{"id":"https://openalex.org/W3080137602","doi":"https://doi.org/10.1093/database/baaa061","title":"LAMP2: a major update of the database linking antimicrobial peptides","display_name":"LAMP2: a major update of the database linking antimicrobial peptides","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3080137602","doi":"https://doi.org/10.1093/database/baaa061","mag":"3080137602","pmid":"https://pubmed.ncbi.nlm.nih.gov/32844169"},"language":"en","primary_location":{"id":"doi:10.1093/database/baaa061","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baaa061","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baaa061/33679481/baaa061.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baaa061/33679481/baaa061.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035058008","display_name":"Guizi Ye","orcid":"https://orcid.org/0000-0003-1576-0128"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guizi Ye","raw_affiliation_strings":["Kunshan Bio-Green Biotechnology Co., Ltd, Kunshan 215316, Jiangsu, China","State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kunshan Bio-Green Biotechnology Co., Ltd, Kunshan 215316, Jiangsu, China","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101470732","display_name":"Hongyu Wu","orcid":"https://orcid.org/0000-0002-8944-055X"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongyu Wu","raw_affiliation_strings":["Shanghai High-Tech United Bio-Technological R&D Co., Ltd, Shanghai 201206, China","State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai High-Tech United Bio-Technological R&D Co., Ltd, Shanghai 201206, China","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079518285","display_name":"Jinjiang Huang","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jinjiang Huang","raw_affiliation_strings":["Kunshan Bio-Green Biotechnology Co., Ltd, Kunshan 215316, Jiangsu, China","Shanghai High-Tech United Bio-Technological R&D Co., Ltd, Shanghai 201206, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kunshan Bio-Green Biotechnology Co., Ltd, Kunshan 215316, Jiangsu, China","institution_ids":[]},{"raw_affiliation_string":"Shanghai High-Tech United Bio-Technological R&D Co., Ltd, Shanghai 201206, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029264369","display_name":"Wei Wang","orcid":"https://orcid.org/0000-0002-3526-9160"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["Shanghai High-Tech United Bio-Technological R&D Co., Ltd, Shanghai 201206, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai High-Tech United Bio-Technological R&D Co., Ltd, Shanghai 201206, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077747028","display_name":"Kuikui Ge","orcid":null},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kuikui Ge","raw_affiliation_strings":["State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055581832","display_name":"Guodong Li","orcid":"https://orcid.org/0000-0002-4827-7493"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guodong Li","raw_affiliation_strings":["Shanghai High-Tech United Bio-Technological R&D Co., Ltd, Shanghai 201206, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai High-Tech United Bio-Technological R&D Co., Ltd, Shanghai 201206, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101962004","display_name":"Jiang F. Zhong","orcid":"https://orcid.org/0000-0003-0551-5161"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiang Zhong","raw_affiliation_strings":["State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102811391","display_name":"Qingshan Huang","orcid":"https://orcid.org/0000-0002-7558-3250"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qingshan Huang","raw_affiliation_strings":["State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China","institution_ids":["https://openalex.org/I24943067"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5102811391"],"corresponding_institution_ids":["https://openalex.org/I24943067"],"apc_list":{"value":1415,"currency":"GBP","value_usd":1735},"apc_paid":{"value":1415,"currency":"GBP","value_usd":1735},"fwci":6.655,"has_fulltext":true,"cited_by_count":130,"citation_normalized_percentile":{"value":0.97926653,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"2020","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.9891999959945679,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9728999733924866,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"Antimicrobial peptides","score":0.8059272766113281},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6062947511672974},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.5662408471107483},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.5644963979721069},{"id":"https://openalex.org/keywords/antimicrobial","display_name":"Antimicrobial","score":0.38126906752586365},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.15552622079849243},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.07632339000701904}],"concepts":[{"id":"https://openalex.org/C540938839","wikidata":"https://www.wikidata.org/wiki/Q1201508","display_name":"Antimicrobial peptides","level":3,"score":0.8059272766113281},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6062947511672974},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5662408471107483},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.5644963979721069},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.38126906752586365},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15552622079849243},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.07632339000701904},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D052899","descriptor_name":"Pore Forming Cytotoxic Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/database/baaa061","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baaa061","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baaa061/33679481/baaa061.