{"id":"https://openalex.org/W2917197653","doi":"https://doi.org/10.1093/jamia/ocy169","title":"Patient free text reporting of symptomatic adverse events in cancer clinical research using the National Cancer Institute\u2019s Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE)","display_name":"Patient free text reporting of symptomatic adverse events in cancer clinical research using the National Cancer Institute\u2019s Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE)","publication_year":2018,"publication_date":"2018-11-26","ids":{"openalex":"https://openalex.org/W2917197653","doi":"https://doi.org/10.1093/jamia/ocy169","mag":"2917197653","pmid":"https://pubmed.ncbi.nlm.nih.gov/30840079"},"language":"en","primary_location":{"id":"doi:10.1093/jamia/ocy169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocy169","pdf_url":"https://academic.oup.com/jamia/article-pdf/26/4/276/34151401/ocy169.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jamia/article-pdf/26/4/276/34151401/ocy169.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021279490","display_name":"Arlene E. Chung","orcid":"https://orcid.org/0000-0002-4821-0256"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arlene E Chung","raw_affiliation_strings":["Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA","Program on Health and Clinical Informatics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Program on Health and Clinical Informatics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037621002","display_name":"Kimberly A. Shoenbill","orcid":"https://orcid.org/0000-0002-2693-638X"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly Shoenbill","raw_affiliation_strings":["Department of Family Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","Program on Health and Clinical Informatics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Family Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Program on Health and Clinical Informatics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016587367","display_name":"Sandra A. Mitchell","orcid":"https://orcid.org/0000-0002-4153-9972"},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandra A Mitchell","raw_affiliation_strings":["National Cancer Institute, Rockville, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute, Rockville, Maryland, USA","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090009905","display_name":"Amylou C. Dueck","orcid":"https://orcid.org/0000-0002-9912-1085"},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amylou C Dueck","raw_affiliation_strings":["Alliance Statistics and Data Center, Mayo Clinic, Scottsdale, Arizona, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alliance Statistics and Data Center, Mayo Clinic, Scottsdale, Arizona, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088893766","display_name":"Deborah Schrag","orcid":"https://orcid.org/0000-0002-4334-5717"},"institutions":[{"id":"https://openalex.org/I4210134579","display_name":"Dana-Farber/Harvard Cancer Center","ror":"https://ror.org/03pvyf116","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah Schrag","raw_affiliation_strings":["Division of Population Sciences, Department of Medical Oncology, Dana-Farber/Harvard Cancer Center, Brookline, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Population Sciences, Department of Medical Oncology, Dana-Farber/Harvard Cancer Center, Brookline, Massachusetts, USA","institution_ids":["https://openalex.org/I4210134579"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005691073","display_name":"Deborah Watkins Bruner","orcid":"https://orcid.org/0000-0002-5770-9948"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah W Bruner","raw_affiliation_strings":["Nell Hodgson Woodruff School of Nursing, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nell Hodgson Woodruff School of Nursing, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037416583","display_name":"Lori M. Minasian","orcid":null},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lori M Minasian","raw_affiliation_strings":["National Cancer Institute, Rockville, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute, Rockville, Maryland, USA","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048639435","display_name":"Diane St. Germain","orcid":"https://orcid.org/0000-0003-0399-5579"},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diane St. Germain","raw_affiliation_strings":["National Cancer Institute, Rockville, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute, Rockville, Maryland, USA","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110461913","display_name":"Ann M. O\u2019Mara","orcid":null},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ann M O\u2019Mara","raw_affiliation_strings":["National Cancer Institute, Rockville, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute, Rockville, Maryland, USA","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057298249","display_name":"Paul Baumgartner","orcid":"https://orcid.org/0000-0002-1188-9648"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul Baumgartner","raw_affiliation_strings":["Semantic Bits, LLC, Herndon, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Semantic Bits, LLC, Herndon, Virginia, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069643040","display_name":"Lauren J. Rogak","orcid":"https://orcid.org/0000-0002-6415-1575"},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lauren J Rogak","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079817843","display_name":"Amy