{"id":"https://openalex.org/W2093126354","doi":"https://doi.org/10.1093/comjnl/bxn021","title":"Serum Proteomic Abnormality Predating Screen Detection of Ovarian Cancer","display_name":"Serum Proteomic Abnormality Predating Screen Detection of Ovarian Cancer","publication_year":2008,"publication_date":"2008-04-04","ids":{"openalex":"https://openalex.org/W2093126354","doi":"https://doi.org/10.1093/comjnl/bxn021","mag":"2093126354"},"language":"en","primary_location":{"id":"doi:10.1093/comjnl/bxn021","is_oa":false,"landing_page_url":"https://doi.org/10.1093/comjnl/bxn021","pdf_url":null,"source":{"id":"https://openalex.org/S44643521","display_name":"The Computer Journal","issn_l":"0010-4620","issn":["0010-4620","1460-2067"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Computer Journal","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035540038","display_name":"Alex Gammerman","orcid":"https://orcid.org/0000-0002-9671-8441"},"institutions":[{"id":"https://openalex.org/I184558857","display_name":"Royal Holloway University of London","ror":"https://ror.org/04g2vpn86","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I184558857"]},{"id":"https://openalex.org/I4210113298","display_name":"London Women's Clinic","ror":"https://ror.org/024en4403","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210113298"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"A. Gammerman","raw_affiliation_strings":["Institute for Women's Health, University College London, UK","Computer Learning Research Centre, Royal Holloway, University of London, UK"],"affiliations":[{"raw_affiliation_string":"Institute for Women's Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Computer Learning Research Centre, Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063978613","display_name":"Vladimir Vovk","orcid":"https://orcid.org/0000-0003-2602-6877"},"institutions":[{"id":"https://openalex.org/I184558857","display_name":"Royal Holloway University of London","ror":"https://ror.org/04g2vpn86","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I184558857"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"V. Vovk","raw_affiliation_strings":["Computer Learning Research Centre, Royal Holloway, University of London, UK","Computer Learning Research Centre Royal Holloway, University of London, UK"],"affiliations":[{"raw_affiliation_string":"Computer Learning Research Centre, Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]},{"raw_affiliation_string":"Computer Learning Research Centre Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048326749","display_name":"Brian Burford","orcid":null},"institutions":[{"id":"https://openalex.org/I184558857","display_name":"Royal Holloway University of London","ror":"https://ror.org/04g2vpn86","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I184558857"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"B. Burford","raw_affiliation_strings":["Computer Learning Research Centre, Royal Holloway, University of London, UK","Computer Learning Research Centre Royal Holloway, University of London, UK"],"affiliations":[{"raw_affiliation_string":"Computer Learning Research Centre, Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]},{"raw_affiliation_string":"Computer Learning Research Centre Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086768742","display_name":"Ilia Nouretdinov","orcid":"https://orcid.org/0000-0002-5968-7228"},"institutions":[{"id":"https://openalex.org/I184558857","display_name":"Royal Holloway University of London","ror":"https://ror.org/04g2vpn86","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I184558857"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"I. Nouretdinov","raw_affiliation_strings":["Computer Learning Research Centre, Royal Holloway, University of London, UK","Computer Learning Research Centre Royal Holloway, University of London, UK"],"affiliations":[{"raw_affiliation_string":"Computer Learning Research Centre, Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]},{"raw_affiliation_string":"Computer Learning Research Centre Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070080426","display_name":"Zhiyuan Luo","orcid":"https://orcid.org/0000-0002-3336-3751"},"institutions":[{"id":"https://openalex.org/I184558857","display_name":"Royal Holloway University of London","ror":"https://ror.org/04g2vpn86","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I184558857"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Z. Luo","raw_affiliation_strings":["Computer Learning Research Centre, Royal Holloway, University of London, UK","Computer Learning Research Centre Royal Holloway, University of London, UK"],"affiliations":[{"raw_affiliation_string":"Computer Learning Research Centre, Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]},{"raw_affiliation_string":"Computer Learning Research Centre Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003007752","display_name":"Alexey Chervonenkis","orcid":null},"institutions":[{"id":"https://openalex.org/I184558857","display_name":"Royal Holloway University of London","ror":"https://ror.org/04g2vpn86","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I184558857"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. Chervonenkis","raw_affiliation_strings":["Computer Learning Research Centre, Royal Holloway, University of London, UK","Computer Learning Research Centre Royal Holloway, University of London, UK"],"affiliations":[{"raw_affiliation_string":"Computer Learning Research Centre, Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]},{"raw_affiliation_string":"Computer Learning Research Centre Royal Holloway, University of London, UK","institution_ids":["https://openalex.org/I184558857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109145207","display_name":"M.D. Waterfield","orcid":null},"institutions":[{"id":"https://openalex.org/I4210106789","display_name":"Ludwig