{"id":"https://openalex.org/W3098804002","doi":"https://doi.org/10.1093/nar/gkaa1033","title":"OncoVar: an integrated database and analysis platform for oncogenic driver variants in cancers","display_name":"OncoVar: an integrated database and analysis platform for oncogenic driver variants in cancers","publication_year":2020,"publication_date":"2020-10-19","ids":{"openalex":"https://openalex.org/W3098804002","doi":"https://doi.org/10.1093/nar/gkaa1033","mag":"3098804002","pmid":"https://pubmed.ncbi.nlm.nih.gov/33179738"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkaa1033","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkaa1033","pdf_url":"https://academic.oup.com/nar/article-pdf/49/D1/D1289/35363926/gkaa1033.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/49/D1/D1289/35363926/gkaa1033.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060759543","display_name":"Tao Wang","orcid":"https://orcid.org/0009-0004-8060-4978"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210098099","display_name":"Chinese Nutrition Society","ror":"https://ror.org/00yg6a139","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210098099"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tao Wang","raw_affiliation_strings":["Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China","Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan 410083, China"],"affiliations":[{"raw_affiliation_string":"Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I4210098099","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan 410083, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104113067","display_name":"Shasha Ruan","orcid":null},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4210140357","display_name":"Renmin Hospital of Wuhan University","ror":"https://ror.org/03ekhbz91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210140357"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shasha Ruan","raw_affiliation_strings":["Department of Clinical Oncology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430072, China"],"affiliations":[{"raw_affiliation_string":"Department of Clinical Oncology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430072, China","institution_ids":["https://openalex.org/I37461747","https://openalex.org/I4210140357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090874503","display_name":"Xiaolu Zhao","orcid":"https://orcid.org/0000-0003-1535-3880"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaolu Zhao","raw_affiliation_strings":["Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China"],"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210141942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031545203","display_name":"Xiaohui Shi","orcid":"https://orcid.org/0000-0002-4025-1715"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210098099","display_name":"Chinese Nutrition Society","ror":"https://ror.org/00yg6a139","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210098099"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaohui Shi","raw_affiliation_strings":["Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I4210098099","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068012395","display_name":"Huajing Teng","orcid":"https://orcid.org/0000-0001-9952-3618"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210098099","display_name":"Chinese Nutrition Society","ror":"https://ror.org/00yg6a139","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210098099"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huajing Teng","raw_affiliation_strings":["Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I4210098099","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011052182","display_name":"Jianing Zhong","orcid":"https://orcid.org/0000-0002-2781-3437"},"institutions":[{"id":"https://openalex.org/I4210113195","display_name":"Gannan Medical University","ror":"https://ror.org/01tjgw469","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianing Zhong","raw_affiliation_strings":["Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou 341000, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou 341000, China","institution_ids":["https://openalex.org/I4210113195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047319857","display_name":"Mingcong You","orcid":null},"institutions":[{"id":"https://openalex.org/I98301712","display_name":"Baidu (China)","ror":"https://ror.org/03vs3wt56","country_code":"CN","type":"company","lineage":["https://openalex.org/I98301712"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingcong You","raw_affiliation_strings":["Baiyining Medicine, Beijing 102200, China"],"affiliations":[{"raw_affiliation_string":"Baiyining Medicine, Beijing 102200, China","institution_ids":["https://openalex.org/I98301712"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049361243","display_name":"Kun Xia","orcid":"https://orcid.org/0000-0001-8090-6002"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210097554","display_name":"Center for Excellence in Brain Science and Intelligence Technology","ror":"https://ror.org/00vpwhm04","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210097554"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Kun Xia","raw_affiliation_strings":["CAS Center for Excellence in Brain Science and Intelligences Technology (CEBSIT), Shanghai 200031, China","Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan 410083, China","School of Basic Medical Science, Central South University, Changsha, Hunan 410078, China"],"affiliations":[{"raw_affiliation_string":"CAS Center for Excellence in Brain Science and Intelligences Technology (CEBSIT), Shanghai 200031, China","institution_ids":["https://openalex.org/I4210097554"]},{"raw_affiliation_string":"Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan 410083, China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"School of Basic Medical Science, Central South University, Changsha, Hunan 410078, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013751352","display_name":"Zhong Sheng Sun","orcid":"https://orcid.org/0000-0002-7640-5026"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210098099","display_name":"Chinese Nutrition Society","ror":"https://ror.org/00yg6a139","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210098099"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhongsheng Sun","raw_affiliation_strings":["Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China","CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing 100049, China","State Key Laboratory of Integrated Management of Pest Insects and Rodents, Chinese Academy of Sciences, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I4210098099","https://openalex.org/I19820366"]},{"raw_affiliation_string":"CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"State Key Laboratory of Integrated Management of Pest Insects and Rodents, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046363705","display_name":"Fengbiao Mao","orcid":"https://orcid.org/0000-0003-0852-4266"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Fengbiao Mao","raw_affiliation_strings":["Center of Basic Medical Research, Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing 100191, China"],"affiliations":[{"raw_affiliation_string":"Center of Basic Medical Research, Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210141942"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5013751352","https://openalex.org/A5046363705","https://openalex.org/A5049361243"],"corresponding_institution_ids":["https://openalex.org/I139660479","https://openalex.org/I19820366","https://openalex.org/I20231570","https://openalex.org/I4210097554","https://openalex.org/I4210098099","https://openalex.org/I4210141942","https://openalex.org/I4210165038"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":5.5084,"has_fulltext":true,"cited_by_count":109,"citation_normalized_percentile":{"value":0.97537015,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"49","issue":"D1","first_page":"D1289","last_page":"D1301"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9815000295639038,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.913040041923523},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4651437997817993},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.424580454826355},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.3974534571170807},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3278975784778595},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.08551239967346191}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.913040041923523},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4651437997817993},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.424580454826355},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.3974534571170807},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3278975784778595},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.08551239967346191}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009857","descriptor_name":"Oncogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009857","descriptor_name":"Oncogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009857","descriptor_name":"Oncogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009857","descriptor_name":"Oncogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059472","descriptor_name":"Exome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059472","descriptor_name":"Exome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059472","descriptor_name":"Exome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059472","descriptor_name":"Exome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/nar/gkaa1033","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkaa1033","pdf_url":"https://academic.oup.com/nar/article-pdf/49/D1/D1289/35363926/gkaa1033.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:33179738","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33179738","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7778899","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7778899","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkaa1033","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkaa1033","pdf_url":"https://academic.oup.com/nar/article-pdf/49/D1/D1289/35363926/gkaa1033.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2223675843","display_name":null,"funder_award_id":"31872237","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2564019113","display_name":null,"funder_award_id":"2016YFC0900400","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3708434900","display_name":null,"funder_award_id":"81730036","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4754858258","display_name":null,"funder_award_id":"81525007","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994494637","display_name":null,"funder_award_id":"and 81","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6416960803","display_name":null,"funder_award_id":"2012AA02A210","funder_id":"https://openalex.org/F4320335773","funder_display_name":"National High-tech Research and Development Program"},{"id":"https://openalex.org/G6533370096","display_name":null,"funder_award_id":"817300","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335773","display_name":"National High-tech Research and Development