{"id":"https://openalex.org/W3168771278","doi":"https://doi.org/10.1093/nar/gkab449","title":"DGLinker: flexible knowledge-graph prediction of disease\u2013gene associations","display_name":"DGLinker: flexible knowledge-graph prediction of disease\u2013gene associations","publication_year":2021,"publication_date":"2021-05-18","ids":{"openalex":"https://openalex.org/W3168771278","doi":"https://doi.org/10.1093/nar/gkab449","mag":"3168771278","pmid":"https://pubmed.ncbi.nlm.nih.gov/34125897"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkab449","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab449","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/nar/gkab449","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030977043","display_name":"Jiajing Hu","orcid":null},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jiajing Hu","raw_affiliation_strings":["Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT,\u00a0UK","Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London,\u00a0SE5 8AF, London, UK","Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT, UK,","Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE5 8AF, London, UK,"],"affiliations":[{"raw_affiliation_string":"Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT,\u00a0UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London,\u00a0SE5 8AF, London, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT, UK,","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE5 8AF, London, UK,","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057595671","display_name":"Rosalba Lepore","orcid":"https://orcid.org/0000-0002-9481-2557"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Rosalba Lepore","raw_affiliation_strings":["BSC-CNS Barcelona Supercomputing Center, Barcelona, 08034,\u00a0Spain","BSC-CNS Barcelona Supercomputing Center, Barcelona, 08034, Spain,"],"affiliations":[{"raw_affiliation_string":"BSC-CNS Barcelona Supercomputing Center, Barcelona, 08034,\u00a0Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]},{"raw_affiliation_string":"BSC-CNS Barcelona Supercomputing Center, Barcelona, 08034, Spain,","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066918469","display_name":"Richard Dobson","orcid":"https://orcid.org/0000-0003-4224-9245"},"institutions":[{"id":"https://openalex.org/I124357947","display_name":"University of London","ror":"https://ror.org/04cw6st05","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210142469","display_name":"Health Data Research UK","ror":"https://ror.org/04rtjaj74","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210142469"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard J B Dobson","raw_affiliation_strings":["Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London,\u00a0SE5 8AF, London, UK","Health Data Research UK London, University College London, London, WC1E 6BT,\u00a0UK","Institute of Health Informatics, University College London, London, NW1 2DA,\u00a0UK","Institute of Health Informatics, University College London, London, NW1 2DA, UK,","Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE5 8AF, London, UK,","Health Data Research UK London, University College London, London, WC1E 6BT, UK,"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London,\u00a0SE5 8AF, London, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Health Data Research UK London, University College London, London, WC1E 6BT,\u00a0UK","institution_ids":["https://openalex.org/I4210142469","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute of Health Informatics, University College London, London, NW1 2DA,\u00a0UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute of Health Informatics, University College London, London, NW1 2DA, UK,","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE5 8AF, London, UK,","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Health Data Research UK London, University College London, London, WC1E 6BT, UK,","institution_ids":["https://openalex.org/I4210142469","https://openalex.org/I45129253","https://openalex.org/I124357947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038119270","display_name":"Ammar Al\u2010Chalabi","orcid":"https://orcid.org/0000-0002-4924-7712"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210153400","display_name":"King's College Hospital","ror":"https://ror.org/044nptt90","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ammar Al-Chalabi","raw_affiliation_strings":["Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT,\u00a0UK","King\u2032s College Hospital, Bessemer Road, Denmark Hill, London, SE5 9RS, UK","Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT, UK,","King s College Hospital, Bessemer Road, Denmark Hill, London, SE5 9RS, UK and"],"affiliations":[{"raw_affiliation_string":"Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT,\u00a0UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"King\u2032s College Hospital, Bessemer Road, Denmark Hill, London, SE5 