{"id":"https://openalex.org/W4307972748","doi":"https://doi.org/10.1093/nar/gkac997","title":"<i>PGG</i>.MHC: toward understanding the diversity of major histocompatibility complexes in human populations","display_name":"<i>PGG</i>.MHC: toward understanding the diversity of major histocompatibility complexes in human populations","publication_year":2022,"publication_date":"2022-11-02","ids":{"openalex":"https://openalex.org/W4307972748","doi":"https://doi.org/10.1093/nar/gkac997","pmid":"https://pubmed.ncbi.nlm.nih.gov/36321663"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkac997","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac997","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1102/48441635/gkac997.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1102/48441635/gkac997.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114950196","display_name":"Xiaohan Zhao","orcid":"https://orcid.org/0000-0002-4556-8666"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":null,"type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaohan Zhao","raw_affiliation_strings":["Human Phenome Institute, Zhangjiang Fudan\u00a0International Innovation Center, and Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai 201203, China","State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China"],"affiliations":[{"raw_affiliation_string":"Human Phenome Institute, Zhangjiang Fudan\u00a0International Innovation Center, and Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai 201203, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085005422","display_name":"Sen Ma","orcid":"https://orcid.org/0000-0001-8183-096X"},"institutions":[{"id":"https://openalex.org/I4210096013","display_name":"Shanghai Institute of Nutrition and Health","ror":"https://ror.org/00rytkh49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210096013"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sen Ma","raw_affiliation_strings":["Key Laboratory of\u00a0Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of\u00a0Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China","institution_ids":["https://openalex.org/I4210096013","https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039296582","display_name":"Baonan Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":null,"type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baonan Wang","raw_affiliation_strings":["Human Phenome Institute, Zhangjiang Fudan\u00a0International Innovation Center, and Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai 201203, China","State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China"],"affiliations":[{"raw_affiliation_string":"Human Phenome Institute, Zhangjiang Fudan\u00a0International Innovation Center, and Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai 201203, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019945393","display_name":"Xuetong Jiang","orcid":"https://orcid.org/0000-0003-2562-9318"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":null,"type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuetong Jiang","raw_affiliation_strings":["State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}]},{"author_position":"middle","author":{"id":null,"display_name":"The\u00a0Han100K Initiative","orcid":null},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":null,"type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"The\u00a0Han100K Initiative","raw_affiliation_strings":["Department of Liver\u00a0Surgery and Transplantation Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China","State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China","Human Phenome Institute, Zhangjiang Fudan\u00a0International Innovation Center, and Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai 201203, China"],"affiliations":[{"raw_affiliation_string":"Department of Liver\u00a0Surgery and Transplantation Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]},{"raw_affiliation_string":"Human Phenome Institute, Zhangjiang Fudan\u00a0International Innovation Center, and Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai 201203, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"last","author":{"id":null,"display_name":"Shuhua Xu","orcid":"https://orcid.org/0000-0002-1975-1002"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":null,"type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuhua Xu","raw_affiliation_strings":["Department of Liver\u00a0Surgery and Transplantation Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China","Human Phenome Institute, Zhangjiang Fudan\u00a0International Innovation Center, and Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai 201203, China","State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China"],"affiliations":[{"raw_affiliation_string":"Department of Liver\u00a0Surgery and Transplantation Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Human Phenome Institute, Zhangjiang Fudan\u00a0International Innovation Center, and Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai 201203, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"State Key Laboratory\u00a0of Genetic Engineering, Center for Evolutionary