{"id":"https://openalex.org/W3216494066","doi":"https://doi.org/10.1093/nar/gkab1106","title":"eQuilibrator 3.0: a database solution for thermodynamic constant estimation","display_name":"eQuilibrator 3.0: a database solution for thermodynamic constant estimation","publication_year":2021,"publication_date":"2021-10-21","ids":{"openalex":"https://openalex.org/W3216494066","doi":"https://doi.org/10.1093/nar/gkab1106","mag":"3216494066","pmid":"https://pubmed.ncbi.nlm.nih.gov/34850162"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkab1106","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab1106","pdf_url":"https://academic.oup.com/nar/article-pdf/50/D1/D603/42057662/gkab1106.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/50/D1/D603/42057662/gkab1106.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019729791","display_name":"Moritz E. Beber","orcid":"https://orcid.org/0000-0003-2406-1978"},"institutions":[{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]},{"id":"https://openalex.org/I96673099","display_name":"Technical University of Denmark","ror":"https://ror.org/04qtj9h94","country_code":"DK","type":"education","lineage":["https://openalex.org/I96673099"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Moritz E Beber","raw_affiliation_strings":["Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, 2800 Kongens Lyngby, Denmark","Unseen Biometrics ApS, Fruebjergvej 3, 2100\u00a0K\u00f8benhavn \u00d8, Denmark"],"affiliations":[{"raw_affiliation_string":"Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, 2800 Kongens Lyngby, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I96673099"]},{"raw_affiliation_string":"Unseen Biometrics ApS, Fruebjergvej 3, 2100\u00a0K\u00f8benhavn \u00d8, Denmark","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084952464","display_name":"Mattia G. Gollub","orcid":"https://orcid.org/0000-0001-9588-3130"},"institutions":[{"id":"https://openalex.org/I12708293","display_name":"SIB Swiss Institute of Bioinformatics","ror":"https://ror.org/002n09z45","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I12708293"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Mattia G Gollub","raw_affiliation_strings":["Department of Biosystems Science and Engineering and SIB Swiss Institute of Bioinformatics, ETH Z\u00fcrich, Basel\u00a04058, Switzerland"],"affiliations":[{"raw_affiliation_string":"Department of Biosystems Science and Engineering and SIB Swiss Institute of Bioinformatics, ETH Z\u00fcrich, Basel\u00a04058, Switzerland","institution_ids":["https://openalex.org/I12708293","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042337184","display_name":"Dana Mozaffari","orcid":null},"institutions":[{"id":"https://openalex.org/I12708293","display_name":"SIB Swiss Institute of Bioinformatics","ror":"https://ror.org/002n09z45","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I12708293"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Dana Mozaffari","raw_affiliation_strings":["Department of Biosystems Science and Engineering and SIB Swiss Institute of Bioinformatics, ETH Z\u00fcrich, Basel\u00a04058, Switzerland","Institute of Chemical Sciences and Engineering, EPFL, Lausanne\u00a01015, Switzerland"],"affiliations":[{"raw_affiliation_string":"Department of Biosystems Science and Engineering and SIB Swiss Institute of Bioinformatics, ETH Z\u00fcrich, Basel\u00a04058, Switzerland","institution_ids":["https://openalex.org/I12708293","https://openalex.org/I35440088"]},{"raw_affiliation_string":"Institute of Chemical Sciences and Engineering, EPFL, Lausanne\u00a01015, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067028539","display_name":"Kevin M. Shebek","orcid":null},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin M Shebek","raw_affiliation_strings":["Department of Chemical and Biological Engineering, Chemistry of Life Processes Institute, and Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA"],"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biological Engineering, Chemistry of Life Processes Institute, and Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062382712","display_name":"Avi I. Flamholz","orcid":"https://orcid.org/0000-0002-9278-5479"},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Avi\u00a0I Flamholz","raw_affiliation_strings":["Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA"],"affiliations":[{"raw_affiliation_string":"Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA","institution_ids":["https://openalex.org/I122411786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024451873","display_name":"Ron Milo","orcid":"https://orcid.org/0000-0003-1641-2299"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Ron Milo","raw_affiliation_strings":["Department of Plant and Environmental Sciences, Weizmann Institute of Science, Herzl 234, Rehovot 7610001, Israel"],"affiliations":[{"raw_affiliation_string":"Department of Plant and Environmental Sciences, Weizmann Institute of Science, Herzl 234, Rehovot 7610001, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021074279","display_name":"\u0395lad Noor","orcid":"https://orcid.org/0000-0001-8776-4799"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Elad