{"id":"https://openalex.org/W2992839032","doi":"https://doi.org/10.1093/database/baz115","title":"Identification of tRNA-derived ncRNAs in TCGA and NCI-60 panel cell lines and development of the public database tRFexplorer","display_name":"Identification of tRNA-derived ncRNAs in TCGA and NCI-60 panel cell lines and development of the public database tRFexplorer","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2992839032","doi":"https://doi.org/10.1093/database/baz115","mag":"2992839032","pmid":"https://pubmed.ncbi.nlm.nih.gov/31735953"},"language":"en","primary_location":{"id":"doi:10.1093/database/baz115","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz115","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz115/30858139/baz115.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz115/30858139/baz115.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056591256","display_name":"Alessandro La Ferlita","orcid":"https://orcid.org/0000-0002-3680-3177"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro La Ferlita","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy","Department of Physics and Astronomy, University of Catania, Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Physics and Astronomy, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023263135","display_name":"Salvatore Alaimo","orcid":"https://orcid.org/0000-0003-4825-7617"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Salvatore Alaimo","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042603520","display_name":"Dario Veneziano","orcid":null},"institutions":[{"id":"https://openalex.org/I4210145812","display_name":"Cancer Genetics (United States)","ror":"https://ror.org/05feyya22","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145812"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dario Veneziano","raw_affiliation_strings":["Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH"],"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH","institution_ids":["https://openalex.org/I4210145812","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061759967","display_name":"Giovanni Nigita","orcid":"https://orcid.org/0000-0001-8880-4334"},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I4210145812","display_name":"Cancer Genetics (United States)","ror":"https://ror.org/05feyya22","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Giovanni Nigita","raw_affiliation_strings":["Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH"],"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH","institution_ids":["https://openalex.org/I4210145812","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054316148","display_name":"Veronica Balatti","orcid":null},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I4210145812","display_name":"Cancer Genetics (United States)","ror":"https://ror.org/05feyya22","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Veronica Balatti","raw_affiliation_strings":["Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH"],"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH","institution_ids":["https://openalex.org/I4210145812","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079700663","display_name":"Carlo M. Croce","orcid":"https://orcid.org/0000-0003-3788-1457"},"institutions":[{"id":"https://openalex.org/I4210145812","display_name":"Cancer Genetics (United States)","ror":"https://ror.org/05feyya22","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145812"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlo M Croce","raw_affiliation_strings":["Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH"],"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH","institution_ids":["https://openalex.org/I4210145812","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000272110","display_name":"Alfredo Ferro","orcid":"https://orcid.org/0000-0002-9431-5788"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alfredo Ferro","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057481978","display_name":"Alfredo Pulvirenti","orcid":"https://orcid.org/0000-0002-9764-0295"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Alfredo Pulvirenti","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5057481978"],"corresponding_institution_ids":["https://openalex.org/I39063666"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":2.4889,"has_fulltext":true,"cited_by_count":58,"citation_normalized_percentile":{"value":0.90276806,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"2019","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transfer-rna","display_name":"Transfer RNA","score":0.7743616700172424},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.672418475151062},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.5740846395492554},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5714852213859558},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5251145958900452},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.5182521343231201},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.501380205154419},{"id":"https://openalex.org/keywords/non-coding-rna","display_name":"Non-coding RNA","score":0.4680955708026886},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.43641233444213867},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.41040894389152527},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.06940528750419617}],"concepts":[{"id":"https://openalex.org/C153957851","wikidata":"https://www.wikidata.org/wiki/Q201448","display_name":"Transfer RNA","level":4,"score":0.7743616700172424},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.672418475151062},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.5740846395492554},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5714852213859558},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5251145958900452},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.5182521343231201},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.501380205154419},{"id":"https://openalex.org/C194993378","wikidata":"https://www.wikidata.org/wiki/Q427087","display_name":"Non-coding RNA","level":4,"score":0.4680955708026886},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.43641233444213867},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.41040894389152527},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.06940528750419617}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012343","descriptor_name":"RNA, Transfer","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012343","descriptor_name":"RNA, Transfer","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012343","descriptor_name":"RNA, Transfer","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/database/baz115","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz115","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz115/30858139/baz115.