{"id":"https://openalex.org/W1991618042","doi":"https://doi.org/10.1093/nar/gkj060","title":"ICDS database: interrupted CoDing sequences in prokaryotic genomes","display_name":"ICDS database: interrupted CoDing sequences in prokaryotic genomes","publication_year":2005,"publication_date":"2005-12-28","ids":{"openalex":"https://openalex.org/W1991618042","doi":"https://doi.org/10.1093/nar/gkj060","mag":"1991618042","pmid":"https://pubmed.ncbi.nlm.nih.gov/16381882"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkj060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkj060","pdf_url":"https://academic.oup.com/nar/article-pdf/34/suppl_1/D338/3924602/gkj060.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/34/suppl_1/D338/3924602/gkj060.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034099147","display_name":"Emmanuel Perrodou","orcid":null},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"E. Perrodou","raw_affiliation_strings":["Laboratoire de Biologie et G\u00e9nomique Structurales, Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP BP 163, 67404 Illkirch Cedex, France","Laboratoire de Biologie et G\u00e9nomique Structurales, Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP  BP 163, 67404 Illkirch cedex, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie et G\u00e9nomique Structurales, Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP BP 163, 67404 Illkirch Cedex, France","institution_ids":[]},{"raw_affiliation_string":"Laboratoire de Biologie et G\u00e9nomique Structurales, Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire, CNRS/INSERM/ULP  BP 163, 67404 Illkirch cedex, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I1294671590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5034099147"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":1.2658,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.77235961,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"34","issue":"90001","first_page":"D338","last_page":"D343"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8284820914268494},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.6718396544456482},{"id":"https://openalex.org/keywords/whole-genome-sequencing","display_name":"Whole genome sequencing","score":0.5841588377952576},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.577072262763977},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.49472638964653015},{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.4522169828414917},{"id":"https://openalex.org/keywords/sequence-analysis","display_name":"Sequence analysis","score":0.4328334629535675},{"id":"https://openalex.org/keywords/sequence-database","display_name":"Sequence database","score":0.4254688620567322},{"id":"https://openalex.org/keywords/personal-genomics","display_name":"Personal genomics","score":0.419128954410553},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3519662022590637},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.33949095010757446}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8284820914268494},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6718396544456482},{"id":"https://openalex.org/C24432333","wikidata":"https://www.wikidata.org/wiki/Q2068526","display_name":"Whole genome sequencing","level":4,"score":0.5841588377952576},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.577072262763977},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.49472638964653015},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.4522169828414917},{"id":"https://openalex.org/C61053724","wikidata":"https://www.wikidata.org/wiki/Q1154615","display_name":"Sequence analysis","level":3,"score":0.4328334629535675},{"id":"https://openalex.org/C41584329","wikidata":"https://www.wikidata.org/wiki/Q175902","display_name":"Sequence database","level":3,"score":0.4254688620567322},{"id":"https://openalex.org/C24103923","wikidata":"https://www.wikidata.org/wiki/Q7170583","display_name":"Personal genomics","level":5,"score":0.419128954410553},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3519662022590637},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33949095010757446}],"mesh":[{"descriptor_ui":"D001407","descriptor_name":"Bacillus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001407","descriptor_name":"Bacillus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001407","descriptor_name":"Bacillus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016368","descriptor_name":"Frameshift Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016368","descriptor_name":"Frameshift Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016368","descriptor_name":"Frameshift Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018388","descriptor_name":"Codon, Terminator","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018388","descriptor_name":"Codon, Terminator","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018388","descriptor_name":"Codon, Terminator","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020102","descriptor_name":"Mycobacterium smegmatis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020102","descriptor_name":"Mycobacterium smegmatis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020102","descriptor_name":"Mycobacterium smegmatis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020745","descriptor_name":"Genome, Archaeal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020745","descriptor_name":"Genome, Archaeal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020745","descriptor_name":"Genome, Archaeal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1093/nar/gkj060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkj060","pdf_url":"https://academic.oup.com/nar/article-pdf/34/suppl_1/D338/3924602/gkj060.