{"id":"https://openalex.org/W2789496591","doi":"https://doi.org/10.1093/jamia/ocy008","title":"Clinical research informatics: a growing subspecialization of biomedical informatics","display_name":"Clinical research informatics: a growing subspecialization of biomedical informatics","publication_year":2018,"publication_date":"2018-02-23","ids":{"openalex":"https://openalex.org/W2789496591","doi":"https://doi.org/10.1093/jamia/ocy008","mag":"2789496591","pmid":"https://pubmed.ncbi.nlm.nih.gov/31972028"},"language":"en","primary_location":{"id":"doi:10.1093/jamia/ocy008","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocy008","pdf_url":"https://academic.oup.com/jamia/article-pdf/25/3/223/24153805/ocy008.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jamia/article-pdf/25/3/223/24153805/ocy008.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084415954","display_name":"Lucila Ohno\u2010Machado","orcid":"https://orcid.org/0000-0002-8005-7327"},"institutions":[{"id":"https://openalex.org/I4210121117","display_name":"Health Affairs","ror":"https://ror.org/02fkh1w66","country_code":"US","type":"other","lineage":["https://openalex.org/I4210121117"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lucila Ohno-Machado","raw_affiliation_strings":["Editor-in-Chief"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Editor-in-Chief","institution_ids":["https://openalex.org/I4210121117"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5084415954"],"corresponding_institution_ids":["https://openalex.org/I4210121117"],"apc_list":{"value":3967,"currency":"USD","value_usd":3967},"apc_paid":null,"fwci":0.4267,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.72909572,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"25","issue":"3","first_page":"223","last_page":"223"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10350","display_name":"Electronic Health Records Systems","score":0.8526999950408936,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10350","display_name":"Electronic Health Records Systems","score":0.8526999950408936,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.7763000130653381,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.739799976348877,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/informatics","display_name":"Informatics","score":0.6924287676811218},{"id":"https://openalex.org/keywords/health-informatics","display_name":"Health informatics","score":0.6631050109863281},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.488665372133255},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.417947381734848},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.37087270617485046},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.35394859313964844},{"id":"https://openalex.org/keywords/political-science","display_name":"Political science","score":0.18175512552261353},{"id":"https://openalex.org/keywords/nursing","display_name":"Nursing","score":0.13283029198646545},{"id":"https://openalex.org/keywords/public-health","display_name":"Public health","score":0.11203062534332275}],"concepts":[{"id":"https://openalex.org/C191630685","wikidata":"https://www.wikidata.org/wiki/Q4027615","display_name":"Informatics","level":2,"score":0.6924287676811218},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.6631050109863281},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.488665372133255},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.417947381734848},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.37087270617485046},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35394859313964844},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.18175512552261353},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.13283029198646545},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.11203062534332275},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1093/jamia/ocy008","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocy008","pdf_url":"https://academic.oup.com/jamia/article-pdf/25/3/223/24153805/ocy008.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},{"id":"pmid:31972028","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31972028","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association : JAMIA","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7651919","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7651919","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Am Med Inform Assoc","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/jamia/ocy008","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocy008","pdf_url":"https://academic.oup.com/jamia/article-pdf/25/3/223/24153805/ocy008.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2789496591.pdf","grobid_xml":"https://content.openalex.org/works/W2789496591.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2397677514","https://openalex.org/W1495820741","https://openalex.org/W2990177913","https://openalex.org/W1451471413","https://openalex.org/W2138729887","https://openalex.org/W2401910071","https://openalex.org/W4323056170","https://openalex.org/W2126732312","https://openalex.org/W4302329558","https://openalex.org/W2096609042"],"abstract_inverted_index":{"Biomedical":[0],"informatics":[1,21,29,85,89,509],"has":[2],"evolved":[3],"so":[4],"rapidly":[5],"in":[6,40,61,174,187,219,225,365,419,436,501,533],"the":[7,12,58,304,315,334,390,420,498],"past":[8],"two":[9,347],"decades":[10],"that":[11,73,156,177,281,506,529],"emergence":[13],"of":[14,26,43,52,57,234,271,276,306,317,342,392,407,422,517],"subspecialization":[15],"areas":[16],"such":[17],"as":[18,65,67],"clinical":[19,27,62,77,182,220,258,321,507,555],