{"id":"https://openalex.org/W2991743543","doi":"https://doi.org/10.1093/bioinformatics/btz825","title":"<b>An efficient approach based on multi-sources information to predict circRNA</b>\u2013<b>disease associations using deep convolutional neural network</b>","display_name":"<b>An efficient approach based on multi-sources information to predict circRNA</b>\u2013<b>disease associations using deep convolutional neural network</b>","publication_year":2019,"publication_date":"2019-11-21","ids":{"openalex":"https://openalex.org/W2991743543","doi":"https://doi.org/10.1093/bioinformatics/btz825","mag":"2991743543","pmid":"https://pubmed.ncbi.nlm.nih.gov/31793982"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz825","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz825","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/13/4038/33459060/btz825.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/36/13/4038/33459060/btz825.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100436059","display_name":"Lei Wang","orcid":"https://orcid.org/0000-0003-0184-307X"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Wang","raw_affiliation_strings":["Xinjiang Technical Institute of Physics and Chemistry , Chinese Academy of Sciences, Urumqi 830011, China"],"affiliations":[{"raw_affiliation_string":"Xinjiang Technical Institute of Physics and Chemistry , Chinese Academy of Sciences, Urumqi 830011, China","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019805735","display_name":"Zhu\u2010Hong You","orcid":"https://orcid.org/0000-0003-1266-2696"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhu-Hong You","raw_affiliation_strings":["Xinjiang Technical Institute of Physics and Chemistry , Chinese Academy of Sciences, Urumqi 830011, China"],"affiliations":[{"raw_affiliation_string":"Xinjiang Technical Institute of Physics and Chemistry , Chinese Academy of Sciences, Urumqi 830011, China","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017713277","display_name":"Yu\u2010An Huang","orcid":"https://orcid.org/0000-0002-5346-2394"},"institutions":[{"id":"https://openalex.org/I14243506","display_name":"Hong Kong Polytechnic University","ror":"https://ror.org/0030zas98","country_code":"HK","type":"education","lineage":["https://openalex.org/I14243506"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Yu-An Huang","raw_affiliation_strings":["Department of Computing , Hong Kong Polytechnic University, Hong Kong 999077, China"],"affiliations":[{"raw_affiliation_string":"Department of Computing , Hong Kong Polytechnic University, Hong Kong 999077, China","institution_ids":["https://openalex.org/I14243506"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060381913","display_name":"De-Shuang Huang","orcid":"https://orcid.org/0000-0002-6759-2691"},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"De-Shuang Huang","raw_affiliation_strings":["Institute of Machine Learning and Systems Biology , School of Electronics and Information Engineering, Tongji University, Shanghai 201804, China"],"affiliations":[{"raw_affiliation_string":"Institute of Machine Learning and Systems Biology , School of Electronics and Information Engineering, Tongji University, Shanghai 201804, China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107049960","display_name":"Keith C. C. Chan","orcid":"https://orcid.org/0000-0001-7962-6564"},"institutions":[{"id":"https://openalex.org/I14243506","display_name":"Hong Kong Polytechnic University","ror":"https://ror.org/0030zas98","country_code":"HK","type":"education","lineage":["https://openalex.org/I14243506"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Keith C C Chan","raw_affiliation_strings":["Department of Computing , Hong Kong Polytechnic University, Hong Kong 999077, China"],"affiliations":[{"raw_affiliation_string":"Department of Computing , Hong Kong Polytechnic University, Hong Kong 999077, China","institution_ids":["https://openalex.org/I14243506"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5019805735"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106108"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":9.1627,"has_fulltext":false,"cited_by_count":156,"citation_normalized_percentile":{"value":0.98684949,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"36","issue":"13","first_page":"4038","last_page":"4046"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.7260160446166992},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7212600708007812},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.6400659084320068},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.625274121761322},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5416849255561829},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.5077870488166809},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.4969494640827179},{"id":"https://openalex.org/keywords/kernel","display_name":"Kernel (algebra)","score":0.4556364119052887},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.44624796509742737},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.4403284788131714},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.4236522316932678},{"id":"https://openalex.org/keywords/semantic-similarity","display_name":"Semantic