{"id":"https://openalex.org/W2144363281","doi":"https://doi.org/10.1093/nar/gkl910","title":"The SUPERFAMILY database in 2007: families and functions","display_name":"The SUPERFAMILY database in 2007: families and functions","publication_year":2006,"publication_date":"2006-11-13","ids":{"openalex":"https://openalex.org/W2144363281","doi":"https://doi.org/10.1093/nar/gkl910","mag":"2144363281","pmid":"https://pubmed.ncbi.nlm.nih.gov/17098927"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkl910","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkl910","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_1/D308/3868498/gkl910.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/35/suppl_1/D308/3868498/gkl910.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067726490","display_name":"Derek A. Wilson","orcid":null},"institutions":[{"id":"https://openalex.org/I170203145","display_name":"MRC Laboratory of Molecular Biology","ror":"https://ror.org/00tw3jy02","country_code":"GB","type":"facility","lineage":["https://openalex.org/I170203145","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"D. Wilson","raw_affiliation_strings":["MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. superfamily@mrc-lmb.cam.ac.uk","MRC, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK"],"affiliations":[{"raw_affiliation_string":"MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. superfamily@mrc-lmb.cam.ac.uk","institution_ids":["https://openalex.org/I170203145"]},{"raw_affiliation_string":"MRC, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK","institution_ids":["https://openalex.org/I170203145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083352651","display_name":"Mary Madera","orcid":"https://orcid.org/0000-0003-4687-8591"},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Madera","raw_affiliation_strings":["1Biomolecular Engineering, University of California Santa CruzSanta Cruz, CA 95064, USA"],"affiliations":[{"raw_affiliation_string":"1Biomolecular Engineering, University of California Santa CruzSanta Cruz, CA 95064, USA","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035122021","display_name":"Christine Vogel","orcid":"https://orcid.org/0000-0002-2856-3118"},"institutions":[{"id":"https://openalex.org/I86519309","display_name":"The University of Texas at Austin","ror":"https://ror.org/00hj54h04","country_code":"US","type":"education","lineage":["https://openalex.org/I86519309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Vogel","raw_affiliation_strings":["2Institute for Cellular and Molecular Biology, University of Texas at AustinAustin, TX, USA"],"affiliations":[{"raw_affiliation_string":"2Institute for Cellular and Molecular Biology, University of Texas at AustinAustin, TX, USA","institution_ids":["https://openalex.org/I86519309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110253216","display_name":"C. Chothia","orcid":null},"institutions":[{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C. Chothia","raw_affiliation_strings":["Medical Research Council"],"affiliations":[{"raw_affiliation_string":"Medical Research Council","institution_ids":["https://openalex.org/I90344618"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001806472","display_name":"J. Gough","orcid":null},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"funder","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J. Gough","raw_affiliation_strings":["3Unite de Bioinformatique Structurale, Institute Pasteur 25-28 Rue du Docteur Roux75724 Paris Cedex, Paris, France"],"affiliations":[{"raw_affiliation_string":"3Unite de Bioinformatique Structurale, Institute Pasteur 25-28 Rue du Docteur Roux75724 Paris Cedex, Paris, France","institution_ids":["https://openalex.org/I157536573"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5067726490"],"corresponding_institution_ids":["https://openalex.org/I170203145"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":10.0802,"has_fulltext":false,"cited_by_count":253,"citation_normalized_percentile":{"value":0.98936742,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"35","issue":"Database","first_page":"D308","last_page":"D313"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9869999885559082,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9869999885559082,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9817000031471252,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9629999995231628,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.9474973678588867},{"id":"https://openalex.org/keywords/superfamily","display_name":"SUPERFAMILY","score":0.6675281524658203},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.40567290782928467},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.39295998215675354},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.3824099004268646},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1401658058166504}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9474973678588867},{"id":"https://openalex.org/C92028520","wikidata":"https://www.wikidata.org/wiki/Q7395025","display_name":"SUPERFAMILY","level":3,"score":0.6675281524658203},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.40567290782928467},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39295998215675354},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.3824099004268646},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1401658058166504},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":10,"locations":[{"id":"doi:10.1093/nar/gkl910","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkl910","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_1/D308/3868498/gkl910.