{"id":"https://openalex.org/W4400336893","doi":"https://doi.org/10.1093/gpbjnl/qzae033","title":"Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung Cancer","display_name":"Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung Cancer","publication_year":2024,"publication_date":"2024-04-01","ids":{"openalex":"https://openalex.org/W4400336893","doi":"https://doi.org/10.1093/gpbjnl/qzae033","pmid":"https://pubmed.ncbi.nlm.nih.gov/38961535"},"language":"en","primary_location":{"id":"doi:10.1093/gpbjnl/qzae033","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gpbjnl/qzae033","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/gpbjnl/qzae033","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056453210","display_name":"Zitian Huo","orcid":"https://orcid.org/0000-0002-7368-0831"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zitian Huo","raw_affiliation_strings":["Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","National Health Commission Key Laboratory of Respiratory Diseases, Tongji Hosptial, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]},{"raw_affiliation_string":"National Health Commission Key Laboratory of Respiratory Diseases, Tongji Hosptial, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086773173","display_name":"Yaqi Duan","orcid":"https://orcid.org/0000-0002-2392-5642"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaqi Duan","raw_affiliation_strings":["Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","National Health Commission Key Laboratory of Respiratory Diseases, Tongji Hosptial, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]},{"raw_affiliation_string":"National Health Commission Key Laboratory of Respiratory Diseases, Tongji Hosptial, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091090838","display_name":"Dongdong Zhan","orcid":"https://orcid.org/0000-0002-0704-8782"},"institutions":[{"id":"https://openalex.org/I4210150111","display_name":"Dian Diagnostics (China)","ror":"https://ror.org/05rbz8029","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210150111"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongdong Zhan","raw_affiliation_strings":["Beijing Pineal Diagnostics Co ., Ltd., Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"Beijing Pineal Diagnostics Co ., Ltd., Beijing 102206, China","institution_ids":["https://openalex.org/I4210150111"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103275661","display_name":"Xizhen Xu","orcid":"https://orcid.org/0009-0000-3222-6862"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xizhen Xu","raw_affiliation_strings":["Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065750513","display_name":"Nairen Zheng","orcid":"https://orcid.org/0000-0002-3952-1570"},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Nairen Zheng","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China","institution_ids":["https://openalex.org/I4210149540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101845597","display_name":"Jing Cai","orcid":"https://orcid.org/0000-0001-8002-2645"},"institutions":[{"id":"https://openalex.org/I4210155511","display_name":"First Affiliated Hospital of Henan University","ror":"https://ror.org/0536rsk67","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210155511"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Cai","raw_affiliation_strings":["Institution of Pathology, The First Affiliated Hospital of Henan University , Kaifeng 475001, China"],"affiliations":[{"raw_affiliation_string":"Institution of Pathology, The First Affiliated Hospital of Henan University , Kaifeng 475001, China","institution_ids":["https://openalex.org/I4210155511"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005306533","display_name":"Ruifang Sun","orcid":"https://orcid.org/0000-0002-4791-3734"},"institutions":[{"id":"https://openalex.org/I4210102673","display_name":"Shanxi Provincial Cancer Hospital","ror":"https://ror.org/01790dx02","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210102673"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruifang Sun","raw_affiliation_strings":["Department of Tumor Biobank, Shanxi Cancer Hospital , Taiyuan 030013, China"],"affiliations":[{"raw_affiliation_string":"Department of Tumor Biobank, Shanxi Cancer Hospital , Taiyuan 030013, China","institution_ids":["https://openalex.org/I4210102673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101659529","display_name":"Jianping Wang","orcid":"https://orcid.org/0000-0001-6142-7153"},"institutions":[{"id":"https://openalex.org/I10535382","display_name":"Chongqing University of Posts and Telecommunications","ror":"https://ror.org/03dgaqz26","country_code":"CN","type":"education","lineage":["https://openalex.org/I10535382"]},{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianping Wang","raw_affiliation_strings":["Chongqing Key Laboratory of Big Data for Bio Intelligence, School of Bioinformation, Chongqing University of Posts and Telecommunications , Chongqing 400065, China","State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"Chongqing Key Laboratory of Big Data for Bio