{"id":"https://openalex.org/W2285488284","doi":"https://doi.org/10.1093/database/bav125","title":"Regulators of Androgen Action Resource: a one-stop shop for the comprehensive study of androgen receptor action","display_name":"Regulators of Androgen Action Resource: a one-stop shop for the comprehensive study of androgen receptor action","publication_year":2016,"publication_date":"2016-02-14","ids":{"openalex":"https://openalex.org/W2285488284","doi":"https://doi.org/10.1093/database/bav125","mag":"2285488284","pmid":"https://pubmed.ncbi.nlm.nih.gov/26876983"},"language":"en","primary_location":{"id":"doi:10.1093/database/bav125","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/bav125","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/bav125/8222552/bav125.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/bav125/8222552/bav125.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084405217","display_name":"Adam DePriest","orcid":"https://orcid.org/0009-0007-8368-926X"},"institutions":[{"id":"https://openalex.org/I4210145812","display_name":"Cancer Genetics (United States)","ror":"https://ror.org/05feyya22","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam D. DePriest","raw_affiliation_strings":["Department of Cancer Genetics heemerh@ccf.org"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Genetics heemerh@ccf.org","institution_ids":["https://openalex.org/I4210145812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041748326","display_name":"Michael V. Fiandalo","orcid":"https://orcid.org/0000-0002-3558-2712"},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael V. Fiandalo","raw_affiliation_strings":["Department of Urology, Roswell Park Cancer Institute, Buffalo, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Roswell Park Cancer Institute, Buffalo, NY, USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018902240","display_name":"Simon Schlanger","orcid":null},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simon Schlanger","raw_affiliation_strings":["Department of Cancer Biology, Cleveland Clinic, Cleveland, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology, Cleveland Clinic, Cleveland, OH, USA","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005338184","display_name":"Frederike Heemers","orcid":null},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederike Heemers","raw_affiliation_strings":["Department of Cancer Biology, Cleveland Clinic, Cleveland, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology, Cleveland Clinic, Cleveland, OH, USA","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074919849","display_name":"James L. Mohler","orcid":"https://orcid.org/0000-0002-7726-3795"},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James L. Mohler","raw_affiliation_strings":["Department of Urology, Roswell Park Cancer Institute, Buffalo, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Roswell Park Cancer Institute, Buffalo, NY, USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100339600","display_name":"Song Liu","orcid":"https://orcid.org/0000-0002-8719-0833"},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Song Liu","raw_affiliation_strings":["Department of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, NY, USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026531632","display_name":"Hannelore V. Heemers","orcid":"https://orcid.org/0000-0001-9137-5083"},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hannelore V. Heemers","raw_affiliation_strings":["Department of Cancer Biology, Cleveland Clinic, Cleveland, OH, USA Department of Urology Department of Hematology/Medical Oncology, Cleveland Clinic, Cleveland, OH, USA heemerh@ccf.org"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology, Cleveland Clinic, Cleveland, OH, USA Department of Urology Department of Hematology/Medical Oncology, Cleveland Clinic, Cleveland, OH, USA heemerh@ccf.org","institution_ids":["https://openalex.org/I1316902750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5026531632"],"corresponding_institution_ids":["https://openalex.org/I1316902750"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":2.5391,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.89273058,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"2016","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9922999739646912,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/androgen-receptor","display_name":"Androgen receptor","score":0.8300414681434631},{"id":"https://openalex.org/keywords/intracrine","display_name":"Intracrine","score":0.7000285387039185},{"id":"https://openalex.org/keywords/androgen","display_name":"Androgen","score":0.5846526622772217},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"Prostate cancer","score":0.4966292977333069},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4633185863494873},{"id":"https://openalex.org/keywords/nuclear-receptor","display_name":"Nuclear