{"id":"https://openalex.org/W4410019894","doi":"https://doi.org/10.1093/database/baaf032","title":"STCDB4ND: a signal transduction classification database for neurological diseases","display_name":"STCDB4ND: a signal transduction classification database for neurological diseases","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4410019894","doi":"https://doi.org/10.1093/database/baaf032","pmid":"https://pubmed.ncbi.nlm.nih.gov/40315246"},"language":"en","primary_location":{"id":"doi:10.1093/database/baaf032","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baaf032","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baaf032/63045365/baaf032.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baaf032/63045365/baaf032.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101888617","display_name":"Bo Gong","orcid":"https://orcid.org/0000-0003-0400-7069"},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Boyan Gong","raw_affiliation_strings":["Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,","institution_ids":["https://openalex.org/I76130692","https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103241189","display_name":"Sida Li","orcid":"https://orcid.org/0000-0003-3893-8945"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]},{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sida Li","raw_affiliation_strings":["Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,","institution_ids":["https://openalex.org/I76130692","https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074324726","display_name":"Yifan Chen","orcid":"https://orcid.org/0000-0003-2628-5764"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]},{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yifan Chen","raw_affiliation_strings":["Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,","institution_ids":["https://openalex.org/I76130692","https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100697075","display_name":"Liya Liu","orcid":"https://orcid.org/0000-0003-0405-6637"},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liya Liu","raw_affiliation_strings":["Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,","institution_ids":["https://openalex.org/I76130692","https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001882549","display_name":"Ralf Hofest\u00e4dt","orcid":null},"institutions":[{"id":"https://openalex.org/I20121455","display_name":"Bielefeld University","ror":"https://ror.org/02hpadn98","country_code":"DE","type":"education","lineage":["https://openalex.org/I20121455"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ralf Hofest\u00e4dt","raw_affiliation_strings":["Department of Bioinformatics/Medical Informatics, Faculty of Technology, Bielefeld University , Bielefeld 33501,"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics/Medical Informatics, Faculty of Technology, Bielefeld University , Bielefeld 33501,","institution_ids":["https://openalex.org/I20121455"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100423292","display_name":"Ming Chen","orcid":"https://orcid.org/0000-0002-9677-1699"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]},{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming Chen","raw_affiliation_strings":["Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,","Zhejiang Key Laboratory of Multi-omics Precision Diagnosis and Treatment of Liver Diseases, Zhejiang University , Hangzhou 310058,"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Institute of Biophysics, College of Life Sciences; Institute of Hematology, Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang University , Hangzhou 310058,","institution_ids":["https://openalex.org/I76130692","https://openalex.org/I4210166576"]},{"raw_affiliation_string":"Zhejiang Key Laboratory of Multi-omics Precision Diagnosis and Treatment of Liver Diseases, Zhejiang University , Hangzhou 310058,","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5101888617"],"corresponding_institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08528476,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2025","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9835000038146973,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5237850546836853},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"Signal transduction","score":0.4773968756198883},{"id":"https://openalex.org/keywords/transduction","display_name":"Transduction (biophysics)","score":0.429864764213562},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.42671045660972595},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3265356421470642},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.32336029410362244},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.16825109720230103},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.0866696834564209}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5237850546836853},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4773968756198883},{"id":"https://openalex.org/C15152581","wikidata":"https://www.wikidata.org/wiki/Q7833966","display_name":"Transduction (biophysics)","level":2,"score":0.429864764213562},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.42671045660972595},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3265356421470642},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.32336029410362244},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16825109720230103},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0866696834564209},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/database/baaf032","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baaf032","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baaf032/63045365/baaf032.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:40315246","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40315246","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmid:40402766","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40402766","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12047452","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12047452","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Database (Oxford)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/database/baaf032","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baaf032","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baaf032/63045365/baaf032.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322927","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410019894.pdf"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W2002081498","https://openalex.org/W2031218556","https://openalex.org/W2066636486","https://openalex.org/W2087064593","https://openalex.org/W2126676741","https://openalex.org/W2900090807","https://openalex.org/W2912105929","https://openalex.org/W3096828292","https://openalex.org/W3102147110","https://openalex.org/W3211402536","https://openalex.org/W3212063608","https://openalex.org/W4308834893","https://openalex.org/W4309506674","https://openalex.org/W4312057643","https://openalex.org/W4381715389","https://openalex.org/W4386699327","https://openalex.org/W4388425030","https://openalex.org/W4391322948"],"related_works":["https://openalex.org/W2890433954","https://openalex.org/W2053366384","https://openalex.org/W2369434682","https://openalex.org/W4246428841","https://openalex.org/W1981686597","https://openalex.org/W2966233672","https://openalex.org/W2030055732","https://openalex.org/W2538234910","https://openalex.org/W4210978881","https://openalex.org/W2562955175"],"abstract_inverted_index":{"Neurological":[0],"disorders":[1],"pose":[2],"significant":[3],"global":[4],"health":[5],"challenges":[6],"due":[7],"to":[8,34,117],"their":[9],"complex":[10,121],"etiology":[11],"and":[12,29,55,97,109,135,156],"insufficient":[13],"understanding":[14,151],"of":[15,26,59,125,152],"underlying":[16],"mechanisms.":[17],"Signal":[18],"transduction":[19,76],"pathways":[20,44,54,77,128,155],"are":[21],"critical":[22],"in":[23,172,182],"the":[24,47,60,83,150,178,183],"pathophysiology":[25],"these":[27,53,65,120],"diseases":[28],"have":[30],"been":[31],"extensively":[32],"studied":[33],"develop":[35],"therapeutic":[36,159],"interventions.":[37],"However,":[38],"existing":[39,137],"databases":[40],"for":[41,92,148,170],"biological":[42],"signal":[43,75],"often":[45],"overlook":[46],"dynamic":[48],"interactions":[49,96],"between":[50],"entities":[51],"within":[52],"lack":[56],"standardized":[57],"representations":[58],"signaling":[61,133],"processes.":[62],"To":[63],"address":[64],"limitations,":[66],"we":[67,162,176],"present":[68],"STCDB4ND,":[69],"a":[70,89,110,145],"specialized":[71],"database":[72,101,181],"focused":[73],"on":[74,139],"associated":[78],"with":[79],"neurological":[80,126,153],"diseases.":[81],"Utilizing":[82],"ST":[84],"classification":[85],"system,":[86],"STCDB4ND":[87,130,142],"provides":[88],"unified":[90],"framework":[91],"pathway":[93,98],"representation,":[94],"emphasizing":[95],"characteristics.":[99],"The":[100],"features":[102],"advanced":[103],"visualization":[104],"tools,":[105],"network":[106],"analysis":[107,124],"capabilities,":[108],"key":[111,132],"factor":[112],"identification":[113],"module,":[114],"enabling":[115],"researchers":[116,171],"comprehensively":[118],"study":[119],"networks.":[122],"Our":[123],"disease-related":[127],"using":[129],"revealed":[131],"factors":[134],"supported":[136],"findings":[138],"pathogenic":[140],"mechanisms":[141],"serves":[143],"as":[144,175],"valuable":[146],"resource":[147],"advancing":[149],"disease":[154],"promoting":[157],"novel":[158],"approaches.":[160],"And":[161],"believe":[163],"that":[164],"STCDB":[165,179],"will":[166],"provide":[167],"greater":[168],"convenience":[169],"various":[173],"fields":[174],"expand":[177],"system's":[180],"future.":[184],"Database":[185],"URL:":[186],"https://bis.zju.edu.cn/STCDB.":[187]},"counts_by_year":[],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-05-02T00:00:00"}