Intelligence, School of Bioinformation, Chongqing University of Posts and Telecommunications , Chongqing 400065, China","institution_ids":["https://openalex.org/I10535382"]},{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China","institution_ids":["https://openalex.org/I4210149540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087579119","display_name":"Fang Qin Cheng","orcid":"https://orcid.org/0000-0003-2257-8236"},"institutions":[{"id":"https://openalex.org/I4210150111","display_name":"Dian Diagnostics (China)","ror":"https://ror.org/05rbz8029","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210150111"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fang Cheng","raw_affiliation_strings":["Beijing Pineal Diagnostics Co ., Ltd., Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"Beijing Pineal Diagnostics Co ., Ltd., Beijing 102206, China","institution_ids":["https://openalex.org/I4210150111"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102824841","display_name":"Zhan Gao","orcid":"https://orcid.org/0009-0001-9697-6547"},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhan Gao","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China","institution_ids":["https://openalex.org/I4210149540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028311030","display_name":"Caixia Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Caixia Xu","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China","institution_ids":["https://openalex.org/I4210149540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016522135","display_name":"Wanlin Liu","orcid":"https://orcid.org/0000-0002-4116-2597"},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanlin Liu","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China","institution_ids":["https://openalex.org/I4210149540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069552335","display_name":"Yuting Dong","orcid":"https://orcid.org/0000-0003-0886-9221"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuting Dong","raw_affiliation_strings":["Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021185104","display_name":"Sailong Ma","orcid":"https://orcid.org/0009-0007-5118-6991"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sailong Ma","raw_affiliation_strings":["Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","National Health Commission Key Laboratory of Respiratory Diseases, Tongji Hosptial, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]},{"raw_affiliation_string":"National Health Commission Key Laboratory of Respiratory Diseases, Tongji Hosptial, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069265011","display_name":"Qian Zhang","orcid":"https://orcid.org/0000-0002-0869-3951"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Zhang","raw_affiliation_strings":["Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031500488","display_name":"Yiyun Zheng","orcid":"https://orcid.org/0000-0001-8103-3688"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiyun Zheng","raw_affiliation_strings":["Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010299612","display_name":"Liping Lou","orcid":"https://orcid.org/0000-0002-9542-568X"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liping Lou","raw_affiliation_strings":["Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102891257","display_name":"Dong Kuang","orcid":"https://orcid.org/0000-0001-9568-0333"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dong Kuang","raw_affiliation_strings":["Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103259700","display_name":"Qian Chu","orcid":"https://orcid.org/0000-0001-8192-7630"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Chu","raw_affiliation_strings":["Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008594043","display_name":"Jun Qin","orcid":null},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4210150111","display_name":"Dian Diagnostics (China)","ror":"https://ror.org/05rbz8029","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210150111"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Qin","raw_affiliation_strings":["Beijing Pineal Diagnostics Co ., Ltd., Beijing 102206, China","State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"Beijing Pineal Diagnostics Co ., Ltd., Beijing 102206, China","institution_ids":["https://openalex.org/I4210150111"]},{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China","institution_ids":["https://openalex.org/I4210149540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014440144","display_name":"Guoping Wang","orcid":"https://orcid.org/0009-0000-6472-0849"},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guoping Wang","raw_affiliation_strings":["Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","National Health Commission Key Laboratory of Respiratory Diseases, Tongji Hosptial, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641","https://openalex.org/I4210160344"]},{"raw_affiliation_string":"National Health Commission Key Laboratory of Respiratory Diseases, Tongji Hosptial, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100364926","display_name":"Yi