{"id":"https://openalex.org/W2564116841","doi":"https://doi.org/10.1093/database/baw159","title":"HEDD: the human epigenetic drug database","display_name":"HEDD: the human epigenetic drug database","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2564116841","doi":"https://doi.org/10.1093/database/baw159","mag":"2564116841","pmid":"https://pubmed.ncbi.nlm.nih.gov/28025347"},"language":"en","primary_location":{"id":"doi:10.1093/database/baw159","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baw159","pdf_url":null,"source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/database/baw159","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101398997","display_name":"Yunfeng Qi","orcid":"https://orcid.org/0000-0002-2704-6792"},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]},{"id":"https://openalex.org/I4210089756","display_name":"Bioscience (China)","ror":"https://ror.org/0072d4h61","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210089756"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yunfeng Qi","raw_affiliation_strings":["Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China qiyunfeng911@outlook.com","Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China qiyunfeng911@outlook.com","institution_ids":[]},{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348","https://openalex.org/I4210089756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053719139","display_name":"Dadong Wang","orcid":"https://orcid.org/0000-0003-0409-2259"},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dadong Wang","raw_affiliation_strings":["Department of Computer Science and Technology, Computer College, Jilin Normal University, Siping, China","Department of Social Physical Education, Physical Education College, Jilin Normal University, Siping, China","Department of Computer Science and Technology, Computer College, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Computer College, Jilin Normal University, Siping, China","institution_ids":[]},{"raw_affiliation_string":"Department of Social Physical Education, Physical Education College, Jilin Normal University, Siping, China","institution_ids":[]},{"raw_affiliation_string":"Department of Computer Science and Technology, Computer College, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030259857","display_name":"Daying Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daying Wang","raw_affiliation_strings":["Department of Computer Science and Technology, Computer College, Jilin Normal University, Siping, China","Department of Social Physical Education, Physical Education College, Jilin Normal University, Siping, China","Department of Social Physical Education, Physical Education College, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Computer College, Jilin Normal University, Siping, China","institution_ids":[]},{"raw_affiliation_string":"Department of Social Physical Education, Physical Education College, Jilin Normal University, Siping, China","institution_ids":[]},{"raw_affiliation_string":"Department of Social Physical Education, Physical Education College, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041917530","display_name":"Taicheng Jin","orcid":null},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Taicheng Jin","raw_affiliation_strings":["Department of Biotechnology, School of Life Science, Jilin Normal University, Siping, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, School of Life Science, Jilin Normal University, Siping, China","institution_ids":["https://openalex.org/I149240348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069834182","display_name":"Liping Yang","orcid":"https://orcid.org/0009-0007-7789-2632"},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]},{"id":"https://openalex.org/I4210089756","display_name":"Bioscience (China)","ror":"https://ror.org/0072d4h61","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210089756"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liping Yang","raw_affiliation_strings":["Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","institution_ids":["https://openalex.org/I149240348"]},{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348","https://openalex.org/I4210089756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103163467","display_name":"Hui Wu","orcid":"https://orcid.org/0009-0003-5966-3570"},"institutions":[{"id":"https://openalex.org/I4210089756","display_name":"Bioscience (China)","ror":"https://ror.org/0072d4h61","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210089756"]},{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Wu","raw_affiliation_strings":["Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","institution_ids":["https://openalex.org/I149240348"]},{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348","https://openalex.org/I4210089756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100702026","display_name":"Yaoyao Li","orcid":"https://orcid.org/0000-0002-8762-9615"},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaoyao Li","raw_affiliation_strings":["Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","institution_ids":["https://openalex.org/I149240348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045689983","display_name":"Jing