Noor","raw_affiliation_strings":["Department of Plant and Environmental Sciences, Weizmann Institute of Science, Herzl 234, Rehovot 7610001, Israel"],"affiliations":[{"raw_affiliation_string":"Department of Plant and Environmental Sciences, Weizmann Institute of Science, Herzl 234, Rehovot 7610001, Israel","institution_ids":["https://openalex.org/I53964585"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5021074279"],"corresponding_institution_ids":["https://openalex.org/I53964585"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":10.0023,"has_fulltext":false,"cited_by_count":197,"citation_normalized_percentile":{"value":0.99013229,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"50","issue":"D1","first_page":"D603","last_page":"D609"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10791","display_name":"Advanced Control Systems Optimization","score":0.9943000078201294,"subfield":{"id":"https://openalex.org/subfields/2207","display_name":"Control and Systems Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11053","display_name":"Process Optimization and Integration","score":0.9939000010490417,"subfield":{"id":"https://openalex.org/subfields/2207","display_name":"Control and Systems Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8431264162063599},{"id":"https://openalex.org/keywords/constant","display_name":"Constant (computer programming)","score":0.6431082487106323},{"id":"https://openalex.org/keywords/estimation","display_name":"Estimation","score":0.5629795789718628},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.39805564284324646},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.1538817584514618}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8431264162063599},{"id":"https://openalex.org/C2777027219","wikidata":"https://www.wikidata.org/wiki/Q1284190","display_name":"Constant (computer programming)","level":2,"score":0.6431082487106323},{"id":"https://openalex.org/C96250715","wikidata":"https://www.wikidata.org/wiki/Q965330","display_name":"Estimation","level":2,"score":0.5629795789718628},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.39805564284324646},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1538817584514618},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C187736073","wikidata":"https://www.wikidata.org/wiki/Q2920921","display_name":"Management","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007477","descriptor_name":"Ions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007477","descriptor_name":"Ions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007477","descriptor_name":"Ions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1093/nar/gkab1106","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab1106","pdf_url":"https://academic.oup.com/nar/article-pdf/50/D1/D603/42057662/gkab1106.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:34850162","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34850162","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:authors.library.caltech.edu:112306","is_oa":true,"landing_page_url":"https://authors.library.caltech.edu/112306/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402161","display_name":"CaltechAUTHORS (California Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I122411786","host_organization_name":"California Institute of Technology","host_organization_lineage":["https://openalex.org/I122411786"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:osti.gov:1833443","is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1833443","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:osti.gov:1904393","is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1904393","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8728285","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8728285","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:publications/a1269a67-1dd5-4188-b716-ffdb5ea31212","is_oa":true,"landing_page_url":"https://orbit.dtu.dk/en/publications/a1269a67-1dd5-4188-b716-ffdb5ea31212","pdf_url":null,"source":{"id":"https://openalex.org/S4306400705","display_name":"Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I96673099","host_organization_name":"Technical University of Denmark","host_organization_lineage":["https://openalex.org/I96673099"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Beber , M E , Gollub , M G , Mozaffari , D , Shebek , K M , Flamholz , A I , Milo , R & Noor , E 2022 , ' eQuilibrator 3.0: a database solution for thermodynamic constant estimation ' , Nucleic Acids Research , vol. 50 , no. D1 , pp. D603\u2013D609 . https://doi.org/10.1093/nar/gkab1106","raw_type":"article"},{"id":"pmh:oai:www.research-collection.ethz.ch:20.500.11850/530926","is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.11850/530926","pdf_url":null,"source":{"id":"https://openalex.org/S4306402302","display_name":"Repository for Publications and Research Data (ETH Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I35440088","host_organization_name":"ETH Zurich","host_organization_lineage":["https://openalex.org/I35440088"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Research, 50 (D1)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"doi:10.3929/ethz-b-000530926","is_oa":true,"landing_page_url":"https://doi.org/10.3929/ethz-b-000530926","pdf_url":null,"source":{"id":"https://openalex.org/S7407051236","display_name":"ETH Z\u00fcrich Research Collection","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1093/nar/gkab1106","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkab1106","pdf_url":"https://academic.oup.com/nar/article-pdf/50/D1/D603/42057662/gkab1106.