Wang","orcid":"https://orcid.org/0000-0002-2088-2085"},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Wang","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics , Beijing 102206, China","institution_ids":["https://openalex.org/I4210149540"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":22,"corresponding_author_ids":["https://openalex.org/A5056453210"],"corresponding_institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":3.3038,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.93576532,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"22","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.9830999970436096,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/risk-stratification","display_name":"Risk stratification","score":0.7200373411178589},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"Lung cancer","score":0.5467480421066284},{"id":"https://openalex.org/keywords/stratification","display_name":"Stratification (seeds)","score":0.5375485420227051},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.47241178154945374},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.4685477018356323},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.44228994846343994},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.3280808925628662},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2500571310520172}],"concepts":[{"id":"https://openalex.org/C3020404979","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk stratification","level":2,"score":0.7200373411178589},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5467480421066284},{"id":"https://openalex.org/C192943249","wikidata":"https://www.wikidata.org/wiki/Q1893382","display_name":"Stratification (seeds)","level":5,"score":0.5375485420227051},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47241178154945374},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4685477018356323},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44228994846343994},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3280808925628662},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2500571310520172},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C3527866","wikidata":"https://www.wikidata.org/wiki/Q162267","display_name":"Dormancy","level":3,"score":0.0},{"id":"https://openalex.org/C88548481","wikidata":"https://www.wikidata.org/wiki/Q2397491","display_name":"Seed dormancy","level":4,"score":0.0},{"id":"https://openalex.org/C100701293","wikidata":"https://www.wikidata.org/wiki/Q193838","display_name":"Germination","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D055752","descriptor_name":"Small Cell Lung Carcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/gpbjnl/qzae033","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gpbjnl/qzae033","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},{"id":"pmid:38961535","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38961535","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, proteomics & bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11423856","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11423856","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11423856/pdf/qzae033.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Genomics Proteomics Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/gpbjnl/qzae033","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gpbjnl/qzae033","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1323466666","display_name":null,"funder_award_id":"81974016","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2007109882","display_name":null,"funder_award_id":"82072597","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3085993365","display_name":null,"funder_award_id":"(Grant No.","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G391238517","display_name":null,"funder_award_id":", and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4120274581","display_name":null,"funder_award_id":"81874237","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5474513853","display_name":null,"funder_award_id":"31970725","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5486152420","display_name":null,"funder_award_id":"202002","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5939423041","display_name":null,"funder_award_id":"Technology","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6126095023","display_name":null,"funder_award_id":"31770892","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6226218505","display_name":null,"funder_award_id":"2017YFA0505103","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7726157001","display_name":null,"funder_award_id":"Grant