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:31735953","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31735953","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:6859256","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6859256","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Database (Oxford)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/database/baz115","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz115","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz115/30858139/baz115.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals","score":0.44999998807907104}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2992839032.pdf","grobid_xml":"https://content.openalex.org/works/W2992839032.grobid-xml"},"referenced_works_count":67,"referenced_works":["https://openalex.org/W1528304019","https://openalex.org/W1832445447","https://openalex.org/W1966116114","https://openalex.org/W1992014004","https://openalex.org/W1995387163","https://openalex.org/W2003624918","https://openalex.org/W2020408643","https://openalex.org/W2026566929","https://openalex.org/W2033571727","https://openalex.org/W2036897871","https://openalex.org/W2075292896","https://openalex.org/W2087312216","https://openalex.org/W2087463572","https://openalex.org/W2100966665","https://openalex.org/W2103196126","https://openalex.org/W2106039274","https://openalex.org/W2117147211","https://openalex.org/W2128032802","https://openalex.org/W2134526812","https://openalex.org/W2140729960","https://openalex.org/W2141384633","https://openalex.org/W2142584500","https://openalex.org/W2145067337","https://openalex.org/W2146512944","https://openalex.org/W2154431984","https://openalex.org/W2164256634","https://openalex.org/W2164976077","https://openalex.org/W2169694864","https://openalex.org/W2172932999","https://openalex.org/W2223836536","https://openalex.org/W2287545739","https://openalex.org/W2303912045","https://openalex.org/W2321275168","https://openalex.org/W2336957559","https://openalex.org/W2338525238","https://openalex.org/W2354695783","https://openalex.org/W2415209296","https://openalex.org/W2417123930","https://openalex.org/W2510348945","https://openalex.org/W2534006293","https://openalex.org/W2558945705","https://openalex.org/W2567737075","https://openalex.org/W2589911306","https://openalex.org/W2596379844","https://openalex.org/W2605223191","https://openalex.org/W2608110242","https://openalex.org/W2711831439","https://openalex.org/W2728549768","https://openalex.org/W2734686459","https://openalex.org/W2740741519","https://openalex.org/W2744525160","https://openalex.org/W2765768951","https://openalex.org/W2769036773","https://openalex.org/W2769912973","https://openalex.org/W2793056024","https://openalex.org/W2802787795","https://openalex.org/W2802838762","https://openalex.org/W2806435205","https://openalex.org/W2888576209","https://openalex.org/W2889199113","https://openalex.org/W2890244942","https://openalex.org/W2894501980","https://openalex.org/W2950801021","https://openalex.org/W2951118605","https://openalex.org/W6700360812","https://openalex.org/W6731781087","https://openalex.org/W6753987644"],"related_works":["https://openalex.org/W2040216736","https://openalex.org/W2012158738","https://openalex.org/W1998434095","https://openalex.org/W2737319532","https://openalex.org/W1979806605","https://openalex.org/W2058984380","https://openalex.org/W2900182103","https://openalex.org/W1988125422","https://openalex.org/W4365136234","https://openalex.org/W3183769948"],"abstract_inverted_index":{"Next-generation":[0],"sequencing":[1],"is":[2],"increasing":[3],"our":[4],"understanding":[5],"and":[6,18,24,94,121,202,206,217],"knowledge":[7],"of":[8,133,142,158,186,196,239],"non-coding":[9],"RNAs":[10,91,98],"(ncRNAs),":[11],"elucidating":[12],"their":[13,59,233],"roles":[14,236],"in":[15,40,54,62,79,82,114,162,166,189,200,209,212,237],"molecular":[16],"mechanisms":[17],"processes":[19],"such":[20,27,187],"as":[21,168,170,191,193],"cell":[22,164],"growth":[23],"development.":[25],"Within":[26],"a":[28,147],"class,":[29],"tRNA-derived":[30,52,77,83,89,111,134,160,197],"ncRNAs":[31,53,78,112,135,161,198],"have":[32],"been":[33],"recently":[34],"associated":[35],"with":[36,154,204,214],"gene":[37,205],"expression":[38,60,156,184,199,208],"regulation":[39],"cancer":[41],"progression.":[42],"In":[43,102],"this":[44],"paper,":[45],"we":[46,57,104],"characterize,":[47],"for":[48,171],"the":[49,138,155,177,225],"first":[50],"time,":[51],"NCI-60.":[55],"Furthermore,":[56],"assess":[58],"profile":[61,157],"The":[63],"Cancer":[64],"Genome":[65],"Atlas":[66],"(TCGA).":[67],"Our":[68],"comprehensive":[69],"analysis":[70],"allowed":[71],"us":[72,180],"to":[73,107,181,231],"report":[74],"322":[75],"distinct":[76,110],"NCI-60,":[80],"categorized":[81,113],"fragments":[84,188],"(11":[85],"tRF-5s,":[86,116],"55":[87],"tRF-3s),":[88],"small":[90],"(107":[92],"tsRNAs)":[93],"tRNA":[95],"5'":[96,123,139],"leader":[97,124,140],"(149":[99],"sequences":[100],"identified).":[101],"TCGA,":[103,190],"were":[105],"able":[106],"identify":[108],"232":[109],"53":[115],"58":[117,122],"tRF-3s,":[118],"63":[119],"tsRNAs":[120],"RNAs.":[125],"This":[126],"latter":[127],"group":[128],"represents":[129],"an":[130,228],"additional":[131],"evidence":[132],"originating":[136],"from":[137],"region":[141],"precursor":[143],"tRNA.":[144],"We":[145],"developed":[146],"public":[148],"database,":[149],"tRFexplorer,":[150],"which":[151],"provides":[152,227],"users":[153],"each":[159,172],"every":[163],"line":[165],"NCI-60":[167,203],"well":[169,192],"TCGA":[173,201,210],"tumor":[174],"type.":[175],"Moreover,":[176],"system":[178],"allows":[179],"perform":[182],"differential":[183],"analyses":[185,195],"correlation":[194],"miRNA":[207],"samples,":[211],"association":[213],"all":[215],"omics":[216],"compound":[218],"activities":[219],"data":[220],"available":[221],"on":[222],"CellMiner.":[223],"Hence,":[224],"tool":[226],"important":[229],"opportunity":[230],"investigate":[232],"potential":[234],"biological":[235],"absence":[238],"any":[240],"direct":[241],"experimental":[242],"evidence.":[243],"Database":[244],"URL:":[245],"https://trfexplorer.cloud/.":[246]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":9}],"updated_date":"2026-03-07T16:01:11.037858","created_date":"2025-10-10T00:00:00"}
