{"id":"https://openalex.org/W3165069396","doi":"https://doi.org/10.1093/nar/gkab424","title":"Thunor: visualization and analysis of high-throughput dose\u2013response datasets","display_name":"Thunor: visualization and analysis of high-throughput dose\u2013response datasets","publication_year":2021,"publication_date":"2021-05-04","ids":{"openalex":"https://openalex.org/W3165069396","doi":"https://doi.org/10.1093/nar/gkab424","mag":"3165069396","pmid":"https://pubmed.ncbi.nlm.nih.gov/34038546"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkab424","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab424","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W633/38842457/gkab424.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/49/W1/W633/38842457/gkab424.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032663621","display_name":"Alexander L. R. Lubbock","orcid":"https://orcid.org/0000-0002-6950-8908"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander L R Lubbock","raw_affiliation_strings":["Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010400772","display_name":"Leonard A. Harris","orcid":"https://orcid.org/0000-0003-2112-6940"},"institutions":[{"id":"https://openalex.org/I4210129634","display_name":"Winthrop Rockefeller Foundation","ror":"https://ror.org/02pqmy074","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210129634"]},{"id":"https://openalex.org/I78715868","display_name":"University of Arkansas at Fayetteville","ror":"https://ror.org/05jbt9m15","country_code":"US","type":"education","lineage":["https://openalex.org/I78715868"]},{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leonard A Harris","raw_affiliation_strings":["Cancer Biology Program, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, 72205,\u00a0USA","Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR, 72701,\u00a0USA","Interdisciplinary Graduate Program in Cell and Molecular Biology, University of Arkansas, Fayetteville, AR,\u00a072701,\u00a0USA"],"affiliations":[{"raw_affiliation_string":"Cancer Biology Program, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, 72205,\u00a0USA","institution_ids":["https://openalex.org/I4210129634","https://openalex.org/I79620101"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR, 72701,\u00a0USA","institution_ids":["https://openalex.org/I78715868"]},{"raw_affiliation_string":"Interdisciplinary Graduate Program in Cell and Molecular Biology, University of Arkansas, Fayetteville, AR,\u00a072701,\u00a0USA","institution_ids":["https://openalex.org/I78715868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003212140","display_name":"Vito Quaranta","orcid":"https://orcid.org/0000-0001-7491-8672"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vito Quaranta","raw_affiliation_strings":["Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA","Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061250244","display_name":"Darren R. Tyson","orcid":"https://orcid.org/0000-0002-3272-4308"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Darren R Tyson","raw_affiliation_strings":["Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070306403","display_name":"Carlos F. Lopez","orcid":"https://orcid.org/0000-0003-3668-7468"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Carlos F Lopez","raw_affiliation_strings":["Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232,\u00a0USA","Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232,\u00a0USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37232,\u00a0USA","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5070306403"],"corresponding_institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":0.4879,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.6165666,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"49","issue":"W1","first_page":"W633","last_page":"W640"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/upload","display_name":"Upload","score":0.7083244919776917},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.6936924457550049},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6039583086967468},{"id":"https://openalex.org/keywords/graphical-user-interface","display_name":"Graphical user interface","score":0.588367223739624},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.5669939517974854},{"id":"https://openalex.org/keywords/throughput","display_name":"Throughput","score":0.5369766354560852},{"id":"https://openalex.org/keywords/categorical-variable","display_name":"Categorical variable","score":0.5282425284385681},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.47520169615745544},{"id":"https://openalex.org/keywords/interactive-visualization","display_name":"Interactive visualization","score":0.46688714623451233},{"id":"https://openalex.org/keywords/drug-response","display_name":"Drug response","score":0.44286850094795227},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.41806453466415405},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.40966492891311646},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3967844545841217},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.36242008209228516},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.33449453115463257},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.15623760223388672},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.14588358998298645},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.11404058337211609}],"concepts":[{"id":"https://openalex.org/C71901391","wikidata":"https://www.wikidata.org/wiki/Q7126699","display_name":"Upload","level":2,"score":0.7083244919776917},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.6936924457550049},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6039583086967468},{"id":"https://openalex.org/C37789001","wikidata":"https://www.wikidata.org/wiki/Q782543","display_name":"Graphical user interface","level":2,"score":0.588367223739624},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.5669939517974854},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.5369766354560852},{"id":"https://openalex.org/C5274069","wikidata":"https://www.wikidata.org/wiki/Q2285707","display_name":"Categorical variable","level":2,"score":0.5282425284385681},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.47520169615745544},{"id":"https://openalex.org/C64073096","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Interactive visualization","level":3,"score":0.46688714623451233},{"id":"https://openalex.org/C2994119904","wikidata":"https://www.wikidata.org/wiki/Q1251001","display_name":"Drug response","level":3,"score":0.44286850094795227},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.41806453466415405},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40966492891311646},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3967844545841217},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.36242008209228516},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33449453115463257},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.15623760223388672},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.14588358998298645},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.11404058337211609},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkab424","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab424","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W633/38842457/gkab424.