Biology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074","https://openalex.org/I4391768242"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":0.8501,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.71138291,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"51","issue":"D1","first_page":"D1102","last_page":"D1108"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8146653771400452},{"id":"https://openalex.org/keywords/human-leukocyte-antigen","display_name":"Human leukocyte antigen","score":0.7708689570426941},{"id":"https://openalex.org/keywords/major-histocompatibility-complex","display_name":"Major histocompatibility complex","score":0.7641080021858215},{"id":"https://openalex.org/keywords/imputation","display_name":"Imputation (statistics)","score":0.6199048161506653},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5633148550987244},{"id":"https://openalex.org/keywords/exome","display_name":"Exome","score":0.5115340948104858},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.4784260392189026},{"id":"https://openalex.org/keywords/haplotype","display_name":"Haplotype","score":0.4779658019542694},{"id":"https://openalex.org/keywords/balancing-selection","display_name":"Balancing selection","score":0.4670874774456024},{"id":"https://openalex.org/keywords/mhc-class-i","display_name":"MHC class I","score":0.46534618735313416},{"id":"https://openalex.org/keywords/allele","display_name":"Allele","score":0.46303805708885193},{"id":"https://openalex.org/keywords/genotyping","display_name":"Genotyping","score":0.43568745255470276},{"id":"https://openalex.org/keywords/allele-frequency","display_name":"Allele frequency","score":0.423420786857605},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3648204505443573},{"id":"https://openalex.org/keywords/exome-sequencing","display_name":"Exome sequencing","score":0.27876710891723633},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.17554497718811035},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.17236343026161194},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1662059724330902},{"id":"https://openalex.org/keywords/antigen","display_name":"Antigen","score":0.13408896327018738},{"id":"https://openalex.org/keywords/missing-data","display_name":"Missing data","score":0.08617162704467773},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.06041783094406128}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8146653771400452},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.7708689570426941},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.7641080021858215},{"id":"https://openalex.org/C58041806","wikidata":"https://www.wikidata.org/wiki/Q1660484","display_name":"Imputation (statistics)","level":3,"score":0.6199048161506653},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5633148550987244},{"id":"https://openalex.org/C10590036","wikidata":"https://www.wikidata.org/wiki/Q417664","display_name":"Exome","level":5,"score":0.5115340948104858},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4784260392189026},{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.4779658019542694},{"id":"https://openalex.org/C137848329","wikidata":"https://www.wikidata.org/wiki/Q804635","display_name":"Balancing selection","level":4,"score":0.4670874774456024},{"id":"https://openalex.org/C170627219","wikidata":"https://www.wikidata.org/wiki/Q13218497","display_name":"MHC class I","level":4,"score":0.46534618735313416},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.46303805708885193},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.43568745255470276},{"id":"https://openalex.org/C37463918","wikidata":"https://www.wikidata.org/wiki/Q387981","display_name":"Allele frequency","level":4,"score":0.423420786857605},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3648204505443573},{"id":"https://openalex.org/C16671776","wikidata":"https://www.wikidata.org/wiki/Q5420592","display_name":"Exome sequencing","level":4,"score":0.27876710891723633},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.17554497718811035},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.17236343026161194},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1662059724330902},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.13408896327018738},{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.08617162704467773},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.06041783094406128},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006239","descriptor_name":"Haplotypes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006239","descriptor_name":"Haplotypes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006239","descriptor_name":"Haplotypes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008285","descriptor_name":"Major Histocompatibility Complex","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008285","descriptor_name":"Major Histocompatibility Complex","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008285","descriptor_name":"Major Histocompatibility Complex","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkac997","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac997","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1102/48441635/gkac997.