{"id":"https://openalex.org/W3158388427","doi":"https://doi.org/10.1093/nar/gkab327","title":"LipidSuite: interactive web server for lipidomics differential and enrichment analysis","display_name":"LipidSuite: interactive web server for lipidomics differential and enrichment analysis","publication_year":2021,"publication_date":"2021-04-20","ids":{"openalex":"https://openalex.org/W3158388427","doi":"https://doi.org/10.1093/nar/gkab327","mag":"3158388427","pmid":"https://pubmed.ncbi.nlm.nih.gov/33950258"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkab327","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab327","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W346/38841981/gkab327.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/49/W1/W346/38841981/gkab327.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038054571","display_name":"Ahmed Mohamed","orcid":"https://orcid.org/0000-0001-6507-5300"},"institutions":[{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Ahmed Mohamed","raw_affiliation_strings":["Precision & Systems Biomedicine Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD\u00a04006, Australia"],"affiliations":[{"raw_affiliation_string":"Precision & Systems Biomedicine Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD\u00a04006, Australia","institution_ids":["https://openalex.org/I217937681"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070498464","display_name":"Michelle M. Hill","orcid":"https://orcid.org/0000-0003-1134-0951"},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Michelle M Hill","raw_affiliation_strings":["Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD\u00a04006, Australia","Precision & Systems Biomedicine Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD\u00a04006, Australia"],"affiliations":[{"raw_affiliation_string":"Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD\u00a04006, Australia","institution_ids":["https://openalex.org/I165143802"]},{"raw_affiliation_string":"Precision & Systems Biomedicine Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD\u00a04006, Australia","institution_ids":["https://openalex.org/I217937681"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5038054571","https://openalex.org/A5070498464"],"corresponding_institution_ids":["https://openalex.org/I165143802","https://openalex.org/I217937681"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":1.5419,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.82926547,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"49","issue":"W1","first_page":"W346","last_page":"W351"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9757999777793884,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipidomics","display_name":"Lipidomics","score":0.9201434254646301},{"id":"https://openalex.org/keywords/profiling","display_name":"Profiling (computer programming)","score":0.564091682434082},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5142473578453064},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4493003785610199},{"id":"https://openalex.org/keywords/upload","display_name":"Upload","score":0.4250714182853699},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.4202907681465149},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.40200531482696533},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.33018958568573},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.09086403250694275}],"concepts":[{"id":"https://openalex.org/C58017582","wikidata":"https://www.wikidata.org/wiki/Q6556376","display_name":"Lipidomics","level":2,"score":0.9201434254646301},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.564091682434082},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5142473578453064},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4493003785610199},{"id":"https://openalex.org/C71901391","wikidata":"https://www.wikidata.org/wiki/Q7126699","display_name":"Upload","level":2,"score":0.4250714182853699},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4202907681465149},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40200531482696533},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33018958568573},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.09086403250694275},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000081362","descriptor_name":"Lipidomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000081362","descriptor_name":"Lipidomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000081362","descriptor_name":"Lipidomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkab327","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab327","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W346/38841981/gkab327.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:33950258","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33950258","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8262688","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8262688","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkab327","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab327","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W346/38841981/gkab327.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.46000000834465027,"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure"}],"awards":[{"id":"https://openalex.org/G8562819600","display_name":null,"funder_award_id":"DP160100224","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"}],"funders":[{"id":"https://openalex.org/F4320314063","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30"},{"id":"https://openalex.org/F4320334704","display_name":"Australian Research Council","ror":"https://ror.org/05mmh0f86"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3158388427.pdf","grobid_xml":"https://content.openalex.org/works/W3158388427.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1960974681","https://openalex.org/W2083637865","https://openalex.org/W2096769282","https://openalex.org/W2108488321","https://openalex.org/W2146512944","https://openalex.org/W2584556111","https://openalex.org/W2619796081","https://openalex.org/W2735452220","https://openalex.org/W2803664483","https://openalex.org/W2938288400","https://openalex.org/W2949923941","https://openalex.org/W2951837249","https://openalex.org/W3011287221","https://openalex.org/W3014022783","https://openalex.org/W3015253797","https://openalex.org/W3038012174","https://openalex.org/W3102516975","https://openalex.org/W3108211199","https://openalex.org/W6869068519"],"related_works":["https://openalex.org/W2017497567","https://openalex.org/W2804498896","https://openalex.org/W2091512523","https://openalex.org/W4238045650","https://openalex.org/W2117748922","https://openalex.org/W2004558801","https://openalex.org/W2806559730","https://openalex.org/W2416426346","https://openalex.org/W4323826842","https://openalex.org/W2883516315"],"abstract_inverted_index":{"Advances":[0],"in":[1,78,82],"mass":[2],"spectrometry":[3],"enabled":[4],"high":[5],"throughput":[6],"profiling":[7],"of":[8,16,48],"lipids":[9],"but":[10],"differential":[11,30,43,160],"analysis":[12,33,44,47,79,163],"and":[13,45,50,69,96,116,120,127,138,164,166],"biological":[14,169],"interpretation":[15,170],"lipidomics":[17,31,54,161,172],"datasets":[18],"remains":[19],"challenging.":[20],"To":[21],"overcome":[22],"this":[23,154],"barrier,":[24],"we":[25,152],"present":[26],"LipidSuite,":[27],"an":[28],"end-to-end":[29],"data":[32,55,136,162],"server.":[34],"LipidSuite":[35,130,174],"offers":[36,131],"a":[37,70,83],"step-by-step":[38],"workflow":[39],"for":[40,59,147],"preprocessing,":[41],"exploration,":[42],"enrichment":[46],"untargeted":[49],"targeted":[51],"lipidomics.":[52],"Three":[53],"formats":[56],"are":[57,80,89],"accepted":[58],"upload:":[60],"mwTab":[61],"file":[62],"from":[63,171],"Metabolomics":[64],"Workbench,":[65],"Skyline":[66],"CSV":[67],"Export,":[68],"numerical":[71],"matrix.":[72],"Experimental":[73],"variables":[74,133],"to":[75,92,158],"be":[76,141],"used":[77],"uploaded":[81],"separate":[84],"file.":[85],"Conventional":[86],"lipid":[87,94,112],"names":[88],"automatically":[90],"parsed":[91],"enable":[93],"class":[95],"chain":[97],"length":[98],"analyses.":[99,122],"Users":[100],"can":[101,140],"interactively":[102,143],"explore":[103],"data,":[104],"choose":[105],"subsets":[106],"based":[107],"on":[108],"sample":[109],"types":[110],"or":[111,114,145,149],"classes":[113],"characteristics,":[115],"conduct":[117],"univariate,":[118],"multivariate":[119],"unsupervised":[121],"For":[123],"complex":[124],"experimental":[125],"designs":[126],"clinical":[128],"cohorts,":[129],"confounding":[132],"adjustment.":[134],"Finally,":[135],"tables":[137],"plots":[139],"both":[142],"viewed":[144],"downloaded":[146],"publication":[148],"reports.":[150],"Overall,":[151],"anticipate":[153],"free,":[155],"user-friendly":[156],"webserver":[157],"facilitate":[159],"re-analysis,":[165],"fully":[167],"harness":[168],"datasets.":[173],"is":[175],"freely":[176],"available":[177],"at":[178],"http://suite.lipidr.org.":[179]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}