similarity","score":0.4184481203556061},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3552164137363434},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1380515992641449}],"concepts":[{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.7260160446166992},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7212600708007812},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.6400659084320068},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.625274121761322},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5416849255561829},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.5077870488166809},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.4969494640827179},{"id":"https://openalex.org/C74193536","wikidata":"https://www.wikidata.org/wiki/Q574844","display_name":"Kernel (algebra)","level":2,"score":0.4556364119052887},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.44624796509742737},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.4403284788131714},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.4236522316932678},{"id":"https://openalex.org/C130318100","wikidata":"https://www.wikidata.org/wiki/Q2268914","display_name":"Semantic similarity","level":2,"score":0.4184481203556061},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3552164137363434},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1380515992641449},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btz825","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz825","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/13/4038/33459060/btz825.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31793982","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31793982","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz825","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz825","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/13/4038/33459060/btz825.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1472446628","display_name":null,"funder_award_id":"2019M653804","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G3158980518","display_name":null,"funder_award_id":"61572506","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3588239447","display_name":null,"funder_award_id":"61702444","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5294168992","display_name":null,"funder_award_id":"61873212","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G53239543","display_name":null,"funder_award_id":"2018-XBQNXZ-B-008","funder_id":"https://openalex.org/F4320328015","funder_display_name":"West Light Foundation of the Chinese Academy of Sciences"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320328015","display_name":"West Light Foundation of the Chinese Academy of Sciences","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2991743543.pdf","grobid_xml":"https://content.openalex.org/works/W2991743543.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W1967087625","https://openalex.org/W1987390907","https://openalex.org/W1990748933","https://openalex.org/W1991082489","https://openalex.org/W1993717606","https://openalex.org/W2018780815","https://openalex.org/W2029838682","https://openalex.org/W2031593782","https://openalex.org/W2034587103","https://openalex.org/W2058835062","https://openalex.org/W2064165694","https://openalex.org/W2065260846","https://openalex.org/W2104960492","https://openalex.org/W2106029302","https://openalex.org/W2109393499","https://openalex.org/W2111072639","https://openalex.org/W2125224183","https://openalex.org/W2141222510","https://openalex.org/W2147806662","https://openalex.org/W2152705149","https://openalex.org/W2152719653","https://openalex.org/W2155653793","https://openalex.org/W2163605009","https://openalex.org/W2204741763","https://openalex.org/W2295882128","https://openalex.org/W2461928526","https://openalex.org/W2515463500","https://openalex.org/W2517357283","https://openalex.org/W2527999453","https://openalex.org/W2558825838","https://openalex.org/W2579420628","https://openalex.org/W2605363845","https://openalex.org/W2606895029","https://openalex.org/W2697319983","https://openalex.org/W2734945090","https://openalex.org/W2801121099","https://openalex.org/W2807602500","https://openalex.org/W2888239540","https://openalex.org/W2898991725","https://openalex.org/W2899436082","https://openalex.org/W2906953716","https://openalex.org/W2923922207","https://openalex.org/W2957180077","https://openalex.org/W2964114039","https://openalex.org/W2964951118","https://openalex.org/W4240367950","https://openalex.org/W6684191040","https://openalex.org/W6687978271","https://openalex.org/W6719428085","https://openalex.org/W6752457901"],"related_works":["https://openalex.org/W2375480909","https://openalex.org/W2353314428","https://openalex.org/W2012019886","https://openalex.org/W2388928357","https://openalex.org/W2166090428","https://openalex.org/W2381021552","https://openalex.org/W2114797768","https://openalex.org/W2380654781","https://openalex.org/W2176214140","https://openalex.org/W2516873349"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":23},{"year":2022,"cited_by_count":35},{"year":2021,"cited_by_count":52},{"year":2020,"cited_by_count":14},{"year":2017,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2019-12-13T00:00:00"}