9RS, UK","institution_ids":["https://openalex.org/I4210153400"]},{"raw_affiliation_string":"Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT, UK,","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"King s College Hospital, Bessemer Road, Denmark Hill, London, SE5 9RS, UK and","institution_ids":["https://openalex.org/I4210153400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013929782","display_name":"Daniel Bean","orcid":"https://orcid.org/0000-0002-8594-7804"},"institutions":[{"id":"https://openalex.org/I124357947","display_name":"University of London","ror":"https://ror.org/04cw6st05","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210142469","display_name":"Health Data Research UK","ror":"https://ror.org/04rtjaj74","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210142469"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Daniel M.\u00a0Bean","raw_affiliation_strings":["Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London,\u00a0SE5 8AF, London, UK","Health Data Research UK London, University College London, London, WC1E 6BT,\u00a0UK","Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE5 8AF, London, UK,","Health Data Research UK London, University College London, London, WC1E 6BT, UK,"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London,\u00a0SE5 8AF, London, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Health Data Research UK London, University College London, London, WC1E 6BT,\u00a0UK","institution_ids":["https://openalex.org/I4210142469","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE5 8AF, London, UK,","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Health Data Research UK London, University College London, London, WC1E 6BT, UK,","institution_ids":["https://openalex.org/I4210142469","https://openalex.org/I45129253","https://openalex.org/I124357947"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013893534","display_name":"Alfredo Iacoangeli","orcid":"https://orcid.org/0000-0002-5280-5017"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I200323923","display_name":"South London and Maudsley NHS Foundation Trust","ror":"https://ror.org/015803449","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I200323923"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I4391767825","display_name":"NIHR Biomedical Research Centre at The Royal Marsden and the ICR","ror":"https://ror.org/014ktry78","country_code":null,"type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616","https://openalex.org/I34931013","https://openalex.org/I4391767825"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Alfredo Iacoangeli","raw_affiliation_strings":["Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT,\u00a0UK","Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London,\u00a0SE5 8AF, London, UK","National Institute for Health Research Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust and King's College London, London, SE5 8AF,\u00a0UK","Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT, UK,","Maudsley NHS Foundation Trust and King's College London, London, SE5 8AF, UK","Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE5 8AF, London, UK,"],"affiliations":[{"raw_affiliation_string":"Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT,\u00a0UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London,\u00a0SE5 8AF, London, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"National Institute for Health Research Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust and King's College London, London, SE5 8AF,\u00a0UK","institution_ids":["https://openalex.org/I200323923","https://openalex.org/I183935753","https://openalex.org/I34931013","https://openalex.org/I4391767825"]},{"raw_affiliation_string":"Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RT, UK,","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Maudsley NHS Foundation Trust and King's College London, London, SE5 8AF, UK","institution_ids":["https://openalex.org/I200323923","https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE5 8AF, London, UK,","institution_ids":["https://openalex.org/I183935753"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5013893534"],"corresponding_institution_ids":["https://openalex.org/I183935753","https://openalex.org/I200323923","https://openalex.org/I34931013","https://openalex.org/I4391767825"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":2.0289,"has_fulltext":true,"cited_by_count":35,"citation_normalized_percentile":{"value":0.87501781,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"49","issue":"W1","first_page":"W153","last_page":"W161"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exploit","display_name":"Exploit","score":0.7349483370780945},{"id":"https://openalex.org/keywords/upload","display_name":"Upload","score":0.7101858854293823},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6511583924293518},{"id":"https://openalex.org/keywords/web-server","display_name":"Web