{"id":"https://openalex.org/W3135761017","doi":"https://doi.org/10.1093/jamia/ocab019","title":"DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions","display_name":"DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions","publication_year":2021,"publication_date":"2021-02-08","ids":{"openalex":"https://openalex.org/W3135761017","doi":"https://doi.org/10.1093/jamia/ocab019","mag":"3135761017","pmid":"https://pubmed.ncbi.nlm.nih.gov/33712848"},"language":"en","primary_location":{"id":"doi:10.1093/jamia/ocab019","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jamia/ocab019","pdf_url":null,"source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8279788","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008192944","display_name":"Patrick Wu","orcid":"https://orcid.org/0000-0002-1437-6688"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick Wu","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","Medical Scientist Training Program, Vanderbilt University School of Medicine , Nashville, Tennessee,","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, Tennessee, USA"],"raw_orcid":"https://orcid.org/0000-0002-1437-6688","affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Medical Scientist Training Program, Vanderbilt University School of Medicine , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002607014","display_name":"Scott D. Nelson","orcid":"https://orcid.org/0000-0002-8435-5065"},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott D Nelson","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","HealthIT, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","HealthIT, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"HealthIT, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"HealthIT, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025971024","display_name":"Juan Zhao","orcid":"https://orcid.org/0000-0003-1429-0662"},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juan Zhao","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018729944","display_name":"Cosby A. Stone","orcid":"https://orcid.org/0000-0002-1888-4188"},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cosby A Stone Jr","raw_affiliation_strings":["Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine , Vanderbilt University Medical Center, Nashville, Tennessee,","Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine , Vanderbilt University Medical Center, Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018427711","display_name":"QiPing Feng","orcid":"https://orcid.org/0000-0002-6213-793X"},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"QiPing Feng","raw_affiliation_strings":["Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011155701","display_name":"Qingxia Chen","orcid":"https://orcid.org/0000-0003-0507-1847"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210135086","display_name":"Tennessee Oncology","ror":"https://ror.org/03754ky26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135086"]},{"id":"https://openalex.org/I4210156451","display_name":"Nashville Oncology Associates","ror":"https://ror.org/05syrg433","country_code":"US","type":"other","lineage":["https://openalex.org/I4210156451"]},{"id":"https://openalex.org/I4210158012","display_name":"Tennessee Clinical Research Center","ror":"https://ror.org/05jsaxg97","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210158012"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qingxia Chen","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Biostatistics, Vanderbilt University School of , Nashville, Tennessee,","Medicine , Nashville, Tennessee,","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Biostatistics, Vanderbilt University School of , Nashville, Tennessee,","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Medicine , Nashville, Tennessee,","institution_ids":["https://openalex.org/I4210135086","https://openalex.org/I4210156451","https://openalex.org/I4210158012"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020730826","display_name":"Eric Larson","orcid":"https://orcid.org/0000-0003-2173-4321"},"institutions":[{"id":"https://openalex.org/I189957204","display_name":"University of South Dakota","ror":"https://ror.org/0043h8f16","country_code":"US","type":"education","lineage":["https://openalex.org/I189957204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric A Larson","raw_affiliation_strings":["Department of Medicine, University of South Dakota Sanford School of Medicine , Sioux Falls, South Dakota,","Department of Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of South Dakota Sanford School of Medicine , Sioux Falls, South Dakota,","institution_ids":["https://openalex.org/I189957204"]},{"raw_affiliation_string":"Department of Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota, USA","institution_ids":["https://openalex.org/I189957204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028708641","display_name":"Bingshan Li","orcid":"https://orcid.org/0000-0003-2129-168X"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bingshan Li","raw_affiliation_strings":["Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine , Nashville, Tennessee,","Vanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Vanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine , Nashville, Tennessee,","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Vanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Vanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036388273","display_name":"Nancy J. Cox","orcid":"https://orcid.org/0000-0001-9315-0830"},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy J Cox","raw_affiliation_strings":["Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","Vanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","Vanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Vanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Vanderbilt Genetics Institute, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102712577","display_name":"C. Stein","orcid":"https://orcid.org/0009-0008-8107-578X"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C Michael Stein","raw_affiliation_strings":["Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Pharmacology, Vanderbilt University School of Medicine , Nashville, Tennessee,","Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine , Nashville, Tennessee,","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080985934","display_name":"Elizabeth J. Phillips","orcid":"https://orcid.org/0000-0002-7623-3383"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth J Phillips","raw_affiliation_strings":["Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Pharmacology, Vanderbilt University