Cancer Research","ror":"https://ror.org/01e473h50","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210106789","https://openalex.org/I4210150094"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Waterfield","raw_affiliation_strings":["Ludwig Institute for Cancer Research, University College London, UK"],"affiliations":[{"raw_affiliation_string":"Ludwig Institute for Cancer Research, University College London, UK","institution_ids":["https://openalex.org/I4210106789","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016772331","display_name":"Rainer Cramer","orcid":"https://orcid.org/0000-0002-8037-2511"},"institutions":[{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]},{"id":"https://openalex.org/I4210106789","display_name":"Ludwig Cancer Research","ror":"https://ror.org/01e473h50","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210106789","https://openalex.org/I4210150094"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R. Cramer","raw_affiliation_strings":["BioCentre and Department of Chemistry, University of Reading, UK","Ludwig Institute for Cancer Research, University College London, UK"],"affiliations":[{"raw_affiliation_string":"BioCentre and Department of Chemistry, University of Reading, UK","institution_ids":["https://openalex.org/I71052956"]},{"raw_affiliation_string":"Ludwig Institute for Cancer Research, University College London, UK","institution_ids":["https://openalex.org/I4210106789","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009347072","display_name":"Paul Tempst","orcid":"https://orcid.org/0000-0002-6680-3987"},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Tempst","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, New York, USA","Memorial Sloan-Kettering Cancer Center New York USA"],"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, USA","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center New York USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053250467","display_name":"Josep Villanueva","orcid":"https://orcid.org/0000-0003-1396-9470"},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Villanueva","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, New York, USA","Memorial Sloan-Kettering Cancer Center New York USA"],"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, USA","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center New York USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029169332","display_name":"Misha Kabir","orcid":"https://orcid.org/0000-0003-3991-1015"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I4210113298","display_name":"London Women's Clinic","ror":"https://ror.org/024en4403","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210113298"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Kabir","raw_affiliation_strings":["Institute for Women's Health, University College London, UK","Institute for Women\u2019s Health, University College London, UK"],"affiliations":[{"raw_affiliation_string":"Institute for Women's Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute for Women\u2019s Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049422711","display_name":"St\u00e9phane Camuzeaux","orcid":"https://orcid.org/0000-0002-4614-4662"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I4210113298","display_name":"London Women's Clinic","ror":"https://ror.org/024en4403","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210113298"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Camuzeaux","raw_affiliation_strings":["Institute for Women's Health, University College London, UK","Institute for Women\u2019s Health, University College London, UK"],"affiliations":[{"raw_affiliation_string":"Institute for Women's Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute for Women\u2019s Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020418534","display_name":"John F. Timms","orcid":"https://orcid.org/0000-0002-4507-835X"},"institutions":[{"id":"https://openalex.org/I4210113298","display_name":"London Women's Clinic","ror":"https://ror.org/024en4403","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210113298"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Timms","raw_affiliation_strings":["Institute for Women's Health, University College London, UK","Institute for Women\u2019s Health, University College London, UK"],"affiliations":[{"raw_affiliation_string":"Institute for Women's Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute for Women\u2019s Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081082018","display_name":"Usha Menon","orcid":"https://orcid.org/0000-0003-3708-1732"},"institutions":[{"id":"https://openalex.org/I4210113298","display_name":"London Women's Clinic","ror":"https://ror.org/024en4403","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210113298"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"U. Menon","raw_affiliation_strings":["Institute for Women's Health, University College London, UK","Institute for Women\u2019s Health, University College London, UK"],"affiliations":[{"raw_affiliation_string":"Institute for Women's Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute for Women\u2019s Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007042275","display_name":"Ian Jacobs","orcid":"https://orcid.org/0000-0002-5005-2672"},"institutions":[{"id":"https://openalex.org/I4210113298","display_name":"London Women's Clinic","ror":"https://ror.org/024en4403","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210113298"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"I. Jacobs","raw_affiliation_strings":["Institute for Women's Health, University College London, UK","Institute for Women\u2019s Health, University College London, UK"],"affiliations":[{"raw_affiliation_string":"Institute for