Zhao","orcid":"https://orcid.org/0000-0002-8029-3514"},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]},{"id":"https://openalex.org/I4210089756","display_name":"Bioscience (China)","ror":"https://ror.org/0072d4h61","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210089756"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Zhao","raw_affiliation_strings":["Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","institution_ids":["https://openalex.org/I149240348"]},{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348","https://openalex.org/I4210089756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049058376","display_name":"Fengping Du","orcid":null},"institutions":[{"id":"https://openalex.org/I4210089756","display_name":"Bioscience (China)","ror":"https://ror.org/0072d4h61","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210089756"]},{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fengping Du","raw_affiliation_strings":["Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","institution_ids":["https://openalex.org/I149240348"]},{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348","https://openalex.org/I4210089756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101844778","display_name":"Mingxia Song","orcid":"https://orcid.org/0000-0002-7558-8334"},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]},{"id":"https://openalex.org/I4210089756","display_name":"Bioscience (China)","ror":"https://ror.org/0072d4h61","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210089756"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingxia Song","raw_affiliation_strings":["Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China","institution_ids":["https://openalex.org/I149240348"]},{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348","https://openalex.org/I4210089756"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5115695391","display_name":"Renjun Wang","orcid":"https://orcid.org/0000-0003-0058-6219"},"institutions":[{"id":"https://openalex.org/I149240348","display_name":"Jilin Normal University","ror":"https://ror.org/00xtsag93","country_code":"CN","type":"education","lineage":["https://openalex.org/I149240348"]},{"id":"https://openalex.org/I4210089756","display_name":"Bioscience (China)","ror":"https://ror.org/0072d4h61","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210089756"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Renjun Wang","raw_affiliation_strings":["Department of Biotechnology, School of Life Science, Jilin Normal University, Siping, China","Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, School of Life Science, Jilin Normal University, Siping, China","institution_ids":["https://openalex.org/I149240348"]},{"raw_affiliation_string":"Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China,","institution_ids":["https://openalex.org/I149240348","https://openalex.org/I4210089756"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101398997"],"corresponding_institution_ids":["https://openalex.org/I149240348","https://openalex.org/I4210089756"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":2.392,"has_fulltext":false,"cited_by_count":65,"citation_normalized_percentile":{"value":0.89147139,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"2016","issue":null,"first_page":"baw159","last_page":"baw159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigenetics","display_name":"Epigenetics","score":0.8733340501785278},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.5634743571281433},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5420237183570862},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.5413243174552917},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.48108789324760437},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.4245552718639374},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.29058849811553955},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2870088219642639},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2614660859107971},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.14400747418403625},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.08810946345329285}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.8733340501785278},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.5634743571281433},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5420237183570862},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.5413243174552917},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.48108789324760437},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4245552718639374},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29058849811553955},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2870088219642639},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2614660859107971},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14400747418403625},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.08810946345329285}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/database/baw159","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baw159","pdf_url":null,"source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:28025347","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28025347","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:open-archive.highwire.org:databa:2016/0/baw159","is_oa":false,"landing_page_url":"http://database.oxfordjournals.org/cgi/content/short/2016/0/baw159","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:pubmedcentral.nih.gov:5199199","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5199199","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Database (Oxford)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/database/baw159","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baw159","pdf_url":null,"source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3245613155","display_name":null,"funder_award_id":"31301043","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4990293795","display_name":null,"funder_award_id":"31540035","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5317641822","display_name":null,"funder_award_id":"81202527","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1964970753","https://openalex.org/W1969654508","https://openalex.org/W1975705914","https://openalex.org/W1975875968","https://openalex.org/W1990636453","https://openalex.org/W1998931089","https://openalex.org/W2004380688","https://openalex.org/W2005829971","https://openalex.org/W2014364284","https://openalex.org/W2027482274","https://openalex.org/W2033078160","https://openalex.org/W2041535798","https://openalex.org/W2043253380","https://openalex.org/W2047149866","https://openalex.org/W2048389974","https://openalex.org/W2053213384","https://openalex.org/W2064046837","https://openalex.org/W2076227442","https://openalex.org/W2078079917","https://openalex.org/W2080608726","https://openalex.org/W2094362542","https://openalex.org/W2098903417","https://openalex.org/W2109010689","https://openalex.org/W2116021928","https://openalex.org/W2116068882","https://openalex.org/W2118258530","https://openalex.org/W2128980492","https://openalex.org/W2130479394","https://openalex.org/W2133117955","https://openalex.org/W2134009718","https://openalex.org/W2152182332","https://openalex.org/W2162151166","https://openalex.org/W2164975333","https://openalex.org/W2168859815","https://openalex.org/W2170146596","https://openalex.org/W2177317049","https://openalex.org/W2201238125","https://openalex.org/W2204695023","https://openalex.org/W2274523015","https://openalex.org/W2290460030","https://openalex.org/W2320983896","https://openalex.org/W2331629354","https://openalex.org/W2343743605","https://openalex.org/W2410743230"],"related_works":["https://openalex.org/W4366603091","https://openalex.org/W2485141070","https://openalex.org/W2411374999","https://openalex.org/W2083798468","https://openalex.org/W4380318195","https://openalex.org/W2013003323","https://openalex.org/W1981076832","https://openalex.org/W2024773645","https://openalex.org/W2001717001","https://openalex.org/W2043147644"],"abstract_inverted_index":{"Epigenetic":[0,26],"drugs":[1],"are":[2,98],"chemical":[3],"compounds":[4],"that":[5],"target":[6],"disordered":[7],"post-translational":[8],"modification":[9],"of":[10,20,58,61,87,147,162,167,202],"histone":[11],"proteins":[12],"and":[13,17,44,56,69,73,104,121,145,155,177,208],"DNA":[14],"through":[15],"enzymes,":[16],"the":[18,143],"recognition":[19],"these":[21,102],"changes":[22],"by":[23,35,41,48,101],"adaptor":[24],"proteins.":[25],"drug-related":[27,113],"experimental":[28,114],"data":[29,62,80,92,184],"such":[30,94],"as":[31,95],"gene":[32],"expression":[33],"probed":[34,40,47],"high-throughput":[36,96,176],"sequencing,":[37],"co-crystal":[38],"structure":[39],"X-RAY":[42],"diffraction":[43],"binding":[45],"constants":[46],"bio-assay":[49],"have":[50],"become":[51],"widely":[52],"available.":[53],"The":[54,135,159],"mining":[55],"integration":[57,146],"multiple":[59],"kinds":[60,166,201],"can":[63,83],"be":[64],"beneficial":[65],"to":[66,119,182],"drug":[67,70,138,149,205],"discovery":[68],"repurposing.":[71],"HEMD":[72,120],"other":[74,122],"epigenetic":[75,79,88,112,123,133,137,148],"databases":[76,103],"store":[77],"comprehensively":[78],"where":[81],"users":[82],"acquire":[84],"segmental":[85],"information":[86],"drugs.":[89,134],"However,":[90],"some":[91],"types":[93],"datasets":[97,150,203],"not":[99,107],"provide":[100],"they":[105],"do":[106],"support":[108],"flexible":[109,186],"queries":[110],"for":[111,131,199],"data.":[115],"Therefore,":[116],"in":[117,191],"reference":[118],"databases,":[124],"we":[125],"developed":[126],"a":[127],"relatively":[128],"comprehensive":[129],"database":[130,139],"human":[132,136],"(HEDD)":[140],"focuses":[141],"on":[142],"storage":[144],"obtained":[151],"from":[152],"laboratory":[153],"experiments":[154],"manually":[156],"curated":[157],"information.":[158],"latest":[160],"release":[161],"HEDD":[163],"incorporates":[164],"five":[165],"datasets:":[168],"(i)":[169],"drug,":[170],"(ii)":[171],"target,":[172],"(iii)":[173],"disease,":[174],"(vi)":[175],"(v)":[178],"complex.":[179],"In":[180],"order":[181],"facilitate":[183],"extraction,":[185],"search":[187],"options":[188],"were":[189],"built":[190],"HEDD,":[192],"which":[193],"allowed":[194],"an":[195],"unlimited":[196],"condition":[197],"query":[198],"specific":[200],"using":[204],"names,":[206],"diseases":[207],"experiment":[209],"types.Database":[210],"URL:":[211],"http://hedds.org/.":[212]},"counts_by_year":[{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}