{"id":"https://openalex.org/W4310945327","doi":"https://doi.org/10.1093/nar/gkac1085","title":"DrugCentral 2023 extends human clinical data and integrates veterinary drugs","display_name":"DrugCentral 2023 extends human clinical data and integrates veterinary drugs","publication_year":2022,"publication_date":"2022-12-09","ids":{"openalex":"https://openalex.org/W4310945327","doi":"https://doi.org/10.1093/nar/gkac1085","pmid":"https://pubmed.ncbi.nlm.nih.gov/36484092"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkac1085","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac1085","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1276/48441389/gkac1085.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1276/48441389/gkac1085.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001136257","display_name":"Sorin Avram","orcid":"https://orcid.org/0000-0002-4816-7446"},"institutions":[{"id":"https://openalex.org/I58077936","display_name":"Romanian Academy","ror":"https://ror.org/0561n6946","country_code":"RO","type":"archive","lineage":["https://openalex.org/I58077936"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Sorin Avram","raw_affiliation_strings":["Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania"],"affiliations":[{"raw_affiliation_string":"Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania","institution_ids":["https://openalex.org/I58077936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083043970","display_name":"Thomas B. Wilson","orcid":null},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas B Wilson","raw_affiliation_strings":["College of Pharmacy, University of New Mexico Health Sciences Center , 2502 Marble Ave, Albuquerque, NM 87106 , USA"],"affiliations":[{"raw_affiliation_string":"College of Pharmacy, University of New Mexico Health Sciences Center , 2502 Marble Ave, Albuquerque, NM 87106 , USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023930270","display_name":"Ramona Curp\u0103n","orcid":"https://orcid.org/0000-0003-0268-7291"},"institutions":[{"id":"https://openalex.org/I58077936","display_name":"Romanian Academy","ror":"https://ror.org/0561n6946","country_code":"RO","type":"archive","lineage":["https://openalex.org/I58077936"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Ramona Curpan","raw_affiliation_strings":["Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania"],"affiliations":[{"raw_affiliation_string":"Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania","institution_ids":["https://openalex.org/I58077936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059842265","display_name":"Liliana Halip","orcid":"https://orcid.org/0000-0002-2600-0186"},"institutions":[{"id":"https://openalex.org/I58077936","display_name":"Romanian Academy","ror":"https://ror.org/0561n6946","country_code":"RO","type":"archive","lineage":["https://openalex.org/I58077936"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Liliana Halip","raw_affiliation_strings":["Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania"],"affiliations":[{"raw_affiliation_string":"Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania","institution_ids":["https://openalex.org/I58077936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009965452","display_name":"Ana Borota","orcid":"https://orcid.org/0000-0003-1138-8357"},"institutions":[{"id":"https://openalex.org/I58077936","display_name":"Romanian Academy","ror":"https://ror.org/0561n6946","country_code":"RO","type":"archive","lineage":["https://openalex.org/I58077936"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Ana Borota","raw_affiliation_strings":["Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania"],"affiliations":[{"raw_affiliation_string":"Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania","institution_ids":["https://openalex.org/I58077936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072997237","display_name":"Alina Bora","orcid":"https://orcid.org/0000-0002-8526-7024"},"institutions":[{"id":"https://openalex.org/I58077936","display_name":"Romanian Academy","ror":"https://ror.org/0561n6946","country_code":"RO","type":"archive","lineage":["https://openalex.org/I58077936"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Alina Bora","raw_affiliation_strings":["Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania"],"affiliations":[{"raw_affiliation_string":"Department of Computational Chemistry, \u201cCoriolan Dragulescu\u201d Institute of Chemistry , 24 Mihai Viteazu Blvd , Timi\u015foara, Timi\u015f\u00a0 300223 , Romania","institution_ids":["https://openalex.org/I58077936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053220470","display_name":"Cristian Bologa","orcid":"https://orcid.org/0000-0003-2232-4244"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristian\u00a0G Bologa","raw_affiliation_strings":["Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center , 700 Camino de Salud NE, Albuquerque, NM 87106 , USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center , 700 Camino de Salud NE, Albuquerque, NM 87106 , USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031552923","display_name":"Jayme Holmes","orcid":"https://orcid.org/0000-0003-3109-5228"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jayme Holmes","raw_affiliation_strings":["Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center , 700 Camino de Salud NE, Albuquerque, NM 87106 , USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center , 700 Camino de Salud NE, Albuquerque, NM 87106 , USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090676946","display_name":"Jeffrey Knockel","orcid":"https://orcid.org/0009-0006-6239-9725"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Knockel","raw_affiliation_strings":["Department of Computer Science, University of New Mexico , 1901 Redondo S Dr, Albuquerque, NM 87106 , USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of