P. Abernethy","orcid":"https://orcid.org/0000-0001-6930-8722"},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4390039326","display_name":"Duke Cancer Institute","ror":"https://ror.org/04vt65461","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876","https://openalex.org/I4390039326"]},{"id":"https://openalex.org/I4210153546","display_name":"Flatiron Health (United States)","ror":"https://ror.org/0508h6p74","country_code":"US","type":"company","lineage":["https://openalex.org/I4210153546"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy P Abernethy","raw_affiliation_strings":["Department of Medicine, Duke Cancer Institute, Durham, North Carolina, USA","Flatiron Health, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Duke Cancer Institute, Durham, North Carolina, USA","institution_ids":["https://openalex.org/I4210126298","https://openalex.org/I4390039326"]},{"raw_affiliation_string":"Flatiron Health, New York, New York, USA","institution_ids":["https://openalex.org/I4210153546"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057398323","display_name":"Ashley C Griffin","orcid":"https://orcid.org/0000-0002-1535-0797"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashley C Griffin","raw_affiliation_strings":["Program on Health and Clinical Informatics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program on Health and Clinical Informatics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091400921","display_name":"Ethan Basch","orcid":"https://orcid.org/0000-0003-3813-9318"},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ethan M Basch","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA","Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA","Program on Health and Clinical Informatics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Program on Health and Clinical Informatics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5021279490"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":{"value":3967,"currency":"USD","value_usd":3967},"apc_paid":null,"fwci":2.9693,"has_fulltext":true,"cited_by_count":70,"citation_normalized_percentile":{"value":0.92322091,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"26","issue":"4","first_page":"276","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.8461999893188477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.8461999893188477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10028","display_name":"Topic Modeling","score":0.016100000590085983,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.013399999588727951,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/common-terminology-criteria-for-adverse-events","display_name":"Common Terminology Criteria for Adverse Events","score":0.9149773120880127},{"id":"https://openalex.org/keywords/adverse-effect","display_name":"Adverse effect","score":0.723415195941925},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7230566740036011},{"id":"https://openalex.org/keywords/terminology","display_name":"Terminology","score":0.6624107956886292},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.43733835220336914},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.42398059368133545},{"id":"https://openalex.org/keywords/family-medicine","display_name":"Family medicine","score":0.34633877873420715},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.11596021056175232}],"concepts":[{"id":"https://openalex.org/C2777793932","wikidata":"https://www.wikidata.org/wiki/Q1116229","display_name":"Common Terminology Criteria for Adverse Events","level":3,"score":0.9149773120880127},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.723415195941925},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7230566740036011},{"id":"https://openalex.org/C547195049","wikidata":"https://www.wikidata.org/wiki/Q1725664","display_name":"Terminology","level":2,"score":0.6624107956886292},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43733835220336914},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.42398059368133545},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.34633877873420715},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11596021056175232},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000071066","descriptor_name":"Patient Reported Outcome Measures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071066","descriptor_name":"Patient Reported Outcome Measures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071066","descriptor_name":"Patient Reported Outcome Measures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071066","descriptor_name":"Patient Reported Outcome Measures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004341","descriptor_name":"Drug Evaluation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004341","descriptor_name":"Drug Evaluation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004341","descriptor_name":"Drug Evaluation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004341","descriptor_name":"Drug Evaluation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054547","descriptor_name":"National Cancer Institute (U.S.)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054547","descriptor_name":"National Cancer Institute (U.S.)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054547","descriptor_name":"National Cancer Institute (U.S.)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054547","descriptor_name":"National Cancer Institute (U.S.)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/jamia/ocy169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocy169","pdf_url":"https://academic.oup.com/jamia/article-pdf/26/4/276/34151401/ocy169.