{"id":"https://openalex.org/W3199031620","doi":"https://doi.org/10.1093/nar/gkab850","title":"COVID19db: a comprehensive database platform to discover potential drugs and targets of COVID-19 at whole transcriptomic scale","display_name":"COVID19db: a comprehensive database platform to discover potential drugs and targets of COVID-19 at whole transcriptomic scale","publication_year":2021,"publication_date":"2021-09-11","ids":{"openalex":"https://openalex.org/W3199031620","doi":"https://doi.org/10.1093/nar/gkab850","mag":"3199031620","pmid":"https://pubmed.ncbi.nlm.nih.gov/34554255"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkab850","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab850","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/nar/gkab850","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100689217","display_name":"Wenliang Zhang","orcid":"https://orcid.org/0000-0003-0454-6935"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210141719","display_name":"University of Hong Kong - Shenzhen Hospital","ror":"https://ror.org/047w7d678","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141719"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":true,"raw_author_name":"Wenliang Zhang","raw_affiliation_strings":["Department of Bioinformatics, Outstanding Biotechnology Co., Ltd.-Shenzhen, Shenzhen, China","Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Outstanding Biotechnology Co., Ltd.-Shenzhen, Shenzhen, China","institution_ids":[]},{"raw_affiliation_string":"Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","institution_ids":["https://openalex.org/I889458895","https://openalex.org/I4210141719"]},{"raw_affiliation_string":"Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100456161","display_name":"Yan Zhang","orcid":"https://orcid.org/0000-0001-8919-1269"},"institutions":[{"id":"https://openalex.org/I4210141719","display_name":"University of Hong Kong - Shenzhen Hospital","ror":"https://ror.org/047w7d678","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141719"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Yan Zhang","raw_affiliation_strings":["Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China"],"affiliations":[{"raw_affiliation_string":"Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","institution_ids":["https://openalex.org/I889458895","https://openalex.org/I4210141719"]},{"raw_affiliation_string":"Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042224248","display_name":"Zhuochao Min","orcid":null},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuochao Min","raw_affiliation_strings":["School of Information and Software Engineering, University of Electronic Science and Technology of China, Chengdu\u00a0610054, China"],"affiliations":[{"raw_affiliation_string":"School of Information and Software Engineering, University of Electronic Science and Technology of China, Chengdu\u00a0610054, China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055710591","display_name":"Jing Mo","orcid":"https://orcid.org/0000-0002-5341-2995"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jing Mo","raw_affiliation_strings":["Department of Bioinformatics, Outstanding Biotechnology Co., Ltd.-Shenzhen, Shenzhen, China"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Outstanding Biotechnology Co., Ltd.-Shenzhen, Shenzhen, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062830066","display_name":"Zhen Ju","orcid":"https://orcid.org/0000-0001-7720-1570"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhen Ju","raw_affiliation_strings":["CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","Center for High Performance Computing, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Center for High Performance Computing, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109347073","display_name":"Wen Guan","orcid":"https://orcid.org/0000-0001-7349-0555"},"institutions":[{"id":"https://openalex.org/I4210167311","display_name":"Institute of Zoology","ror":"https://ror.org/05skxkv18","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311"]},{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen Guan","raw_affiliation_strings":["Department of Bioinformatics, Outstanding Biotechnology Co., Ltd.-Shenzhen, Shenzhen, China","Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Institute of Zoology, Guangdong Academy of Sciences, Guangzhou\u00a0510260, China"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Outstanding Biotechnology Co., Ltd.-Shenzhen, Shenzhen, China","institution_ids":[]},{"raw_affiliation_string":"Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Institute of Zoology, Guangdong Academy of Sciences, Guangzhou\u00a0510260, China","institution_ids":["https://openalex.org/I4210167311","https://openalex.org/I4210103524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065419788","display_name":"Binghui Zeng","orcid":"https://orcid.org/0000-0003-4770-7014"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210132950","display_name":"Stomatology Hospital","ror":"https://ror.org/041yj5753","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210132950"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Binghui Zeng","raw_affiliation_strings":["Department of Bioinformatics, Outstanding Biotechnology Co., Ltd.-Shenzhen, Shenzhen, China","Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou\u00a0510055, China"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Outstanding Biotechnology Co., Ltd.