{"id":"https://openalex.org/W2954571587","doi":"https://doi.org/10.1093/database/baz060","title":"ResMarkerDB: a database of biomarkers of response to antibody therapy in breast and colorectal cancer","display_name":"ResMarkerDB: a database of biomarkers of response to antibody therapy in breast and colorectal cancer","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2954571587","doi":"https://doi.org/10.1093/database/baz060","mag":"2954571587","pmid":"https://pubmed.ncbi.nlm.nih.gov/31169290"},"language":"en","primary_location":{"id":"doi:10.1093/database/baz060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz060","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz060/28762485/baz060.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz060/28762485/baz060.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033811228","display_name":"Judith P\u00e9rez\u2010Granado","orcid":"https://orcid.org/0000-0002-4098-3000"},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Pompeu Fabra University","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]},{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I4210136145","display_name":"Municipal Institute for Medical Research","ror":"https://ror.org/039evc422","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210136145"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Judith P\u00e9rez-Granado","raw_affiliation_strings":["Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University), Dr. Aiguader, Barcelona, Spain","Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University),\nDr. Aiguader, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University), Dr. Aiguader, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210156109","https://openalex.org/I4210136145"]},{"raw_affiliation_string":"Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University),\nDr. Aiguader, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210156109","https://openalex.org/I4210136145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054199754","display_name":"Janet Pi\u00f1ero","orcid":"https://orcid.org/0000-0003-1244-7654"},"institutions":[{"id":"https://openalex.org/I4210136145","display_name":"Municipal Institute for Medical Research","ror":"https://ror.org/039evc422","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210136145"]},{"id":"https://openalex.org/I170486558","display_name":"Pompeu Fabra University","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]},{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Janet Pi\u00f1ero","raw_affiliation_strings":["Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University), Dr. Aiguader, Barcelona, Spain","Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University),\nDr. Aiguader, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University), Dr. Aiguader, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210156109","https://openalex.org/I4210136145"]},{"raw_affiliation_string":"Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University),\nDr. Aiguader, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210156109","https://openalex.org/I4210136145"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028427590","display_name":"Laura I. Furlong","orcid":"https://orcid.org/0000-0002-9383-528X"},"institutions":[{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I170486558","display_name":"Pompeu Fabra University","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]},{"id":"https://openalex.org/I4210136145","display_name":"Municipal Institute for Medical Research","ror":"https://ror.org/039evc422","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210136145"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Laura I Furlong","raw_affiliation_strings":["Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University), Dr. Aiguader, Barcelona, Spain","Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University),\nDr. Aiguader, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University), Dr. Aiguader, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210156109","https://openalex.org/I4210136145"]},{"raw_affiliation_string":"Research Programme on Biomedical Informatics (GRIB), IMIM (Hospital del Mar Medical Research Institute), UPF (Pompeu Fabra University),\nDr. Aiguader, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210156109","https://openalex.org/I4210136145"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5028427590"],"corresponding_institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210136145","https://openalex.org/I4210156109"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":1.5363,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.82904239,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"2019","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.6560475826263428},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.6471127271652222},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6160350441932678},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"Colorectal cancer","score":0.6108413934707642},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.5588847398757935},{"id":"https://openalex.org/keywords/biomarker-discovery","display_name":"Biomarker discovery","score":0.5587126612663269},{"id":"https://openalex.org/keywords/drug-response","display_name":"Drug response","score":0.46401652693748474},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.453901469707489},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.4181568920612335},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.38732457160949707},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.37576305866241455},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.3319218158721924},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3211291432380676},{"id":"https://openalex.org/keywords/proteomics","display_name":"Proteomics","score":0.13340142369270325},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12917417287826538},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.0818752646446228},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.07892987132072449}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6560475826263428},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6471127271652222},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6160350441932678},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6108413934707642},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5588847398757935},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.5587126612663269},{"id":"https://openalex.org/C2994119904","wikidata":"https://www.wikidata.org/wiki/Q1251001","display_name":"Drug