{"id":"https://openalex.org/W3099496190","doi":"https://doi.org/10.1093/nar/gkaa1004","title":"The Transporter Classification Database (TCDB): 2021 update","display_name":"The Transporter Classification Database (TCDB): 2021 update","publication_year":2020,"publication_date":"2020-10-16","ids":{"openalex":"https://openalex.org/W3099496190","doi":"https://doi.org/10.1093/nar/gkaa1004","mag":"3099496190","pmid":"https://pubmed.ncbi.nlm.nih.gov/33170213"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkaa1004","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkaa1004","pdf_url":"https://academic.oup.com/nar/article-pdf/49/D1/D461/35363716/gkaa1004.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/49/D1/D461/35363716/gkaa1004.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063618841","display_name":"Milton H. Saier","orcid":"https://orcid.org/0000-0001-5530-0017"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Milton H Saier","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":"https://orcid.org/0000-0001-5530-0017","affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030554386","display_name":"Vamsee Reddy","orcid":null},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vamsee S Reddy","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057232313","display_name":"Gabriel Moreno\u2010Hagelsieb","orcid":"https://orcid.org/0000-0002-2457-4450"},"institutions":[{"id":"https://openalex.org/I75381157","display_name":"Wilfrid Laurier University","ror":"https://ror.org/00fn7gb05","country_code":"CA","type":"education","lineage":["https://openalex.org/I75381157"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Gabriel Moreno-Hagelsieb","raw_affiliation_strings":["Department of Biology, Wilfrid Laurier University, Waterloo, Ontario N2L 3C5, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Wilfrid Laurier University, Waterloo, Ontario N2L 3C5, Canada","institution_ids":["https://openalex.org/I75381157"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003678380","display_name":"Kevin J. Hendargo","orcid":null},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin J Hendargo","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100444202","display_name":"Yichi Zhang","orcid":"https://orcid.org/0000-0003-3932-3088"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yichi Zhang","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016618322","display_name":"Vasu Iddamsetty","orcid":null},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vasu Iddamsetty","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027567325","display_name":"Katie Jing Kay Lam","orcid":"https://orcid.org/0000-0001-6455-3497"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katie\u00a0Jing\u00a0Kay Lam","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054644757","display_name":"Nuo Tian","orcid":"https://orcid.org/0009-0001-8048-7474"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nuo Tian","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078180294","display_name":"Steven Russum","orcid":null},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Russum","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101411102","display_name":"Jia\u2010Ning Wang","orcid":"https://orcid.org/0000-0003-0135-8832"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianing Wang","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011434478","display_name":"Arturo Medrano-Soto","orcid":"https://orcid.org/0000-0002-6095-3829"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arturo Medrano-Soto","raw_affiliation_strings":["Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA"],"raw_orcid":"https://orcid.org/0000-0002-6095-3829","affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5011434478","https://openalex.org/A5063618841"],"corresponding_institution_ids":["https://openalex.org/I36258959"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":15.1705,"has_fulltext":true,"cited_by_count":468,"citation_normalized_percentile":{"value":0.99500011,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"49","issue":"D1","first_page":"D461","last_page":"D467"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6857141852378845},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5292016267776489},{"id":"https://openalex.org/keywords/transporter","display_name":"Transporter","score":0.5037853121757507},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.49826622009277344},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.49771884083747864},{"id":"https://openalex.org/keywords/protein-family","display_name":"Protein family","score":0.4191412329673767},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.320346474647522},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2168891429901123},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.15678361058235168},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.09157627820968628}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6857141852378845},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5292016267776489},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.5037853121757507},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.49826622009277344},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.49771884083747864},{"id":"https://openalex.org/C171897839","wikidata":"https://www.wikidata.org/wiki/Q417841","display_name":"Protein family","level":3,"score":0.4191412329673767},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.320346474647522},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2168891429901123},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.15678361058235168},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09157627820968628},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072417","descriptor_name":"Protein Domains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072417","descriptor_name":"Protein Domains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072417","descriptor_name":"Protein Domains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/nar/gkaa1004","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkaa1004","pdf_url":"https://academic.oup.com/nar/article-pdf/49/D1/D461/35363716/gkaa1004.