-Shenzhen, Shenzhen, China","institution_ids":[]},{"raw_affiliation_string":"Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou\u00a0510055, China","institution_ids":["https://openalex.org/I4210132950","https://openalex.org/I157773358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100356037","display_name":"Yang Liu","orcid":"https://orcid.org/0000-0002-9442-700X"},"institutions":[{"id":"https://openalex.org/I4210141719","display_name":"University of Hong Kong - Shenzhen Hospital","ror":"https://ror.org/047w7d678","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141719"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Yang Liu","raw_affiliation_strings":["Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China"],"affiliations":[{"raw_affiliation_string":"Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","institution_ids":["https://openalex.org/I889458895","https://openalex.org/I4210141719"]},{"raw_affiliation_string":"Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101880354","display_name":"Jianliang Chen","orcid":"https://orcid.org/0000-0003-3780-3889"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]},{"id":"https://openalex.org/I4210141719","display_name":"University of Hong Kong - Shenzhen Hospital","ror":"https://ror.org/047w7d678","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141719"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Jianliang Chen","raw_affiliation_strings":["Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China"],"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","institution_ids":["https://openalex.org/I889458895","https://openalex.org/I4210141719"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043639879","display_name":"Qianshen Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210141719","display_name":"University of Hong Kong - Shenzhen Hospital","ror":"https://ror.org/047w7d678","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141719"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Qianshen Zhang","raw_affiliation_strings":["Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China"],"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","institution_ids":["https://openalex.org/I889458895","https://openalex.org/I4210141719"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075888100","display_name":"Hanguang Li","orcid":"https://orcid.org/0000-0001-7171-0032"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]},{"id":"https://openalex.org/I4210141719","display_name":"University of Hong Kong - Shenzhen Hospital","ror":"https://ror.org/047w7d678","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141719"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Hanguang Li","raw_affiliation_strings":["Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China"],"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","institution_ids":["https://openalex.org/I889458895","https://openalex.org/I4210141719"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103053586","display_name":"Chun\u2010Xia Zeng","orcid":"https://orcid.org/0000-0002-0823-8406"},"institutions":[{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunxia Zeng","raw_affiliation_strings":["CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","Center for High Performance Computing, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Center for High Performance Computing, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037823825","display_name":"Yanjie Wei","orcid":"https://orcid.org/0000-0002-4791-7540"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yanjie Wei","raw_affiliation_strings":["CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","Center for High Performance Computing, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Center for High Performance Computing, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Shenzhen Institute\u00a0of\u00a0Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong\u00a0518055, China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018585615","display_name":"Gcf Chan","orcid":"https://orcid.org/0000-0001-5032-8985"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]},{"id":"https://openalex.org/I4210141719","display_name":"University of Hong Kong - Shenzhen Hospital","ror":"https://ror.org/047w7d678","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141719"]}],"countries":["CN","HK"],"is_corresponding":true,"raw_author_name":"Godfrey Chi-Fung Chan","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong\u00a0999077, China","Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China"],"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong\u00a0999077, China","institution_ids":["https://openalex.org/I889458895"]},{"raw_affiliation_string":"Department of Pediatrics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong\u00a0518053, China","institution_ids":["https://openalex.org/I889458895","https://openalex.org/I4210141719"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5018585615","https://openalex.org/A5037823825","https://openalex.org/A5100689217"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210141719","https://openalex.org/I4210145761","https://openalex.org/I889458895"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":2.4066,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.91024474,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"50","issue":"D1","first_page":"D747","last_page":"D757"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.9850000143051147,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8745434880256653},{"id":"https://openalex.org/keywords/coronavirus-disease-2019","display_name":"Coronavirus disease 2019 (COVID-19)","score":0.6850980520248413},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.6658684015274048},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.567846953868866},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5522307753562927},{"id":"https://openalex.org/keywords/2019-20-coronavirus-outbreak","display_name":"2019-20 coronavirus outbreak","score":0.4976942837238312},{"id":"https://openalex.org/keywords/severe-acute-respiratory-syndrome-coronavirus-2","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","score":0.4833473861217499},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.22603347897529602},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.19679120182991028},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.10314503312110901},{"id":"https://openalex.org/keywords/infectious-disease","display_name":"Infectious disease (medical specialty)","score":0.10091426968574524},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.08877816796302795},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.08561435341835022}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8745434880256653},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.6850980520248413},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.6658684015274048},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.567846953868866},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5522307753562927},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.4976942837238312},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.4833473861217499},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.22603347897529602},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19679120182991028},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10314503312110901},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.10091426968574524},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08877816796302795},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.08561435341835022},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000093485","descriptor_name":"COVID-19 