School of Medicine , Nashville, Tennessee,","Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA","Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine , Nashville, Tennessee,","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058141203","display_name":"Dan M. Roden","orcid":"https://orcid.org/0000-0002-6302-0389"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dan M Roden","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Pharmacology, Vanderbilt University School of Medicine , Nashville, Tennessee,","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Medicine, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine , Nashville, Tennessee,","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070908224","display_name":"Joshua C. Denny","orcid":"https://orcid.org/0000-0002-3049-7332"},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110704","display_name":"National Institute of Nursing Research","ror":"https://ror.org/01y3zfr79","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110704"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua C Denny","raw_affiliation_strings":["All of Us Research Program, National Institutes of Health , Bethesda, Maryland,","Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","All of Us Research Program, National Institutes of Health, Bethesda, Maryland, USA","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"All of Us Research Program, National Institutes of Health , Bethesda, Maryland,","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110704"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"All of Us Research Program, National Institutes of Health, Bethesda, Maryland, USA","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040262386","display_name":"Wei\u2010Qi Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wei-Qi Wei","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee,","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5040262386"],"corresponding_institution_ids":["https://openalex.org/I901861585"],"apc_list":{"value":3967,"currency":"USD","value_usd":3967},"apc_paid":null,"fwci":1.6951,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.81312189,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"28","issue":"7","first_page":"1421","last_page":"1430"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.6728000044822693,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.6728000044822693,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.19619999825954437,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.0203000009059906,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amlodipine","display_name":"Amlodipine","score":0.6829781532287598},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.6611851453781128},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6039366126060486},{"id":"https://openalex.org/keywords/drug-allergy","display_name":"Drug allergy","score":0.5160664916038513},{"id":"https://openalex.org/keywords/simvastatin","display_name":"Simvastatin","score":0.48000067472457886},{"id":"https://openalex.org/keywords/hydrochlorothiazide","display_name":"Hydrochlorothiazide","score":0.42411404848098755},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.38596147298812866},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.32010629773139954},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.2995924651622772},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.20224863290786743},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.09364739060401917}],"concepts":[{"id":"https://openalex.org/C2779646130","wikidata":"https://www.wikidata.org/wiki/Q411347","display_name":"Amlodipine","level":3,"score":0.6829781532287598},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.6611851453781128},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6039366126060486},{"id":"https://openalex.org/C2779060952","wikidata":"https://www.wikidata.org/wiki/Q2068896","display_name":"Drug allergy","level":3,"score":0.5160664916038513},{"id":"https://openalex.org/C2776329913","wikidata":"https://www.wikidata.org/wiki/Q670131","display_name":"Simvastatin","level":2,"score":0.48000067472457886},{"id":"https://openalex.org/C2780361556","wikidata":"https://www.wikidata.org/wiki/Q423930","display_name":"Hydrochlorothiazide","level":3,"score":0.42411404848098755},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38596147298812866},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.32010629773139954},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2995924651622772},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20224863290786743},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.09364739060401917}],"mesh":[{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051188","descriptor_name":"Knowledge Bases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/jamia/ocab019","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jamia/ocab019","pdf_url":null,"source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},{"id":"pmid:33712848","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33712848","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association : JAMIA","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8279788","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8279788","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Am Med Inform Assoc","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8279788","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8279788","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Am Med Inform Assoc","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G129402337","display_name":null,"funder_award_id":"K12 HS026395","funder_id":"https://openalex.org/F4320332177","funder_display_name":"Agency for Healthcare Research and Quality"},{"id":"https://openalex.org/G1407223514","display_name":null,"funder_award_id":"R01 GM139891","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G1612602199","display_name":null,"funder_award_id":"T15 LM007450","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G1730842257","display_name":null,"funder_award_id":"UL1 TR000445","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2310098089","display_name":null,"funder_award_id":"P50 GM115305","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2779203831","display_name":null,"funder_award_id":"R01 HL133786","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3759482195","display_name":null,"funder_award_id":"R01 GM120523","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3792298299","display_name":null,"funder_award_id":"R35 GM131770","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4173387091","display_name":null,"funder_award_id":"R01 