No.","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8218031721","display_name":null,"funder_award_id":"2017YFA","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8635972800","display_name":null,"funder_award_id":"62131009","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G935120361","display_name":null,"funder_award_id":"31870828","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W1527997039","https://openalex.org/W1615432648","https://openalex.org/W1778117100","https://openalex.org/W1810363312","https://openalex.org/W1903523058","https://openalex.org/W1995404170","https://openalex.org/W1997232290","https://openalex.org/W2023171799","https://openalex.org/W2043677605","https://openalex.org/W2073124245","https://openalex.org/W2084833108","https://openalex.org/W2090307950","https://openalex.org/W2094396436","https://openalex.org/W2102514436","https://openalex.org/W2156990811","https://openalex.org/W2161706122","https://openalex.org/W2165994277","https://openalex.org/W2166462159","https://openalex.org/W2307888262","https://openalex.org/W2409565356","https://openalex.org/W2414012528","https://openalex.org/W2417035212","https://openalex.org/W2479269395","https://openalex.org/W2500484015","https://openalex.org/W2502521711","https://openalex.org/W2542466015","https://openalex.org/W2588648082","https://openalex.org/W2605964154","https://openalex.org/W2612354780","https://openalex.org/W2765782352","https://openalex.org/W2767246174","https://openalex.org/W2770858121","https://openalex.org/W2778183218","https://openalex.org/W2793783646","https://openalex.org/W2796432287","https://openalex.org/W2809972762","https://openalex.org/W2810630532","https://openalex.org/W2908066383","https://openalex.org/W2909516037","https://openalex.org/W2918023653","https://openalex.org/W2928432651","https://openalex.org/W2969646491","https://openalex.org/W2976235020","https://openalex.org/W2977392388","https://openalex.org/W2977528366","https://openalex.org/W3006467062","https://openalex.org/W3041397352","https://openalex.org/W3045753156","https://openalex.org/W3046546808","https://openalex.org/W3081768459","https://openalex.org/W3090613431","https://openalex.org/W3120238974","https://openalex.org/W3122848755","https://openalex.org/W3124749091","https://openalex.org/W3135101421","https://openalex.org/W3135578245","https://openalex.org/W3183016023","https://openalex.org/W3205820819","https://openalex.org/W3206940911","https://openalex.org/W4200477716","https://openalex.org/W4241962913","https://openalex.org/W4297251744","https://openalex.org/W4323923631","https://openalex.org/W6638156285","https://openalex.org/W6638288342","https://openalex.org/W6684367941","https://openalex.org/W6714471372","https://openalex.org/W7073708602"],"related_works":["https://openalex.org/W4386554877","https://openalex.org/W4236138976","https://openalex.org/W3203136021","https://openalex.org/W3173424037","https://openalex.org/W4239581157","https://openalex.org/W2393041552","https://openalex.org/W2036103646","https://openalex.org/W2033590167","https://openalex.org/W1583810757","https://openalex.org/W2001086065"],"abstract_inverted_index":{"Small":[0],"cell":[1],"lung":[2],"cancer":[3,11],"(SCLC)":[4],"is":[5],"a":[6],"highly":[7],"malignant":[8],"and":[9,16,33,42,48,59,94,163,189],"heterogeneous":[10],"with":[12,44],"limited":[13],"therapeutic":[14,124],"options":[15],"prognosis":[17,187],"prediction":[18,154,188],"models.":[19],"Here,":[20],"we":[21],"analyzed":[22],"formalin-fixed,":[23],"paraffin-embedded":[24],"(FFPE)":[25],"samples":[26,83],"of":[27,99,141,145],"surgical":[28,93],"resections":[29],"by":[30],"proteomic":[31,38,52],"profiling,":[32],"stratified":[34],"SCLC":[35,146],"into":[36],"three":[37],"subtypes":[39],"(S-I,":[40],"S-II,":[41],"S-III)":[43],"distinct":[45],"clinical":[46,137,177],"outcomes":[47],"chemotherapy":[49],"responses.":[50],"The":[51,73,97],"subtyping":[53,74],"was":[54],"an":[55,85,142],"independent":[56,86,143],"prognostic":[57,117],"factor":[58],"performed":[60],"better":[61,160],"than":[62],"current":[63,182],"tumor-node-metastasis":[64],"or":[65],"Veterans":[66],"Administration":[67],"Lung":[68],"Study":[69],"Group":[70],"staging":[71],"methods.":[72],"results":[75],"could":[76],"be":[77],"further":[78],"validated":[79,152],"using":[80],"FFPE":[81],"biopsy":[82,95],"from":[84,108],"cohort,":[87],"extending":[88],"the":[89,100,115,153,156,173,181],"analysis":[90,140],"to":[91,121,179],"both":[92],"samples.":[96],"signatures":[98],"S-II":[101,157],"subtype":[102],"in":[103,113],"particular":[104],"suggested":[105],"potential":[106,123],"benefits":[107],"immunotherapy.":[109,168],"Differentially":[110],"overexpressed":[111],"proteins":[112],"S-III,":[114],"worst":[116],"subtype,":[118],"allowed":[119],"us":[120],"nominate":[122],"targets,":[125],"indicating":[126],"that":[127,155],"patient":[128],"selection":[129],"may":[130],"bring":[131],"new":[132],"hope":[133],"for":[134,175,184],"previously":[135],"failed":[136],"trials.":[138],"Finally,":[139],"cohort":[144],"patients":[147,158],"who":[148],"had":[149,159],"received":[150],"immunotherapy":[151],"progression-free":[161],"survival":[162,165],"overall":[164],"after":[166],"first-line":[167],"Collectively,":[169],"our":[170],"study":[171],"provides":[172],"rationale":[174],"future":[176],"investigations":[178],"validate":[180],"findings":[183],"more":[185],"accurate":[186],"precise":[190],"treatments.":[191]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}