{"id":"https://openalex.org/W4392637479","doi":"https://doi.org/10.1093/gpbjnl/qzae024","title":"Chasing Sequencing Perfection: Marching Toward Higher Accuracy and Lower Costs","display_name":"Chasing Sequencing Perfection: Marching Toward Higher Accuracy and Lower Costs","publication_year":2024,"publication_date":"2024-03-11","ids":{"openalex":"https://openalex.org/W4392637479","doi":"https://doi.org/10.1093/gpbjnl/qzae024","pmid":"https://pubmed.ncbi.nlm.nih.gov/38991976"},"language":"en","primary_location":{"id":"doi:10.1093/gpbjnl/qzae024","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gpbjnl/qzae024","pdf_url":"https://academic.oup.com/gpb/advance-article-pdf/doi/10.1093/gpbjnl/qzae024/56926565/qzae024.pdf","source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/gpb/advance-article-pdf/doi/10.1093/gpbjnl/qzae024/56926565/qzae024.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048732706","display_name":"Hangxing Jia","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210167311","display_name":"Institute of Zoology","ror":"https://ror.org/05skxkv18","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311"]},{"id":"https://openalex.org/I4391768252","display_name":"State Key Laboratory of Integrated Management of Pest Insects and Rodents","ror":"https://ror.org/0528q3r27","country_code":null,"type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391768252"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hangxing Jia","raw_affiliation_strings":["CAS Key Laboratory of Zoological Systematics and Evolution & State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences , Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Zoological Systematics and Evolution & State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences , Beijing 100101, China","institution_ids":["https://openalex.org/I4210167311","https://openalex.org/I19820366","https://openalex.org/I4391768252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101911731","display_name":"Shengjun Tan","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210167311","display_name":"Institute of Zoology","ror":"https://ror.org/05skxkv18","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311"]},{"id":"https://openalex.org/I4391768252","display_name":"State Key Laboratory of Integrated Management of Pest Insects and Rodents","ror":"https://ror.org/0528q3r27","country_code":null,"type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391768252"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengjun Tan","raw_affiliation_strings":["CAS Key Laboratory of Zoological Systematics and Evolution & State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences , Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Zoological Systematics and Evolution & State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences , Beijing 100101, China","institution_ids":["https://openalex.org/I4210167311","https://openalex.org/I19820366","https://openalex.org/I4391768252"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077864427","display_name":"Yong E. Zhang","orcid":"https://orcid.org/0000-0003-3770-2383"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210097554","display_name":"Center for Excellence in Brain Science and Intelligence Technology","ror":"https://ror.org/00vpwhm04","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210097554"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4210167311","display_name":"Institute of Zoology","ror":"https://ror.org/05skxkv18","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311"]},{"id":"https://openalex.org/I4391768252","display_name":"State Key Laboratory of Integrated Management of Pest Insects and Rodents","ror":"https://ror.org/0528q3r27","country_code":null,"type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391768252"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong E Zhang","raw_affiliation_strings":["CAS Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences , Kunming 650223, China","CAS Key Laboratory of Zoological Systematics and Evolution & State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences , Beijing 100101, China","University of Chinese Academy of Sciences , Beijing 100049, China"],"affiliations":[{"raw_affiliation_string":"CAS Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences , Kunming 650223, China","institution_ids":["https://openalex.org/I4210097554","https://openalex.org/I19820366"]},{"raw_affiliation_string":"CAS Key Laboratory of Zoological Systematics and Evolution & State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences , Beijing 100101, China","institution_ids":["https://openalex.org/I4210167311","https://openalex.org/I19820366","https://openalex.org/I4391768252"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , Beijing 