{"id":"https://openalex.org/W2988426147","doi":"https://doi.org/10.1093/bioinformatics/btz847","title":"Differentiating isoform functions with collaborative matrix factorization","display_name":"Differentiating isoform functions with collaborative matrix factorization","publication_year":2019,"publication_date":"2019-11-12","ids":{"openalex":"https://openalex.org/W2988426147","doi":"https://doi.org/10.1093/bioinformatics/btz847","mag":"2988426147","pmid":"https://pubmed.ncbi.nlm.nih.gov/32176770"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz847","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz847","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110954531","display_name":"Keyao Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I142108993","display_name":"Southwest University","ror":"https://ror.org/01kj4z117","country_code":"CN","type":"education","lineage":["https://openalex.org/I142108993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Keyao Wang","raw_affiliation_strings":["College of Computer and Information Science, Southwest University , Chongqing 400715, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Computer and Information Science, Southwest University , Chongqing 400715, China","institution_ids":["https://openalex.org/I142108993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100384767","display_name":"Jun Wang","orcid":"https://orcid.org/0000-0002-5890-0365"},"institutions":[{"id":"https://openalex.org/I142108993","display_name":"Southwest University","ror":"https://ror.org/01kj4z117","country_code":"CN","type":"education","lineage":["https://openalex.org/I142108993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Wang","raw_affiliation_strings":["College of Computer and Information Science, Southwest University , Chongqing 400715, China"],"raw_orcid":"https://orcid.org/0000-0002-5890-0365","affiliations":[{"raw_affiliation_string":"College of Computer and Information Science, Southwest University , Chongqing 400715, China","institution_ids":["https://openalex.org/I142108993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090148962","display_name":"Carlotta Domeniconi","orcid":"https://orcid.org/0000-0003-2140-9596"},"institutions":[{"id":"https://openalex.org/I162714631","display_name":"George Mason University","ror":"https://ror.org/02jqj7156","country_code":"US","type":"education","lineage":["https://openalex.org/I162714631"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlotta Domeniconi","raw_affiliation_strings":["Department of Computer Science, George Mason University , Fairfax, VA 22030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, George Mason University , Fairfax, VA 22030, USA","institution_ids":["https://openalex.org/I162714631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000755750","display_name":"Xiangliang Zhang","orcid":"https://orcid.org/0000-0002-3574-5665"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":true,"raw_author_name":"Xiangliang Zhang","raw_affiliation_strings":["Computer, Electrical, and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology , Thuwal 23955, SA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer, Electrical, and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology , Thuwal 23955, SA","institution_ids":["https://openalex.org/I71920554"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027082940","display_name":"Guoxian Yu","orcid":"https://orcid.org/0000-0002-1667-6705"},"institutions":[{"id":"https://openalex.org/I142108993","display_name":"Southwest University","ror":"https://ror.org/01kj4z117","country_code":"CN","type":"education","lineage":["https://openalex.org/I142108993"]},{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["CN","SA"],"is_corresponding":true,"raw_author_name":"Guoxian Yu","raw_affiliation_strings":["College of Computer and Information Science, Southwest University , Chongqing 400715, China","Computer, Electrical, and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology , Thuwal 23955, SA"],"raw_orcid":"https://orcid.org/0000-0002-1667-6705","affiliations":[{"raw_affiliation_string":"College of Computer and Information Science, Southwest University , Chongqing 400715, China","institution_ids":["https://openalex.org/I142108993"]},{"raw_affiliation_string":"Computer, Electrical, and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology , Thuwal 