New Mexico , 1901 Redondo S Dr, Albuquerque, NM 87106 , USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076911664","display_name":"Jeremy J. Yang","orcid":"https://orcid.org/0000-0002-1476-6192"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy\u00a0J Yang","raw_affiliation_strings":["Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center , 700 Camino de Salud NE, Albuquerque, NM 87106 , USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center , 700 Camino de Salud NE, Albuquerque, NM 87106 , USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061685157","display_name":"Tudor I. Oprea","orcid":"https://orcid.org/0000-0002-6195-6976"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tudor\u00a0I Oprea","raw_affiliation_strings":["Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center , 700 Camino de Salud NE, Albuquerque, NM 87106 , USA"],"affiliations":[{"raw_affiliation_string":"Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center , 700 Camino de Salud NE, Albuquerque, NM 87106 , USA","institution_ids":["https://openalex.org/I169521973"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5061685157"],"corresponding_institution_ids":["https://openalex.org/I169521973"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":33.4677,"has_fulltext":true,"cited_by_count":83,"citation_normalized_percentile":{"value":0.99891329,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"51","issue":"D1","first_page":"D1276","last_page":"D1287"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12281","display_name":"Animal testing and alternatives","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.9771999716758728,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/veterinary-drugs","display_name":"Veterinary Drugs","score":0.8111743330955505},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.6903026103973389},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.5790877938270569},{"id":"https://openalex.org/keywords/veterinary-drug","display_name":"Veterinary drug","score":0.5621112585067749},{"id":"https://openalex.org/keywords/human-use","display_name":"Human use","score":0.540115237236023},{"id":"https://openalex.org/keywords/pharmacovigilance","display_name":"Pharmacovigilance","score":0.527410626411438},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5002944469451904},{"id":"https://openalex.org/keywords/safety-pharmacology","display_name":"Safety pharmacology","score":0.44146066904067993},{"id":"https://openalex.org/keywords/adverse-effect","display_name":"Adverse effect","score":0.43845856189727783},{"id":"https://openalex.org/keywords/off-label-use","display_name":"Off-label use","score":0.41872361302375793},{"id":"https://openalex.org/keywords/veterinary-medicine","display_name":"Veterinary medicine","score":0.36151331663131714},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3034479022026062},{"id":"https://openalex.org/keywords/biotechnology","display_name":"Biotechnology","score":0.27510499954223633}],"concepts":[{"id":"https://openalex.org/C2909766688","wikidata":"https://www.wikidata.org/wiki/Q2432100","display_name":"Veterinary Drugs","level":2,"score":0.8111743330955505},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.6903026103973389},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5790877938270569},{"id":"https://openalex.org/C2994320889","wikidata":"https://www.wikidata.org/wiki/Q2432100","display_name":"Veterinary drug","level":2,"score":0.5621112585067749},{"id":"https://openalex.org/C3020792226","wikidata":"https://www.wikidata.org/wiki/Q1331083","display_name":"Human use","level":2,"score":0.540115237236023},{"id":"https://openalex.org/C57658597","wikidata":"https://www.wikidata.org/wiki/Q1550789","display_name":"Pharmacovigilance","level":3,"score":0.527410626411438},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5002944469451904},{"id":"https://openalex.org/C2776190711","wikidata":"https://www.wikidata.org/wiki/Q7398663","display_name":"Safety pharmacology","level":3,"score":0.44146066904067993},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.43845856189727783},{"id":"https://openalex.org/C188313352","wikidata":"https://www.wikidata.org/wiki/Q119697","display_name":"Off-label use","level":2,"score":0.41872361302375793},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.36151331663131714},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3034479022026062},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.27510499954223633},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017277","descriptor_name":"Drug Approval","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017277","descriptor_name":"Drug Approval","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017277","descriptor_name":"Drug Approval","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019155","descriptor_name":"Veterinary Drugs","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019155","descriptor_name":"Veterinary Drugs","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019155","descriptor_name":"Veterinary Drugs","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019155","descriptor_name":"Veterinary Drugs","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D019155","descriptor_name":"Veterinary Drugs","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D019155","descriptor_name":"Veterinary Drugs","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D056687","descriptor_name":"Off-Label Use","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D056687","descriptor_name":"Off-Label Use","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D056687","descriptor_name":"Off-Label Use","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkac1085","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac1085","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1276/48441389/gkac1085.