{"id":"https://openalex.org/W3162037110","doi":"https://doi.org/10.1093/nar/gkab300","title":"ReFOLD3: refinement of 3D protein models with gradual restraints based on predicted local quality and residue contacts","display_name":"ReFOLD3: refinement of 3D protein models with gradual restraints based on predicted local quality and residue contacts","publication_year":2021,"publication_date":"2021-04-17","ids":{"openalex":"https://openalex.org/W3162037110","doi":"https://doi.org/10.1093/nar/gkab300","mag":"3162037110","pmid":"https://pubmed.ncbi.nlm.nih.gov/34009387"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkab300","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab300","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W589/38841989/gkab300.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/49/W1/W589/38841989/gkab300.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005444909","display_name":"Recep Adiyaman","orcid":"https://orcid.org/0000-0001-8124-5381"},"institutions":[{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Recep Adiyaman","raw_affiliation_strings":["School of Biological Sciences, University of Reading, Whiteknights, Reading RG6 6AS, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, University of Reading, Whiteknights, Reading RG6 6AS, UK","institution_ids":["https://openalex.org/I71052956"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067569944","display_name":"Liam J. McGuffin","orcid":"https://orcid.org/0000-0003-4501-4767"},"institutions":[{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Liam J McGuffin","raw_affiliation_strings":["School of Biological Sciences, University of Reading, Whiteknights, Reading RG6 6AS, UK"],"raw_orcid":"https://orcid.org/0000-0003-4501-4767","affiliations":[{"raw_affiliation_string":"School of Biological Sciences, University of Reading, Whiteknights, Reading RG6 6AS, UK","institution_ids":["https://openalex.org/I71052956"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5067569944"],"corresponding_institution_ids":["https://openalex.org/I71052956"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":1.2584,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.7894352,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"49","issue":"W1","first_page":"W589","last_page":"W596"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9876999855041504,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/casp","display_name":"CASP","score":0.8006795644760132},{"id":"https://openalex.org/keywords/protocol","display_name":"Protocol (science)","score":0.6846317052841187},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5275582671165466},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4879555106163025},{"id":"https://openalex.org/keywords/quality-score","display_name":"Quality Score","score":0.4826372265815735},{"id":"https://openalex.org/keywords/quality","display_name":"Quality (philosophy)","score":0.45407259464263916},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.43459370732307434},{"id":"https://openalex.org/keywords/iterative-refinement","display_name":"Iterative refinement","score":0.4113515019416809},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"Protein structure prediction","score":0.3702414035797119},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.2883222997188568},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.2116430103778839},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.10030880570411682}],"concepts":[{"id":"https://openalex.org/C66153294","wikidata":"https://www.wikidata.org/wiki/Q899291","display_name":"CASP","level":4,"score":0.8006795644760132},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.6846317052841187},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5275582671165466},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4879555106163025},{"id":"https://openalex.org/C2779346075","wikidata":"https://www.wikidata.org/wiki/Q7268763","display_name":"Quality Score","level":3,"score":0.4826372265815735},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.45407259464263916},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.43459370732307434},{"id":"https://openalex.org/C2779982483","wikidata":"https://www.wikidata.org/wiki/Q6094420","display_name":"Iterative refinement","level":2,"score":0.4113515019416809},{"id":"https://openalex.org/C18051474","wikidata":"https://www.wikidata.org/wiki/Q899656","display_name":"Protein structure prediction","level":3,"score":0.3702414035797119},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2883222997188568},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.2116430103778839},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10030880570411682},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.0},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D003201","descriptor_name":"Computers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003201","descriptor_name":"Computers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003201","descriptor_name":"Computers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/nar/gkab300","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab300","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W589/38841989/gkab300.