Program","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3098804002.pdf","grobid_xml":"https://content.openalex.org/works/W3098804002.grobid-xml"},"referenced_works_count":91,"referenced_works":["https://openalex.org/W1829137581","https://openalex.org/W1976579581","https://openalex.org/W1980740976","https://openalex.org/W1984068087","https://openalex.org/W1984675437","https://openalex.org/W1996442028","https://openalex.org/W2009720434","https://openalex.org/W2011582941","https://openalex.org/W2011941471","https://openalex.org/W2024405748","https://openalex.org/W2024890690","https://openalex.org/W2035618305","https://openalex.org/W2038473742","https://openalex.org/W2050212230","https://openalex.org/W2059145105","https://openalex.org/W2061596350","https://openalex.org/W2072467429","https://openalex.org/W2082426444","https://openalex.org/W2094122486","https://openalex.org/W2100867326","https://openalex.org/W2106306904","https://openalex.org/W2111326065","https://openalex.org/W2114029728","https://openalex.org/W2114031931","https://openalex.org/W2116798163","https://openalex.org/W2121443461","https://openalex.org/W2124789022","https://openalex.org/W2129952088","https://openalex.org/W2129973040","https://openalex.org/W2139227366","https://openalex.org/W2144940507","https://openalex.org/W2145187337","https://openalex.org/W2145191876","https://openalex.org/W2148105023","https://openalex.org/W2152176732","https://openalex.org/W2155845523","https://openalex.org/W2158529347","https://openalex.org/W2159987716","https://openalex.org/W2160995259","https://openalex.org/W2161162779","https://openalex.org/W2166771322","https://openalex.org/W2192915867","https://openalex.org/W2204695746","https://openalex.org/W2225726427","https://openalex.org/W2255206707","https://openalex.org/W2257370818","https://openalex.org/W2345713578","https://openalex.org/W2436745791","https://openalex.org/W2442835468","https://openalex.org/W2521967673","https://openalex.org/W2535426958","https://openalex.org/W2543582635","https://openalex.org/W2557187647","https://openalex.org/W2558715006","https://openalex.org/W2614443510","https://openalex.org/W2764327284","https://openalex.org/W2766367874","https://openalex.org/W2767157762","https://openalex.org/W2769834144","https://openalex.org/W2776882820","https://openalex.org/W2784142616","https://openalex.org/W2790516087","https://openalex.org/W2794804602","https://openalex.org/W2796153225","https://openalex.org/W2796153844","https://openalex.org/W2796408191","https://openalex.org/W2883631445","https://openalex.org/W2884736612","https://openalex.org/W2893367264","https://openalex.org/W2896872272","https://openalex.org/W2898789672","https://openalex.org/W2910305771","https://openalex.org/W2915168078","https://openalex.org/W2949181286","https://openalex.org/W2949492942","https://openalex.org/W2950753203","https://openalex.org/W2951276412","https://openalex.org/W2971254602","https://openalex.org/W2985613549","https://openalex.org/W3000249748","https://openalex.org/W3004392981","https://openalex.org/W3004859565","https://openalex.org/W3006500278","https://openalex.org/W3008303614","https://openalex.org/W3029661147","https://openalex.org/W3047825284","https://openalex.org/W3095895133","https://openalex.org/W6679257246","https://openalex.org/W6738337739","https://openalex.org/W6758451182","https://openalex.org/W6769900914"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W2013243191","https://openalex.org/W1971568933"],"abstract_inverted_index":{"The":[0,81],"prevalence":[1],"of":[2,12,25,103,124,135,166],"neutral":[3],"mutations":[4,15,27,51,177],"in":[5,80,93,156,194],"cancer":[6,29,59,78,91,158,167,171,186,195],"cell":[7],"population":[8],"impedes":[9],"the":[10,22,115,164,189],"distinguishing":[11],"cancer-causing":[13],"driver":[14,46,50,53,60,63,120,126,149,151],"from":[16,76,89],"passenger":[17],"mutations.":[18],"To":[19],"systematically":[20],"prioritize":[21],"oncogenic":[23],"ability":[24],"somatic":[26,148],"and":[28,43,52,65,86,108,119,132,146,153,173,188],"genes,":[30],"we":[31],"constructed":[32],"a":[33,140],"useful":[34],"platform,":[35],"OncoVar":[36,99,138],"(https://oncovar.org/),":[37],"which":[38],"employed":[39],"published":[40],"bioinformatics":[41],"algorithms":[42],"incorporated":[44],"known":[45],"events":[47],"to":[48,110,113,175],"identify":[49],"genes.":[54],"We":[55],"identified":[56],"20":[57],"162":[58],"mutations,":[61,150],"814":[62],"genes":[64,152,179],"2360":[66],"pathogenic":[67,154],"pathways":[68,155],"with":[69],"high-confidence":[70],"by":[71],"reanalyzing":[72],"10":[73],"769":[74],"exomes":[75],"33":[77],"types":[79,92],"Cancer":[82,95],"Genome":[83,96],"Atlas":[84],"(TCGA)":[85],"1942":[87],"genomes":[88],"18":[90],"International":[94],"Consortium":[97],"(ICGC).":[98],"provides":[100,128,139],"four":[101],"points":[102],"view,":[104],"'Mutation',":[105],"'Gene',":[106],"'Pathway'":[107],"'Cancer',":[109],"help":[111],"researchers":[112,187],"visualize":[114],"relationships":[116],"between":[117],"cancers":[118],"variants.":[121],"Importantly,":[122],"identification":[123,165],"actionable":[125],"alterations":[127],"promising":[129],"druggable":[130],"targets":[131],"repurposing":[133],"opportunities":[134],"combinational":[136],"therapies.":[137],"user-friendly":[141],"interface":[142],"for":[143,180],"browsing,":[144],"searching":[145],"downloading":[147],"various":[157],"types.":[159],"This":[160],"platform":[161],"will":[162],"facilitate":[163],"drivers":[168],"across":[169],"individual":[170],"cohorts":[172],"helps":[174],"rank":[176],"or":[178],"better":[181],"decision-making":[182],"among":[183],"clinical":[184],"oncologists,":[185],"broad":[190],"scientific":[191],"community":[192],"interested":[193],"precision":[196],"medicine.":[197]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":30},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":3}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}