{"id":"https://openalex.org/W4389262295","doi":"https://doi.org/10.1093/database/baad085","title":"Design of\u00a0the formalized and\u00a0integrated Alzheimer\u2019s Disease Ontology and\u00a0its application in\u00a0retrieving textual data via text mining","display_name":"Design of\u00a0the formalized and\u00a0integrated Alzheimer\u2019s Disease Ontology and\u00a0its application in\u00a0retrieving textual data via text mining","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4389262295","doi":"https://doi.org/10.1093/database/baad085","pmid":"https://pubmed.ncbi.nlm.nih.gov/38041858"},"language":"en","primary_location":{"id":"doi:10.1093/database/baad085","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1093/database/baad085","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baad085/53975962/baad085.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baad085/53975962/baad085.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008851175","display_name":"Bide Zhang","orcid":"https://orcid.org/0000-0002-6571-0033"},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bide Zhang","raw_affiliation_strings":["Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":"https://orcid.org/0000-0002-6571-0033","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078369553","display_name":"Vanessa Lage\u2010Rupprecht","orcid":"https://orcid.org/0000-0003-1374-8184"},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Vanessa Lage-Rupprecht","raw_affiliation_strings":["Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":"https://orcid.org/0000-0003-1374-8184","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061101746","display_name":"Philipp Wegner","orcid":"https://orcid.org/0000-0003-1159-9269"},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Philipp Wegner","raw_affiliation_strings":["Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":"https://orcid.org/0000-0003-1159-9269","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010974805","display_name":"Astghik Sargsyan","orcid":"https://orcid.org/0000-0002-5860-6369"},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Astghik Sargsyan","raw_affiliation_strings":["Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":"https://orcid.org/0000-0002-5860-6369","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036639166","display_name":"Stephan Gebel","orcid":"https://orcid.org/0000-0001-5086-8324"},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stephan Gebel","raw_affiliation_strings":["Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016675379","display_name":"Marc Jacobs","orcid":"https://orcid.org/0000-0003-4153-3930"},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marc Jacobs","raw_affiliation_strings":["Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":"https://orcid.org/0000-0003-4153-3930","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085915066","display_name":"J\u00fcrgen Klein","orcid":null},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00fcrgen Klein","raw_affiliation_strings":["Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003139478","display_name":"Martin Hofmann\u2010Apitius","orcid":"https://orcid.org/0000-0001-9012-6720"},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Hofmann-Apitius","raw_affiliation_strings":["Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":"https://orcid.org/0000-0001-9012-6720","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000031695","display_name":"Alpha Tom Kodamullil","orcid":"https://orcid.org/0000-0001-9896-3531"},"institutions":[{"id":"https://openalex.org/I4210098248","display_name":"Fraunhofer Institute for Algorithms and Scientific Computing","ror":"https://ror.org/00trw9c49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210098248","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alpha Tom Kodamullil","raw_affiliation_strings":["Causality Biomodels, Kinfra Hi-Tech Park , Kalamassery, Cochin, Kerala 683503, India","Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany"],"raw_orcid":"https://orcid.org/0000-0001-9896-3531","affiliations":[{"raw_affiliation_string":"Causality Biomodels, Kinfra Hi-Tech Park , Kalamassery, Cochin, Kerala 683503, India","institution_ids":[]},{"raw_affiliation_string":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) , Schloss Birlinghoven, Sankt Augustin 53754, Germany","institution_ids":["https://openalex.org/I4210098248"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210098248"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.31804657,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2023","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10215","display_name":"Semantic Web and Ontologies","score":0.9793000221252441,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9718000292778015,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.8209362030029297},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6812966465950012},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.5270317196846008},{"id":"https://openalex.org/keywords/open-biomedical-ontologies","display_name":"Open Biomedical Ontologies","score":0.5123432874679565},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.43408501148223877},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.4027208089828491},{"id":"https://openalex.org/keywords/upper-ontology","display_name":"Upper ontology","score":0.39528417587280273},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3693268597126007},{"id":"https://openalex.org/keywords/semantic-web","display_name":"Semantic Web","score":0.2698379158973694},{"id":"https://openalex.org/keywords/suggested-upper-merged-ontology","display_name":"Suggested Upper Merged Ontology","score":0.26210373640060425},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.16006579995155334},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.08440521359443665}],"concepts":[{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.8209362030029297},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6812966465950012},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.5270317196846008},{"id":"https://openalex.org/C137982476","wikidata":"https://www.wikidata.org/wiki/Q7072326","display_name":"Open Biomedical Ontologies","level":5,"score":0.5123432874679565},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43408501148223877},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.4027208089828491},{"id":"https://openalex.org/C78726541","wikidata":"https://www.wikidata.org/wiki/Q3882785","display_name":"Upper ontology","level":3,"score":0.39528417587280273},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3693268597126007},{"id":"https://openalex.org/C2129575","wikidata":"https://www.wikidata.org/wiki/Q54837","display_name":"Semantic Web","level":2,"score":0.2698379158973694},{"id":"https://openalex.org/C50971890","wikidata":"https://www.wikidata.org/wiki/Q7635093","display_name":"Suggested Upper Merged Ontology","level":4,"score":0.26210373640060425},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16006579995155334},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08440521359443665},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/database/baad085","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1093/database/baad085","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baad085/53975962/baad085.