Women's Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute for Women\u2019s Health, University College London, UK","institution_ids":["https://openalex.org/I4210113298","https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5035540038"],"corresponding_institution_ids":["https://openalex.org/I184558857","https://openalex.org/I4210113298","https://openalex.org/I45129253"],"apc_list":{"value":2635,"currency":"GBP","value_usd":3232},"apc_paid":null,"fwci":2.1427,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.86350202,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"52","issue":"3","first_page":"326","last_page":"333"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9901000261306763,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9851999878883362,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abnormality","display_name":"Abnormality","score":0.8290566802024841},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"Ovarian cancer","score":0.7074856162071228},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.384719580411911},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3578168749809265},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.27609601616859436}],"concepts":[{"id":"https://openalex.org/C50965678","wikidata":"https://www.wikidata.org/wiki/Q2724302","display_name":"Abnormality","level":2,"score":0.8290566802024841},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.7074856162071228},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.384719580411911},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3578168749809265},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27609601616859436},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1093/comjnl/bxn021","is_oa":false,"landing_page_url":"https://doi.org/10.1093/comjnl/bxn021","pdf_url":null,"source":{"id":"https://openalex.org/S44643521","display_name":"The Computer Journal","issn_l":"0010-4620","issn":["0010-4620","1460-2067"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Computer Journal","raw_type":"journal-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1000.8593","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1000.8593","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://comjnl.oxfordjournals.org/content/52/3/326.full.pdf","raw_type":"text"},{"id":"pmh:oai:centaur.reading.ac.uk:11258","is_oa":false,"landing_page_url":"https://centaur.reading.ac.uk/11258/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402273","display_name":"CentAUR (University of Reading)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I71052956","host_organization_name":"University of Reading","host_organization_lineage":["https://openalex.org/I71052956"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:177478","is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/177478/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"   COMPUT J , 52  (3)   326 - 333.   (2009)      ","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/5","display_name":"Gender equality","score":0.5199999809265137}],"awards":[],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320325311","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1965237521","https://openalex.org/W1965302510","https://openalex.org/W1984503480","https://openalex.org/W2038747720","https://openalex.org/W2051301080","https://openalex.org/W2097617341","https://openalex.org/W2097822207","https://openalex.org/W2112899213","https://openalex.org/W2128440298","https://openalex.org/W2138482047","https://openalex.org/W2145453941","https://openalex.org/W2157492758"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725","https://openalex.org/W2148612803"],"abstract_inverted_index":{"Ovarian":[0],"cancer":[1,33,59],"is":[2,67,169],"characterized":[3],"by":[4],"vague,":[5],"non-specific":[6],"symptoms,":[7],"advanced":[8],"stage":[9],"at":[10,111],"diagnosis":[11,128],"and":[12,34,41,117],"poor":[13],"overall":[14],"survival.":[15],"A":[16],"nested":[17],"case":[18],"control":[19],"study":[20,66],"was":[21],"undertaken":[22],"on":[23],"stored":[24],"serial":[25],"serum":[26,39,79,155],"samples":[27,80],"from":[28,150],"women":[29,70],"who":[30],"developed":[31],"ovarian":[32,58,130,164],"healthy":[35],"controls":[36,118],"(matched":[37],"for":[38,73,160],"processing":[40],"storage":[42],"conditions":[43],"as":[44,46,49],"well":[45],"attributes":[47],"such":[48],"age)":[50],"in":[51,123],"a":[52,84,101,138],"pilot":[53],"randomized":[54],"controlled":[55],"trial":[56],"of":[57,64,125,129,163],"screening.":[60],"The":[61,78,166],"unique":[62],"feature":[63],"this":[65],"that":[68,99,147,175],"the":[69,112,126,151,172],"were":[71],"screened":[72],"up":[74,119],"to":[75,90,120,170],"7":[76],"years.":[77],"underwent":[81],"prefractionation":[82],"using":[83],"reversed-phase":[85],"batch":[86],"extraction":[87],"protocol":[88],"prior":[89],"MALDI-TOF":[91],"MS":[92,103],"data":[93],"acquisition.":[94],"Our":[95],"exploratory":[96],"analysis":[97],"shows":[98],"combining":[100],"single":[102,139],"peak":[104,140],"with":[105],"CA125":[106,142],"allows":[107],"statistically":[108],"significant":[109],"discrimination":[110],"5%":[113],"level":[114],"between":[115],"cases":[116],"12":[121],"months":[122],"advance":[124],"original":[127],"cancer.":[131,165],"Such":[132],"combinations":[133],"work":[134],"much":[135],"better":[136],"than":[137],"or":[141],"alone.":[143],"This":[144],"paper":[145],"demonstrates":[146],"mass":[148],"spectra":[149],"low":[152],"molecular":[153],"weight":[154],"proteome":[156],"carry":[157],"information":[158],"useful":[159],"early":[161,177],"detection":[162,178],"next":[167],"step":[168],"identify":[171],"specific":[173],"biomarkers":[174],"make":[176],"possible.":[179]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":5}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}