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:16381882","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16381882","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:HAL:hal-00188107v1","is_oa":false,"landing_page_url":"https://hal.science/hal-00188107","pdf_url":null,"source":{"id":"https://openalex.org/S4406922466","display_name":"SPIRE - Sciences Po Institutional REpository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Research, 2006, 34 (Database issue), pp.D338-43. ⟨10.1093/nar/gkj060⟩","raw_type":"Journal articles"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10034631","is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/10034631/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"   Nucleic Acids Res , 34  (Database)   D338-D343.   (2006)      ","raw_type":"Article"},{"id":"pmh:oai:europepmc.org:156879","is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1347423","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1347423","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1347423","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkj060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkj060","pdf_url":"https://academic.oup.com/nar/article-pdf/34/suppl_1/D338/3924602/gkj060.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","score":0.41999998688697815,"display_name":"Life in Land"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1991618042.pdf","grobid_xml":"https://content.openalex.org/works/W1991618042.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1574779369","https://openalex.org/W1921542770","https://openalex.org/W1977415113","https://openalex.org/W1983538916","https://openalex.org/W1989274210","https://openalex.org/W1991303432","https://openalex.org/W1995511427","https://openalex.org/W2045538822","https://openalex.org/W2051543845","https://openalex.org/W2053009004","https://openalex.org/W2053427917","https://openalex.org/W2056145855","https://openalex.org/W2086199046","https://openalex.org/W2088931841","https://openalex.org/W2106073189","https://openalex.org/W2113230913","https://openalex.org/W2114142760","https://openalex.org/W2133111678","https://openalex.org/W2133253129","https://openalex.org/W2150818385","https://openalex.org/W2153463868","https://openalex.org/W2154478075","https://openalex.org/W2155172429","https://openalex.org/W2158344758","https://openalex.org/W2158714788","https://openalex.org/W2161229339","https://openalex.org/W2164217177","https://openalex.org/W3164064520","https://openalex.org/W4239460348","https://openalex.org/W4285719527","https://openalex.org/W4294239959"],"related_works":["https://openalex.org/W2912862995","https://openalex.org/W3129816939","https://openalex.org/W2101501829","https://openalex.org/W2985427592","https://openalex.org/W2003194288","https://openalex.org/W2060263731","https://openalex.org/W391093122","https://openalex.org/W2581600691","https://openalex.org/W2183615490","https://openalex.org/W2028473472"],"abstract_inverted_index":{"Unrecognized":[0],"frameshifts,":[1,132],"in-frame":[2],"stop":[3],"codons":[4],"and":[5,138,155,177,180,186],"sequencing":[6],"errors":[7],"lead":[8],"to":[9,28,87,173],"Interrupted":[10,36],"CoDing":[11,37],"Sequence":[12,38],"(ICDS)":[13],"that":[14],"can":[15,53],"seriously":[16],"affect":[17],"all":[18],"subsequent":[19],"steps":[20],"of":[21,69,92,129,135,144,149,158,162,167,183,189],"functional":[22],"characterization,":[23],"from":[24,110,141],"in":[25,47],"silico":[26],"analysis":[27],"high-throughput":[29],"proteomic":[30],"projects.":[31],"Here,":[32],"we":[33,94],"describe":[34],"the":[35,78,83,89,142,145,163,175,187],"database":[39,102],"containing":[40],"ICDS":[41,52,79,124,137,161],"detected":[42],"by":[43,56,119],"a":[44,63,127],"similarity-based":[45],"approach":[46],"80":[48],"complete":[49],"prokaryotic":[50],"genomes.":[51,113],"be":[54,104],"retrieved":[55],"species":[57],"browsing":[58],"or":[59],"similarity":[60],"searches":[61],"via":[62],"web":[64],"interface":[65],"(http://www-bio3d-igbmc.u-strasbg.fr/ICDS/).":[66],"The":[67,101],"definition":[68],"each":[70],"interrupted":[71],"gene":[72],"is":[73],"provided":[74],"as":[75,77],"well":[76],"genomic":[80,147],"localization":[81],"with":[82,107],"surrounding":[84],"sequence.":[85],"Furthermore,":[86],"facilitate":[88],"experimental":[90],"characterization":[91],"ICDS,":[93],"propose":[95],"optimized":[96],"primers":[97],"for":[98],"re-sequencing":[99,157],"purposes.":[100],"will":[103],"regularly":[105],"updated":[106],"additional":[108],"data":[109],"ongoing":[111],"sequenced":[112,165],"Our":[114],"strategy":[115],"has":[116],"been":[117],"validated":[118],"three":[120],"independent":[121],"tests:":[122],"(i)":[123],"prediction":[125],"on":[126],"benchmark":[128],"artificially":[130],"created":[131],"(ii)":[133],"comparison":[134,143],"predicted":[136,160],"results":[139],"obtained":[140],"two":[146],"sequences":[148],"Bacillus":[150],"licheniformis":[151],"strain":[152],"ATCC":[153],"14580":[154],"(iii)":[156],"25":[159],"recently":[164],"genome":[166],"Mycobacterium":[168],"smegmatis.":[169],"This":[170],"allows":[171],"us":[172],"estimate":[174],"specificity":[176],"sensitivity":[178],"(95":[179],"82%,":[181],"respectively)":[182],"our":[184],"program":[185],"efficiency":[188],"primer":[190],"determination.":[191]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}