{"id":"https://openalex.org/W3164271582","doi":"https://doi.org/10.1093/nar/gkab447","title":"KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis","display_name":"KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis","publication_year":2021,"publication_date":"2021-05-09","ids":{"openalex":"https://openalex.org/W3164271582","doi":"https://doi.org/10.1093/nar/gkab447","mag":"3164271582","pmid":"https://pubmed.ncbi.nlm.nih.gov/34086934"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkab447","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab447","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W317/38842244/gkab447.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/49/W1/W317/38842244/gkab447.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089019310","display_name":"Dechao Bu","orcid":"https://orcid.org/0000-0002-8833-5432"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dechao Bu","raw_affiliation_strings":["Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China"],"affiliations":[{"raw_affiliation_string":"Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066262854","display_name":"Haitao Luo","orcid":"https://orcid.org/0000-0003-3671-7786"},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haitao Luo","raw_affiliation_strings":["Translational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen 518020, China"],"affiliations":[{"raw_affiliation_string":"Translational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen 518020, China","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031007522","display_name":"Peipei Huo","orcid":"https://orcid.org/0000-0003-4508-4036"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peipei Huo","raw_affiliation_strings":["Chinese Academy of Sciences, LuoYang Branch of Institute of Computing Technology, Luoyang, 471000,\u00a0China"],"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, LuoYang Branch of Institute of Computing Technology, Luoyang, 471000,\u00a0China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037999253","display_name":"Zhihao Wang","orcid":"https://orcid.org/0000-0002-3533-7805"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhihao Wang","raw_affiliation_strings":["Chinese Academy of Sciences, LuoYang Branch of Institute of Computing Technology, Luoyang, 471000,\u00a0China"],"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, LuoYang Branch of Institute of Computing Technology, Luoyang, 471000,\u00a0China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100325428","display_name":"Shan Zhang","orcid":"https://orcid.org/0009-0009-4050-4063"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shan Zhang","raw_affiliation_strings":["Chinese Academy of Sciences, LuoYang Branch of Institute of Computing Technology, Luoyang, 471000,\u00a0China"],"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, LuoYang Branch of Institute of Computing Technology, Luoyang, 471000,\u00a0China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075390894","display_name":"Zihao He","orcid":"https://orcid.org/0000-0001-6588-1169"},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zihao He","raw_affiliation_strings":["School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ChaoYang District, Beijing 100029, China"],"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ChaoYang District, Beijing 100029, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059651530","display_name":"Yang Wu","orcid":"https://orcid.org/0000-0001-6547-9524"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Wu","raw_affiliation_strings":["Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China"],"affiliations":[{"raw_affiliation_string":"Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010222360","display_name":"Lianhe Zhao","orcid":"https://orcid.org/0000-0002-7736-2443"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lianhe Zhao","raw_affiliation_strings":["Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China"],"affiliations":[{"raw_affiliation_string":"Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069470888","display_name":"Jingjia Liu","orcid":"https://orcid.org/0000-0001-6490-3135"},"institutions":[{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingjia Liu","raw_affiliation_strings":["Cancer Center, Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Zhejiang 315000, China"],"affiliations":[{"raw_affiliation_string":"Cancer Center, Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Zhejiang 315000, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042914048","display_name":"Jincheng Guo","orcid":"https://orcid.org/0000-0002-5616-6910"},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jincheng Guo","raw_affiliation_strings":["School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ChaoYang District, Beijing 100029, China"],"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ChaoYang District, Beijing 100029, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054273034","display_name":"Shuangsang Fang","orcid":null},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuangsang Fang","raw_affiliation_strings":["School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ChaoYang District, Beijing 100029, China"],"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ChaoYang District, Beijing 100029, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008758302","display_name":"Wanchen Cao","orcid":null},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanchen Cao","raw_affiliation_strings":["School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ChaoYang District, Beijing 100029, China"],"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ChaoYang District, Beijing 100029, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113509614","display_name":"Lan Yi","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lan Yi","raw_affiliation_strings":["Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China"],"affiliations":[{"raw_affiliation_string":"Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000991048","display_name":"Yi Zhao","orcid":"https://orcid.org/0000-0001-6046-8420"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yi Zhao","raw_affiliation_strings":["Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China"],"affiliations":[{"raw_affiliation_string":"Pervasive Computing Research Center, Institute of Computing Technology, Chinese Academy ofSciences, Beijing, 100190, China","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024297841","display_name":"Lei Kong","orcid":"https://orcid.org/0000-0003-1162-2158"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lei Kong","raw_affiliation_strings":["Center for Bioinformatics, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing 100871, China"],"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing 100871, China","institution_ids":["https://openalex.org/I20231570"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5000991048","https://openalex.org/A5024297841"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I20231570","https://openalex.org/I4210090176"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":136.8136,"has_fulltext":false,"cited_by_count":1901,"citation_normalized_percentile":{"value":0.99989782,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"49","issue":"W1","first_page":"W317","last_page":"W325"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9779000282287598,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.7558563351631165},{"id":"https://openalex.org/keywords/timeline","display_name":"Timeline","score":0.6987268924713135},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6338567733764648},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.6001093983650208},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5827292203903198},{"id":"https://openalex.org/keywords/prioritization","display_name":"Prioritization","score":0.5491837859153748},{"id":"https://openalex.org/keywords/class","display_name":"Class (philosophy)","score":0.5353411436080933},{"id":"https://openalex.org/keywords/exploratory-analysis","display_name":"Exploratory analysis","score":0.5312823057174683},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5094550251960754},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.46846693754196167},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.451596200466156},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3291899561882019},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.31994667649269104},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2887169420719147},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.169573575258255},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.16913029551506042},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.14540520310401917}],"concepts":[{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.7558563351631165},{"id":"https://openalex.org/C4438859","wikidata":"https://www.wikidata.org/wiki/Q186117","display_name":"Timeline","level":2,"score":0.6987268924713135},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6338567733764648},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.6001093983650208},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5827292203903198},{"id":"https://openalex.org/C2777615720","wikidata":"https://www.wikidata.org/wiki/Q11888847","display_name":"Prioritization","level":2,"score":0.5491837859153748},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.5353411436080933},{"id":"https://openalex.org/C3018260909","wikidata":"https://www.wikidata.org/wiki/Q1322871","display_name":"Exploratory analysis","level":2,"score":0.5312823057174683},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5094550251960754},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46846693754196167},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.451596200466156},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3291899561882019},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.31994667649269104},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2887169420719147},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.169573575258255},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.16913029551506042},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.14540520310401917},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C539667460","wikidata":"https://www.wikidata.org/wiki/Q2414942","display_name":"Management science","level":1,"score":0.0},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkab447","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab447","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W317/38842244/gkab447.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:34086934","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34086934","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8265193","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8265193","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkab447","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab447","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W317/38842244/gkab447.