56,127,135],"are":[35,47,57,130],"extracted":[36],"from":[37],"the":[38,60,102,113,124,137,149],"scientific":[39],"literature,":[40],"collection":[42],"focusing":[43],"on":[44],"proteins":[45],"that":[46],"drug-targets":[48,51],"or":[49,110],"candidate":[50],"which":[54],"structural":[55,134],"present":[58],"in":[59,101,128,136,151],"Protein":[61],"Data":[62,92],"Bank.":[63],"website":[66],"supports":[67],"range":[69],"query":[71],"types,":[72],"searches":[74],"by":[75,95,123],"chemical":[76,143],"structure,":[77],"substructure":[78],"similarity;":[80],"sequence;":[82],"ligand":[83],"names;":[86],"affinity":[87],"ranges":[88],"molecular":[90],"weight.":[91],"sets":[93],"generated":[94],"queries":[97],"can":[98],"be":[99],"downloaded":[100],"form":[103],"annotated":[105],"SDfiles":[106],"further":[108],"analysis,":[109],"used":[111],"as":[112],"basis":[114],"virtual":[116],"screening":[117],"compound":[120],"uploaded":[122],"user.":[125],"linked":[131],"both":[132],"to":[133,148],"PDB":[138,140],"via":[139,153],"IDs":[141],"sequence":[145],"searches,":[146],"literature":[150],"PubMed":[152,154],"IDs.":[155]},"counts_by_year":[{"year":2026,"cited_by_count":53},{"year":2025,"cited_by_count":274},{"year":2024,"cited_by_count":209},{"year":2023,"cited_by_count":175},{"year":2022,"cited_by_count":157},{"year":2021,"cited_by_count":131},{"year":2020,"cited_by_count":111},{"year":2019,"cited_by_count":102},{"year":2018,"cited_by_count":75},{"year":2017,"cited_by_count":83},{"year":2016,"cited_by_count":88},{"year":2015,"cited_by_count":119},{"year":2014,"cited_by_count":98},{"year":2013,"cited_by_count":93},{"year":2012,"cited_by_count":91}],"updated_date":"2026-04-04T08:04:53.788161","created_date":"2025-10-10T00:00:00"}