{"id":"https://openalex.org/W2066285332","doi":"https://doi.org/10.1093/nar/gkg123","title":"MitoDrome: a database of Drosophila melanogaster nuclear genes encoding proteins targeted to the mitochondrion","display_name":"MitoDrome: a database of Drosophila melanogaster nuclear genes encoding proteins targeted to the mitochondrion","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2066285332","doi":"https://doi.org/10.1093/nar/gkg123","mag":"2066285332","pmid":"https://pubmed.ncbi.nlm.nih.gov/12520013"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkg123","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkg123","pdf_url":"https://academic.oup.com/nar/article-pdf/31/1/322/7128321/gkg123.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/nar/article-pdf/31/1/322/7128321/gkg123.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081495214","display_name":"Marco Sardiello","orcid":"https://orcid.org/0000-0001-6484-0250"},"institutions":[{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"M. Sardiello","raw_affiliation_strings":["Dipartimento di Genetica e Anatomia Patologica, Universit\u00e0 di Bari, Via E. Orabona 4, 70126 Bari, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Genetica e Anatomia Patologica, Universit\u00e0 di Bari, Via E. Orabona 4, 70126 Bari, Italy","institution_ids":["https://openalex.org/I5561750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5081495214"],"corresponding_institution_ids":["https://openalex.org/I5561750"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":null,"fwci":1.2491,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.77885825,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"31","issue":"1","first_page":"322","last_page":"324"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.9552425742149353},{"id":"https://openalex.org/keywords/drosophila-melanogaster","display_name":"Drosophila melanogaster","score":0.8662782311439514},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.6958600282669067},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.6453041434288025},{"id":"https://openalex.org/keywords/mitochondrion","display_name":"Mitochondrion","score":0.5904139280319214},{"id":"https://openalex.org/keywords/nuclear-gene","display_name":"Nuclear gene","score":0.5466932654380798},{"id":"https://openalex.org/keywords/drosophilidae","display_name":"Drosophilidae","score":0.5160967707633972},{"id":"https://openalex.org/keywords/drosophila","display_name":"Drosophila (subgenus)","score":0.5116763114929199},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4503921866416931},{"id":"https://openalex.org/keywords/mitochondrial-dna","display_name":"Mitochondrial DNA","score":0.41214632987976074},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.33335018157958984}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9552425742149353},{"id":"https://openalex.org/C2780104201","wikidata":"https://www.wikidata.org/wiki/Q130888","display_name":"Drosophila melanogaster","level":3,"score":0.8662782311439514},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6958600282669067},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6453041434288025},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.5904139280319214},{"id":"https://openalex.org/C20750100","wikidata":"https://www.wikidata.org/wiki/Q7068120","display_name":"Nuclear gene","level":4,"score":0.5466932654380798},{"id":"https://openalex.org/C2777379243","wikidata":"https://www.wikidata.org/wiki/Q1054318","display_name":"Drosophilidae","level":4,"score":0.5160967707633972},{"id":"https://openalex.org/C2776041557","wikidata":"https://www.wikidata.org/wiki/Q3715451","display_name":"Drosophila (subgenus)","level":3,"score":0.5116763114929199},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4503921866416931},{"id":"https://openalex.org/C24586158","wikidata":"https://www.wikidata.org/wiki/Q27075","display_name":"Mitochondrial DNA","level":3,"score":0.41214632987976074},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33335018157958984}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017344","descriptor_name":"Genes, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017344","descriptor_name":"Genes, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017344","descriptor_name":"Genes, Insect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1093/nar/gkg123","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkg123","pdf_url":"https://academic.oup.com/nar/article-pdf/31/1/322/7128321/gkg123.