100049, China","institution_ids":["https://openalex.org/I4210165038"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5048732706"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210167311","https://openalex.org/I4391768252"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":2.5091,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.89163416,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"22","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9905999898910522,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9879999756813049,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5790280699729919},{"id":"https://openalex.org/keywords/dna-sequencing","display_name":"DNA sequencing","score":0.5026187896728516},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.44790148735046387},{"id":"https://openalex.org/keywords/deep-sequencing","display_name":"Deep sequencing","score":0.44159069657325745},{"id":"https://openalex.org/keywords/fidelity","display_name":"Fidelity","score":0.43192508816719055},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3578835129737854},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3351289927959442},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.29809653759002686},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1731416881084442},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.13657477498054504}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5790280699729919},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.5026187896728516},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.44790148735046387},{"id":"https://openalex.org/C132917006","wikidata":"https://www.wikidata.org/wiki/Q5250436","display_name":"Deep sequencing","level":4,"score":0.44159069657325745},{"id":"https://openalex.org/C2776459999","wikidata":"https://www.wikidata.org/wiki/Q2119376","display_name":"Fidelity","level":2,"score":0.43192508816719055},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3578835129737854},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3351289927959442},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29809653759002686},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1731416881084442},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.13657477498054504},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/gpbjnl/qzae024","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gpbjnl/qzae024","pdf_url":"https://academic.oup.com/gpb/advance-article-pdf/doi/10.1093/gpbjnl/qzae024/56926565/qzae024.pdf","source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},{"id":"pmid:38991976","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38991976","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, proteomics & bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11423848","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11423848","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11423848/pdf/qzae024.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Genomics Proteomics Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/gpbjnl/qzae024","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gpbjnl/qzae024","pdf_url":"https://academic.oup.com/gpb/advance-article-pdf/doi/10.1093/gpbjnl/qzae024/56926565/qzae024.pdf","source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3085993365","display_name":null,"funder_award_id":"(Grant No.","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3495133333","display_name":null,"funder_award_id":"XDPB17","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"},{"id":"https://openalex.org/G391238517","display_name":null,"funder_award_id":", and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5355933186","display_name":null,"funder_award_id":"31970565","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6258415954","display_name":null,"funder_award_id":"Chinese","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6913859557","display_name":null,"funder_award_id":"ZDBS-LY-SM005","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"},{"id":"https://openalex.org/G7726157001","display_name":null,"funder_award_id":"Grant