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:38041858","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38041858","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10693436","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10693436","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10693436/pdf/baad085.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Database (Oxford)","raw_type":"Text"},{"id":"pmh:oai:publica.fraunhofer.de:publica/480982","is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/480982","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1093/database/baad085","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1093/database/baad085","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baad085/53975962/baad085.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5894663607","display_name":null,"funder_award_id":"#18006CB","funder_id":"https://openalex.org/F4320311828","funder_display_name":"Alzheimer Forschung Initiative"}],"funders":[{"id":"https://openalex.org/F4320311828","display_name":"Alzheimer Forschung Initiative","ror":"https://ror.org/01arayx28"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4389262295.pdf"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W184303886","https://openalex.org/W1483118642","https://openalex.org/W1523814549","https://openalex.org/W1534628288","https://openalex.org/W1802346448","https://openalex.org/W1976357608","https://openalex.org/W1984761526","https://openalex.org/W2022313041","https://openalex.org/W2030197114","https://openalex.org/W2050097598","https://openalex.org/W2104542816","https://openalex.org/W2113142309","https://openalex.org/W2115017507","https://openalex.org/W2129082847","https://openalex.org/W2129497119","https://openalex.org/W2141869602","https://openalex.org/W2261812172","https://openalex.org/W2399303024","https://openalex.org/W2404810405","https://openalex.org/W2582524520","https://openalex.org/W2750956523","https://openalex.org/W2761387204","https://openalex.org/W2798054687","https://openalex.org/W2884056365","https://openalex.org/W2893696970","https://openalex.org/W2919458375","https://openalex.org/W3112948680","https://openalex.org/W3128111279","https://openalex.org/W3136609014","https://openalex.org/W3210487037","https://openalex.org/W4205605356","https://openalex.org/W4250519177","https://openalex.org/W4301261115","https://openalex.org/W4317542724","https://openalex.org/W4353112603","https://openalex.org/W4385255906","https://openalex.org/W4385660176","https://openalex.org/W6607485555","https://openalex.org/W6713748237","https://openalex.org/W6760428427","https://openalex.org/W6803613226","https://openalex.org/W6845914902"],"related_works":["https://openalex.org/W1506177826","https://openalex.org/W2726617685","https://openalex.org/W2127299687","https://openalex.org/W2111194626","https://openalex.org/W1562796463","https://openalex.org/W2074013882","https://openalex.org/W2399880385","https://openalex.org/W2397553363","https://openalex.org/W1794266373","https://openalex.org/W4206428734"],"abstract_inverted_index":{"As":[0],"one":[1],"of":[2,39,89,103,172,182,220],"the":[3,9,51,56,85,90,100,104,107,116,183,200,211,218,221,229],"leading":[4],"causes":[5],"for":[6],"dementia":[7],"in":[8,150,224,235],"population,":[10],"it":[11,156],"is":[12,157],"imperative":[13],"that":[14,155],"we":[15,216],"discern":[16],"exactly":[17],"why":[18],"Alzheimer's":[19,92,108],"disease":[20,80],"(AD)":[21],"has":[22],"a":[23,32],"strong":[24],"molecular":[25,52],"association":[26],"with":[27,160,199],"beta-amyloid":[28],"and":[29,37,59,77,87,106,138,193,203,207,232],"tau.":[30],"Although":[31],"clear":[33],"understanding":[34,71],"about":[35,72,126],"etiology":[36],"pathogenesis":[38],"AD":[40,127,184],"remains":[41],"unsolved,":[42],"scientists":[43],"worldwide":[44],"have":[45],"dedicated":[46],"significant":[47],"efforts":[48],"to":[49,55,79,115],"discovering":[50],"interactions":[53],"linked":[54],"pathological":[57],"characteristics":[58],"potential":[60],"treatments.":[61],"Knowledge":[62],"representations,":[63],"such":[64,131],"as":[65,132,163,165],"domain":[66],"ontologies":[67],"encompassing":[68],"our":[69],"current":[70],"AD,":[73],"could":[74],"greatly":[75],"assist":[76],"contribute":[78],"research.":[81],"This":[82],"paper":[83],"describes":[84],"construction":[86],"application":[88],"integrated":[91,169],"Disease":[93,109],"Ontology":[94,111,205],"(ADO),":[95],"combining":[96],"selected":[97],"concepts":[98],"from":[99,120,128,228],"former":[101],"version":[102],"ADO":[105,145,170],"Mapping":[110],"(ADMO).":[112],"In":[113,213],"addition":[114],"existing":[117],"entities":[118],"available":[119],"these":[121],"knowledge":[122,125,162],"models,":[123],"essential":[124],"public":[129],"sources,":[130],"newly":[133],"discovered":[134],"risk":[135,187],"factor":[136,188],"genes":[137],"novel":[139],"treatments,":[140],"was":[141,208],"also":[142,147],"integrated.":[143],"The":[144,168,177,196],"can":[146],"be":[148],"leveraged":[149],"text":[151],"mining":[152],"scenarios":[153],"given":[154],"conceptually":[158],"enriched":[159],"domain-specific":[161],"well":[164],"their":[166],"relations.":[167],"consists":[171],"39":[173],"855":[174],"total":[175],"axioms.":[176],"ontology":[178,197,223],"covers":[179],"many":[180],"aspects":[181],"domain,":[185],"including":[186],"genes,":[189],"clinical":[190],"features,":[191],"treatments":[192],"experimental":[194],"models.":[195],"complies":[198],"Open":[201],"Biological":[202],"Biomedical":[204],"principles":[206],"accepted":[209],"by":[210],"foundry.":[212],"this":[214],"paper,":[215],"illustrate":[217],"role":[219],"presented":[222],"extracting":[225],"textual":[226],"information":[227],"SCAIView":[230],"database":[231],"key":[233],"measures":[234],"an":[236],"ADO-based":[237],"corpus.":[238],"Database":[239],"URL:":[240],"https://academic.oup.com/database.":[241]},"counts_by_year":[],"updated_date":"2026-06-26T08:34:08.712188","created_date":"2025-10-10T00:00:00"}