23955, SA","institution_ids":["https://openalex.org/I71920554"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5000755750","https://openalex.org/A5027082940"],"corresponding_institution_ids":["https://openalex.org/I142108993","https://openalex.org/I71920554"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.9051,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.86714146,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"36","issue":"6","first_page":"1864","last_page":"1871"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.6258000135421753,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.6258000135421753,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.07660000026226044,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.0649000033736229,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-isoform","display_name":"Gene isoform","score":0.8255327343940735},{"id":"https://openalex.org/keywords/focus","display_name":"Focus (optics)","score":0.5844603776931763},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.58180832862854},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.573943555355072},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5606639981269836},{"id":"https://openalex.org/keywords/key","display_name":"Key (lock)","score":0.5480684041976929},{"id":"https://openalex.org/keywords/granularity","display_name":"Granularity","score":0.48194408416748047},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.47873708605766296},{"id":"https://openalex.org/keywords/matrix","display_name":"Matrix (chemical analysis)","score":0.4307101368904114},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"Alternative splicing","score":0.42541056871414185},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.31914687156677246},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2558109164237976},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.06389498710632324},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.06342923641204834}],"concepts":[{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.8255327343940735},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.5844603776931763},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.58180832862854},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.573943555355072},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5606639981269836},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.5480684041976929},{"id":"https://openalex.org/C177774035","wikidata":"https://www.wikidata.org/wiki/Q1246948","display_name":"Granularity","level":2,"score":0.48194408416748047},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.47873708605766296},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.4307101368904114},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.42541056871414185},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31914687156677246},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2558109164237976},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.06389498710632324},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.06342923641204834},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btz847","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz847","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32176770","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32176770","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:repository.kaust.edu.sa:10754/662248","is_oa":false,"landing_page_url":"http://hdl.handle.net/10754/662248","pdf_url":null,"source":{"id":"https://openalex.org/S4306401596","display_name":"King Abdullah University of Science and Technology Repository (King Abdullah University of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I71920554","host_organization_name":"King Abdullah University of Science and Technology","host_organization_lineage":["https://openalex.org/I71920554"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17","score":0.4300000071525574}],"awards":[{"id":"https://openalex.org/G3605984960","display_name":null,"funder_award_id":"XDJK2019B024","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G5564147583","display_name":"\u9762\u5411\u53ef\u53d8\u526a\u63a5\u5f02\u6784\u4f53\u529f\u80fd\u9884\u6d4b\u7684\u6570\u636e\u6574\u5408\u65b9\u6cd5\u7814\u7a76","funder_award_id":"61872300","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G659245102","display_name":null,"funder_award_id":"61873214","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1486817521","https://openalex.org/W1568341953","https://openalex.org/W1784654175","https://openalex.org/W1895597370","https://openalex.org/W1902027874","https://openalex.org/W1981509058","https://openalex.org/W1983120861","https://openalex.org/W2011920499","https://openalex.org/W2027266161","https://openalex.org/W2027898937","https://openalex.org/W2041399050","https://openalex.org/W2043292259","https://openalex.org/W2088338354","https://openalex.org/W2102278945