Drug Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000093485","descriptor_name":"COVID-19 Drug Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000093485","descriptor_name":"COVID-19 Drug Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkab850","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab850","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:34554255","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34554255","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8728200","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8728200","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkab850","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab850","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1144551320","display_name":null,"funder_award_id":"SZSM201911016","funder_id":"https://openalex.org/F4320335767","funder_display_name":"Sanming Project of Medicine in Shenzhen"},{"id":"https://openalex.org/G168641028","display_name":null,"funder_award_id":"32100513","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4587599806","display_name":null,"funder_award_id":"2018YFB0204403","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G6738523828","display_name":null,"funder_award_id":"2021M693302","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320335767","display_name":"Sanming Project of Medicine in Shenzhen","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W2096525273","https://openalex.org/W2162151166","https://openalex.org/W2559588208","https://openalex.org/W2950595506","https://openalex.org/W3016393661","https://openalex.org/W3030537287","https://openalex.org/W3034228022","https://openalex.org/W3034883465","https://openalex.org/W3036778916","https://openalex.org/W3037020655","https://openalex.org/W3042950801","https://openalex.org/W3045143182","https://openalex.org/W3045802278","https://openalex.org/W3045931208","https://openalex.org/W3047366767","https://openalex.org/W3048259608","https://openalex.org/W3049166744","https://openalex.org/W3081918364","https://openalex.org/W3082849942","https://openalex.org/W3082869193","https://openalex.org/W3085958090","https://openalex.org/W3092040438","https://openalex.org/W3092453176","https://openalex.org/W3095380161","https://openalex.org/W3096723079","https://openalex.org/W3096967708","https://openalex.org/W3111061871","https://openalex.org/W3112656922","https://openalex.org/W3117520605","https://openalex.org/W3118810627","https://openalex.org/W3120634523","https://openalex.org/W3131767541","https://openalex.org/W3134078202","https://openalex.org/W3135833838","https://openalex.org/W3137172923","https://openalex.org/W3152817622","https://openalex.org/W3162339789","https://openalex.org/W3162783054","https://openalex.org/W3165796371","https://openalex.org/W3167140978","https://openalex.org/W3171370271","https://openalex.org/W4205247356","https://openalex.org/W4247001379","https://openalex.org/W6796469873"],"related_works":["https://openalex.org/W3036314732","https://openalex.org/W3009669391","https://openalex.org/W3176864053","https://openalex.org/W4206669628","https://openalex.org/W3171943759","https://openalex.org/W4292098121","https://openalex.org/W3154141118","https://openalex.org/W4388896133","https://openalex.org/W3031607536","https://openalex.org/W3198183218"],"abstract_inverted_index":{"Many":[0],"open":[1],"access":[2],"transcriptomic":[3,154],"data":[4,25,89,187],"of":[5,29,69,81,158,196],"coronavirus":[6],"disease":[7],"2019":[8],"(COVID-19)":[9],"were":[10],"generated,":[11],"they":[12],"have":[13],"great":[14],"heterogeneity":[15],"and":[16,61,84,95,124,129,150,163,168,184],"are":[17],"difficult":[18],"to":[19,109,121,132,146,179],"analyze.":[20],"To":[21,87],"utilize":[22],"these":[23],"invaluable":[24],"for":[26,37,126,170,188],"better":[27],"understanding":[28],"COVID-19,":[30],"additional":[31],"software":[32],"should":[33],"be":[34],"developed.":[35],"Especially":[36],"researchers":[38,120],"without":[39],"bioinformatic":[40],"skills,":[41],"a":[42,140],"user-friendly":[43,176],"platform":[44,51,102],"is":[45,144],"mandatory.":[46],"We":[47],"developed":[48],"the":[49,79,116,194],"COVID19db":[50,162,174],"(http://hpcc.siat.ac.cn/covid19db":[52],"&":[53],"http://www.biomedical-web.com/covid19db)":[54],"that":[55],"provides":[56,104,175],"39":[57],"930":[58],"drug-target-pathway":[59],"interactions":[60],"95":[62],"COVID-19":[63],"related":[64],"datasets,":[65],"which":[66],"include":[67],"transcriptomes":[68],"4127":[70],"human":[71],"samples":[72],"across":[73],"13":[74],"body":[75],"sites":[76],"associated":[77],"with":[78,97],"exposure":[80],"33":[82,85],"microbes":[83],"drugs/agents.":[86],"facilitate":[88],"application,":[90],"each":[91],"dataset":[92],"was":[93],"standardized":[94],"annotated":[96],"rich":[98],"clinical":[99],"information.":[100],"The":[101],"further":[103,189],"14":[105,117],"different":[106,127],"analytical":[107],"applications":[108,118],"analyze":[110],"various":[111],"mechanisms":[112],"underlying":[113],"COVID-19.":[114,171,200],"Moreover,":[115],"enable":[119],"customize":[122],"grouping":[123],"setting":[125],"analyses":[128,134],"allow":[130],"them":[131],"perform":[133],"using":[135],"their":[136],"own":[137],"data.":[138],"Furthermore,":[139],"Drug":[141],"Discovery":[142],"tool":[143],"designed":[145],"identify":[147],"potential":[148,166],"drugs":[149,167],"targets":[151,169],"at":[152],"whole":[153],"scale.":[155],"For":[156],"proof":[157],"concept,":[159],"we":[160],"used":[161],"identified":[164],"multiple":[165],"In":[172],"summary,":[173],"web":[177],"interfaces":[178],"freely":[180],"analyze,":[181],"download":[182],"data,":[183],"submit":[185],"new":[186],"integration,":[190],"it":[191],"can":[192],"accelerate":[193],"identification":[195],"effective":[197],"strategies":[198],"against":[199]},"counts_by_year":[{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}