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},{"id":"pmid:32844169","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32844169","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database : the journal of biological databases and curation","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7447557","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7447557","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database (Oxford)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/database/baaa061","is_oa":true,"landing_page_url":"https://doi.org/10.1093/database/baaa061","pdf_url":"https://academic.oup.com/database/article-pdf/doi/10.1093/database/baaa061/33679481/baaa061.pdf","source":{"id":"https://openalex.org/S4210201630","display_name":"Database","issn_l":"1758-0463","issn":["1758-0463"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311647","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/P4310311647"],"host_organization_lineage_names":["University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Database","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4699999988079071,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G5406876420","display_name":null,"funder_award_id":"2016YFD0501308","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321605","display_name":"Government of Jiangsu Province","ror":"https://ror.org/004svx814"},{"id":"https://openalex.org/F4320321851","display_name":"Fudan University","ror":"https://ror.org/013q1eq08"},{"id":"https://openalex.org/F4320326863","display_name":"State Key Laboratory of Genetic Engineering","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3080137602.pdf","grobid_xml":"https://content.openalex.org/works/W3080137602.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1931581539","https://openalex.org/W2014274241","https://openalex.org/W2015490529","https://openalex.org/W2035167810","https://openalex.org/W2035421428","https://openalex.org/W2035755292","https://openalex.org/W2056468827","https://openalex.org/W2072700935","https://openalex.org/W2080614447","https://openalex.org/W2095947376","https://openalex.org/W2099153308","https://openalex.org/W2121363497","https://openalex.org/W2129115651","https://openalex.org/W2129615006","https://openalex.org/W2131275757","https://openalex.org/W2163316049","https://openalex.org/W2175270296","https://openalex.org/W2222575139","https://openalex.org/W2553564063","https://openalex.org/W2588631349","https://openalex.org/W2739980134","https://openalex.org/W2795098196","https://openalex.org/W2899153547","https://openalex.org/W2965128681","https://openalex.org/W2976543668"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W1973192249","https://openalex.org/W2354039930","https://openalex.org/W2044458410","https://openalex.org/W4375855538","https://openalex.org/W2388831772","https://openalex.org/W3087020980","https://openalex.org/W2107525095","https://openalex.org/W4211241221"],"abstract_inverted_index":{"Antimicrobial":[0],"peptides":[1,70,178],"(AMPs)":[2],"have":[3,151,159],"been":[4,26,152,160],"regarded":[5,191],"as":[6,64,76,192],"a":[7,32,38,77,87,124],"potential":[8],"weapon":[9],"to":[10,34,42,80,104,207],"fight":[11],"against":[12],"drug-resistant":[13],"bacteria,":[14],"which":[15],"is":[16,31],"threating":[17],"the":[18,58,111,177,193,208],"globe.":[19],"Thus,":[20],"more":[21,23,116,128,136],"and":[22,45,60,102,127,149,167,190,199],"AMPs":[24,63,132],"had":[25],"designed":[27],"or":[28,135],"identified.":[29],"There":[30],"need":[33],"integrate":[35],"them":[36],"into":[37,154],"platform":[39],"for":[40,57,195],"researchers":[41],"facilitate":[43],"investigation":[44],"analyze":[46],"existing":[47],"AMPs.":[48],"The":[49,201],"AMP":[50,85,100,108,197],"database":[51,67,126,137],"has":[52],"become":[53],"an":[54,91],"important":[55],"tool":[56,79],"discovery":[59],"transformation":[61],"of":[62,84,94,131,176,185],"agents.":[65],"A":[66,183],"linking":[68,123,133],"antimicrobial":[69],"(LAMPs),":[71],"launched":[72],"in":[73,157,162],"2013,":[74],"serves":[75],"comprehensive":[78],"supply":[81],"exhaustive":[82],"information":[83],"on":[86,143],"single":[88,125],"platform.":[89],"LAMP2,":[90],"updated":[92,140,202],"version":[93,203],"LAMP,":[95],"holds":[96],"23":[97],"253":[98],"unique":[99],"sequences":[101,121],"expands":[103],"link":[105],"16":[106],"public":[107],"databases.":[109],"In":[110],"current":[112],"version,":[113],"there":[114],"are":[115,179],"than":[117,129,172],"50%":[118],"(12":[119],"236)":[120],"only":[122],"45%":[130],"two":[134],"links.":[138],"Additionally,":[139],"categories":[141],"based":[142],"primary":[144],"structure,":[145],"collection,":[146],"composition,":[147],"source":[148],"function":[150],"integrated":[153,161],"LAMP2.":[155],"Peptides":[156],"LAMP2":[158],"8":[163],"major":[164],"functional":[165,169],"classes":[166],"38":[168],"activities.":[170],"More":[171],"89%":[173],"(20":[174],"909)":[175],"experimentally":[180],"validated":[181],"peptides.":[182],"total":[184],"1924":[186],"references":[187],"were":[188],"extracted":[189],"evidence":[194],"supporting":[196],"activity":[198],"cytotoxicity.":[200],"will":[204],"be":[205],"helpful":[206],"scientific":[209],"community.":[210]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":41},{"year":2024,"cited_by_count":23},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":3}],"updated_date":"2026-07-25T09:21:30.201066","created_date":"2025-10-10T00:00:00"}