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:34009387","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34009387","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:centaur.reading.ac.uk:97497","is_oa":true,"landing_page_url":"https://centaur.reading.ac.uk/view/creators/90010773.html>","pdf_url":"https://centaur.reading.ac.uk/97497/8/gkab300.pdf","source":{"id":"https://openalex.org/S4306402273","display_name":"CentAUR (University of Reading)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I71052956","host_organization_name":"University of Reading","host_organization_lineage":["https://openalex.org/I71052956"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8218204","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8218204","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkab300","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab300","pdf_url":"https://academic.oup.com/nar/article-pdf/49/W1/W589/38841989/gkab300.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/4","score":0.6200000047683716,"display_name":"Quality Education"}],"awards":[{"id":"https://openalex.org/G5366331781","display_name":null,"funder_award_id":"BB/T018496/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G8136038317","display_name":"Advancing capability in high performance protein structure and function prediction through optimisation of IntFOLD","funder_award_id":"BB/T018496/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3162037110.pdf","grobid_xml":"https://content.openalex.org/works/W3162037110.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1785767033","https://openalex.org/W1976499671","https://openalex.org/W1994941561","https://openalex.org/W1998917415","https://openalex.org/W2004822259","https://openalex.org/W2018820972","https://openalex.org/W2018840610","https://openalex.org/W2035018017","https://openalex.org/W2041793332","https://openalex.org/W2052328791","https://openalex.org/W2060872117","https://openalex.org/W2099565782","https://openalex.org/W2102245393","https://openalex.org/W2110510374","https://openalex.org/W2136799255","https://openalex.org/W2138755951","https://openalex.org/W2140673705","https://openalex.org/W2141718854","https://openalex.org/W2145991251","https://openalex.org/W2150981663","https://openalex.org/W2158562723","https://openalex.org/W2161605421","https://openalex.org/W2167661287","https://openalex.org/W2344557669","https://openalex.org/W2409640637","https://openalex.org/W2555870966","https://openalex.org/W2598827021","https://openalex.org/W2606769899","https://openalex.org/W2609811411","https://openalex.org/W2754054476","https://openalex.org/W2766793957","https://openalex.org/W2770647690","https://openalex.org/W2944347827","https://openalex.org/W2960589734","https://openalex.org/W2964644761","https://openalex.org/W2977360892","https://openalex.org/W2980272550","https://openalex.org/W2999044305","https://openalex.org/W3027442799"],"related_works":["https://openalex.org/W2411998238","https://openalex.org/W3198923619","https://openalex.org/W2093959518","https://openalex.org/W2334085108","https://openalex.org/W3199799076","https://openalex.org/W2561391236","https://openalex.org/W1599064615","https://openalex.org/W2147472674","https://openalex.org/W3199104097","https://openalex.org/W2155201844"],"abstract_inverted_index":{"ReFOLD3":[0,34,104,153,186],"is":[1,189],"unique":[2],"in":[3,60,136,143],"its":[4],"application":[5],"of":[6,25,109,161,168,180],"gradual":[7],"restraints,":[8],"calculated":[9],"from":[10],"local":[11,50,91,129],"model":[12,68],"quality":[13,69,92,130],"estimates":[14],"and":[15,49,55,90,116,128,174],"contact":[16],"predictions,":[17],"which":[18,57,86],"are":[19,58,82],"used":[20,102,157],"to":[21,44,78,106,148],"guide":[22],"the":[23,31,61,74,79,95,103,114,117,126,137,144,149,159,162,169,181],"refinement":[24,42,115,138,160],"theoretical":[26],"3D":[27,110],"protein":[28],"models":[29,63,81,135],"towards":[30],"native":[32],"structures.":[33],"achieves":[35],"improved":[36,125],"performance":[37],"by":[38,64,84],"using":[39],"an":[40],"iterative":[41],"protocol":[43,105,154],"fix":[45],"incorrect":[46],"residue":[47],"contacts":[48],"errors,":[51],"including":[52],"unusual":[53],"bonds":[54],"angles,":[56],"identified":[59],"submitted":[62,80],"our":[65],"leading":[66],"ModFOLD8":[67],"assessment":[70],"method.":[71],"Following":[72],"refinement,":[73],"likely":[75],"resulting":[76],"improvements":[77],"recognized":[83],"ModFOLD8,":[85],"produces":[87],"both":[88,113],"global":[89,127],"estimates.":[93],"During":[94],"CASP14":[96],"prediction":[97,121],"season":[98],"(May-Aug":[99],"2020),":[100],"we":[101,141,175],"refine":[107],"hundreds":[108],"models,":[111],"for":[112,132,158],"main":[118],"tertiary":[119],"structure":[120],"categories.":[122],"Our":[123],"group":[124],"scores":[131],"numerous":[133],"starting":[134],"category,":[139],"where":[140],"ranked":[142],"top":[145,182],"10":[146,183],"according":[147],"official":[150],"assessment.":[151],"The":[152,185],"was":[155],"also":[156],"SARS-CoV-2":[163],"targets":[164],"as":[165],"a":[166,177],"part":[167],"CASP":[170],"Commons":[171],"COVID-19":[172],"initiative,":[173],"provided":[176],"significant":[178],"number":[179],"models.":[184],"web":[187],"server":[188],"freely":[190],"available":[191],"at":[192],"https://www.reading.ac.uk/bioinf/ReFOLD/.":[193]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-07-15T18:14:33.161393","created_date":"2025-10-10T00:00:00"}