HL133786","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4509514859","display_name":null,"funder_award_id":"T15 LM007450","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4602683103","display_name":null,"funder_award_id":"R01 LM010685","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4731208165","display_name":null,"funder_award_id":"K12HS026395","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5114459058","display_name":null,"funder_award_id":"R01 LM010685","funder_id":"https://openalex.org/F4320337372","funder_display_name":"U.S. National Library of Medicine"},{"id":"https://openalex.org/G5567961302","display_name":null,"funder_award_id":"T32GM007347","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5898134747","display_name":null,"funder_award_id":"T32 GM152284","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6652461426","display_name":"Exploring Statin Pleiotropic Effects within a Very Large EHR Cohort","funder_award_id":"16SDG27490014","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G6765605901","display_name":null,"funder_award_id":"U01 HG011181","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G6990348227","display_name":null,"funder_award_id":"P50 GM115305","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7095014659","display_name":null,"funder_award_id":"R35 GM131770","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7276244327","display_name":null,"funder_award_id":"2UL1 TR000445-06","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G7783315419","display_name":null,"funder_award_id":"R25 GM062459","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8472747755","display_name":null,"funder_award_id":"T32 GM007347","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332177","display_name":"Agency for Healthcare Research and Quality","ror":"https://ror.org/03jmfdf59"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337372","display_name":"U.S. National Library of Medicine","ror":"https://ror.org/0060t0j89"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W34678172","https://openalex.org/W126464923","https://openalex.org/W169580636","https://openalex.org/W997324903","https://openalex.org/W1135673779","https://openalex.org/W1507651605","https://openalex.org/W1523152575","https://openalex.org/W1897770946","https://openalex.org/W1934602670","https://openalex.org/W1969208427","https://openalex.org/W1978406883","https://openalex.org/W1992713697","https://openalex.org/W2004281677","https://openalex.org/W2006776184","https://openalex.org/W2010783249","https://openalex.org/W2013416277","https://openalex.org/W2013763380","https://openalex.org/W2024862171","https://openalex.org/W2035410307","https://openalex.org/W2076993862","https://openalex.org/W2092690624","https://openalex.org/W2096252540","https://openalex.org/W2106618845","https://openalex.org/W2112054734","https://openalex.org/W2112649925","https://openalex.org/W2119002393","https://openalex.org/W2121111666","https://openalex.org/W2128043538","https://openalex.org/W2130547542","https://openalex.org/W2135642446","https://openalex.org/W2150627342","https://openalex.org/W2168528736","https://openalex.org/W2232325453","https://openalex.org/W2310115806","https://openalex.org/W2530398232","https://openalex.org/W2535158955","https://openalex.org/W2557200792","https://openalex.org/W2590778886","https://openalex.org/W2732772009","https://openalex.org/W2746326048","https://openalex.org/W2767891136","https://openalex.org/W2905331745","https://openalex.org/W2943625371","https://openalex.org/W2983854304","https://openalex.org/W2991379615","https://openalex.org/W2996707454","https://openalex.org/W3004612364","https://openalex.org/W3025835236","https://openalex.org/W3082285786","https://openalex.org/W4231521050","https://openalex.org/W6627460192","https://openalex.org/W6968746123"],"related_works":["https://openalex.org/W2956976130","https://openalex.org/W2110584490","https://openalex.org/W2745584358","https://openalex.org/W2356526628","https://openalex.org/W3028639709","https://openalex.org/W114969519","https://openalex.org/W1795719079","https://openalex.org/W1507998839","https://openalex.org/W1985980299","https://openalex.org/W2123752372"],"abstract_inverted_index":{"OBJECTIVE:":[0],"We":[1,75],"developed":[2],"and":[3,68,87,101,121,125,137,187],"evaluated":[4,76],"Drug-Drug":[5],"Interaction":[6],"Wide":[7],"Association":[8],"Study":[9],"(DDIWAS).":[10],"This":[11],"novel":[12,94,132],"method":[13],"detects":[14],"potential":[15,35,60,93,131,184],"drug-drug":[16],"interactions":[17,133],"(DDIs)":[18],"by":[19],"leveraging":[20],"data":[21],"from":[22,161],"the":[23,48,77,103,155,183],"electronic":[24],"health":[25],"record":[26],"(EHR)":[27],"allergy":[28,49,163,174],"list.":[29,50],"MATERIALS":[30],"AND":[31],"METHODS:":[32],"To":[33,91],"identify":[34],"DDIs,":[36,95],"DDIWAS":[37,106,128,144,181],"scans":[38],"for":[39,59,123],"drug":[40],"pairs":[41],"that":[42],"are":[43,176],"frequently":[44],"documented":[45],"together":[46],"on":[47],"Using":[51],"deidentified":[52],"medical":[53],"records,":[54],"we":[55,96,153],"tested":[56],"616":[57],"drugs":[58],"DDIs":[61,82,118,167],"with":[62],"simvastatin":[63,124],"(a":[64,70],"common":[65,71],"lipid-lowering":[66],"drug)":[67],"amlodipine":[69],"blood-pressure":[72],"lowering":[73],"drug).":[74],"performance":[78],"to":[79,115,142,165,185],"rediscover":[80],"known":[81,109,117],"using":[83],"existing":[84,162],"knowledge":[85],"bases":[86],"domain":[88],"expert":[89],"review.":[90],"validate":[92,188],"manually":[97],"reviewed":[98],"patient":[99],"charts":[100],"searched":[102],"literature.":[104],"RESULTS:":[105],"replicated":[107],"34":[108],"DDIs.":[110],"The":[111],"positive":[112],"predictive":[113],"value":[114,156],"detect":[116,166,186],"was":[119],"0.85":[120],"0.86":[122],"amlodipine,":[126],"respectively.":[127],"also":[129],"discovered":[130],"between":[134],"simvastatin-hydrochlorothiazide,":[135],"amlodipine-omeprazole,":[136],"amlodipine-valacyclovir.":[138],"A":[139],"software":[140],"package":[141],"conduct":[143],"is":[145],"publicly":[146],"available.":[147],"CONCLUSIONS:":[148],"In":[149],"this":[150],"proof-of-concept":[151],"study,":[152],"demonstrate":[154],"of":[157],"incorporating":[158],"information":[159],"mined":[160],"lists":[164,175],"in":[168,179],"a":[169],"real-world":[170],"clinical":[171],"setting.":[172],"Since":[173],"routinely":[177],"collected":[178],"EHRs,":[180],"has":[182],"DDI":[189],"signals":[190],"across":[191],"institutions.":[192]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5}],"updated_date":"2026-07-28T07:46:37.118299","created_date":"2025-10-10T00:00:00"}