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:33170213","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33170213","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7778945","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7778945","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"doi:10.25504/fairsharing.p3bzqb","is_oa":true,"landing_page_url":"https://doi.org/10.25504/fairsharing.p3bzqb","pdf_url":null,"source":{"id":"https://openalex.org/S7407053452","display_name":"FAIRsharing.org","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"dataset"}],"best_oa_location":{"id":"doi:10.1093/nar/gkaa1004","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkaa1004","pdf_url":"https://academic.oup.com/nar/article-pdf/49/D1/D461/35363716/gkaa1004.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Partnerships for the goals","score":0.4699999988079071,"id":"https://metadata.un.org/sdg/17"}],"awards":[{"id":"https://openalex.org/G4448319866","display_name":null,"funder_award_id":"GM077402","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3099496190.pdf","grobid_xml":"https://content.openalex.org/works/W3099496190.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W20042724","https://openalex.org/W127318549","https://openalex.org/W1104092994","https://openalex.org/W1606415723","https://openalex.org/W1713112461","https://openalex.org/W1836504464","https://openalex.org/W1935434993","https://openalex.org/W1985584408","https://openalex.org/W1992928993","https://openalex.org/W1993460406","https://openalex.org/W2040751953","https://openalex.org/W2040836575","https://openalex.org/W2071416115","https://openalex.org/W2080963155","https://openalex.org/W2095392992","https://openalex.org/W2105300849","https://openalex.org/W2106192857","https://openalex.org/W2114347076","https://openalex.org/W2132926880","https://openalex.org/W2138122982","https://openalex.org/W2144944670","https://openalex.org/W2151678089","https://openalex.org/W2158714788","https://openalex.org/W2168929754","https://openalex.org/W2199967493","https://openalex.org/W2268222194","https://openalex.org/W2292734588","https://openalex.org/W2313691908","https://openalex.org/W2315521535","https://openalex.org/W2408283677","https://openalex.org/W2416257855","https://openalex.org/W2557840611","https://openalex.org/W2570966356","https://openalex.org/W2578958622","https://openalex.org/W2597745274","https://openalex.org/W2598667758","https://openalex.org/W2766737008","https://openalex.org/W2768802022","https://openalex.org/W2775775382","https://openalex.org/W2786787899","https://openalex.org/W2790990272","https://openalex.org/W2898402099","https://openalex.org/W2902458922","https://openalex.org/W2941031266","https://openalex.org/W2952886161","https://openalex.org/W2972361934","https://openalex.org/W2991012415","https://openalex.org/W3011677547","https://openalex.org/W3017078513","https://openalex.org/W3024531541","https://openalex.org/W3099496190","https://openalex.org/W4214952473","https://openalex.org/W4242186257","https://openalex.org/W6605205647","https://openalex.org/W6713851139"],"related_works":["https://openalex.org/W2484314540","https://openalex.org/W3010947738","https://openalex.org/W2898732673","https://openalex.org/W2093266223","https://openalex.org/W2410053581","https://openalex.org/W2383658677","https://openalex.org/W2003932708","https://openalex.org/W3123203398","https://openalex.org/W1967424056","https://openalex.org/W1971962175"],"abstract_inverted_index":{"The":[0],"Transporter":[1],"Classification":[2],"Database":[3],"(TCDB;":[4],"tcdb.org)":[5],"is":[6,29,88],"a":[7,117,130],"freely":[8],"accessible":[9],"reference":[10,71],"resource,":[11],"which":[12,78],"provides":[13],"functional,":[14],"structural,":[15],"mechanistic,":[16],"medical":[17],"and":[18,43,47,111,146,159,178,184,194],"biotechnological":[19],"information":[20],"about":[21],"transporters":[22],"from":[23],"organisms":[24],"of":[25,41,53,77,82,91,99,107,116,122,126,133,139,153,161,166,169,176,181,188],"all":[26],"types.":[27],"TCDB":[28],"the":[30,38,95,100,108,137,162,186],"only":[31],"transport":[32,62,170],"protein":[33],"classification":[34],"database":[35,101,109],"adopted":[36],"by":[37],"International":[39],"Union":[40],"Biochemistry":[42],"Molecular":[44],"Biology":[45],"(IUBMB)":[46],"now":[48],"(October":[49],"1,":[50],"2020)":[51],"consists":[52],"20":[54],"653":[55],"proteins":[56],"classified":[57],"in":[58,102],"15":[59],"528":[60],"non-redundant":[61],"systems":[63,171],"with":[64],"1567":[65],"tabulated":[66],"3D":[67],"structures,":[68],"18":[69],"336":[70],"citations":[72],"describing":[73],"1536":[74],"transporter":[75,134],"families,":[76,150],"26%":[79],"are":[80],"members":[81,141],"82":[83],"recognized":[84],"superfamilies.":[85],"Overall,":[86],"this":[87],"an":[89],"increase":[90],"over":[92],"50%":[93],"since":[94],"last":[96],"published":[97],"update":[98,106],"2016.":[103],"This":[104],"comprehensive":[105],"contents":[110],"features":[112],"include":[113],"(i)":[114],"adoption":[115],"chemical":[118],"ontology":[119],"for":[120,136],"substrates":[121],"transporters,":[123],"(ii)":[124],"inclusion":[125,187],"new":[127,140,167],"superfamilies,":[128],"(iii)":[129],"domain-based":[131],"characterization":[132],"families":[135],"identification":[138],"as":[142,144],"well":[143],"functional":[145],"evolutionary":[147],"relationships":[148],"between":[149],"(iv)":[151],"development":[152],"novel":[154,174],"software":[155],"to":[156],"facilitate":[157],"curation":[158],"use":[160],"database,":[163],"(v)":[164],"addition":[165],"subclasses":[168],"including":[172],"11":[173],"types":[175,180],"channels":[177],"3":[179],"group":[182],"translocators":[183],"(vi)":[185],"many":[189],"man-made":[190],"(artificial)":[191],"transmembrane":[192],"pores/channels":[193],"carriers.":[195]},"counts_by_year":[{"year":2026,"cited_by_count":32},{"year":2025,"cited_by_count":122},{"year":2024,"cited_by_count":132},{"year":2023,"cited_by_count":87},{"year":2022,"cited_by_count":68},{"year":2021,"cited_by_count":26},{"year":2020,"cited_by_count":1}],"updated_date":"2026-05-09T13:55:54.758798","created_date":"2020-11-23T00:00:00"}