No.","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8643175780","display_name":null,"funder_award_id":"2019YFA0802600","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321133","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4392637479.pdf"},"referenced_works_count":79,"referenced_works":["https://openalex.org/W1841351562","https://openalex.org/W1953000621","https://openalex.org/W1957977360","https://openalex.org/W1982224349","https://openalex.org/W1983426138","https://openalex.org/W2006721438","https://openalex.org/W2009783955","https://openalex.org/W2016966302","https://openalex.org/W2041677964","https://openalex.org/W2061680337","https://openalex.org/W2067793681","https://openalex.org/W2087464200","https://openalex.org/W2090983756","https://openalex.org/W2092772380","https://openalex.org/W2098131178","https://openalex.org/W2105368763","https://openalex.org/W2105835713","https://openalex.org/W2107356675","https://openalex.org/W2114532236","https://openalex.org/W2119923823","https://openalex.org/W2121016876","https://openalex.org/W2143197030","https://openalex.org/W2152241467","https://openalex.org/W2160225487","https://openalex.org/W2195724570","https://openalex.org/W2232214289","https://openalex.org/W2295828257","https://openalex.org/W2346663063","https://openalex.org/W2510475044","https://openalex.org/W2547511573","https://openalex.org/W2559325775","https://openalex.org/W2569995699","https://openalex.org/W2605512081","https://openalex.org/W2618082786","https://openalex.org/W2774072836","https://openalex.org/W2792407191","https://openalex.org/W2793465614","https://openalex.org/W2884441543","https://openalex.org/W2888193242","https://openalex.org/W2891014523","https://openalex.org/W2940391028","https://openalex.org/W2952746993","https://openalex.org/W2968499116","https://openalex.org/W2969552540","https://openalex.org/W3033870872","https://openalex.org/W3039458194","https://openalex.org/W3046342249","https://openalex.org/W3120817351","https://openalex.org/W3124466221","https://openalex.org/W3129532547","https://openalex.org/W3135065548","https://openalex.org/W3148807116","https://openalex.org/W3158308213","https://openalex.org/W3166693923","https://openalex.org/W3177325667","https://openalex.org/W3192707278","https://openalex.org/W3194049481","https://openalex.org/W3213101281","https://openalex.org/W4206841526","https://openalex.org/W4220994372","https://openalex.org/W4223544418","https://openalex.org/W4224289146","https://openalex.org/W4226453246","https://openalex.org/W4281715053","https://openalex.org/W4283809266","https://openalex.org/W4285077392","https://openalex.org/W4294052020","https://openalex.org/W4315490664","https://openalex.org/W4315707327","https://openalex.org/W4317553434","https://openalex.org/W4323568111","https://openalex.org/W4367294691","https://openalex.org/W4378212282","https://openalex.org/W4381716795","https://openalex.org/W4399567425","https://openalex.org/W6810582296","https://openalex.org/W6838862214","https://openalex.org/W6842429251","https://openalex.org/W6850191004"],"related_works":["https://openalex.org/W3132115146","https://openalex.org/W1969673184","https://openalex.org/W2947266077","https://openalex.org/W2619166255","https://openalex.org/W1539994441","https://openalex.org/W2472738690","https://openalex.org/W3011303654","https://openalex.org/W2359210733","https://openalex.org/W1970342753","https://openalex.org/W3089600567"],"abstract_inverted_index":{"Next-generation":[0],"sequencing":[1,19,50,107],"(NGS),":[2],"represented":[3],"by":[4],"Illumina":[5],"platforms,":[6],"has":[7],"been":[8],"an":[9],"essential":[10],"cornerstone":[11],"of":[12,22],"basic":[13],"and":[14,64,90,134],"applied":[15],"research.":[16],"However,":[17],"the":[18,48,54,65,86],"error":[20,110],"rate":[21],"1":[23],"per":[24],"1000":[25],"bp":[26],"(10-3)":[27],"represents":[28],"a":[29,75],"serious":[30],"hurdle":[31],"for":[32],"research":[33],"areas":[34],"focusing":[35],"on":[36],"rare":[37],"mutations,":[38],"such":[39],"as":[40],"somatic":[41],"mosaicism":[42],"or":[43,124],"microbe":[44],"heterogeneity.":[45],"By":[46],"examining":[47],"high-fidelity":[49],"methods":[51,83],"developed":[52],"in":[53,131],"past":[55],"decade,":[56],"we":[57,114],"summarized":[58],"three":[59,92],"major":[60],"factors":[61],"underlying":[62],"errors":[63],"corresponding":[66,87],"12":[67],"strategies":[68,89],"mitigating":[69],"these":[70],"errors.":[71],"We":[72,99],"then":[73],"proposed":[74],"novel":[76],"framework":[77],"to":[78,85,104],"classify":[79],"11":[80],"preexisting":[81],"representative":[82],"according":[84],"combinatory":[88],"identified":[91],"trends":[93],"that":[94,120],"emerged":[95],"during":[96],"methodological":[97],"developments.":[98],"further":[100],"extended":[101],"this":[102],"analysis":[103],"eight":[105],"long-read":[106,135],"methods,":[108],"emphasizing":[109],"reduction":[111],"strategies.":[112],"Finally,":[113],"suggest":[115],"two":[116],"promising":[117],"future":[118],"directions":[119],"could":[121],"achieve":[122],"comparable":[123],"even":[125],"higher":[126],"accuracy":[127],"with":[128],"lower":[129],"costs":[130],"both":[132],"NGS":[133],"sequencing.":[136]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":2}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}