{"id":"https://openalex.org/W2916995184","doi":"https://doi.org/10.1093/database/baz017","title":"A cross-source, system-agnostic solution for clinical data review","display_name":"A cross-source, system-agnostic solution for clinical data review","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2916995184","doi":"https://doi.org/10.1093/database/baz017","mag":"2916995184","pmid":"https://pubmed.ncbi.nlm.nih.gov/30773591"},"language":"en","primary_location":{"id":"doi:10.1093/database/baz017","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz017","pdf_url":null,"source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/database/baz017","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089486050","display_name":"Michael Farnum","orcid":null},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael A Farnum","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057244709","display_name":"Mathangi Ashok","orcid":null},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mathangi Ashok","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055475531","display_name":"Daniel C. Kowalski","orcid":null},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Kowalski","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030739481","display_name":"Fang Du","orcid":"https://orcid.org/0000-0002-7958-9609"},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fang Du","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069294868","display_name":"Lalit Mohanty","orcid":null},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lalit Mohanty","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036391830","display_name":"Paul Konstant","orcid":null},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Konstant","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029934655","display_name":"Joseph Ciervo","orcid":null},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph Ciervo","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044022706","display_name":"Victor S. Lobanov","orcid":"https://orcid.org/0000-0003-3557-1033"},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victor S Lobanov","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053892487","display_name":"Dimitris K. Agrafiotis","orcid":"https://orcid.org/0000-0002-5604-5692"},"institutions":[{"id":"https://openalex.org/I2801558778","display_name":"LabCorp (United States)","ror":"https://ror.org/03zsdhz84","country_code":"US","type":"company","lineage":["https://openalex.org/I2801558778"]},{"id":"https://openalex.org/I60638368","display_name":"Covance (United States)","ror":"https://ror.org/02hhsqf45","country_code":"US","type":"company","lineage":["https://openalex.org/I60638368"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dimitris K Agrafiotis","raw_affiliation_strings":["Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA"],"raw_orcid":"https://orcid.org/0000-0002-5604-5692","affiliations":[{"raw_affiliation_string":"Covance, the Drug Development Division of LabCorp, 210 Carnegie Center, Princeton, NJ, USA","institution_ids":["https://openalex.org/I60638368","https://openalex.org/I2801558778"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5089486050"],"corresponding_institution_ids":["https://openalex.org/I2801558778","https://openalex.org/I60638368"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":0.1661,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.58722853,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2019","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.9922999739646912,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8115853071212769},{"id":"https://openalex.org/keywords/automation","display_name":"Automation","score":0.5803346037864685},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.5065246820449829},{"id":"https://openalex.org/keywords/resource","display_name":"Resource (disambiguation)","score":0.4736315608024597},{"id":"https://openalex.org/keywords/data-management","display_name":"Data management","score":0.4477446675300598},{"id":"https://openalex.org/keywords/data-validation","display_name":"Data validation","score":0.4253644347190857},{"id":"https://openalex.org/keywords/missing-data","display_name":"Missing data","score":0.42255792021751404},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.38953477144241333},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.3261792063713074}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8115853071212769},{"id":"https://openalex.org/C115901376","wikidata":"https://www.wikidata.org/wiki/Q184199","display_name":"Automation","level":2,"score":0.5803346037864685},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.5065246820449829},{"id":"https://openalex.org/C206345919","wikidata":"https://www.wikidata.org/wiki/Q20380951","display_name":"Resource (disambiguation)","level":2,"score":0.4736315608024597},{"id":"https://openalex.org/C1668388","wikidata":"https://www.wikidata.org/wiki/Q1149776","display_name":"Data management","level":2,"score":0.4477446675300598},{"id":"https://openalex.org/C92446256","wikidata":"https://www.wikidata.org/wiki/Q3306762","display_name":"Data validation","level":2,"score":0.4253644347190857},{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.42255792021751404},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.38953477144241333},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.3261792063713074},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073458","descriptor_name":"Data Warehousing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073458","descriptor_name":"Data Warehousing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073458","descriptor_name":"Data Warehousing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019992","descriptor_name":"Databases as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019992","descriptor_name":"Databases as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019992","descriptor_name":"Databases as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/database/baz017","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz017","pdf_url":null,"source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:30773591","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30773591","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:europepmc.org:5368845","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6378235","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/database/baz017","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baz017","pdf_url":null,"source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4300000071525574,"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1995279104","https://openalex.org/W2009432182","https://openalex.org/W2082801347","https://openalex.org/W2394416255","https://openalex.org/W2497038045","https://openalex.org/W2522921747","https://openalex.org/W2810770579","https://openalex.org/W2920875956","https://openalex.org/W2924299834","https://openalex.org/W2934258137"],"related_works":["https://openalex.org/W4380150146","https://openalex.org/W3024870410","https://openalex.org/W2410652950","https://openalex.org/W4283773154","https://openalex.org/W3139174110","https://openalex.org/W4289597203","https://openalex.org/W2085630472","https://openalex.org/W2072940089","https://openalex.org/W2470840815","https://openalex.org/W2994207110"],"abstract_inverted_index":{"Assembly":[0],"of":[1,96,101,109,116],"complete":[2],"and":[3,12,18,30,39,45,51,71,74,81,88,103,106,120,127,132,146,153],"error-free":[4],"clinical":[5,61],"trial":[6],"data":[7,35,62,66,73,94,125],"sets":[8],"for":[9,60,129,143,150],"statistical":[10],"analysis":[11],"regulatory":[13],"submission":[14],"requires":[15],"extensive":[16,134],"effort":[17],"communication":[19],"among":[20],"investigational":[21],"sites,":[22],"central":[23],"laboratories,":[24],"pharmaceutical":[25],"sponsors,":[26],"contract":[27],"research":[28],"organizations":[29],"other":[31],"entities.":[32],"Traditionally,":[33],"this":[34],"is":[36,48],"captured,":[37],"cleaned":[38],"reconciled":[40],"through":[41],"multiple":[42],"disjointed":[43],"systems":[44],"processes,":[46],"which":[47],"resource":[49],"intensive":[50],"error":[52],"prone.":[53],"Here,":[54],"we":[55],"introduce":[56],"a":[57,78],"new":[58],"system":[59],"review":[63,100],"that":[64],"helps":[65],"managers":[67],"identify":[68],"missing,":[69],"erroneous":[70],"inconsistent":[72],"manage":[75],"queries":[76],"in":[77],"unified,":[79],"system-agnostic":[80],"efficient":[82],"way.":[83],"Our":[84],"solution":[85],"enables":[86],"timely":[87],"integrated":[89],"access":[90],"to":[91,137],"all":[92],"study":[93],"regardless":[95],"source,":[97],"facilitates":[98],"the":[99,107,110,114],"validation":[102],"discrepancy":[104],"checks":[105],"management":[108],"resulting":[111],"queries,":[112],"tracks":[113],"status":[115],"page":[117],"review,":[118],"verification":[119],"locking":[121],"activities,":[122],"monitors":[123],"subject":[124],"cleanliness":[126],"readiness":[128],"database":[130],"lock":[131],"provides":[133],"configuration":[135],"options":[136],"meet":[138],"any":[139],"study's":[140],"needs,":[141],"automation":[142],"regular":[144],"updates":[145],"fit-for-purpose":[147],"user":[148],"interfaces":[149],"global":[151],"oversight":[152],"problem":[154],"detection.":[155]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}