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:36321663","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36321663","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9825418","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9825418","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkac997","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac997","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1102/48441635/gkac997.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Partnerships for the goals","score":0.5400000214576721,"id":"https://metadata.un.org/sdg/17"}],"awards":[{"id":"https://openalex.org/G1051659124","display_name":null,"funder_award_id":"32030020","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7059489686","display_name":null,"funder_award_id":"31961130380","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321133","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4307972748.pdf","grobid_xml":"https://content.openalex.org/works/W4307972748.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1602617322","https://openalex.org/W1994795462","https://openalex.org/W2016409678","https://openalex.org/W2017824838","https://openalex.org/W2045062204","https://openalex.org/W2048781878","https://openalex.org/W2098951833","https://openalex.org/W2101071606","https://openalex.org/W2101357408","https://openalex.org/W2102714321","https://openalex.org/W2104549677","https://openalex.org/W2111743367","https://openalex.org/W2122732537","https://openalex.org/W2123249685","https://openalex.org/W2150056019","https://openalex.org/W2178823664","https://openalex.org/W2214699570","https://openalex.org/W2522993044","https://openalex.org/W2587446936","https://openalex.org/W2605820408","https://openalex.org/W2619107506","https://openalex.org/W2766579229","https://openalex.org/W2796069077","https://openalex.org/W2859605380","https://openalex.org/W2898301137","https://openalex.org/W2898371836","https://openalex.org/W2977882294","https://openalex.org/W2982254257","https://openalex.org/W2984055282","https://openalex.org/W2987502822","https://openalex.org/W3017134138","https://openalex.org/W3131055609","https://openalex.org/W3170509422","https://openalex.org/W3189929141","https://openalex.org/W3195033491","https://openalex.org/W3203889005","https://openalex.org/W4252667516","https://openalex.org/W6770113330","https://openalex.org/W6770221991","https://openalex.org/W6776198416"],"related_works":["https://openalex.org/W2982533215","https://openalex.org/W2558214260","https://openalex.org/W2010208430","https://openalex.org/W1995509397","https://openalex.org/W2959145910","https://openalex.org/W2951453167","https://openalex.org/W2071887209","https://openalex.org/W4234789023","https://openalex.org/W1673949914","https://openalex.org/W4307972748"],"abstract_inverted_index":{"The":[0,179],"human":[1,8],"leukocyte":[2],"antigen":[3],"(HLA)":[4],"system,":[5],"or":[6,187],"the":[7,11,43,46,159,164],"version":[9],"of":[10,28,45,62,94,97,109,169],"major":[12],"histocompatibility":[13],"complex":[14],"(MHC),":[15],"is":[16,182],"known":[17],"for":[18,78,120,135,144],"its":[19],"extreme":[20],"polymorphic":[21],"nature":[22],"and":[23,30,90,103,128,138,152,166,176],"high":[24],"heterogeneity.":[25],"Taking":[26],"advantage":[27],"whole-genome":[29],"whole-exome":[31],"sequencing":[32],"data,":[33],"we":[34,156],"developed":[35],"PGG.MHC":[36,56,72,160,180],"to":[37,41,131],"provide":[38],"a":[39],"platform":[40],"explore":[42],"diversity":[44,172],"MHC":[47,170],"in":[48,53,173],"Asia":[49],"as":[50,52],"well":[51],"global":[54],"populations.":[55],"currently":[57],"archives":[58],"high-resolution":[59],"HLA":[60,81,98,122,145],"alleles":[61,99,123],"53":[63],"254":[64],"samples":[65],"representing":[66],"190":[67],"populations":[68],"spanning":[69],"66":[70],"countries.":[71],"provides:":[73],"(i)":[74],"high-quality":[75,149],"allele":[76],"frequencies":[77],"eight":[79],"classical":[80],"loci":[82],"(HLA-A,":[83],"-B,":[84],"-C,":[85],"-DQA1,":[86],"-DQB1,":[87],"-DRB1,":[88],"-DPA1":[89],"-DPB1);":[91],"(ii)":[92],"visualization":[93],"population":[95],"prevalence":[96],"on":[100],"global,":[101],"regional,":[102],"country-wide":[104],"levels;":[105],"(iii)":[106],"haplotype":[107],"structure":[108],"134":[110],"populations;":[111],"(iv)":[112],"two":[113],"online":[114],"analysis":[115],"tools":[116],"including":[117],"'HLA":[118,129],"imputation'":[119],"inferring":[121],"from":[124],"SNP":[125],"genotyping":[126],"data":[127,151],"association'":[130],"perform":[132],"case/control":[133],"studies":[134],"HLA-related":[136],"phenotypes":[137],"(v)":[139],"East":[140],"Asian-specific":[141],"reference":[142],"panels":[143],"imputation.":[146],"Equipped":[147],"with":[148],"frequency":[150],"user-friendly":[153],"computer":[154],"tools,":[155],"expect":[157],"that":[158],"database":[161,181],"can":[162],"advance":[163],"understanding":[165],"facilitate":[167],"applications":[168],"genomic":[171],"both":[174],"evolutionary":[175],"medical":[177],"studies.":[178],"freely":[183],"accessible":[184],"via":[185],"https://pog.fudan.edu.cn/pggmhc":[186],"https://www.pggmhc.org/pggmhc.":[188]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3}],"updated_date":"2026-03-27T14:29:43.386196","created_date":"2022-11-06T00:00:00"}