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:34038546","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34038546","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8265171","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8265171","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkab424","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab424","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W633/38842457/gkab424.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5400000214576721}],"awards":[{"id":"https://openalex.org/G1498527648","display_name":null,"funder_award_id":"1411482","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G1673755842","display_name":null,"funder_award_id":"U01CA215845","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1990786686","display_name":null,"funder_award_id":"1942255","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3065513951","display_name":null,"funder_award_id":"U54CA217450","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4703316244","display_name":null,"funder_award_id":"T15-LM007450","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G5342635511","display_name":null,"funder_award_id":"R50CA243783","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6319874090","display_name":null,"funder_award_id":"K22CA237857","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6553593135","display_name":null,"funder_award_id":"CA217450","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7524497307","display_name":null,"funder_award_id":"5T15-LM007450-14","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G7872770252","display_name":null,"funder_award_id":"W911 NF-14-2-0022","funder_id":"https://openalex.org/F4320332180","funder_display_name":"Defense Advanced Research Projects Agency"},{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309151","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34"},{"id":"https://openalex.org/F4320332180","display_name":"Defense Advanced Research Projects Agency","ror":"https://ror.org/02caytj08"},{"id":"https://openalex.org/F4320332815","display_name":"Advanced Research Projects Agency","ror":"https://ror.org/02caytj08"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337372","display_name":"U.S. National Library of Medicine","ror":"https://ror.org/0060t0j89"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3165069396.pdf","grobid_xml":"https://content.openalex.org/works/W3165069396.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1512337159","https://openalex.org/W1979739874","https://openalex.org/W2005660297","https://openalex.org/W2031441006","https://openalex.org/W2108068107","https://openalex.org/W2112046350","https://openalex.org/W2122859071","https://openalex.org/W2125789330","https://openalex.org/W2152883907","https://openalex.org/W2212640525","https://openalex.org/W2256578114","https://openalex.org/W2344714812","https://openalex.org/W2345299709","https://openalex.org/W2554439427","https://openalex.org/W2621616899","https://openalex.org/W2759360483","https://openalex.org/W2944727022","https://openalex.org/W3041851038","https://openalex.org/W3103634428","https://openalex.org/W6678465990"],"related_works":["https://openalex.org/W2944823289","https://openalex.org/W3037018281","https://openalex.org/W2972592048","https://openalex.org/W2358319515","https://openalex.org/W4386799044","https://openalex.org/W4321854979","https://openalex.org/W2003209439","https://openalex.org/W2497626292","https://openalex.org/W4312214821","https://openalex.org/W4361862506"],"abstract_inverted_index":{"High-throughput":[0],"cell":[1,61,87,111,123,142,182],"proliferation":[2,62,70,88,189],"assays":[3,71],"to":[4,54,137,167],"quantify":[5],"drug-response":[6],"are":[7,40,107],"becoming":[8],"increasingly":[9],"common":[10],"and":[11,19,35,38,57,68,83,93,113,119,145,169,185],"powerful":[12],"with":[13,80,141,154],"the":[14,163],"emergence":[15],"of":[16,28,86,165],"improved":[17],"automation":[18],"multi-time":[20],"point":[21],"analysis":[22,27],"methods.":[23],"However,":[24],"pipelines":[25],"for":[26,110,116],"these":[29],"datasets":[30,101],"that":[31],"provide":[32],"reproducible,":[33],"efficient,":[34],"interactive":[36,81],"visualization":[37,118],"interpretation":[39],"sorely":[41],"lacking.":[42],"To":[43],"address":[44],"this":[45],"need,":[46],"we":[47],"introduce":[48],"Thunor,":[49],"an":[50,186],"open-source":[51],"software":[52],"platform":[53],"manage,":[55],"analyze,":[56],"visualize":[58],"large,":[59,179],"dose-dependent":[60],"datasets.":[63],"Thunor":[64,166,192],"supports":[65],"both":[66],"end-point":[67],"time-based":[69],"as":[72],"input.":[73],"It":[74],"provides":[75],"a":[76,178],"simple,":[77],"user-friendly":[78],"interface":[79],"plots":[82],"publication-quality":[84],"images":[85],"time":[89],"courses,":[90],"dose-response":[91,95],"curves,":[92],"derived":[94],"metrics,":[96],"e.g.":[97,122],"IC50,":[98],"including":[99],"across":[100],"or":[102,126],"grouped":[103],"by":[104],"tags.":[105],"Tags":[106],"categorical":[108],"labels":[109],"lines":[112],"drugs,":[114],"used":[115],"aggregation,":[117],"statistical":[120],"analysis,":[121],"line":[124],"mutation":[125],"drug":[127,175],"class/target":[128],"pathway.":[129],"A":[130],"graphical":[131],"plate":[132,139],"map":[133],"tool":[134],"is":[135,193],"included":[136],"facilitate":[138],"annotation":[140],"lines,":[143],"drugs":[144],"concentrations":[146],"upon":[147],"data":[148],"upload.":[149],"Datasets":[150],"can":[151],"be":[152],"shared":[153],"other":[155],"users":[156],"via":[157],"point-and-click":[158],"access":[159],"control.":[160],"We":[161],"demonstrate":[162],"utility":[164],"examine":[168],"gain":[170],"insight":[171],"from":[172,195],"two":[173],"large":[174],"response":[176],"datasets:":[177],"publicly":[180],"available":[181,194],"viability":[183],"database":[184],"in-house,":[187],"high-throughput":[188],"rate":[190],"dataset.":[191],"www.thunor.net.":[196]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}