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:12520013","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12520013","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.515.6038","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.515.6038","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://nar.oxfordjournals.org/content/31/1/322.full.pdf","raw_type":"text"},{"id":"pmh:oai:europepmc.org:158746","is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC165570","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:165570","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:165570","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/165570","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmh:oai:ricerca.uniba.it:11586/22042","is_oa":false,"landing_page_url":"http://hdl.handle.net/11586/22042","pdf_url":null,"source":{"id":"https://openalex.org/S4377196296","display_name":"CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I5561750","host_organization_name":"University of Bari Aldo Moro","host_organization_lineage":["https://openalex.org/I5561750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/nar/gkg123","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkg123","pdf_url":"https://academic.oup.com/nar/article-pdf/31/1/322/7128321/gkg123.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5400000214576721}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2066285332.pdf","grobid_xml":"https://content.openalex.org/works/W2066285332.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W107544894","https://openalex.org/W2034767282","https://openalex.org/W2044895959","https://openalex.org/W2157363882","https://openalex.org/W2166834940","https://openalex.org/W4251507866","https://openalex.org/W4252546523"],"related_works":["https://openalex.org/W424256774","https://openalex.org/W2478313773","https://openalex.org/W2143275805","https://openalex.org/W2806288029","https://openalex.org/W4241772103","https://openalex.org/W2332645570","https://openalex.org/W2173880","https://openalex.org/W2220458821","https://openalex.org/W4311607074","https://openalex.org/W4323037479"],"abstract_inverted_index":{"Mitochondria":[0],"are":[1,27,40,149,197],"organelles":[2],"present":[3],"in":[4,42,72,84,106,168,183,199],"the":[5,17,20,30,43,51,68,79,91,97,111,137,145,152,159,169,174,178,208],"cytoplasm":[6],"of":[7,19,50,70,81,90,114,124,136,154],"most":[8,138],"eukaryotic":[9],"cells;":[10],"although":[11],"they":[12,39],"have":[13],"their":[14],"own":[15],"DNA,":[16],"majority":[18],"proteins":[21,105,120,157],"necessary":[22],"for":[23,64,103,118,144],"a":[24,65,142,200],"functional":[25,112],"mitochondrion":[26,44,52],"coded":[28],"by":[29],"nuclear":[31,100,115],"DNA":[32],"and":[33,37,56,87,121,141,163,203],"only":[34],"after":[35],"transcription":[36],"translation":[38],"imported":[41],"as":[45],"proteins.":[46],"The":[47,189],"primary":[48],"role":[49,83],"is":[53,74,94,134,192],"electron":[54],"transport":[55],"oxidative":[57],"phosphorylation.":[58],"Although":[59],"it":[60],"has":[61],"been":[62],"studied":[63,139],"long":[66],"time,":[67],"interest":[69],"researchers":[71],"mitochondria":[73],"still":[75],"alive":[76],"thanks":[77],"to":[78,95,108,110,122,128,177],"discovery":[80],"mitochondrial":[82,104,119,129,156],"apoptosis,":[85],"aging":[86],"cancer.":[88],"Aim":[89],"MitoDrome":[92,175,190],"database":[93,191],"annotate":[96],"Drosophila":[98,160],"melanogaster":[99,133],"genes":[101,116],"coding":[102,117],"order":[107],"contribute":[109],"characterization":[113],"knowledge":[123],"gene":[125],"diseases":[126],"related":[127,179],"dysfunctions.":[130],"Indeed":[131],"D.":[132],"one":[135],"organisms":[140],"model":[143],"Human":[146,155],"genome.":[147],"Data":[148,196],"derived":[150],"from":[151,173],"comparison":[153],"versus":[158],"genome,":[161],"ESTs":[162],"cDNA":[164],"sequence":[165],"data":[166],"available":[167,182,193],"FlyBase":[170],"database.":[171],"Links":[172],"entries":[176,181],"homologous":[180],"MitoNuC":[184],"will":[185],"be":[186,205],"soon":[187],"imple-mented.":[188],"at":[194],"http://bighost.area.ba.cnr.it/BIG/MitoDrome.":[195],"organised":[198],"flat-file":[201],"format":[202],"can":[204],"retrieved":[206],"using":[207],"SRS":[209],"system.":[210]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-03-10T16:38:18.471706","created_date":"2025-10-10T00:00:00"}