"research":[20,28,63,84,423,454,499,508],"was":[22],"natural.":[23],"The":[24,229],"scope":[25],"is":[30,46,74,184,191,240,349,461],"also":[31,409],"broad,":[32],"and":[33,95,99,126,129,132,163,213,333,384,397,416,441,535,554],"it":[34,45,460],"will":[35,510,548],"not":[36,262,462],"be":[37,331,339,363,513,531,549],"surprising":[38],"if":[39],"a":[41,71,108,137,164,241,252,290,393,401,429,475,486,514],"couple":[42],"years":[44],"further":[47],"subspecialized.":[48],"In":[49],"this":[50,246,502],"issue":[51,406],"JAMIA,":[53],"we":[54,504],"bring":[55],"some":[56],"best":[59],"work":[60],"informatics,":[64],"well":[66],"related":[68,412],"articles":[69,411],"on":[70,323,389,446,468,497,551],"technology":[72],"behind":[75],"many":[76,458],"applications:":[78],"natural":[79],"language":[80],"processing":[81],"(NLP).":[82],"Clinical":[83],"applications":[86],"typically":[87],"involve":[88],"approaches":[90],"to":[91,139,194,206,223,237,330,338,345,413,432,466,512,522,543],"collect,":[92],"process,":[93],"analyze,":[94],"display":[96],"health":[97,145,487],"care":[98],"biomedical":[100,382,518],"data":[101,115,196,264,294,308,328,356,402,417,494],"for":[102,110,116,124,159,197,231,254,267,292,296,309,320,359,380,400,453,477,492,538],"research.":[103,198,310],"Adams":[104],"(p.":[105,119,134,152,169,200,215,249,287,301,312,353,372,386,426,443,472,483],"295)":[106],"describes":[107,374,474,485],"system":[109,227],"collecting":[111],"mechanical":[112],"ventilator":[113],"waveform":[114],"research,":[117,268],"Brokamp":[118],"309)":[120],"proposes":[121,136,289],"an":[122,343,375,450,524],"approach":[123,431],"geocoding":[125],"characterizing":[127],"community":[128],"environmental":[130],"exposures,":[131],"Hripcsak":[133],"289)":[135],"way":[138],"conduct":[140],"high-fidelity":[141],"phenotyping":[142],"from":[143,209],"electronic":[144],"records":[146],"(EHRs).":[147],"An":[148],"analysis":[149,396],"by":[150,167,351],"Boland":[151],"275)":[153],"uncovers":[154],"exposures":[155],"are":[157,265,357],"responsible":[158],"birth":[160],"season\u2013disease":[161],"effects,":[162],"method":[165],"proposed":[166],"Chen":[168],"345)":[170],"targets":[171],"bias":[172],"reduction":[173],"association":[175],"studies":[176,217],"use":[178],"EHR":[179],"data.":[180],"As":[181],"text":[183],"still":[185],"rich":[186],"narrative":[188],"text,":[189],"NLP":[190,226,235,259],"frequently":[192],"used":[193],"preprocess":[195],"Ramanathan":[199],"321)":[201],"uses":[202],"hierarchical":[203],"attention":[204],"networks":[205],"extract":[207],"information":[208],"cancer":[210],"pathology":[211],"reports,":[212],"Sohn":[214],"353)":[216],"variations":[218],"documentation":[221],"due":[222],"issues":[224],"portability.":[228],"need":[230,329,337],"resource-consuming":[232],"customization":[233],"systems":[236,528,537,553],"increase":[238],"portability":[239],"known":[242],"challenge.":[243],"To":[244],"address":[245],"challenge,":[247],"Soysal":[248],"331)":[250],"presents":[251,410],"toolkit":[253],"efficiently":[255],"building":[256],"customized":[257],"pipelines.":[260],"However,":[261,457],"all":[263],"ready":[266,358],"either":[269],"because":[270,275],"their":[272,283],"quality":[273,305],"or":[274,278,368,464],"privacy":[277,415,434],"other":[279],"concerns":[280],"prevent":[282],"public":[284],"disclosure.":[285],"Shang":[286],"248)":[288],"framework":[291],"evaluating":[293],"suitability":[295],"observational":[297],"studies,":[298],"while":[299],"Smith":[300],"224)":[302],"assesses":[303],"administrative":[307],"Weng":[311],"239)":[313],"evaluates":[314],"representativeness":[316],"eligible":[318],"patients":[319],"trials":[322],"type":[324],"2":[325],"diabetes.":[326],"Additionally,":[327],"standardized,":[332],"various":[335],"standards":[336,348],"reconciled.":[340],"Utilization":[341],"ontology":[344],"unify":[346],"demonstrated":[350],"Campbell":[352],"259).":[354],"Once":[355],"dissemination,":[360],"they":[361],"can":[362,530],"reused":[364],"new":[366],"exploratory":[367],"confirmatory":[369],"analyses:":[370],"Xu":[371],"300)":[373],"open":[376],"source":[377],"discovery":[378],"index":[379],"finding":[381],"datasets,":[383],"Johnson":[385],"337)":[387],"reports":[388,445],"results":[391],"user":[394],"needs":[395],"usability":[398],"assessment":[399],"search":[403],"engine.":[404],"This":[405],"JAMIA":[408],"participant":[414],"security":[418],"context":[421],"applications.":[424],"O\u2019Keefe":[425],"315)":[427],"utilizes":[428],"checklist":[430],"assess":[433],"risks":[435],"publications":[437],"about":[438],"population":[439],"health,":[440],"Harle":[442],"360)":[444],"patient":[447],"preferences":[448],"regarding":[449],"e-consent":[451],"application":[452],"involving":[455],"EHRs.":[456,480],"times":[459],"practical":[463],"necessary":[465],"operate":[467],"real":[469],"records:":[470],"Walonoski":[471],"230)":[473],"tool":[476],"generating":[478],"synthetic":[479],"Finally,":[481],"Peisert":[482],"267)":[484],"science":[488],"secure":[489],"network":[490],"design":[491],"big":[493],"analysis.":[495],"Based":[496],"published":[500],"issue,":[503],"predict":[505],"continue":[511],"growing":[515],"subspecialty":[516],"informatics.":[519],"We":[520],"hope":[521],"see":[523],"increasing":[525],"trend":[526],"toward":[527],"embedded":[532],"patient-":[534],"clinician-facing":[536],"real-time":[539],"utilization.":[540],"Stay":[541],"tuned":[542],"JAMIA\u2019s":[544],"next":[545],"issues,":[546],"which":[547],"focused":[550],"patient-centered":[552],"decision":[556],"support":[557],"systems.":[558]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2025-10-10T00:00:00"}