server","score":0.5956708192825317},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5062686204910278},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.43673136830329895},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3973424434661865},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.21413016319274902},{"id":"https://openalex.org/keywords/the-internet","display_name":"The Internet","score":0.18528017401695251}],"concepts":[{"id":"https://openalex.org/C165696696","wikidata":"https://www.wikidata.org/wiki/Q11287","display_name":"Exploit","level":2,"score":0.7349483370780945},{"id":"https://openalex.org/C71901391","wikidata":"https://www.wikidata.org/wiki/Q7126699","display_name":"Upload","level":2,"score":0.7101858854293823},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6511583924293518},{"id":"https://openalex.org/C11392498","wikidata":"https://www.wikidata.org/wiki/Q11288","display_name":"Web server","level":3,"score":0.5956708192825317},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5062686204910278},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.43673136830329895},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3973424434661865},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.21413016319274902},{"id":"https://openalex.org/C110875604","wikidata":"https://www.wikidata.org/wiki/Q75","display_name":"The Internet","level":2,"score":0.18528017401695251},{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.0},{"id":"https://openalex.org/C55352822","wikidata":"https://www.wikidata.org/wiki/Q5558978","display_name":"Gibbs isotherm","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1093/nar/gkab449","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab449","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:34125897","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34125897","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:upcommons.upc.edu:2117/350393","is_oa":true,"landing_page_url":"https://hdl.handle.net/2117/350393","pdf_url":"http://hdl.handle.net/2117/350393","source":{"id":"https://openalex.org/S4210207057","display_name":"QRU Quaderns de Recerca en Urbanisme","issn_l":"2014-9689","issn":["2014-9689","2385-6777"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4310322448","host_organization_name":"Q71272178","host_organization_lineage":["https://openalex.org/P4310322448"],"host_organization_lineage_names":["Q71272178"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10131297","is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10131297/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"   Nucleic Acids Research , 49  (W1)   W153-W161.   (2021)      ","raw_type":"Article"},{"id":"pmh:oai:iris.uniroma1.it:11573/1680051","is_oa":true,"landing_page_url":"https://hdl.handle.net/11573/1680051","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8262728","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8262728","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkab449","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab449","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2813660310","display_name":null,"funder_award_id":"633413","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G4060705982","display_name":null,"funder_award_id":"MR/S00310X/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4557674082","display_name":null,"funder_award_id":"MR/R024804/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4657563902","display_name":null,"funder_award_id":"MR/R024804/1","funder_id":"https://openalex.org/F4320314158","funder_display_name":"EU Joint Programme \u2013 Neurodegenerative Disease Research"},{"id":"https://openalex.org/G6258312832","display_name":null,"funder_award_id":"MR/L501529/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7376789991","display_name":null,"funder_award_id":"MC_PC_17214","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7419370404","display_name":null,"funder_award_id":"MR/L501529/1","funder_id":"https://openalex.org/F4320314158","funder_display_name":"EU Joint Programme \u2013 Neurodegenerative Disease Research"},{"id":"https://openalex.org/G796254908","display_name":null,"funder_award_id":"ES/L008238/1","funder_id":"https://openalex.org/F4320334630","funder_display_name":"Economic and Social Research Council"},{"id":"https://openalex.org/G945599103","display_name":null,"funder_award_id":"MR/S00310X/1","funder_id":"https://openalex.org/F4320314731","funder_display_name":"UK Research and Innovation"}],"funders":[{"id":"https://openalex.org/F4320311198","display_name":"South London and Maudsley NHS Foundation Trust","ror":"https://ror.org/015803449"},{"id":"https://openalex.org/F4320312999","display_name":"MND Scotland","ror":null},{"id":"https://openalex.org/F4320314158","display_name":"EU Joint Programme \u2013 Neurodegenerative Disease Research","ror":null},{"id":"https://openalex.org/F4320314731","display_name":"UK Research and Innovation","ror":"https://ror.org/001aqnf71"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320108","display_name":"Motor Neurone Disease Association","ror":"https://ror.org/02gq0fg61"},{"id":"https://openalex.org/F4320322725","display_name":"China Scholarship