{"id":"https://openalex.org/W3004798288","doi":"https://doi.org/10.1093/database/baz117","title":"Variation benchmark datasets: update, criteria, quality and applications","display_name":"Variation benchmark datasets: update, criteria, quality and applications","publication_year":2019,"publication_date":"2019-09-04","ids":{"openalex":"https://openalex.org/W3004798288","doi":"https://doi.org/10.1093/database/baz117","mag":"3004798288","pmid":"https://pubmed.ncbi.nlm.nih.gov/32016318"},"language":"en","primary_location":{"id":"doi:10.1093/database/baz117","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz117","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz117/32322837/baz117.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz117/32322837/baz117.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009043386","display_name":"Anasua Sarkar","orcid":"https://orcid.org/0000-0001-7365-3924"},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anasua Sarkar","raw_affiliation_strings":["Department of Experimental Medical Science, BMC B13, Lund University, SE-22 184 Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medical Science, BMC B13, Lund University, SE-22 184 Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100397513","display_name":"Yang Yang","orcid":"https://orcid.org/0000-0002-1290-6665"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Yang","raw_affiliation_strings":["Provincial Key Laboratory for Computer Information Processing Technology, No1. Shizi Street, Soochow University, Suzhou, 215006 Jiangsu, China","School of Computer Science and Technology, Soochow University, No1. Shizi Street, Suzhou, 215006 Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Provincial Key Laboratory for Computer Information Processing Technology, No1. Shizi Street, Soochow University, Suzhou, 215006 Jiangsu, China","institution_ids":["https://openalex.org/I3923682"]},{"raw_affiliation_string":"School of Computer Science and Technology, Soochow University, No1. Shizi Street, Suzhou, 215006 Jiangsu, China","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020878971","display_name":"Mauno Vihinen","orcid":"https://orcid.org/0000-0002-9614-7976"},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Mauno Vihinen","raw_affiliation_strings":["Department of Experimental Medical Science, BMC B13, Lund University, SE-22 184 Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medical Science, BMC B13, Lund University, SE-22 184 Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5020878971"],"corresponding_institution_ids":["https://openalex.org/I187531555"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":2.0506,"has_fulltext":true,"cited_by_count":52,"citation_normalized_percentile":{"value":0.87818834,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"2020","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9750000238418579,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9750000238418579,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9571999907493591,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.9537000060081482,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/variation","display_name":"Variation (astronomy)","score":0.8194563388824463},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.8176316618919373},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6820012927055359},{"id":"https://openalex.org/keywords/quality","display_name":"Quality (philosophy)","score":0.5393384099006653},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5384810566902161},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.5073906779289246},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3535439372062683},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.09003862738609314},{"id":"https://openalex.org/keywords/cartography","display_name":"Cartography","score":0.08164361119270325}],"concepts":[{"id":"https://openalex.org/C2778334786","wikidata":"https://www.wikidata.org/wiki/Q1586270","display_name":"Variation (astronomy)","level":2,"score":0.8194563388824463},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.8176316618919373},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6820012927055359},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.5393384099006653},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5384810566902161},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.5073906779289246},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3535439372062683},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.09003862738609314},{"id":"https://openalex.org/C58640448","wikidata":"https://www.wikidata.org/wiki/Q42515","display_name":"Cartography","level":1,"score":0.08164361119270325},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C44870925","wikidata":"https://www.wikidata.org/wiki/Q37547","display_name":"Astrophysics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D033181","descriptor_name":"Information Dissemination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D033181","descriptor_name":"Information Dissemination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D033181","descriptor_name":"Information Dissemination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/database/baz117","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz117","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz117/32322837/baz117.