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:36484092","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36484092","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9825566","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9825566","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkac1085","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac1085","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1276/48441389/gkac1085.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6299999952316284}],"awards":[{"id":"https://openalex.org/G3395463761","display_name":null,"funder_award_id":"U24 CA224370","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320321010","display_name":"Universiteit Utrecht","ror":"https://ror.org/04pp8hn57"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320338403","display_name":"Common Fund","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4310945327.pdf","grobid_xml":"https://content.openalex.org/works/W4310945327.grobid-xml"},"referenced_works_count":62,"referenced_works":["https://openalex.org/W1935434993","https://openalex.org/W1975147762","https://openalex.org/W1989756416","https://openalex.org/W2028577022","https://openalex.org/W2071879021","https://openalex.org/W2103017472","https://openalex.org/W2121487587","https://openalex.org/W2129370330","https://openalex.org/W2159583324","https://openalex.org/W2164847835","https://openalex.org/W2166119767","https://openalex.org/W2170146596","https://openalex.org/W2171724541","https://openalex.org/W2346834216","https://openalex.org/W2397609778","https://openalex.org/W2537627201","https://openalex.org/W2539985226","https://openalex.org/W2558217333","https://openalex.org/W2558366645","https://openalex.org/W2788451340","https://openalex.org/W2883565265","https://openalex.org/W2897805491","https://openalex.org/W2899292521","https://openalex.org/W2900090807","https://openalex.org/W2924533776","https://openalex.org/W2987002164","https://openalex.org/W2993935441","https://openalex.org/W2994844251","https://openalex.org/W3004919484","https://openalex.org/W3016161809","https://openalex.org/W3030158388","https://openalex.org/W3034228022","https://openalex.org/W3044273225","https://openalex.org/W3082453120","https://openalex.org/W3086427314","https://openalex.org/W3094762523","https://openalex.org/W3095380161","https://openalex.org/W3096653525","https://openalex.org/W3097145107","https://openalex.org/W3112376646","https://openalex.org/W3112902030","https://openalex.org/W3125935675","https://openalex.org/W3140107645","https://openalex.org/W3162629392","https://openalex.org/W3164371899","https://openalex.org/W3164771895","https://openalex.org/W3185323030","https://openalex.org/W3196689514","https://openalex.org/W3199031620","https://openalex.org/W3209896479","https://openalex.org/W4205177117","https://openalex.org/W4210702584","https://openalex.org/W4210766095","https://openalex.org/W4220784339","https://openalex.org/W4281673562","https://openalex.org/W4294576509","https://openalex.org/W4295048769","https://openalex.org/W6683960167","https://openalex.org/W6760402595","https://openalex.org/W6770567329","https://openalex.org/W6771048758","https://openalex.org/W6800429005"],"related_works":["https://openalex.org/W2417248516","https://openalex.org/W4386741625","https://openalex.org/W2357765815","https://openalex.org/W3175102709","https://openalex.org/W3048189846","https://openalex.org/W206883478","https://openalex.org/W3169410899","https://openalex.org/W2392762993","https://openalex.org/W2886763278","https://openalex.org/W3024058471"],"abstract_inverted_index":{"DrugCentral":[0],"monitors":[1],"new":[2],"drug":[3,7,47],"approvals":[4],"and":[5,41,54,65,91,97,105,118,154,193],"standardizes":[6],"information.":[8],"The":[9],"current":[10],"update":[11],"contains":[12],"285":[13],"drugs":[14,27,84,87,101,112,133,144,174],"(131":[15],"for":[16,29,52,135,148,164,191],"human":[17,149,181],"use).":[18],"New":[19],"additions":[20],"include:":[21],"(i)":[22,79],"the":[23,34,43,77,82,111,122,125,142,159,168,187],"integration":[24],"of":[25,36,45,74,81,110,124,131,141,172,180],"veterinary":[26,143,165],"(154":[28],"animal":[30,136,173],"use":[31,137],"only),":[32],"(ii)":[33,108],"addition":[35],"66":[37],"documented":[38],"off-label":[39],"uses":[40],"iii)":[42],"identification":[44],"adverse":[46],"events":[48],"from":[49],"pharmacovigilance":[50],"data":[51],"pediatric":[53],"geriatric":[55],"patients.":[56],"Additional":[57],"enhancements":[58],"include":[59,76,185],"chemical":[60],"substructure":[61],"searching":[62],"using":[63],"SMILES":[64],"'Target":[66],"Cards'":[67],"based":[68],"on":[69],"UniProt":[70],"accession":[71],"codes.":[72],"Statistics":[73],"interests":[75],"following:":[78],"60%":[80],"covered":[83],"are":[85,95,99,113,116,134,145,156],"on-market":[86,100],"with":[88,102],"expired":[89],"patent":[90],"exclusivity":[92,106],"coverage,":[93],"17%":[94],"off-market,":[96],"23%":[98],"active":[103,126],"patents":[104],"coverage;":[107],"59%":[109],"oral,":[114],"33%":[115],"parenteral":[117],"18%":[119],"topical,":[120],"at":[121],"level":[123],"ingredients;":[127],"(iii)":[128],"only":[129,188],"3%":[130],"all":[132],"only;":[138],"however,":[139],"61%":[140],"also":[146],"approved":[147,190],"use;":[150],"(iv)":[151],"dogs,":[152],"cats":[153],"horses":[155],"by":[157],"far":[158],"most":[160],"represented":[161],"target":[162],"species":[163],"drugs;":[166],"(v)":[167],"physicochemical":[169],"property":[170],"profile":[171],"is":[175],"very":[176],"similar":[177],"to":[178],"that":[179],"drugs.":[182],"Use":[183],"cases":[184],"azaperone,":[186],"sedative":[189],"swine,":[192],"ruxolitinib,":[194],"a":[195],"Janus":[196],"kinase":[197],"inhibitor.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":30},{"year":2024,"cited_by_count":30},{"year":2023,"cited_by_count":20}],"updated_date":"2026-03-05T09:29:38.588285","created_date":"2025-10-10T00:00:00"}