Council","ror":"https://ror.org/04atp4p48"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334630","display_name":"Economic and Social Research Council","ror":"https://ror.org/03n0ht308"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W954754213","https://openalex.org/W1894493322","https://openalex.org/W1978592341","https://openalex.org/W1985213868","https://openalex.org/W1989277387","https://openalex.org/W1995683190","https://openalex.org/W2007178835","https://openalex.org/W2018219462","https://openalex.org/W2018838463","https://openalex.org/W2037442572","https://openalex.org/W2040678584","https://openalex.org/W2043764521","https://openalex.org/W2050335693","https://openalex.org/W2052685738","https://openalex.org/W2058320302","https://openalex.org/W2062584010","https://openalex.org/W2079031049","https://openalex.org/W2092123736","https://openalex.org/W2096525273","https://openalex.org/W2098023402","https://openalex.org/W2103017472","https://openalex.org/W2109506073","https://openalex.org/W2110551795","https://openalex.org/W2117886681","https://openalex.org/W2119412782","https://openalex.org/W2122718339","https://openalex.org/W2124100711","https://openalex.org/W2124649657","https://openalex.org/W2137434543","https://openalex.org/W2142237411","https://openalex.org/W2142879323","https://openalex.org/W2154866190","https://openalex.org/W2155723007","https://openalex.org/W2162151166","https://openalex.org/W2164683872","https://openalex.org/W2164771218","https://openalex.org/W2183415660","https://openalex.org/W2283806265","https://openalex.org/W2537623931","https://openalex.org/W2537679995","https://openalex.org/W2559028527","https://openalex.org/W2725805506","https://openalex.org/W2749613778","https://openalex.org/W2769065924","https://openalex.org/W2770026599","https://openalex.org/W2845591014","https://openalex.org/W2899197140","https://openalex.org/W2899728356","https://openalex.org/W2912663010","https://openalex.org/W2915536738","https://openalex.org/W2915705246","https://openalex.org/W2942188819","https://openalex.org/W2951352223","https://openalex.org/W2972577058","https://openalex.org/W2983166786","https://openalex.org/W3017302094","https://openalex.org/W3027261607","https://openalex.org/W3031191781","https://openalex.org/W3036097568","https://openalex.org/W3095102107","https://openalex.org/W3096828292","https://openalex.org/W3106811464","https://openalex.org/W3107500297","https://openalex.org/W3112376646","https://openalex.org/W3112600195","https://openalex.org/W3211402536","https://openalex.org/W4231254854","https://openalex.org/W4236135856","https://openalex.org/W4243601081","https://openalex.org/W6813094581"],"related_works":["https://openalex.org/W1496222301","https://openalex.org/W3207760230","https://openalex.org/W1590307681","https://openalex.org/W4312814274","https://openalex.org/W4285370786","https://openalex.org/W2358353312","https://openalex.org/W2353836703","https://openalex.org/W41015297","https://openalex.org/W2909040123","https://openalex.org/W4234342421"],"abstract_inverted_index":{"As":[0],"a":[1,79,92,100,112,128],"result":[2],"of":[3,6,17,30,42,45,56,84,94,115],"the":[4,18,27,39,71,82,147,168],"advent":[5],"high-throughput":[7],"technologies,":[8],"there":[9],"has":[10,33,99],"been":[11,36],"rapid":[12],"progress":[13],"in":[14],"our":[15,53],"understanding":[16,55],"genetics":[19,58],"underlying":[20],"biological":[21,46,116],"processes.":[22],"However,":[23],"despite":[24],"such":[25],"advances,":[26],"genetic":[28,67],"landscape":[29],"human":[31,89],"diseases":[32,90],"only":[34],"marginally":[35],"disclosed.":[37],"Exploiting":[38],"present":[40],"availability":[41],"large":[43],"amounts":[44],"and":[47,117,130,145,149,162],"phenotypic":[48,118],"data,":[49,125],"we":[50,76],"can":[51],"use":[52,131],"current":[54],"disease":[57,96],"to":[59,64,107,121,126,134,143,164],"train":[60],"machine":[61,132],"learning":[62,133],"models":[63],"predict":[65,135],"novel":[66,85],"factors":[68],"associated":[69],"with":[70],"disease.":[72],"To":[73],"this":[74],"end,":[75],"developed":[77],"DGLinker,":[78],"webserver":[80,140,159],"for":[81,88,170],"prediction":[83],"candidate":[86],"genes":[87],"given":[91],"set":[93],"known":[95],"genes.":[97,138],"DGLinker":[98,153],"user-friendly":[101],"interface":[102],"that":[103],"allows":[104],"non-expert":[105],"users":[106,166],"exploit":[108],"biomedical":[109],"information":[110],"from":[111],"wide":[113],"range":[114],"databases,":[119],"and/or":[120],"upload":[122],"their":[123],"own":[124],"generate":[127],"knowledge-graph":[129],"new":[136],"disease-associated":[137],"The":[139,158],"includes":[141],"tools":[142],"explore":[144],"interpret":[146],"results":[148],"generates":[150],"publication-ready":[151],"figures.":[152],"is":[154,160],"available":[155],"at":[156],"https://dglinker.rosalind.kcl.ac.uk.":[157],"free":[161],"open":[163],"all":[165],"without":[167],"need":[169],"registration.":[171]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":4}],"updated_date":"2026-03-27T14:29:43.386196","created_date":"2025-10-10T00:00:00"}