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:32016318","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32016318","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:lup.lub.lu.se:07bafb66-7c04-4eda-b83d-de7b93c83fef","is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/07bafb66-7c04-4eda-b83d-de7b93c83fef","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1758-0463","raw_type":"text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6997940","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6997940","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Database (Oxford)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/database/baz117","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz117","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz117/32322837/baz117.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","display_name":"Affordable and clean energy","score":0.6399999856948853}],"awards":[{"id":"https://openalex.org/G2139610729","display_name":null,"funder_award_id":"CAN 2017/699","funder_id":"https://openalex.org/F4320321491","funder_display_name":"Cancerfonden"},{"id":"https://openalex.org/G4101490082","display_name":null,"funder_award_id":"VR 2015-02510","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G6223480252","display_name":null,"funder_award_id":"61602332","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7781804812","display_name":null,"funder_award_id":"2015-02510","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321491","display_name":"Cancerfonden","ror":"https://ror.org/0527jb766"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3004798288.pdf","grobid_xml":"https://content.openalex.org/works/W3004798288.grobid-xml"},"referenced_works_count":148,"referenced_works":["https://openalex.org/W1488502645","https://openalex.org/W1504730632","https://openalex.org/W1892729224","https://openalex.org/W1965170928","https://openalex.org/W1966844407","https://openalex.org/W1970413157","https://openalex.org/W1975196485","https://openalex.org/W1976932547","https://openalex.org/W1990687284","https://openalex.org/W1992880766","https://openalex.org/W2010650881","https://openalex.org/W2011582941","https://openalex.org/W2012427806","https://openalex.org/W2013639985","https://openalex.org/W2016389191","https://openalex.org/W2017818880","https://openalex.org/W2031553026","https://openalex.org/W2035550428","https://openalex.org/W2037458235","https://openalex.org/W2051351981","https://openalex.org/W2051978340","https://openalex.org/W2058487877","https://openalex.org/W2062056791","https://openalex.org/W2063714349","https://openalex.org/W2068174058","https://openalex.org/W2069197202","https://openalex.org/W2071391537","https://openalex.org/W2083422935","https://openalex.org/W2086204383","https://openalex.org/W2092198991","https://openalex.org/W2092810439","https://openalex.org/W2093847279","https://openalex.org/W2095227542","https://openalex.org/W2096777589","https://openalex.org/W2099524123","https://openalex.org/W2099672241","https://openalex.org/W2103459989","https://openalex.org/W2103857869","https://openalex.org/W2110139885","https://openalex.org/W2110686214","https://openalex.org/W2114394955","https://openalex.org/W2117856964","https://openalex.org/W2119013806","https://openalex.org/W2119338364","https://openalex.org/W2120949690","https://openalex.org/W2122732537","https://openalex.org/W2123623399","https://openalex.org/W2124333636","https://openalex.org/W2126209963","https://openalex.org/W2129952088","https://openalex.org/W2131713299","https://openalex.org/W2132123037","https://openalex.org/W2132312350","https://openalex.org/W2134091971","https://openalex.org/W2134488721","https://openalex.org/W2135503340","https://openalex.org/W2136513422","https://openalex.org/W2142964334","https://openalex.org/W2146841526","https://openalex.org/W2148105023","https://openalex.org/W2148152877","https://openalex.org/W2150192011","https://openalex.org/W2151529283","https://openalex.org/W2153457180","https://openalex.org/W2156799643","https://openalex.org/W2161162779","https://openalex.org/W2161668835","https://openalex.org/W2164972512","https://openalex.org/W2168533552","https://openalex.org/W2168749685","https://openalex.org/W2169767349","https://openalex.org/W2185628700","https://openalex.org/W2253225498","https://openalex.org/W2262896633","https://openalex.org/W2288875731","https://openalex.org/W2291519981","https://openalex.org/W2298358682","https://openalex.org/W2302501749","https://openalex.org/W2310980987","https://openalex.org/W2329374371","https://openalex.org/W2331972180","https://openalex.org/W2388427680","https://openalex.org/W2399001116","https://openalex.org/W2403357649","https://openalex.org/W2406197031","https://openalex.org/W2428593791","https://openalex.org/W2466594255","https://openalex.org/W2499881264","https://openalex.org/W2510298658","https://openalex.org/W2526413677","https://openalex.org/W2528949833","https://openalex.org/W2537556928","https://openalex.org/W2553032175","https://openalex.org/W2566395839","https://openalex.org/W2569442665","https://openalex.org/W2590680504","https://openalex.org/W2611549356","https://openalex.org/W2612969216","https://openalex.org/W2614443510","https://openalex.org/W2661779417","https://openalex.org/W2734861826","https://openalex.org/W2742200403","https://openalex