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},{"id":"pmid:30840079","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30840079","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association : JAMIA","raw_type":null},{"id":"pmh:oai:europepmc.org:5966809","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6402312","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/jamia/ocy169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocy169","pdf_url":"https://academic.oup.com/jamia/article-pdf/26/4/276/34151401/ocy169.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4403903135","display_name":null,"funder_award_id":"1KL2TR001109","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G52362609","display_name":null,"funder_award_id":"HHSN261201000043C","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8813358451","display_name":null,"funder_award_id":"HHSN261201000063C","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2917197653.pdf","grobid_xml":"https://content.openalex.org/works/W2917197653.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1842042263","https://openalex.org/W2024862171","https://openalex.org/W2056540289","https://openalex.org/W2113464761","https://openalex.org/W2160194473","https://openalex.org/W2164105883","https://openalex.org/W2421891992","https://openalex.org/W2586059174","https://openalex.org/W2590462354","https://openalex.org/W2606000113","https://openalex.org/W2775052471","https://openalex.org/W2810465012","https://openalex.org/W2905878876","https://openalex.org/W2910993323","https://openalex.org/W2970545422","https://openalex.org/W2970619552","https://openalex.org/W2982451723","https://openalex.org/W2990536359","https://openalex.org/W3013843155","https://openalex.org/W3033722597","https://openalex.org/W3144469291","https://openalex.org/W6746856389","https://openalex.org/W6998874797"],"related_works":["https://openalex.org/W4383619592","https://openalex.org/W4311023586","https://openalex.org/W3011133548","https://openalex.org/W4281261911","https://openalex.org/W2157875025","https://openalex.org/W4281949835","https://openalex.org/W3007985759","https://openalex.org/W2299753147","https://openalex.org/W2137935439","https://openalex.org/W2792278937"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1],"study":[2],"sought":[3],"to":[4,34,199,205,229,244,251,255,275],"describe":[5],"patient-entered":[6],"supplemental":[7,85,147,156,213],"information":[8,88,157,214],"on":[9],"symptomatic":[10,86,148,266],"adverse":[11],"events":[12],"(AEs)":[13],"in":[14,41,89],"cancer":[15,49],"clinical":[16],"research":[17],"reported":[18],"via":[19],"a":[20,54,90,200,206,222,269],"National":[21,61],"Cancer":[22,62],"Institute":[23],"software":[24],"system":[25,254],"and":[26,177,203,281],"examine":[27],"the":[28,60,68,79,98,107,188,253],"feasibility":[29],"of":[30,57,67,78,142,164,173,179,187,265],"mapping":[31,258,274],"these":[32],"entries":[33,192,238],"established":[35],"terminologies.":[36],"MATERIALS":[37],"AND":[38],"METHODS:":[39],"Patients":[40],"3":[42],"multicenter":[43],"trials":[44],"electronically":[45],"completed":[46,139],"surveys":[47],"during":[48],"treatment.":[50],"Each":[51],"survey":[52,80,217],"included":[53,146],"prespecified":[55],"subset":[56],"items":[58],"from":[59,106,131],"Institute's":[63],"Patient-Reported":[64],"Outcomes":[65],"version":[66],"Common":[69],"Terminology":[70],"Criteria":[71],"for":[72,114,125,259],"Adverse":[73],"Events":[74],"(PRO-CTCAE).":[75],"Upon":[76],"completion":[77],"items,":[81],"patients":[82,95,119,154],"could":[83,103,120,194,239],"add":[84],"AE":[87,149,260],"free":[91,123,183,190,232,236],"text":[92,124,184,191,233,237,270],"box.":[93],"As":[94],"typed":[96],"into":[97],"box,":[99],"structured":[100,223],"dropdown":[101,224],"terms":[102],"be":[104,195,240],"selected":[105,221],"PRO-CTCAE":[108,201,245],"item":[109],"library":[110],"or":[111,118,246],"Medical":[112],"Dictionary":[113],"Regulatory":[115],"Activities":[116],"(MedDRA),":[117],"type":[121],"unstructured":[122,182,189,231],"submission.":[126],"RESULTS:":[127],"Data":[128],"were":[129],"pooled":[130],"1760":[132],"participants":[133],"(48%":[134],"women;":[135],"78%":[136],"White)":[137],"who":[138],"8892":[140,174,180],"surveys,":[141],"which":[143],"2387":[144],"(26.8%)":[145],"information.":[150],"Overall,":[151],"1024":[152],"(58%)":[153],"entered":[155],"at":[158],"least":[159],"once,":[160],"with":[161,273],"an":[162],"average":[163],"2.3":[165],"per":[166,168],"patient":[167],"study.":[169],"This":[170],"encompassed":[171],"1474":[172],"(16.6%)":[175],"dropdowns":[176],"913":[178],"(10.3%)":[181],"entries.":[185,234],"One-third":[186],"(32%)":[193],"mapped":[196,241],"post":[197,242],"hoc":[198,243],"term":[202],"68%":[204],"MedDRA":[207,247],"term.":[208],"DISCUSSION:":[209],"Participants":[210],"frequently":[211],"added":[212],"beyond":[215],"study-specific":[216],"items.":[218],"Almost":[219],"half":[220],"term,":[225],"although":[226],"many":[227],"opted":[228],"submit":[230],"Most":[235],"terms,":[248],"suggesting":[249],"opportunities":[250],"enhance":[252],"perform":[256],"real-time":[257],"reporting.":[261],"CONCLUSIONS:":[262],"Patient":[263],"reporting":[264],"AEs":[267],"using":[268],"box":[271],"functionality":[272],"existing":[276],"terminologies":[277],"is":[278],"both":[279],"feasible":[280],"informative.":[282]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":5}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}