receptor","score":0.42792823910713196},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.4106120467185974},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4098021686077118},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.3979146480560303},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3035019636154175},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.2692180871963501},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2637028992176056},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.20206448435783386},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.17743250727653503},{"id":"https://openalex.org/keywords/hormone","display_name":"Hormone","score":0.1459331214427948},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1440347135066986},{"id":"https://openalex.org/keywords/paracrine-signalling","display_name":"Paracrine signalling","score":0.07576495409011841}],"concepts":[{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.8300414681434631},{"id":"https://openalex.org/C63263939","wikidata":"https://www.wikidata.org/wiki/Q3153691","display_name":"Intracrine","level":4,"score":0.7000285387039185},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.5846526622772217},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.4966292977333069},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4633185863494873},{"id":"https://openalex.org/C63932345","wikidata":"https://www.wikidata.org/wiki/Q422500","display_name":"Nuclear receptor","level":4,"score":0.42792823910713196},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4106120467185974},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4098021686077118},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.3979146480560303},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3035019636154175},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2692180871963501},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2637028992176056},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.20206448435783386},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.17743250727653503},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.1459331214427948},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1440347135066986},{"id":"https://openalex.org/C7876069","wikidata":"https://www.wikidata.org/wiki/Q14873666","display_name":"Paracrine signalling","level":3,"score":0.07576495409011841}],"mesh":[{"descriptor_ui":"D000728","descriptor_name":"Androgens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000728","descriptor_name":"Androgens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000728","descriptor_name":"Androgens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011944","descriptor_name":"Receptors, Androgen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011944","descriptor_name":"Receptors, Androgen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011944","descriptor_name":"Receptors, Androgen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/database/bav125","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/bav125","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/bav125/8222552/bav125.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:26876983","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26876983","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:open-archive.highwire.org:databa:2016/0/bav125","is_oa":false,"landing_page_url":"http://database.oxfordjournals.org/cgi/content/short/2016/0/bav125","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:pubmedcentral.nih.gov:4752970","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4752970","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Database (Oxford)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/database/bav125","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/bav125","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/bav125/8222552/bav125.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G6369261575","display_name":null,"funder_award_id":"CA166440","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7898069094","display_name":null,"funder_award_id":"R01 CA166440","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8294399631","display_name":null,"funder_award_id":"CA166440","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8529445282","display_name":null,"funder_award_id":"P30 CA016056","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306163","display_name":"Prostate Cancer Foundation","ror":"https://ror.org/01npwtv09"},{"id":"https://openalex.org/F4320309680","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2285488284.pdf","grobid_xml":"https://content.openalex.org/works/W2285488284.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W21117391","https://openalex.org/W1740737174","https://openalex.org/W1965455518","https://openalex.org/W1972459670","https://openalex.org/W1988708470","https://openalex.org/W1989689178","https://openalex.org/W1989778011","https://openalex.org/W1998691242","https://openalex.org/W2001888139","https://openalex.org/W2010054556","https://openalex.org/W2010246016","https://openalex.org/W2010349354","https://openalex.org/W2017896209","https://openalex.org/W2024952193","https://openalex.org/W2025838418","https://openalex.org/W2026496126","https://openalex.org/W2046885420","https://openalex.org/W2049361027","https://openalex.org/W2049476249","https://openalex.org/W2051025382","https://openalex.org/W2053116646","https://openalex.org/W2055655957","https://openalex.org/W2063908773","https://openalex.org/W2064293531","https://openalex.org/W2068037114","https://openalex.org/W2071802200","https://openalex.org/W2077301757","https://openalex.org/W2077907808","https://openalex.org/W2080134152","https://openalex.org/W2080156485","https