.org/W2742600815","https://openalex.org/W2744079488","https://openalex.org/W2748660142","https://openalex.org/W2770473264","https://openalex.org/W2773787581","https://openalex.org/W2780523853","https://openalex.org/W2784070577","https://openalex.org/W2788439305","https://openalex.org/W2790516087","https://openalex.org/W2794373321","https://openalex.org/W2794503008","https://openalex.org/W2794541436","https://openalex.org/W2796386151","https://openalex.org/W2802948002","https://openalex.org/W2803713584","https://openalex.org/W2806151064","https://openalex.org/W2806311302","https://openalex.org/W2883631445","https://openalex.org/W2889924837","https://openalex.org/W2891403781","https://openalex.org/W2892250187","https://openalex.org/W2903344416","https://openalex.org/W2905037503","https://openalex.org/W2905130244","https://openalex.org/W2911855146","https://openalex.org/W2915667579","https://openalex.org/W2922387607","https://openalex.org/W2949886398","https://openalex.org/W2951804872","https://openalex.org/W2953103783","https://openalex.org/W2953301805","https://openalex.org/W2953328427","https://openalex.org/W2953374171","https://openalex.org/W2956180888","https://openalex.org/W2961258159","https://openalex.org/W4210267605","https://openalex.org/W6648400570","https://openalex.org/W6654904804","https://openalex.org/W6667435067","https://openalex.org/W6731467534","https://openalex.org/W6738337739","https://openalex.org/W6749923601","https://openalex.org/W6751508916","https://openalex.org/W6752065168","https://openalex.org/W6755198985","https://openalex.org/W6764477456"],"related_works":["https://openalex.org/W2386430105","https://openalex.org/W2356521405","https://openalex.org/W2378211422","https://openalex.org/W4321353415","https://openalex.org/W2745001401","https://openalex.org/W2038534795","https://openalex.org/W2130974462","https://openalex.org/W2384358604","https://openalex.org/W2028665553","https://openalex.org/W2086519370"],"abstract_inverted_index":{"Development":[0],"of":[1,85,110,123,236,241,252,278],"new":[2,95,237],"computational":[3],"methods":[4,238],"and":[5,35,45,50,56,79,87,143,150,155,161,172,181,190,212,214,226,234,239,261,268,281],"testing":[6,235],"their":[7,88],"performance":[8,25,251],"has":[9],"to":[10,20,53,244,257,276],"be":[11,26,47,273],"carried":[12],"out":[13],"using":[14],"experimental":[15],"data.":[16,283],"Only":[17],"in":[18,130,153],"comparison":[19,240],"existing":[21,61],"knowledge":[22],"can":[23],"method":[24],"assessed.":[27],"For":[28],"that":[29,263],"purpose,":[30],"benchmark":[31,41,66,259],"datasets":[32,42,67,96,125,136,147,165,187],"with":[33,93],"known":[34],"verified":[36],"outcome":[37],"are":[38,43,58,146,185,203,266],"needed.":[39],"High-quality":[40],"valuable":[44],"may":[46,272],"difficult,":[48],"laborious":[49],"time":[51],"consuming":[52],"generate.":[54],"VariBench":[55,90,115,231],"VariSNP":[57],"the":[59,113,124,131,218,250,253],"two":[60],"databases":[62],"for":[63,70,77,82,148,175,188,198],"sharing":[64],"variation":[65,71,199],"used":[68,76],"mainly":[69],"interpretation.":[72],"They":[73],"have":[74,137],"been":[75,138],"training":[78],"benchmarking":[80],"predictors":[81],"various":[83],"types":[84],"variations":[86],"effects.":[89,201],"was":[91],"updated":[92,230],"419":[94],"from":[97],"109":[98],"papers":[99],"containing":[100],"altogether":[101],"329":[102],"014":[103],"152":[104],"variants;":[105],"however,":[106,270],"there":[107,184,271],"is":[108,116],"plenty":[109],"redundancy":[111],"between":[112],"datasets.":[114],"freely":[117],"available":[118,135],"at":[119,206,217],"http://structure.bmc.lu.se/VariBench/.":[120],"The":[121,134,229],"contents":[122],"vary":[126],"depending":[127],"on":[128],"information":[129],"original":[132],"source.":[133],"categorized":[139],"into":[140],"20":[141],"groups":[142],"subgroups.":[144],"There":[145],"insertions":[149],"deletions,":[151],"substitutions":[152],"coding":[154],"non-coding":[156],"region,":[157],"structure":[158],"mapped,":[159],"synonymous":[160],"benign":[162],"variants.":[163],"Effect-specific":[164],"include":[166],"DNA":[167],"regulatory":[168],"elements,":[169],"RNA":[170,211],"splicing,":[171],"protein":[173,219],"property":[174],"aggregation,":[176],"binding":[177],"free":[178],"energy,":[179],"disorder":[180],"stability.":[182],"Then":[183],"several":[186,258],"molecule-specific":[189],"disease-specific":[191],"applications,":[192],"as":[193,195],"well":[194],"one":[196],"dataset":[197],"phenotype":[200],"Variants":[202],"often":[204],"described":[205],"three":[207],"molecular":[208],"levels":[209],"(DNA,":[210],"protein)":[213],"sometimes":[215],"also":[216],"structural":[220],"level":[221],"including":[222],"relevant":[223],"cross":[224],"references":[225],"variant":[227],"descriptions.":[228],"facilitates":[232],"development":[233],"obtained":[242],"performances":[243],"previously":[245],"published":[246],"methods.":[247],"We":[248],"compared":[249],"pathogenicity/tolerance":[254],"predictor":[255],"PON-P2":[256],"studies,":[260],"show":[262],"such":[264],"comparisons":[265],"feasible":[267],"useful,":[269],"limitations":[274],"due":[275],"lack":[277],"provided":[279],"details":[280],"shared":[282],"Database":[284],"URL:":[285],"http://structure.bmc.lu.se/VariBench.":[286]},"counts_by_year":[{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}