","https://openalex.org/W2104005232","https://openalex.org/W2110119381","https://openalex.org/W2127119915","https://openalex.org/W2155804510","https://openalex.org/W2168103112","https://openalex.org/W2171184528","https://openalex.org/W2227395312","https://openalex.org/W2259938310","https://openalex.org/W2340210804","https://openalex.org/W2345998082","https://openalex.org/W2426363820","https://openalex.org/W2559588208","https://openalex.org/W2604808360","https://openalex.org/W2904341255","https://openalex.org/W2954055267","https://openalex.org/W2956050535","https://openalex.org/W6765999633"],"related_works":["https://openalex.org/W2904939684","https://openalex.org/W2012312817","https://openalex.org/W2081598294","https://openalex.org/W3010322897","https://openalex.org/W2056672569","https://openalex.org/W2090969926","https://openalex.org/W4385462331","https://openalex.org/W2009697542","https://openalex.org/W2053656597","https://openalex.org/W2011070917"],"abstract_inverted_index":{"MOTIVATION:":[0],"Isoforms":[1],"are":[2,129,166,306],"alternatively":[3],"spliced":[4,108],"mRNAs":[5],"of":[6,23,31,40,90,116,127,164,170,188,249,285,296],"genes.":[7,210],"They":[8,92],"can":[9,282],"be":[10],"translated":[11],"into":[12,190],"different":[13],"functional":[14,21,50,162],"proteoforms,":[15],"and":[16,60,106,113,131,180,200,218,243,256,270,278],"thus":[17],"greatly":[18],"increase":[19],"the":[20,29,37,55,58,63,66,75,88,95,107,124,161,176,196,215,225,235,238,246,276],"diversity":[22],"protein":[24],"variants":[25],"(or":[26,33],"proteoforms).":[27],"Differentiating":[28],"functions":[30,70,89,115,274,284],"isoforms":[32,109,287],"proteoforms)":[34],"helps":[35],"understanding":[36],"underlying":[38],"pathology":[39],"various":[41],"complex":[42],"diseases":[43],"at":[44,57,65,253,275,300,308],"a":[45,104,145],"deeper":[46],"granularity.":[47],"Since":[48],"existing":[49,250],"genomic":[51],"databases":[52],"uniformly":[53],"record":[54,62],"annotations":[56,64,126,163,187],"gene-level,":[59],"rarely":[61],"isoform-level,":[67,277],"differentiating":[68],"isoform":[69,153,177],"is":[71,298],"more":[72],"challenging":[73],"than":[74],"traditional":[76],"gene-level":[77],"function":[78,202],"prediction.":[79],"RESULTS:":[80],"Several":[81],"approaches":[82,121],"have":[83,140],"been":[84],"proposed":[85],"to":[86,151,193,207,222],"differentiate":[87,283],"isoforms.":[91,172],"generally":[93],"follow":[94],"multi-instance":[96],"learning":[97],"paradigm":[98],"by":[99,204,252],"viewing":[100],"each":[101],"gene":[102],"as":[103,110],"bag":[105],"its":[111],"instances,":[112],"push":[114],"bags":[117],"onto":[118],"instances.":[119],"These":[120],"implicitly":[122],"assume":[123],"collected":[125],"genes":[128,165,266],"complete":[130],"only":[132],"integrate":[133],"multiple":[134],"RNA-seq":[135],"datasets.":[136],"As":[137],"such,":[138],"they":[139],"compromised":[141],"performance.":[142],"We":[143,259],"propose":[144],"data":[146,178,182,305],"integrative":[147],"solution":[148],"(called":[149],"DisoFun)":[150],"Differentiate":[152],"Functions":[154],"with":[155,272,288],"collaborative":[156],"matrix":[157,179,183,226],"factorization.":[158,227],"DisoFun":[159,233,262,281,297],"assumes":[160],"aggregated":[167],"from":[168],"those":[169],"key":[171,198],"It":[173],"collaboratively":[174],"factorizes":[175],"gene-term":[181],"(storing":[184],"Gene":[185,219],"Ontology":[186,220],"genes)":[189],"low-rank":[191],"matrices":[192],"simultaneously":[194],"explore":[195],"latent":[197],"isoforms,":[199],"achieve":[201],"prediction":[203],"aggregating":[205],"predictions":[206],"their":[208,286],"originating":[209],"In":[211],"addition,":[212],"it":[213],"leverages":[214],"PPI":[216],"network":[217],"structure":[221],"further":[223,260],"coordinate":[224],"Extensive":[228],"experimental":[229],"results":[230],"show":[231],"that":[232,280],"improves":[234],"area":[236,244],"under":[237,245],"receiver":[239],"operating":[240],"characteristic":[241],"curve":[242,248],"precision-recall":[247],"solutions":[251],"least":[254],"7.7":[255],"28.9%,":[257],"respectively.":[258],"investigate":[261],"on":[263],"four":[264],"exemplar":[265],"(LMNA,":[267],"ADAM15,":[268],"BCL2L1":[269],"CFLAR)":[271],"known":[273],"observed":[279],"90.5%":[289],"accuracy.":[290],"AVAILABILITY":[291],"AND":[292],"IMPLEMENTATION:":[293],"The":[294],"code":[295],"available":[299,307],"mlda.swu.edu.cn/codes.php?name=DisoFun.":[301],"SUPPLEMENTARY":[302],"INFORMATION:":[303],"Supplementary":[304],"Bioinformatics":[309],"online.":[310]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":5}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}