://openalex.org/W2080748037","https://openalex.org/W2083806052","https://openalex.org/W2088516053","https://openalex.org/W2089518544","https://openalex.org/W2098193929","https://openalex.org/W2112568160","https://openalex.org/W2114913629","https://openalex.org/W2120097451","https://openalex.org/W2121406897","https://openalex.org/W2129824829","https://openalex.org/W2129833757","https://openalex.org/W2138504446","https://openalex.org/W2144492823","https://openalex.org/W2150039609","https://openalex.org/W2150919715","https://openalex.org/W2151317340","https://openalex.org/W2152689753","https://openalex.org/W2157980218","https://openalex.org/W2157985656","https://openalex.org/W2158274171","https://openalex.org/W2158465395","https://openalex.org/W2160975559","https://openalex.org/W2162605481","https://openalex.org/W2164092182","https://openalex.org/W2165177861","https://openalex.org/W2167749314","https://openalex.org/W2169961966","https://openalex.org/W2219978888","https://openalex.org/W2316591685","https://openalex.org/W2321220648","https://openalex.org/W2322485784","https://openalex.org/W2489506968","https://openalex.org/W2768197275","https://openalex.org/W4231779489","https://openalex.org/W4241502657"],"related_works":["https://openalex.org/W2752706152","https://openalex.org/W2169608764","https://openalex.org/W2418728032","https://openalex.org/W2144492823","https://openalex.org/W2203960497","https://openalex.org/W2033566079","https://openalex.org/W2327862400","https://openalex.org/W3009569511","https://openalex.org/W2037219617","https://openalex.org/W2365928272"],"abstract_inverted_index":{"Androgen":[0,46,137],"receptor":[1],"(AR)":[2],"is":[3,9,27,194,205,274,291],"a":[4,141,197,208,275],"ligand-activated":[5],"transcription":[6],"factor":[7],"that":[8,34,92,162,223,280,290],"the":[10,42,134,232,270],"main":[11],"target":[12],"for":[13,159,174],"treatment":[14,58],"of":[15,21,88,115,126,136,171,192,239,259],"non-organ-confined":[16],"prostate":[17],"cancer":[18],"(CaP).":[19],"Failure":[20],"life-prolonging":[22],"AR-targeting":[23],"androgen":[24,37,49],"deprivation":[25],"therapy":[26],"due":[28],"to":[29,73,122,190,220,226,229,246,257,266,287,293],"flexibility":[30],"in":[31,41,166,180,184,196,207,235,269],"steroidogenic":[32],"pathways":[33],"control":[35],"intracrine":[36],"levels":[38],"and":[39,51,69,76,99,103,111,128,144,157,169,173,201,212,227,254,284],"variability":[40],"AR":[43,127],"transcriptional":[44],"output.":[45],"biosynthesis":[47],"enzymes,":[48],"transporters":[50],"AR-associated":[52,176],"coregulators":[53],"are":[54,63,71,77,93,107,182,224],"attractive":[55],"novel":[56],"CaP":[57,296],"targets.":[59],"These":[60],"proteins,":[61],"however,":[62],"characterized":[64],"by":[65],"multiple":[66,96],"transcript":[67],"variants":[68],"isoforms,":[70],"subject":[72],"genomic":[74],"alterations,":[75],"differentially":[78],"expressed":[79],"among":[80],"CaPs.":[81],"Determining":[82],"their":[83],"therapeutic":[84],"potential":[85,129],"requires":[86],"evaluation":[87],"extensive,":[89],"diverse":[90],"datasets":[91,106],"dispersed":[94],"over":[95],"databases,":[97,253],"websites":[98],"literature":[100],"reports.":[101],"Mining":[102],"integrating":[104],"these":[105],"cumbersome,":[108],"time-consuming":[109],"tasks":[110],"provide":[112,263],"only":[113],"snapshots":[114],"relevant":[116],"information.":[117],"To":[118],"overcome":[119],"this":[120],"impediment":[121],"effective,":[123],"efficient":[124],"study":[125],"drug":[130],"targets,":[131],"we":[132],"developed":[133],"Regulators":[135],"Action":[138],"Resource":[139],"(RAAR),":[140],"non-redundant,":[142],"curated":[143],"user-friendly":[145],"searchable":[146],"web":[147],"interface.":[148],"RAAR":[149,181,243,273],"centralizes":[150],"information":[151,204,233,289],"on":[152],"gene":[153,203],"function,":[154],"clinical":[155],"relevance,":[156],"resources":[158],"55":[160],"genes":[161],"encode":[163],"proteins":[164],"involved":[165],"biosynthesis,":[167],"metabolism":[168],"transport":[170],"androgens":[172,193],"274":[175],"coregulator":[177,202],"genes.":[178],"Data":[179],"organized":[183],"two":[185],"levels:":[186],"(i)":[187],"Information":[188],"pertaining":[189],"production":[191],"contained":[195],"'pre-receptor":[198],"level'":[199,210],"database,":[200,211],"provided":[206,234],"'post-receptor":[209],"(ii)":[213],"an":[214],"'other":[215],"resources'":[216],"database":[217],"contains":[218],"links":[219],"additional":[221],"databases":[222],"complementary":[225],"useful":[228],"pursue":[230],"further":[231],"RAAR.":[236],"For":[237],"each":[238],"its":[240],"329":[241],"entries,":[242],"provides":[244,281],"access":[245,256,265,286],"more":[247],"than":[248],"20":[249],"well-curated":[250],"publicly":[251],"available":[252,278],"thus,":[255],"thousands":[258],"data":[260],"points.":[261],"Hyperlinks":[262],"direct":[264],"gene-specific":[267],"entries":[268],"respective":[271],"database(s).":[272],"novel,":[276],"freely":[277],"resource":[279],"fast,":[282],"reliable":[283],"easy":[285],"integrated":[288],"needed":[292],"develop":[294],"alternative":[295],"therapies.":[297],"Database":[298],"URL:":[299],"http://www.lerner.ccf.org/cancerbio/heemers/RAAR/search/.":[300]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":5}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}