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6100000143051147,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G6632869965","display_name":null,"funder_award_id":"2017YFC0908404","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7536392352","display_name":null,"funder_award_id":"32070670","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3164271582.pdf","grobid_xml":"https://content.openalex.org/works/W3164271582.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W1518152488","https://openalex.org/W1977813572","https://openalex.org/W1989277387","https://openalex.org/W2020859582","https://openalex.org/W2027847170","https://openalex.org/W2035310028","https://openalex.org/W2035618305","https://openalex.org/W2038963685","https://openalex.org/W2057015734","https://openalex.org/W2060880575","https://openalex.org/W2060987350","https://openalex.org/W2087243986","https://openalex.org/W2096086497","https://openalex.org/W2097948046","https://openalex.org/W2100980426","https://openalex.org/W2102992354","https://openalex.org/W2104097656","https://openalex.org/W2105106534","https://openalex.org/W2108096229","https://openalex.org/W2110256992","https://openalex.org/W2110687686","https://openalex.org/W2118069309","https://openalex.org/W2120474334","https://openalex.org/W2124649657","https://openalex.org/W2129099812","https://openalex.org/W2130410032","https://openalex.org/W2133465414","https://openalex.org/W2139036189","https://openalex.org/W2148590574","https://openalex.org/W2158384363","https://openalex.org/W2159707944","https://openalex.org/W2160313295","https://openalex.org/W2164998314","https://openalex.org/W2165232124","https://openalex.org/W2223505479","https://openalex.org/W2345356016","https://openalex.org/W2559588208","https://openalex.org/W2611604995","https://openalex.org/W2749464300","https://openalex.org/W2768714097","https://openalex.org/W2804476515","https://openalex.org/W2891349395","https://openalex.org/W2928665623","https://openalex.org/W2944226869","https://openalex.org/W2944545583","https://openalex.org/W2946173685","https://openalex.org/W3004747635","https://openalex.org/W3011252852","https://openalex.org/W3020992812","https://openalex.org/W3110917833","https://openalex.org/W3112600195","https://openalex.org/W4231254854","https://openalex.org/W6631086861","https://openalex.org/W6813094581"],"related_works":["https://openalex.org/W1858249912","https://openalex.org/W2114034199","https://openalex.org/W4391249598","https://openalex.org/W2317428717","https://openalex.org/W2734259032","https://openalex.org/W3094038556","https://openalex.org/W2014772881","https://openalex.org/W4254228154","https://openalex.org/W3049477255","https://openalex.org/W4296345146"],"abstract_inverted_index":{"Gene":[0],"set":[1],"enrichment":[2],"(GSE)":[3],"analysis":[4],"plays":[5],"an":[6,153],"essential":[7],"role":[8],"in":[9,131],"extracting":[10],"biological":[11,97],"insight":[12],"from":[13,148],"genome-scale":[14],"experiments.":[15],"ORA":[16,49],"(overrepresentation":[17],"analysis),":[18],"FCS":[19,81],"(functional":[20],"class":[21],"scoring),":[22],"and":[23,83,92,110,128,183],"PT":[24,85],"(pathway":[25],"topology)":[26],"approaches":[27],"are":[28],"three":[29],"generations":[30],"of":[31,37,41,56,121,145],"GSE":[32],"methods":[33],"along":[34],"the":[35,48,95,104,112,137,143,172],"timeline":[36],"development.":[38],"Previous":[39],"versions":[40],"KOBAS":[42,64,101,141,176],"provided":[43],"services":[44],"based":[45,135],"on":[46,136],"just":[47],"method.":[50],"Here":[51],"we":[52,74],"presented":[53],"version":[54],"3.0":[55],"KOBAS,":[57],"which":[58,78,123],"is":[59,187],"named":[60],"KOBAS-i":[61],"(short":[62],"for":[63,108],"intelligent":[65],"version).":[66],"It":[67],"introduced":[68],"a":[69,88,118,132,160,169,184],"novel":[70,119],"machine":[71],"learning-based":[72],"method":[73],"published":[75],"earlier,":[76],"CGPS,":[77],"incorporates":[79],"seven":[80],"tools":[82,86],"two":[84],"into":[87],"single":[89],"ensemble":[90],"score":[91],"intelligently":[93],"prioritizes":[94],"relevant":[96],"pathways.":[98],"In":[99],"addition,":[100],"has":[102],"expanded":[103],"downstream":[105],"exploratory":[106],"visualization":[107],"selecting":[109],"understanding":[111],"enriched":[113,126],"results.":[114],"The":[115],"tool":[116],"constructs":[117],"view":[120],"cirFunMap,":[122],"presents":[124],"different":[125],"terms":[127],"their":[129],"correlations":[130],"landscape.":[133],"Finally,":[134],"previous":[138],"version's":[139],"framework,":[140],"increased":[142],"number":[144],"supported":[146],"species":[147],"1327":[149],"to":[150,171],"5944.":[151],"For":[152],"easier":[154],"local":[155],"run,":[156],"it":[157],"also":[158],"provides":[159],"prebuilt":[161],"Docker":[162],"image":[163],"that":[164],"requires":[165],"no":[166],"installation,":[167],"as":[168],"supplementary":[170],"source":[173],"code":[174],"version.":[175],"can":[177],"be":[178],"freely":[179],"accessed":[180],"at":[181,189],"http://kobas.cbi.pku.edu.cn,":[182],"mirror":[185],"site":[186],"available":[188],"http://bioinfo.org/kobas.":[190]},"counts_by_year":[{"year":2026,"cited_by_count":111},{"year":2025,"cited_by_count":425},{"year":2024,"cited_by_count":600},{"year":2023,"cited_by_count":433},{"year":2022,"cited_by_count":299},{"year":2021,"cited_by_count":30}],"updated_date":"2026-04-04T08:04:53.788161","created_date":"2025-10-10T00:00:00"}