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1172106845","display_name":null,"funder_award_id":"177164","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G6467642042","display_name":null,"funder_award_id":"DE-SC0018249","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G8162574379","display_name":null,"funder_award_id":"686070","funder_id":"https://openalex.org/F4320335254","funder_display_name":"Horizon 2020"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320335254","display_name":"Horizon 2020","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3216494066.pdf","grobid_xml":"https://content.openalex.org/works/W3216494066.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W1588504519","https://openalex.org/W1934481644","https://openalex.org/W1935434993","https://openalex.org/W1978078364","https://openalex.org/W1997733142","https://openalex.org/W1997996256","https://openalex.org/W2011354860","https://openalex.org/W2022374283","https://openalex.org/W2035612098","https://openalex.org/W2042067428","https://openalex.org/W2048465561","https://openalex.org/W2056139823","https://openalex.org/W2088659094","https://openalex.org/W2100084634","https://openalex.org/W2107409961","https://openalex.org/W2109785748","https://openalex.org/W2114326383","https://openalex.org/W2114775507","https://openalex.org/W2116802060","https://openalex.org/W2116976883","https://openalex.org/W2117306286","https://openalex.org/W2123060905","https://openalex.org/W2123875295","https://openalex.org/W2125122419","https://openalex.org/W2154126596","https://openalex.org/W2170427655","https://openalex.org/W2202347610","https://openalex.org/W2312280072","https://openalex.org/W2466795701","https://openalex.org/W2555587815","https://openalex.org/W2788103142","https://openalex.org/W2810239425","https://openalex.org/W2833943491","https://openalex.org/W2889925337","https://openalex.org/W2902733144","https://openalex.org/W2915782277","https://openalex.org/W2944003288","https://openalex.org/W2949078105","https://openalex.org/W2949418748","https://openalex.org/W2951700574","https://openalex.org/W2973960665","https://openalex.org/W3010629926","https://openalex.org/W3037347004","https://openalex.org/W3081478800","https://openalex.org/W3090689814","https://openalex.org/W3095049046","https://openalex.org/W3119760375","https://openalex.org/W3135238077","https://openalex.org/W3138245369","https://openalex.org/W4247462530","https://openalex.org/W4301267015","https://openalex.org/W4301602820","https://openalex.org/W6749314103","https://openalex.org/W6783796321"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W2013243191","https://openalex.org/W1971568933"],"abstract_inverted_index":{"eQuilibrator":[0,78,152],"(equilibrator.weizmann.ac.il)":[1],"is":[2],"a":[3,16,40,73,86],"database":[4,66],"of":[5,72,118,151],"biochemical":[6],"equilibrium":[7],"constants":[8],"and":[9,37,100,103,129,147],"Gibbs":[10],"free":[11],"energies,":[12],"originally":[13],"designed":[14],"as":[15,67,69,85],"web-based":[17],"interface.":[18],"While":[19],"the":[20,53,61,65,70,91,110,115,119,127,131,149],"website":[21],"now":[22],"counts":[23],"around":[24],"1,000":[25],"distinct":[26],"monthly":[27],"users,":[28],"its":[29],"design":[30],"could":[31],"not":[32],"accommodate":[33],"larger":[34,88],"compound":[35,89],"databases":[36],"it":[38],"lacked":[39],"scalable":[41],"Application":[42],"Programming":[43],"Interface":[44],"(API)":[45],"for":[46,105,123],"integration":[47,150],"into":[48,153],"other":[49,154],"tools":[50],"developed":[51],"by":[52],"systems":[54],"biology":[55],"community.":[56],"Here,":[57],"we":[58,125],"report":[59],"on":[60],"recent":[62],"updates":[63],"to":[64,77,93],"well":[68],"addition":[71],"new":[74,82,111],"Python-based":[75],"interface":[76,112],"that":[79,138],"adds":[80],"many":[81],"features":[83],"such":[84],"100-fold":[87],"database,":[90],"ability":[92],"add":[94],"novel":[95],"compounds,":[96],"improvements":[97,140],"in":[98,133],"speed":[99],"memory":[101],"use,":[102],"correction":[104],"Mg2+":[106],"ion":[107],"concentrations.":[108],"Moreover,":[109],"can":[113],"compute":[114],"covariance":[116],"matrix":[117],"uncertainty":[120],"between":[121],"estimates,":[122],"which":[124],"show":[126],"advantages":[128],"describe":[130],"application":[132],"metabolic":[134],"modelling.":[135],"We":[136],"foresee":[137],"these":[139],"will":[141],"make":[142],"thermodynamic":[143],"modelling":[144],"more":[145],"accessible":[146],"facilitate":[148],"software":[155],"platforms.":[156]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":59},{"year":2024,"cited_by_count":55},{"year":2023,"cited_by_count":48},{"year":2022,"cited_by_count":18},{"year":2021,"cited_by_count":2}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}