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:17098927","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17098927","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/022a3be9-b903-42e1-b5c2-c3ba271a4d4c","is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/022a3be9-b903-42e1-b5c2-c3ba271a4d4c","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wilson, D, Madera, M, Vogel, C, Chothia, C & Gough, J 2007, 'The SUPERFAMILY database in 2007: families and functions', Nucleic Acids Research, vol. 35, 308-313. < http://www.cs.bris.ac.uk/Publications/pub_master.jsp?id=1040000 >","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.102.937","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.102.937","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://nar.oxfordjournals.org/cgi/screenpdf/35/suppl_1/D308.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.126.6085","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.126.6085","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://nar.oxfordjournals.org/cgi/reprint/gkl910v1.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.594.2911","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.594.2911","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://supfam.cs.bris.ac.uk/SUPERFAMILY/articles/nar2007.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.622.8632","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.622.8632","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://nar.oxfordjournals.org/content/early/2006/11/10/nar.gkl910.full.pdf","raw_type":"text"},{"id":"pmh:oai:europepmc.org:2284762","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1669749","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1669749","is_oa":true,"landing_page_url":"http://doi.org/10.1093/nar/gkl910","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmh:oai:research-information.bris.ac.uk:publications/022a3be9-b903-42e1-b5c2-c3ba271a4d4c","is_oa":false,"landing_page_url":"http://www.cs.bris.ac.uk/Publications/pub_master.jsp?id=1040000","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wilson, D, Madera, M, Vogel, C, Chothia, C & Gough, J 2007, 'The SUPERFAMILY database in 2007: families and functions', Nucleic Acids Research, vol. 35, 308-313. < http://www.cs.bris.ac.uk/Publications/pub_master.jsp?id=1040000 >","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1093/nar/gkl910","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkl910","pdf_url":"https://academic.oup.com/nar/article-pdf/35/suppl_1/D308/3868498/gkl910.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320868","display_name":"Boehringer Ingelheim Fonds","ror":"https://ror.org/00dkye506"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2144363281.pdf","grobid_xml":"https://content.openalex.org/works/W2144363281.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1995404781","https://openalex.org/W2001914359","https://openalex.org/W2050908913","https://openalex.org/W2076502650","https://openalex.org/W2099946731","https://openalex.org/W2103017472","https://openalex.org/W2119195082","https://openalex.org/W2125725297","https://openalex.org/W2131889225","https://openalex.org/W2136280642","https://openalex.org/W2140244239","https://openalex.org/W2148829626","https://openalex.org/W2148950394","https://openalex.org/W2149138213","https://openalex.org/W2151831732","https://openalex.org/W2155606054","https://openalex.org/W2158714788","https://openalex.org/W2161732286","https://openalex.org/W2162270048","https://openalex.org/W2164886928","https://openalex.org/W2166458835","https://openalex.org/W2170173760","https://openalex.org/W4210580032"],"related_works":["https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W1971568933","https://openalex.org/W2013243191","https://openalex.org/W2117258802"],"abstract_inverted_index":{"The":[0,71,142],"SUPERFAMILY":[1,43,123,143],"database":[2,124,144],"provides":[3],"protein":[4,15,85,150],"domain":[5,44,78,88,90],"assignments,":[6,86],"at":[7],"the":[8,13,122],"SCOP":[9],"'superfamily'":[10],"level,":[11],"for":[12,65,83,100,148],"predicted":[14],"sequences":[16,113],"in":[17],"over":[18],"400":[19],"completed":[20],"genomes.":[21],"A":[22],"superfamily":[23],"groups":[24],"together":[25],"domains":[26],"of":[27,53,95,110,132],"different":[28],"families":[29],"which":[30],"have":[31],"a":[32,101,138],"common":[33],"evolutionary":[34],"ancestor":[35],"based":[36],"on":[37],"structural,":[38],"functional":[39,140],"and":[40,60,67,80,114,125,136,152,157,162],"sequence":[41],"data.":[42],"assignments":[45,62,135],"are":[46,63],"generated":[47],"using":[48],"an":[49],"expert":[50],"curated":[51],"set":[52],"profile":[54],"hidden":[55],"Markov":[56],"models.":[57],"All":[58],"models":[59],"structural":[61,158],"available":[64],"browsing":[66],"download":[68],"from":[69],"http://supfam.org.":[70],"web":[72],"interface":[73],"includes":[74],"services":[75],"such":[76],"as":[77],"architectures":[79],"alignment":[81],"details":[82],"all":[84],"searchable":[87],"combinations,":[89],"occurrence":[91],"network":[92],"visualization,":[93],"detection":[94],"over-":[96],"or":[97],"under-represented":[98],"superfamilies":[99],"given":[102],"genome":[103],"by":[104],"comparison":[105],"with":[106],"other":[107],"genomes,":[108],"assignment":[109],"manually":[111],"submitted":[112],"keyword":[115],"searches.":[116],"In":[117],"this":[118],"update":[119],"we":[120],"describe":[121],"outline":[126],"two":[127],"major":[128],"developments:":[129],"(i)":[130],"incorporation":[131],"family":[133],"level":[134],"(ii)":[137],"superfamily-level":[139],"annotation.":[141],"can":[145],"be":[146],"used":[147],"general":[149],"evolution":[151],"superfamily-specific":[153],"studies,":[154],"genomic":[155],"annotation,":[156],"genomics":[159],"target":[160],"suggestion":[161],"assessment.":[163]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":21}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}