response","level":3,"score":0.46401652693748474},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.453901469707489},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4181568920612335},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.38732457160949707},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.37576305866241455},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.3319218158721924},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3211291432380676},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.13340142369270325},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12917417287826538},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0818752646446228},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07892987132072449},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000912","descriptor_name":"Antibodies, Neoplasm","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000912","descriptor_name":"Antibodies, Neoplasm","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000912","descriptor_name":"Antibodies, Neoplasm","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/database/baz060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz060","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz060/28762485/baz060.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:31169290","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31169290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:repositori.upf.edu:10230/43043","is_oa":true,"landing_page_url":"http://hdl.handle.net/10230/43043","pdf_url":null,"source":{"id":"https://openalex.org/S4306402615","display_name":"Repositori digital de la UPF (Universitat Pompeu Fabra)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I170486558","host_organization_name":"Universitat Pompeu Fabra","host_organization_lineage":["https://openalex.org/I170486558"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6551372","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6551372","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Database (Oxford)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/database/baz060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz060","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baz060/28762485/baz060.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5099999904632568}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2954571587.pdf","grobid_xml":"https://content.openalex.org/works/W2954571587.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1964670939","https://openalex.org/W1980183403","https://openalex.org/W2096525273","https://openalex.org/W2098352219","https://openalex.org/W2106465830","https://openalex.org/W2117692326","https://openalex.org/W2124045889","https://openalex.org/W2148181778","https://openalex.org/W2159583324","https://openalex.org/W2230320310","https://openalex.org/W2262414037","https://openalex.org/W2280793526","https://openalex.org/W2286693725","https://openalex.org/W2523486962","https://openalex.org/W2537679995","https://openalex.org/W2551354077","https://openalex.org/W2559466477","https://openalex.org/W2583911935","https://openalex.org/W2591209097","https://openalex.org/W2604121843","https://openalex.org/W2613784923","https://openalex.org/W2747907311","https://openalex.org/W2767891136","https://openalex.org/W2791162091","https://openalex.org/W2795441251","https://openalex.org/W2796408191","https://openalex.org/W2896872272","https://openalex.org/W2949492942","https://openalex.org/W4250359879","https://openalex.org/W4251386234","https://openalex.org/W6729601386"],"related_works":["https://openalex.org/W112583468","https://openalex.org/W96119380","https://openalex.org/W4298030740","https://openalex.org/W3023706879","https://openalex.org/W4246773350","https://openalex.org/W2096326357","https://openalex.org/W2108949684","https://openalex.org/W2012655824","https://openalex.org/W1965976436","https://openalex.org/W3177170977"],"abstract_inverted_index":{"The":[0,226],"clinical":[1],"efficacy":[2],"of":[3,18,45,48,56,79,116,126,143,146,159,161,172,174,197,202,207,213,248,252,254,272],"therapeutic":[4],"monoclonal":[5],"antibodies":[6],"for":[7,82],"breast":[8,83,167,257],"and":[9,54,72,84,100,106,166,180,184,258],"colorectal":[10,85,165,259],"cancer":[11,86],"has":[12],"greatly":[13],"contributed":[14],"to":[15,26,35,102,109,113,136,139,148,223,244,263],"the":[16,43,66,137,141,187,214,246,249],"improvement":[17],"patients'":[19],"outcomes":[20],"by":[21],"individualizing":[22],"their":[23,27],"treatments":[24],"according":[25],"genomic":[28,67],"background.":[29],"However,":[30,90],"primary":[31],"or":[32],"acquired":[33],"resistance":[34],"treatment":[36,73,80,149],"reduces":[37],"its":[38],"efficacy.":[39],"In":[40],"this":[41],"context,":[42],"identification":[44,142],"biomarkers":[46,78,94,145,160,173,196,204,253,271],"predictive":[47],"drug":[49,117,162,175,224,273],"response":[50,81,118,147,163,176,222,255,274],"would":[51],"support":[52,140],"research":[53,266],"development":[55],"new":[57,181],"alternative":[58],"treatments.":[59],"Biomarkers":[60],"play":[61],"a":[62,124,133,156,241],"major":[63],"role":[64],"in":[65,119,132,150,164,221,256,268,275],"revolution,":[68],"supporting":[69],"disease":[70],"diagnosis":[71],"decision-making.":[74],"Currently,":[75],"several":[76,98],"molecular":[77],"have":[87],"been":[88],"described.":[89],"information":[91],"on":[92],"these":[93,203],"is":[95,123,211],"scattered":[96],"across":[97],"resources,":[99],"needs":[101],"be":[103,110],"identified,":[104],"collected":[105],"properly":[107],"integrated":[108],"fully":[111],"exploited":[112],"inform":[114],"monitoring":[115],"patients.":[120],"Therefore,":[121],"there":[122],"need":[125],"resources":[127,216],"that":[128],"offer":[129],"biomarker":[130],"data":[131,171,182,220],"harmonized":[134],"manner":[135],"user":[138],"actionable":[144,270],"cancer.":[151,168,260,276],"ResMarkerDB":[152,192,210,239],"was":[153],"developed":[154],"as":[155,190],"comprehensive":[157],"resource":[158],"It":[169,261],"integrates":[170],"from":[177,186],"existing":[178],"repositories,":[179],"extracted":[183],"curated":[185],"literature":[188],"(referred":[189],"ResCur).":[191],"currently":[193],"features":[194],"266":[195],"diverse":[198],"nature.":[199],"Twenty-five":[200],"percent":[201],"are":[205],"exclusive":[206],"ResMarkerDB.":[208],"Furthermore,":[209],"one":[212],"few":[215],"offering":[217],"non-coding":[218],"DNA":[219],"treatment.":[225],"database":[227],"contains":[228],"more":[229,235],"than":[230,236],"500":[231],"biomarker-drug-tumour":[232],"associations,":[233],"covering":[234],"100":[237],"genes.":[238],"provides":[240],"web":[242],"interface":[243],"facilitate":[245],"exploration":[247],"current":[250],"knowledge":[251],"aims":[262],"enhance":[264],"translational":[265],"efforts":[267],"identifying":[269]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2}],"updated_date":"2026-03-10T16:38:18.471706","created_date":"2025-10-10T00:00:00"}